Keywords: NIC; nicotine; JAK2; janus tyrosine kinase; STAT3; signal transducer and activator of transcription 3; SOCS3; suppressor of cytokine signaling 3; OB-R; leptin receptors; GD; gestational day; isSWAT; interscapular subcutaneous white adipose tissue; igSWAT;
مقالات ISI (ترجمه نشده)
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Keywords: ACAT; acyl-coenzyme A:cholesterol acyltransferases; BSH; bile salt hydrolase; CFU; colony-forming unit; FAS; fatty acid synthase; FXR; farnesoid X receptor; GA; gum Arabic; GLP; glucagon-like peptides; HDL-C; high density lipoproteins cholesterol; HFD; hi
Keywords: Resistin-like molecule; Macrophage; Helminth infection; T helper type 2; Toll-like Receptor 4; ABC; ATP-binding cassette transporter; ADD1; adipocyte determination and differentiation dependent factor 1; ADSF; adipocyte secreted factor; Akt (aka PKB); pro
Keywords: Plin; perilipin; PPAR; peroxisome proliferator-activated receptor; SREBP1c; sterol regulatory element-binding transcription factor 1c; ChREBP; carbohydrate response element binding protein; SCD1; stearoyl-CoA desaturase 1; ACSL1; long-chain acyl-CoA synth
Keywords: 18S; 18S ribosomal RNA; 36B4; acidic ribosomal protein 36B4; Acc1; acetyl-CoA carboxylase α; Acox1; acyl-CoA oxidase 1; Apob; apolipoprotein B; ARE; antioxidant response element; AST; aspartate aminotransferase; ALT; alanine aminotransferase; ATF4; activ
Dietary tea polyphenols ameliorate metabolic syndrome and memory impairment via circadian clock related mechanisms
Keywords: TP; tea polyphenols; DD; constant darkness; SCN; suprachiasmatic nucleus; LD; light-dark; CLOCK; circadian locomotor output cycles kaput; BMAL1; brain and muscle arnt-like protein-1; CRY; cryptochromes; REV-ERB; -; RORs; RAR-related orphan receptors; PE
Keywords: Caloric restriction; Adipose tissue; Fatty acid biosynthesis; SREBP1c;
Keywords: Ovariectomy; Hyperphagia; Triacylglycerol; Liver; Plasma; Desaturase; OVX + AL; ovariectomized rat with ad libitum access to food; OVX + PF; ovariectomized rat pair-fed to sham-operated rat; SHAM; sham-operated rat; VO2; volume of oxygen consumed; VCO2; v
Keywords: ACAT; acyl-CoA cholesterol acyltransferase; ACC; acetyl CoA carboxylases; ACLY; ATP citrate lyases; ACSL; acyl CoA synthetases long chain family; ADRP; adipose differentiation related protein; AGP; advanced glycation end products; AGPAT; acylglycerophosph
Keywords: ATIC; allylisothiocyanate; GLUT4; glucose transporter 4; mtDNA; mitochondrial DNA; FFA; free fatty acid; OCR; Oxygen consumption rate; DMEM; Dulbecco's Modified Eagle's medium; FBS; fetal bovine serum; 2-NBDG; 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) amin
Keywords: Acaca; acetyl CoA carboxylase-α; aLKO; adipocyte LPL knockout; BAT; brown adipose tissue; Dio2; type 2 thyroid hormone deiodinase; ChREBP; carbohydrate response element binding protein; COX-2; cyclooxygenase-2; DNL; de novo lipogenesis; Elovl; fatty acid
FTO promotes SREBP1c maturation and enhances CIDEC transcription during lipid accumulation in HepG2 cells
Keywords: FTO; SREBP1c; CIDEC; Lipogenesis; Hepatocyte;
Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces hepatic steatosis and endoplasmic reticulum stress by inducing nuclear factor erythroid-derived 2-related factor 2 nuclear translocation
