Keywords: دست کشیدن; c-Kit; Cardiac; Transgenic; Knock-in; Reporter;
مقالات ISI دست کشیدن (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: دست کشیدن; Sleeping beauty transposon; Designer nucleases; Knockout; Knock-in; Transgenic rabbit;
Keywords: دست کشیدن; AD; Alzheimer's disease; APP; amyloid precursor protein; KI; knock-in; WT; wild-type; CTF-β; C terminal fragment-β; GFAP; glial fibrillary acidic protein; rmANOVA; repeated measures analysis of variance; MANOVA; multivariate analysis of variance; ROI;
Keywords: دست کشیدن; AD; Alzheimer's disease; ADCA; autosomal dominant cerebellar ataxia; AMPA receptor; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; APP; amyloid precursor protein; Atx2mut; mutant ataxin-2; Aβ peptides; amyloid beta peptides; BACE1; beta
Keywords: دست کشیدن; ACE; angiotensin-converting enzyme; ANF; atrial natriuretic factor; BNP; brain natriuretic peptide; DCM-CD; dilated cardiomyopathy with conduction defects; EDMD; Emery-Dreifuss muscular dystrophy; EHT; engineered heart tissue; KI; knock-in; KO; knock-ou
Keywords: دست کشیدن; KI; knock-in; KO; knockout; AMPA; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate; DOPA; dihydroxyphenylalanine; DRD; dopa-responsive dystonia; GABA; γ-aminobutyric acid; 5-HT; serotonin; HVA; homovanillic acid; TH; tyrosine hydroxylase; D2R; dopami
Comparing successful gene knock-in efficiencies of CRISPR/Cas9 with ZFNs and TALENs gene editing systems in bovine and dairy goat fetal fibroblasts
Keywords: دست کشیدن; myostatin (MSTN); β-casein (CSN2); bovine fetal fibroblasts; CRISPR/Cas9; dairy goat fetal fibroblasts; eGFP; hFat-1; knock-in; mutation efficiency; TALENs; ZFNs;
Cartilage oligomeric matrix protein: COMPopathies and beyond
Keywords: دست کشیدن; ATF6; activating transcription factor 6; ATP; adenosine triphosphate; BiP; binding immunoglobulin protein; BMD; bone mineral density; Chop; Mouse c/ebp homologous protein genes; CHOP; c/ebp homologous protein; COL9A1; human collagen type 9 Alpha 1 chain g
Histone H3 lysine 4 methyltransferase KMT2D
Keywords: دست کشیدن; KMT2D; histone-lysine N-methyltransferase 2D; H3K4; histone H3 lysine 4; H3K27; histone H3 lysine 27; H3K4me1/2/3; H3K4 mono-, di- and tri-methylation; H3K27ac; H3K27 acetylation; WRAD; WDR5, RbBP5, ASH2L, and DPY30; KO; knockout; KI; knock-in; TF; transc
A glycine transporter 2-Cre knock-in mouse line for glycinergic neuron-specific gene manipulation
Keywords: دست کشیدن; Glycine; Glycinergic neuron; GLYT2; Cre recombinase; Knock-in;
Forebrain knock-out of torsinA reduces striatal free-water and impairs whole-brain functional connectivity in a symptomatic mouse model of DYT1 dystonia
Keywords: دست کشیدن; cKO; conditional knock-out; dMRI; diffusion magnetic resonance imaging; FC; functional connectivity; FW; free-water; KI; knock-in; KO; knock-out; MDT; free-water corrected mean diffusivity; rsfMRI; resting-state functional magnetic resonance imaging; SCI;
CommunicationH3K4 Methyltransferase Activity Is Required for MLL4 Protein Stability
Keywords: دست کشیدن; H3K4; lysine 4 of histone H3; HMT; histone methyltransferase; MLL; mixed-lineage leukemia; KO; knockout; ES; embryonic stem; KI; knock-in; K4M; lysine 4-to-methionine mutation; H3.3K4M; histone H3.3 carrying lysine 4-to-methionine mutation; qRT-PCR; quant
Generation of a TALEN-mediated, p63 knock-in in human induced pluripotent stem cells
