کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8301378 1537679 2018 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Adiponectin AS lncRNA inhibits adipogenesis by transferring from nucleus to cytoplasm and attenuating Adiponectin mRNA translation
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Adiponectin AS lncRNA inhibits adipogenesis by transferring from nucleus to cytoplasm and attenuating Adiponectin mRNA translation
چکیده انگلیسی
Proposed mechanism by which AdipoQ AS lncRNA inhibits adipogenesis. A) In vitro effect and molecular mechanism of AdipoQ AS lncRNA. AdipoQ AS lncRNA transfers from nucleus to cytoplasm, inhibiting adipogenic differentiation through forming a sense/antisense RNA duplex to prevent translation of AdipoQ mRNA. B) In vivo effect of AdipoQ AS lncRNA. AdipoQ AS lncRNA and NOR decrease the WAT, BAT and liver TG in HFD mice, but NOR improves the GTT and ITT.189
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids - Volume 1863, Issue 4, April 2018, Pages 420-432
نویسندگان
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