Keywords: Glucagon-like peptide-1; Exendin-4; Nuclear factor erythroid-derived 2-related factor 2; Endoplasmic reticulum stress; Nonalcoholic fatty liver disease; ATF6; Activation transcription factor-6; Bip; Binding immunoglobulin protein; CHOP; C/EBP homologous p
Epigenetic mechanisms contribute to decrease stearoyl-CoA desaturase 1 expression in the liver of dairy cows after prolonged feeding of high-concentrate diet
Keywords: SARA; epigenetic regulation; SREBP1c; chromatin remodeling;
Adiponectin AS lncRNA inhibits adipogenesis by transferring from nucleus to cytoplasm and attenuating Adiponectin mRNA translation
Keywords: AdipoQ; Adiponectin; AS lncRNA; antisense long noncoding RNA; FISH; fluorescence in situ hybridization; RPA; ribonuclease protection assay; iWAT; inguinal white adipose tissue; eWAT; epididymal white adipose tissue; BAT; brown adipose tissue; TG; triglyce
Coordinate regulation by transcription factors and DNA methylation in the core promoter region of SIRT6 in bovine adipocytes
Keywords: SIRT6; Promoter; Transcriptional regulation; DNA methylation; Bovine; Adipocyte; qPCR; real-time quantitative; CEBPβ; CCAAT enhancer binding protein beta; PAX6; paired box 6; KLF2; Kruppel-like factor 2; CMYB; myb proto-oncogene protein; NRF1; nuclear re
High-fat diet alters PAS kinase regulation by fasting and feeding in liver
Keywords: ACC; acetyl CoA carboxylase; Akt/PKB; protein kinase B; CHREBP; carbohydrate-responsive element-binding protein; CPT1-A; carnitine palmitoyltransferase 1A; DAPI; 4,6-diamidino-2-phenylindole; FAS; fatty acid synthase; FOXO1; forkhead box protein O1; GCK;
Curcumin enhances LXRα in an AMP-activated protein kinase-dependent manner in human macrophages
Keywords: LXR; liver X receptor; ABCA1; ATP-binding cassette transporter A1; ABCG1; ATP-binding cassette transporter G1; SREBP1c; sterol response element binding protein 1c; AMPK; AMP-activated protein kinase; PMA; phorbol myristate acetate; fMLP; formyl-Met-Leu-Ph
GCN2 deficiency protects against high fat diet induced hepatic steatosis and insulin resistance in mice
Keywords: ALT; alanine transaminase; AST; aspartate transaminase; Atgl; adipose triglyceride lipase; AU; arbitrary unit; AUC; area under the curve; BSA; bovine serum albumin; CHOP; C/EBP homologous protein; Cpt2; carnitine palmitoyltransferase 2; DHE; dihydroethidi
Raffinose from Costus speciosus attenuates lipid synthesis through modulation of PPARs/SREBP1c and improves insulin sensitivity through PI3K/AKT
Keywords: Anti-diabetes; Anti-adipogenesis; Lipid metabolism; Insulin signaling; ACC; acetyl-CoA carboxylase; ACO; Acyl CoA Oxidase; Comp C; Compound C; CSEW; Costus speciosus ethanolic water extract; DMEM; Dulbecco's Modified Eagle Medium; FAS; fatty acid synthase
Long non-coding RNAs regulation in adipogenesis and lipid metabolism: Emerging insights in obesity
Keywords: lncRNAs; Obesity; White adipogenesis; Brown adipocyte differentiation; Lipid metabolism; Therapeutics; WAT; white adipose tissue; BAT; brown adipose tissue; Pparg; peroxisome proliferator-activated receptor γ; Cebpa; CCAAT/enhancer binding protein α; Fa
Chronic administration of saturated fats and fructose differently affect SREBP activity resulting in different modulation of Nrf2 and Nlrp3 inflammasome pathways in mice liver
