Keywords: کانال کلسیم L نوع; Fibromodulin; L-type calcium channel; T-type calcium channel; Myoblast; Myogenesis;
مقالات ISI کانال کلسیم L نوع (ترجمه نشده)
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Keywords: کانال کلسیم L نوع; SL; sarcolemma; SR; saroplasmic reticulum; SERCA; sarcoplasmic/endoplasmic reticulum calcium ATPase; NCX; Na+/Ca2+ exchanger; EC; excitation-contraction; AP; action potential; LCC; L-type calcium channel; HIP; human amylin transgenic; NFAT; nuclear fact
Keywords: کانال کلسیم L نوع; Heart; Tissue engineering; Myocardium; Biophysical properties; Force of contraction; Force frequency relationship; Calcium handling; T-tubulation; Maturation; AAV; adenovirus-associated virus; CSQ2; Calsequestrin 2; DMS; dynamic mechanical stimulation; EH
Keywords: کانال کلسیم L نوع; Crystalline lens; Ionizing radiation; DNA repair factors; Nontargeted effects; Inflammation; Tumor suppressors; A-bomb; atomic-bomb; Acvr1; activin A type 1 receptor; AP; apurinic/apyrimidinic; APE1; apurinic/apyrimidinic endonuclease 1; AQP; aquaporin; A
Keywords: کانال کلسیم L نوع; Sepsis; Sepsis-induced cardiomyopathy; Calcium; Excitation-contraction coupling; L-type calcium channel; SERCA; Na+/Ca2+ exchange;
Keywords: کانال کلسیم L نوع; Stress; Calcium; L-type calcium channel; Na+/Ca2+ exchanger;
A novel CACNA1C mutation identified in a patient with Timothy syndrome without syndactyly exerts both marked loss- and gain-of-function effects
Keywords: کانال کلسیم L نوع; Electrophysiology; Genetics; Long QT syndrome; L-type calcium channel; Timothy syndrome;
Effects of the iron chelator deferiprone and the T-type calcium channel blocker efonidipine on cardiac function and Ca2+ regulation in iron-overloaded thalassemic mice
Keywords: کانال کلسیم L نوع; ATP; adenosine triphosphate; [Ca2+]i; intracellular calcium; CICR; calcium-induced calcium release; DFP; deferiprone; EF; ejection fraction; EFO; efonidipine; FE; iron diet; FS; fraction shortening; HRV; heart rate variability; HT; β-thalassemic type; IC
Effect of fluoride exposure on mRNA expression of cav1.2 and calcium signal pathway apoptosis regulators in PC12 cells
Keywords: کانال کلسیم L نوع; Fluoride exposure; PC12 cell; L-type calcium channel; CAMKII; Cell apoptosis;
Enhanced effect of VEGF165 on L-type calcium currents in guinea-pig cardiac ventricular myocytes
Keywords: کانال کلسیم L نوع; VEGF; vascular endothelial growth factor; LTCC; L-type calcium channel; VEGFR2; VEGF type-2 receptor; ICa,L; L-type calcium currents; AP; action potential; APD; action potential duration; EC coupling; excitation-contraction coupling; IV; current-voltage;
Roles of L-type calcium channels (CaV1.2) and the distal C-terminus (DCT) in differentiation and mineralization of rat dental apical papilla stem cells (rSCAPs)
Keywords: کانال کلسیم L نوع; CaV1.2; voltage-gated calcium channels; DCT; distal C-terminus (DCT) of CaV1.2; rSCAPs; rat dental apical papilla stem cells; RT-PCR; real-time PCR; Ica; inward Ca2+ currents; HA/TCP; hydroxyapatite/tricalcium phosphate; DPSCs; dental pulp stem cells; shR
The role of L-type calcium channels in mouse oocyte maturation, activation and early embryonic development
Keywords: کانال کلسیم L نوع; Oocyte; Meiosis; Spindle; L-type calcium channel;
Calcium/calmodulin-dependent serine protein kinase CASK modulates the L-type calcium current
Keywords: کانال کلسیم L نوع; L-Type calcium channel; CASK; Regulation; Open probability;
Mechanisms of the cyclic nucleotide cross-talk signaling network in cardiac L-type calcium channel regulation