Keywords: دست کشیدن; hiPS cell(s); human induced pluripotent stem cell(s); KI; knock-in; TAp63; transactivating p63; ÎNp63; N-terminally truncated p63; ZFNs; zinc-finger nucleases; TALENs; transcription activator-like effector nucleases; SEAM; self-formed ectodermal autonomo
Sirt1 suppresses Wnt/βCatenin signaling in liver cancer cells by targeting βCatenin in a PKAα-dependent manner
Keywords: دست کشیدن; KO; knock-out; KI; knock-in; βTrCP; beta-transducin repeat containing E3 ubiquitin protein ligase; RING; really interesting new gene; S; Ser; T; Thr; A; alanine; R; arginine; mSirt1; mouse Sirt1; mSIRT1-KI; mouse Sirt1 knock-in; mSirt1-LKO; mSirt1-liver
ReviewGenetic strategies to analyze primary TRP channel-expressing cells in mice
Keywords: دست کشیدن; TRP channels; TRPM5; Gene targeting; Homologous recombination; Knock-in; Genetic labeling; Internal ribosomal entry site; Cre recombinase; ROSA26; ÏGFP;
Hyperpolarization-activated current Ih in mouse trigeminal sensory neurons in a transgenic mouse model of familial hemiplegic migraine type-1
Keywords: دست کشیدن; α,β-meATP; α,β-methylene-ATP; AP; action potential; DRG; dorsal root ganglia; CGRP; calcitonin gene-related peptide; FHM1; familial hemiplegic migraine type-1; HCN; hyperpolarization-activated cyclic nucleotide-gated channel; Ih; hyperpolarization-act
Genome editing using CRISPR/Cas9-based knock-in approaches in zebrafish
Keywords: دست کشیدن; Knock-in; CRISPR/Cas9; Genome editing; Homologous recombination; Non-homologous-end-joining; Zebrafish;
A roadmap for gene system development in Clostridium
Keywords: دست کشیدن; Restriction modification; Gene transfer; ClosTron; Allelic exchange; Counterselection marker; pyrE; Knock-out; Knock-in; Fluoroorotic acid;
Generation and validation of PAX7 reporter lines from human iPS cells using CRISPR/Cas9 technology
Keywords: دست کشیدن; PAX7; Human iPS cells; GFP reporter; Cas9; dCas9; CRISPR; Cas9 nickase; Knock-in; Homologous recombination
A novel luciferase knock-in reporter system for studying transcriptional regulation of the human Sox2 gene
Keywords: دست کشیدن; Sox2; TALEN; Knock-in; Homologous recombination; Gene editing;
Efficient genomic correction methods in human iPS cells using CRISPR-Cas9 system
Keywords: دست کشیدن; iPS cells; CRISPR; Genome editing; Knock-out; Knock-in; Gene correction;
Span poly-L-arginine nanoparticles are efficient non-viral vectors for PRPF31 gene delivery: An approach of gene therapy to treat retinitis pigmentosa
Keywords: دست کشیدن; Nanoparticle; Span; Gene therapy; Ophthalmology; Retinitis pigmentosa; AAV; adeno-associated viral; AAV2; adeno-associated viral vectors serotype 2; adRP; autosomal dominant retinitis pigmentosa; ANOVA; analysis of variance; c/d; cycles/degree; DAPI; 4â²
Role of AMPK in regulation of LC3 lipidation as a marker of autophagy in skeletal muscle
Keywords: دست کشیدن; AICAR; 5-aminoimidazole-4-carboxamide riboside; AMP; adenosine monophosphate; AMPK; 5â²AMP activated protein kinase; ANOVA; Analysis of Variance; ATG; autophagy related gene; ATP; adenosine triphosphate; BCA; bicinchoninic acid; BSA; bovine serum albumin
Differential cerebellar GABAA receptor expression in mice with mutations in CaV2.1 (P/Q-type) calcium channels