Keywords: ACC; acetyl CoA carboxylase; ApoB; apolipoprotein B; COX-1; cytochrome c oxidase subunit 1; CPT1-l; carnitine palmitoyltrasnferase; FAS; fatty acid synthase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GCLC; glutamate-cysteine ligase catalytic; GCL
28-Homocastasterone down regulates blood glucose, cholesterol, triglycerides, SREBP1c and activates LxR expression in normal & diabetic male rat
Keywords: 28-Homocastasterone; Blood glucose; Cholesterol; Triglyceride; Liver x Receptor; 28-HC; 28-homocastasterone; LxR; Liver x Receptor; ABCT; ATP-binding cassette transporters; SREBP1c; sterol regulatory element binding protein-1c; TNF-α; Tumor necrosis fact
EGCG ameliorates diet-induced metabolic syndrome associating with the circadian clock
Keywords: EGCG; Epigallocatechin gallate; CLOCK; Circadian locomotor output cycles kaput; BMAL1; Brain and muscle arnt-like protein-1; CRY; Cryptochromes; PER; Period; SIRT1; Sirtuin 1; PGC1α; Peroxisome proliferator-activated receptor coactivator 1-α; IR; Insuli
Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis
Keywords: Triglyceride; Insulin Signaling; Gene Regulation; Signal Transduction; DNL; de novo lipogenesis; HFD; high-fat diet; KCTD17; potassium channel tetramerization domain containing 17; KO; knockout; LC/MS-MS; liquid chromatography-tandem mass spectrometry;
Thermogenesis, fatty acid synthesis with oxidation, and inflammation in the brown adipose tissue of ob/ob (â/â) mice
Keywords: AKT; protein kinase B; BAT; brown adipose tissue; beta3-AR; beta 3 adrenergic receptor; BM; body mass; CD36; cluster of differentiation 36; CPT1b; carnitine palmitoyltransferase 1b; EE; energy expenditure; FABP4; fatty acid binding protein 4; FAS; fatty a
Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury
Keywords: Binge ethanol consumption; FGF21; Chronic ethanol consumption; Alcoholic liver disease; ACSS2; acyl-coenzyme a synthetase short-chain family member 2; ADH 1 and 2; alcohol dehydrogenase 1 and 2; ALDH1α1; aldehyde dehydrogenase 1 alpha 1; ALD; alcoholic l
A-type ECG and EGCG dimers inhibit 3T3-L1 differentiation by binding to cholesterol in lipid rafts
Keywords: A-type ECG and EGCG dimers; Cholesterol; Disruption; Lipid rafts; 3T3-L1 preadipocytes differentiation; A-type ECG dimer; epicatechin-3-gallate-(4βâ8, 2βâOâ7)-epicatechin-3-gallate; A-type EGCG dimer; epigallocatechin-3-gallate-(4βâ8, 2βâOâ
DBZ is a putative PPARγ agonist that prevents high fat diet-induced obesity, insulin resistance and gut dysbiosis
Keywords: ACC; acetyl-CoA carboxylase; ADRB; adrenoreceptor beta; BAT; brown adipose tissue; CPT1β; carnitine palmitoyltransferase 1 beta; DBZ; danshensu bingpian zhi; Epi-WAT; epididymal white adipose tissue; FATP; fatty acid transport protein; FAS; fatty acid sy
Altered cellular redox status, sirtuin abundance and clock gene expression in a mouse model of developmentally primed NASH
Keywords: NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; HF; high fat; C; control; sirt1; sirtuin 1; sirt3; sirtuin 3; Clock; circadian locomotor output cycles kaput; Per2; Bmal1 (also called Arntl1), period 2; Cry2; cryptochrome 2;
Platelet-activating factor and hydrogen peroxide exert a dual modulatory effect on the transcription of LXRα and its target genes in human neutrophils