Keywords: کانال کلسیم L نوع; Phosphodiesterases; Cyclic nucleotides; Signaling network; L-type calcium channel; Cardiac myocytes; Computational model;
The Phenotypic Spectrum of a Mutation Hotspot Responsible for the Short QT Syndrome
Keywords: کانال کلسیم L نوع; channelopathy; genetics; short QT syndrome; sudden cardiac death; therapy; AF; atrial fibrillation; AP; action potential; ECG; electrocardiogram; ER; early repolarization; GWAS; genome-wide association studies; ICD; implantable cardioverter-defibrillator;
Isosteviol prevents the prolongation of action potential in hypertrophied cardiomyoctyes by regulating transient outward potassium and L-type calcium channels
Keywords: کانال کلسیم L نوع; Isosteviol; Cardiac hypertrophy; Transient outward potassium channel; L-type calcium channel;
Regulation of cardiac CACNB2 by microRNA-499: Potential role in atrial fibrillation
Keywords: کانال کلسیم L نوع; AF; atrial fibrillation; Ago; Argonaute; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; LTCC; L-type calcium channel; miR-499; microRNA-499; miRISC; microRNA-inducing silencing complex; CACNA1C; voltage-dependent calcium channel α-1C subunit; CACNB2; v
Computational approaches to understand the adverse drug effect on potassium, sodium and calcium channels for predicting TdP cardiac arrhythmias
Keywords: کانال کلسیم L نوع; ANN; Artificial Neural Network; CASH; Cardiac Arrest Study Hamburg; CAST; Cardiac Arrhythmia Suppression Trial; Cav1.2; L-Type calcium channel; CiPA; Comprehensive in vitro Proarrhythmic Assay; CSRC; Cardiac Safety Research Consortium; DHPs; 4-Aryl-1,4-di
S-nitrosothiols dilate the mesenteric artery more potently than the femoral artery by a cGMP and L-type calcium channel-dependent mechanism
Keywords: کانال کلسیم L نوع; S-nitrosothiol; L-type calcium channel; NO/cGMP pathway; Fetus; SheepSNOs, S-nitrosothiols; sGC, soluble guanylyl cyclase; L-Ca2+ channel, L-type calcium channel; BKCa, large-conductance Ca2+-activated K+ channel; PKG, cGMP-dependent protein kinase; EDHF,
Novel long QT syndrome-associated missense mutation, L762F, in CACNA1C-encoded L-type calcium channel imparts a slower inactivation tau and increased sustained and window current
Keywords: کانال کلسیم L نوع; CACNA1C; the CACNA1C-encoded α1c α-subunit of the L-type calcium channel; COTS; cardiac-only Timothy syndrome; LQTS; long QT syndrome; LTCC; L-type calcium channel; SCD; sudden cardiac death; SIDS; sudden infant death syndrome; TS; Timothy syndrome; CAC
The Role of the L-Type Ca2+ Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic Cardiomyopathy
Keywords: کانال کلسیم L نوع; calcium; cardiomyopathy; L-type calcium channel; mitochondria[Ca2+]i, intracellular calcium; HCM, hypertrophic cardiomyopathy; ICa-L, L-type Ca2+ channel; MHC, myosin heavy chain; VDAC, voltage-dependent anion channel; Ψm, mitochondrial membrane potential
The effects of vasoactive peptide urocortin 2 on hemodynamics in spontaneous hypertensive rat and the role of L-type calcium channel and CRFR2
Keywords: کانال کلسیم L نوع; Urocortin; Spontaneously hypertension; L-type calcium channel; Corticotropin releasing factor; Patch clamp
Characterization of lysophosphatidylcholine-induced changes of intracellular calcium in Drosophila S2 cells
Keywords: کانال کلسیم L نوع; Drosophila S2 cells; Lysophosphatidylcholine; Intracellular calcium; L-type calcium channel; Inositol triphosphate receptor
Cav1.2 of L-type Calcium Channel Is a Key Factor for the Differentiation of Dental Pulp Stem Cells
Keywords: کانال کلسیم L نوع; Cav1.2; DCT; L-type calcium channel; rat dental pulp stem cells