Keywords: دست کشیدن; EA-2; Episodic Ataxia type 2; FHM1; Familial Hemiplegic Migraine type 1; GABAA; γ-aminobutyric acid type A; KI; knock-in; PC; Purkinje cell; qPCR; quantitative polymerase-chain reaction; tg; Tottering; tgln; Leaner; tgrol; Rolling Nagoya; gamma aminobuty
A new humanized ataxin-3 knock-in mouse model combines the genetic features, pathogenesis of neurons and glia and late disease onset of SCA3/MJD
Keywords: دست کشیدن; Ataxin-3; Mouse; Knock-in; Knockin; SCA3; MJD; Ataxia; Spinocerebellar; CAG repeats; Serpina3n; Polyglutamine;
The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease
Keywords: دست کشیدن; αSyn; alpha-synuclein; ALP; autophagy/lysosomal degradation pathway; CSF; cerebral spinal fluid; ERK5; extracellular-signal-regulated kinase 5; IL; interleukin; KI; knock-in; KO; knockout; LPS; lipopolysaccharide; LRRK2; leucine rich repeat kinase 2; MHC
Specific expression of FOXP2 in cerebellum improves ultrasonic vocalization in heterozygous but not in homozygous Foxp2 (R552H) knock-in pups
Keywords: دست کشیدن; BAC; bacterial artificial chromosome; FOX; forkhead box; KI; knock-in; KO; knock-out; Pcp2; purkinje cell protein-2; USV; ultrasonic vocalization; Foxp2; Ultrasonic vocalization; Speech-language disorder;
Genetic and pharmacological evidence that G2019S LRRK2 confers a hyperkinetic phenotype, resistant to motor decline associated with aging
Keywords: دست کشیدن; BAC; bacterial artificial chromosome; DA; dopamine; KI; knock-in; KD; kinase dead; LRRK2; leucine-rich repeat kinase 2; PD; Parkinson's disease; ROC; Ras Of Complex; WT; wild-type; Aging; D1994S knock-in; G2019S knock-in; H-1152; LRRK2 kinase-dead; LRRK2;
Necroptosis, in vivo detection in experimental disease models
Keywords: دست کشیدن; (AD); Alzheimer's disease; (AKI); acute kidney injury; (CLP); cecal ligation and puncture; (CypD); cyclophilin D; (ConA); Concanavalin-A; (DAI); DNA-dependent activator of IFN-regulatory factors; (DAMPs); damage-associated molecular patterns; (HMGB1); hig
Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1α in vivo
Keywords: دست کشیدن; AA; arachidonic acid; ALT; alanine aminotransferase; BSO; l-buthionine sulfoximine; CYP2E1; cytochrome P450 2E1; GSH; reduced glutathione; HE; hematoxylin-eosin; 4-HNE; 4-hydroxynonenal; HIF; hypoxia-inducible factor; HPH-2; HIF prolyl hydroxylase 2; IH
Functional significance of glycogen synthase kinase-3 regulation by serotonin
Keywords: دست کشیدن; FST; forced swim test; GSK3; glycogen synthase kinase-3; 5-HT1A; serotonin type 1A receptors; i.p.; intraperitoneal; KI; knock-in; PI3K; phosphoinositide 3-kinase; PKA; protein kinase A; PKC; protein kinase C; WT; wild type; Serotonin; 5-HT1A; Fluoxetine;
Longitudinal analysis of the behavioural phenotype in Hdh(CAG)150 Huntington's disease knock-in mice
Keywords: دست کشیدن; Huntington's disease; Knock-in; HdhQ150; Behaviour; Phenotype; Cognitive; Motor
Five choice serial reaction time performance in the HdhQ92 mouse model of Huntington's disease
Keywords: دست کشیدن; Huntington's disease; HdhQ92 mouse; 5-Choice serial reaction time task; Attention; Knock-in; 9-Hole box; Operant tests
Longitudinal analysis of the behavioural phenotype in HdhQ92 Huntington's disease knock-in mice
Keywords: دست کشیدن; Huntington's disease; Knock-in; Q92; Behaviour; Phenotype; Cognitive; Motor
Light and electron microscopic characterization of the evolution of cellular pathology in the Hdh(CAG)150 Huntington's disease knock-in mouse