Keywords: LXRα; liver X receptor; PAF; platelet-activating factor; H2O2; hydrogen peroxide; ABCA1; ATP-binding cassette transporter A1; ABCG1; ATP-binding cassette transporter G1; SREBP1c; sterol regulatory element-binding protein 1c; NF-κB; nuclear factor κB; R
ATF4 regulates SREBP1c expression to control fatty acids synthesis in 3T3-L1 adipocytes differentiation
Keywords: USP7; ubiquitin specific peptidase 7; TRB3; tribbles homolog 3; PTM; post-translational modification; IBMX; 1-methyl-3-isobutylxanthine; DEX; dexamethasone; INS; insulin; ATF4; USP7; TRB3; SREBP1c; Transcription; PTM;
RNA-binding protein HuD reduces triglyceride production in pancreatic β cells by enhancing the expression of insulin-induced gene 1
Keywords: RNA-binding protein; HuD; Triglyceride; INSIG1; SREBP1c;
Ingestion of eicosapentaenoic acid in the early stage of social isolation reduces a fibroblast growth factor 21 resistant state independently of body weight in KKAy mice
Keywords: EPA; FGF21; GLP-1; Hyperglycemia; Hypertriglyceridemia; ChREBP; SREBP1c; Periostin; gp78; Notch; Lipogenesis;
SH2 domain-containing inositol 5-phosphatase (SHIP2) regulates de-novo lipogenesis and secretion of apoB100 containing lipoproteins in HepG2 cells
Keywords: De-novo lipogenesis; VLDL; SH2 domain-containing inositol 5-phosphatase (SHIP2); Insulin resistance; HepG2; Liver; ACC; acyl COA carboxylase; FAS; fatty acid synthase; FOXO1; forkhead box protein O1; GFP; green fluorescent protein; MTP; microsomal transfe
SH2 domain-containing inositol 5-phosphatase (SHIP2) inhibition ameliorates high glucose-induced de-novo lipogenesis and VLDL production through regulating AMPK/mTOR/SREBP1 pathway and ROS production in HepG2 cells
Keywords: AMPK; AMP-activated protein kinase; ACC; Acyl COA Carboxylase; BSA; Bovine Serum Albumin; DHE; Dihydroethidium; DPI; Diphenylene iodonium; ERK; Extracellular signal-regulated kinase; FAS; Fatty Acid Synthase; FBS; Fetal bovine serum; FOXO1; Forkhead box p
The genus Sida L. - A traditional medicine: Its ethnopharmacological, phytochemical and pharmacological data for commercial exploitation in herbal drugs industry
Keywords: ABTS; 2,2â²-azinobis-3-ethylbenzothiazoline-6-sulfonic acid; AGS; human gastric adenocarcinoma; AIU; aspirin induced ulcer; ALP; alkaline phosphatase; ALT; serum alanine aminotransferase; AP; aerial part; APPLIU; aspirin plus pylorus ligation induced ulc
Shifts in dietary carbohydrate-lipid exposure regulate expression of the non-alcoholic fatty liver disease-associated gene PNPLA3/adiponutrin in mouse liver and HepG2 human liver cells
Keywords: ACC1; acetyl CoA-carboxylase; ALA; α-linolenic acid; BSA; bovine serum albumin; ChREBP; carbohydrate response element binding protein; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; HC; high-carbohydrate; HF; high fat; LE; lipid emulsion; LA; lin
Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH)
Keywords: ATGL; adipose triglyceride lipase; ACC1; acetyl-CoA carboxylase; ACSL1; long-chain fatty-acid-coenzyme A ligase; ap2/FABP4; adipocyte protein 2/fatty acid binding protein 4; ATP5B; ATP synthase, HÂ + transporting mitochondrial F1 complex, beta subunit; BA
Effects of fisetin supplementation on hepatic lipogenesis and glucose metabolism in Sprague-Dawley rats fed on a high fat diet