L-type calcium channels contribute to 5-HT3-receptor-evoked CaMKIIα and ERK activation and induction of emesis in the least shrew (Cryptotis parva)
Keywords: کانال کلسیم L نوع; 5-HT3 receptor; L-type calcium channel; Emesis; Calcium-induced calcium release; CaMKII; ERK1/2; Area postrema; Intestine; Enterochromaffin cells; Immunoprecipitation; Colocalization; Nifedipine (PubChem CID: 4485); 2-methyl-5-HT (PubChem CID: 1574);
L-type calcium channel blockers and substance P induce angiogenesis of cortical vessels associated with beta-amyloid plaques in an Alzheimer mouse model
Keywords: کانال کلسیم L نوع; Alzheimer; Beta-amyloid plaque; Reactive astrocytes; Vessels; L-type calcium channel; Substance P; Angiogenesis;
Impaired calcium-calmodulin-dependent inactivation of Cav1.2 contributes to loss of sarcoplasmic reticulum calcium release refractoriness in mice lacking calsequestrin 2
Keywords: کانال کلسیم L نوع; Calsequestrin; Calmodulin; Calcium release restitution; L-type calcium channel; Sarcoplasmic reticulum;
Modulation of L-type Ca2+ channel activity by neuronal nitric oxide synthase and myofilament Ca2+ sensitivity in cardiac myocytes from hypertensive rat
Keywords: کانال کلسیم L نوع; L-type calcium channel; nNOS; Hypertension; Myofilament Ca2+ sensitivity; Ca2+-dependent inactivation; Rate-dependency;
Differential CaMKII regulation by voltage-gated calcium channels in the striatum
Keywords: کانال کلسیم L نوع; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; CaMKII; calcium/calmodulin-dependent protein kinase II; LTCC; L-type calcium channel; MSN; medium spiny neuron; RTCC; R-type calcium channel; TTCC; T-type calcium channel; VGCC; voltag
Successful reduction of off-target hERG toxicity by structural modification of a T-type calcium channel blocker
Keywords: کانال کلسیم L نوع; T-type calcium channel blocker; hERG; L-type calcium channel; Pharmacokinetics;
Predicting changes in cardiac myocyte contractility during early drug discovery with in vitro assays
Keywords: کانال کلسیم L نوع; Cardiac drug safety; Radioligand-binding; L-type calcium channel; Automated electrophysiology; Contractility; Myocyte;
How Does Calcium Regulate Mitochondrial Energetics in the Heart? – New Insights
Keywords: کانال کلسیم L نوع; L-type calcium channel; Calcium; Cytoskeleton; Mitochondria; Metabolism
Electrical coupling between the human serotonin transporter and voltage-gated Ca2+ channels
Keywords: کانال کلسیم L نوع; Calcium channels; Calcium imaging; L-type calcium channel; N-type calcium channel; Monoamine transporters; Neurotransmitter transport; Skeletal muscle; Excitability;
L-type Ca2+ channel blockers inhibit the window contraction of mouse aorta segments with high affinity
Keywords: کانال کلسیم L نوع; Nifedipine (PubChem CID: 4485); Amlodipine (PubChem CID: 2162); Diltiazem HCl (PubChem CID: 62920); Verapamil HCl (PubChem CID: 62969); BAY K8644 (PubChem CID: 2303); Vascular reactivity; L-type calcium channel; Calcium channel blocker; Depolarization; Co
Modes of direct modulation by taurine of the glutamate NMDA receptor in rat cortex
Keywords: کانال کلسیم L نوع; Taurine; NMDA receptor; Spermine; Glycine; Prefrontal cortex; l-type calcium channel
AHNAK: The giant jack of all trades
Keywords: کانال کلسیم L نوع; AHNAK; L-type calcium channel; Dysferlin; Cardiac/skeletal muscle; Cancer; Metastasis;
Broad-spectrum antiemetic potential of the L-type calcium channel antagonist nifedipine and evidence for its additive antiemetic interaction with the 5-HT3 receptor antagonist palonosetron in the least shrew (Cryptotis parva)