Keywords: دست کشیدن; Huntington's disease; Aggregations; Inclusions; HdhQ150/Q150; Knock-in; Transmission electron microscope (TEM)
Comparative analysis of pathology and behavioural phenotypes in mouse models of Huntington's disease
Keywords: دست کشیدن; Huntington's disease; Knock-in; Behaviour; Neuropathology; Gene; Phenotype
Operant-based instrumental learning for analysis of genetically modified models of Huntington's disease
Keywords: دست کشیدن; Huntington's disease; Operant; Cognition; Transgenic; Knock-in
Generation of knockout mice expressing a GFP-reporter under the control of the Lmx1a locus
Keywords: دست کشیدن; Mouse; Lmx1a; GFP; Knock-in; Homologous recombination; dreher; In situ hybridization; Immunohistochemistry
TIF1β association with HP1 is essential for post-gastrulation development, but not for Sertoli cell functions during spermatogenesis
Keywords: دست کشیدن; HP1; TIF1β/KAP-1/TRIM28; Knock-in; Embryonic lethality; Nuclear organization; Chromatin; Mouse;
The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity
Keywords: دست کشیدن; Epidermal morphogenesis; Grainy head-like; Skin barrier; Wound repair; Eyelid fusion; Knockout; Knock-in;
Genetic mouse models for bone studies-Strengths and limitations
Keywords: دست کشیدن; Transgenic; Knock-out; Knock-in; Conditional knock-out; Gene deletion; Mouse model; Cre-lox system; Cre recombinase; Bone promoters;
Regional neural tube closure defined by the Grainy head-like transcription factors
Keywords: دست کشیدن; Neural tube closure; Grainy head-like; Spina bifida; Exencephaly; Knock-out; Knock-in;
A new and simple approach for genotyping Alzheimer's disease presenilin-1 mutant knock-in mice
Keywords: دست کشیدن; Presenilin-1; Genotyping; SSCP; Knock-in; Alzheimer's disease
Demonstration of functional α4-containing nicotinic receptors in the medial habenula
Keywords: دست کشیدن; Addiction; Ion channel; C-fos; Knock-in; mRNA;
NDUFS4: Creation of a mouse model mimicking a Complex I disorder
Keywords: دست کشیدن; Gene targeting; Knock-in; Leigh syndrome; Leigh’s disease
Mos1 transposition as a tool to engineer the Caenorhabditis elegans genome by homologous recombination
Keywords: دست کشیدن; Genome engineering; Knockout; Knock-in; Protein tagging; Homologous recombination; Caenorhabditis elegans; MosTIC; DNA double-strand break repair
Prominin-1/CD133 Marks Stem Cells and Early Progenitors in Mouse Small Intestine
Keywords: دست کشیدن; EGFP; enhanced green fluorescent protein; ES; embryonic stem; EST; expressed sequence tag; FACS; fluorescence-activated cell sorting; IRES; internal ribosome entry site; KI; knock-in; Lgr5; leucine-rich-repeat-containing G-protein-coupled receptor 5; PBS;
Next generation tools for high-throughput promoter and expression analysis employing single-copy knock-ins at the Hprt1 locus
Keywords: دست کشیدن; Embryonic stem cells; Gene targeting; Vectors; Genomics; Hprt1; Knock-in; Mice; Promoter regions; Transgenic
Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes
Keywords: دست کشیدن; Huntington's disease; Trinucleotide; Instability; Repeat; Striatum; Repair; Mouse; Knock-in; Pathogenesis
A novel series of vectors for chromosomal integration in fission yeast
Keywords: دست کشیدن; PCR, polymerase chain reaction; G418, geneticin; ORF, open reading frame; MCS, multiple cloning siteSchizosaccharomyces pombe; Plasmid; Gene expression; Homologous recombination; Knock-in