Keywords: PPARγ; peroxisome proliferator-activated receptor gamma; SREBP-1c; sterol regulatory element binding transcription factor 1c; SCD-1; stearoyl-Coenzyme A desaturase 1; ACC; acetyl-CoA carboxylase; FAS; fatty acid synthase; ATPCL; ATP citrate lyase; G6Pase
IL-17 inhibits adipogenesis in part via C/EBPα, PPARγ and Krüppel-like factors
Keywords: KLF; Krüppel like factor; IL-; interleukin; GR; glucocorticoid receptor; Egr-2; early growth response gene2 (KROX 20); Srebp1c; sterol regulatory element binding protein 1c; PPARγ; peroxisome proliferator-activated receptor; GRE; glucocorticoid response
Piperine reverses high fat diet-induced hepatic steatosis and insulin resistance in mice
Keywords: HFD; high-fat diet; FFA; free fatty acid; ALT; alanine aminotransferase; AST; aspartate aminostransferase; AdipoR1; adiponectin receptor-1; AdipoR2; adiponectin receptor-2; AMPK; AMP-activated protein kinase; CPT1; carnitine palmitoyltransferase 1; CD36;
Wild bitter gourd increased metabolic rate and up-regulated genes related to mitochondria biogenesis and UCP-1 in mice
Keywords: ACADL1; acyl-Coenzyme A dehydrogenase, long-chain; ACSL3; acyl-CoA synthetase long-chain family member 3; AMPK; AMP activated protein kinase; BAT; brown adipose tissue; BG; bitter gourd; BGP; bitter gourd powder; CLN; 9c, 11t, 13t-conjugated linolenic aci
Inhibition of preadipocyte differentiation and lipid accumulation by 7-O-galloyl-d-sedoheptulose treatment in 3T3-L1 adipocytes
Keywords: 7-O-Galloyl-d-sedoheptulose; 3T3-L1 cell; Adipogenesis; AMPK; SREBP1c; PPARγ; C/EBPα
Alpha-linolenic acid increases cholesterol efflux in macrophage-derived foam cells by decreasing stearoyl CoA desaturase 1 expression: evidence for a farnesoid-X-receptor mechanism of action
Keywords: ALA; SCD1; FXR; SREBP1C; Cholesterol efflux; Foam cell;
Piperine, an LXRα antagonist, protects against hepatic steatosis and improves insulin signaling in mice fed a high-fat diet
Keywords: AMPK; AMP-activated protein kinase; LXRα; liver X receptor α; CD36; CD36 antigen; SREBP1c; sterol regulatory element binding protein 1c; ChREBPα; carbohydrate response element binding protein α; ER; endoplasmic reticulum; HFD; high fat diet; BIP; bind
Comprehensive proteomic analysis of host cell lipid rafts modified by HBV infection
Keywords: 2DE; 2 dimensional polyacrylamide gel electrophoresis; CAV1; caveolin 1; DMEM; Dulbecco's modified eagle medium; DMSO; dimethyl sulfoxide; DRMs; detergent-resistant membranes; ER; endoplasmic reticulum; ESI-Q-TOF; electrospray ionization quadrupole time-o
The Cell Biology of the Unfolded Protein Response
Keywords: ER; endoplasmic reticulum; HRI; heme-regulated kinase; IFN; interferon; PKR; protein kinase; SREBP1c; sterol regulatory element-binding protein 1c; UPR; unfolded protein response; Xbp1; X-box binding protein 1;
Anti-obesity potential of Clerodendron glandulosum.Coleb leaf aqueous extract
Keywords: LEP; leptin; PPARγ-2; peroxisome proliferator-activated receptor gamma isoform 2; SREBP1c; sterol regulatory element binding proteins isoform 1c; FAS; fatty acid synthase; CPT-1; carnitine parmitoyltransferase 1; HFD; high fat diet; G3PDH; glyceraldehyde
The link between fibroblast growth factor 21 and sterol regulatory element binding protein 1c during lipogenesis in hepatocytes
Keywords: FGF21; Lipogenesis; SREBP1c; Promoter; Hepatocyte