Keywords: کانال کلسیم L نوع; Least shrew; Emesis; L-type calcium channel; 5-HT3 receptor; D2 receptor; NK1 receptor; M1 receptor; FPL 64176; Nifedipine; Palonosetron; 2-Me-5-HT; Apomorphine; Quinpirole; McN-A-343; Cisplatin
Spectrum of Cav1.4 dysfunction in congenital stationary night blindness type 2
Keywords: کانال کلسیم L نوع; L-type calcium channel; Cav1.4; Calcium channelopathy; Congenital stationary night blindness type 2;
Crosstalk between mitogen-activated protein kinases and mitochondria in cardiac diseases: Therapeutic perspectives
Keywords: کانال کلسیم L نوع; Heart; MAPK; Cardiac diseases; Mitochondria; Cell signaling; AngII; angiotensin II; CA; constitutively active; CHIP; C terminus of Hsc70-interacting protein; CT-1; cardiotrophin-1; ÎΨmit; mitochondrial membrane potential; DN; dominant negative; ERK1/2;
Calreticulin negatively regulates the surface expression of Cav1.3 L-type calcium channel
Keywords: کانال کلسیم L نوع; Calreticulin; L-type calcium channel; Cav1.3; Fetal myocytes;
Synthesis, ex vivo and in silico studies of 3-cyano-2-pyridone derivatives with vasorelaxant activity
Keywords: کانال کلسیم L نوع; 4H-Pyrans; 2-Pyridones; Microwave irradiation; Vasorelaxant activity; Docking score; L-type calcium channel;
Antagonism of L-type Ca2+ channels CaV1.3 and CaV1.2 by 1,4-dihydropyrimidines and 4H-pyrans as dihydropyridine mimics
Keywords: کانال کلسیم L نوع; 1,4-Dihydropyrimidines; 4H-Pyrans; CaV1.3 Ca2+ channel; CaV1.2 Ca2+ channel; L-type calcium channel; Parkinson's disease; FLIPR (Fluorometric imaging plate reader); Antagonism;
Polycystin-2 mutations lead to impaired calcium cycling in the heart and predispose to dilated cardiomyopathy
Keywords: کانال کلسیم L نوع; ADPKD; autosomal dominant polycystic kidney disease; APD; action potential duration; AV; atrioventricular; bpm; beats per minute; dpf; days post fertilization; CICR; calcium-induced calcium release; ER; endoplasmic reticulum; hpf; hours post fertilization
What can naturally occurring mutations tell us about Cav1.x channel function?
Keywords: کانال کلسیم L نوع; L-type calcium channel; Channelopathy; Structure-function analysis; Homology modeling;
Dynamin-2 mediates heart failure by modulating Ca2 +-dependent cardiomyocyte apoptosis
Keywords: کانال کلسیم L نوع; Heart failure; Dynamin; Apoptosis; Ca2Â + overload; L-type calcium channel;
Modular, efficient synthesis of asymmetrically substituted piperazine scaffolds as potent calcium channel blockers
Keywords: کانال کلسیم L نوع; N-type calcium channel; L-type calcium channel; Titanium catalysis; Zirconium catalysis; Substituted piperazines
5E- and 5Z-farnesylacetones from Sargassum siliquastrum as novel selective L-type calcium channel blockers
Keywords: کانال کلسیم L نوع; BASMCs, basilar arterial smooth muscle cells; VMCs, ventricular myocytesFarnesylacetones; L-type calcium channel; Vasodilatation; Hypertension
Simulations of calcium channel block by trivalent cations: Gd3+ competes with permeant ions for the selectivity filter
Keywords: کانال کلسیم L نوع; L-type calcium channel; Dihydropyridine receptor; Block; Permeation; Selectivity
Ahnak1 interaction is affected by phosphorylation of Ser-296 on Cavβ2
Keywords: کانال کلسیم L نوع; Ahnak; Cavβ2; L-type calcium channel; PKA phosphorylation; Protein-protein interaction;
Structure-activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitors
Keywords: کانال کلسیم L نوع; N-Type calcium channel; Trimethoxybenzyl piperazine; Pain; hERG potassium channel; L-Type calcium channel;