دانلود مقالات ISI درباره Lc3 + ترجمه فارسی

The palladacycle, AJ-5, exhibits anti-tumour and anti-cancer stem cell activity in breast cancer cells

Keywords: BCS; breast cancer cell; ER; oestrogen receptor; CSC; cancer stem cell; FACS; fluorescence activated cell sorting; γH2AX; gamma-histone 2AX; mTOR; mammalian/mechanistic target of rapamycin; PARP; poly(ADP-ribose) polymerase; BCL-2; B-cell lymphoma-2; Bax

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagy exacerbates caspase-dependent apoptotic cell death after short times of starvation

Keywords: 3-Methyladenine (Pubmed CID 1673); Camptothecin (Pubmed CID 24360); Etoposide (Pubmed CID 36462); 7-Bromoindirubin-3-oxime (Pubmed CID 11846148); Necrostatin-1 (Pubmed CID 282833); Q-VD-OPh (Pubmed CID 11237609); 2-Phenylethynesulfonamide (Pubmed CID 3276

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs

Keywords: 3MA; 3-methyladenine; Baf (or Baf A1); bafilomycin A1; BSA; bovine serum albumin; GABARAP; γ-aminobutyric acid receptor-associated protein; LC3; microtubule-associated protein 1 light chain 3; LDH; lactate dehydrogenase; MEFs; mouse embryonic fibroblasts

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

The role of autophagic degradation in the heart

Keywords: αMHC-Cre+; transgenic mice expressing Cre recombinase under the control of α-myosin heavy chain promoter; Ambra1; activating molecule in Beclin 1-regulated autophagy; AMPK; AMP-activated protein kinase; Atg; autophagy-related; Bcl; B-cell lymphoma; Bnip

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2015 سفارش ترجمه

Endoplasmic reticulum stress-mediated autophagy contributes to bluetongue virus infection via the PERK-eIF2α pathway

Keywords: Bluetongue virus (BTV); Autophagy; Endoplasmic reticulum (ER) stress; PERK-eIF2α pathway; Replication; ER; endoplasmic reticulum; UPR; unfolded protein response; PERK; RNA-dependent protein kinase (PKR)-like endoplasmic reticulum (ER) kinase; eIF2α; the

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2015 سفارش ترجمه

SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK signaling pathway

Keywords: AMPK; AMP-activated protein kinase; AKT; v-akt murine thymoma viral oncogene homolog; Atg; autophagy-related gene; CAY; CAY-10566; CC; compound C; CQ; chloroquine; DAB; 3,3′-diaminobenzidine tetrahydrochloride; ECL; electrochemiluminescence; FBS; fetal

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2015 سفارش ترجمه

Stabilization of microtubular cytoskeleton protects neurons from toxicity of N-terminal fragment of cytosolic prion protein

Keywords: CtmPrP; transmembrane form of prion protein with the C-terminus residing in the lumen of endoplasmic reticulum; cytoPrP; cytosolic prion protein; ER; endoplasmic reticulum; GPI; glycosylphosphatidylinositol; GSK-3; glycogen synthase kinase 3; HBSS; Hank's

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2015 سفارش ترجمه

Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing

Keywords: AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2015 سفارش ترجمه

Chromosome-Associated Protein D3 Promotes Bacterial Clearance in Human Intestinal Epithelial Cells by Repressing Expression of Amino Acid Transporters

Keywords: Condensin; Inflammatory Bowel Disease; Innate Immunity; Dysbiosis; AIEC; adherent-invasive Escherichia coli; BCH; 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid; dCAP-D3; Drosophila chromosome-associated protein-D3; CAP-D3; human chromosome associated p

دانلود رایگان متن کامل مقاله ISI 2460 صفحه سال انتشار : 2015 سفارش ترجمه

The Ca2+ channel TRPML3 specifically interacts with the mammalian ATG8 homologue GATE16 to regulate autophagy

Keywords: TRPML3; GATE16; Autophagy; ATG8; LC3; Split-ubiquitin membrane yeast two-hybrid (MY2H) system;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Age-related disruption of autophagy in dermal fibroblasts modulates extracellular matrix components

Keywords: CMA; chaperone-mediated autophagy; LAMP-2A; lysosome-associated receptor protein type 2A; LC3; microtubule-associated protein 1 light chain 3; leu; leupeptin; MMP-1; matrix metalloproteinase-1; pep; pepstatin A; Autophagy; Autophagosome; Extracellular mat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

LC3B is indispensable for selective autophagy of p62 but not basal autophagy

Keywords: GABARAP; gamma-aminobutyrate receptor-associated protein; GEC-1; glandularepithelial cell protein 1; GATE-16; golgi-associated ATPase enhancer of 16 kDa; ITC; isothermal titration calorimetry; LC3; microtubule-associated protein 1 light chain 3/MAP1LC3;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of p53 increases chemosensitivity to 5-FU in nutrient-deprived hepatocarcinoma cells by suppressing autophagy

Keywords: HCC; hepatocarcinoma; 5FU; 5-fluorouracil; PFT-α; Pifithrin-α; LC3; microtubule associated protein 1 light chain 3; DAPI; 4′,6′-diamidino-2-phenylindole dihydrochloride; GFP-LC3; green fluorescent protein-tagged LC3; PI; propidium iodide; FITC; fluo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy-targeted vaccine of LC3-LpqH DNA and its protective immunity in a murine model of tuberculosis

Keywords: Autophagy; Mycobacterium tuberculosis; LC3; LpqH; Ag85B; Protective immunity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

A calpain-cleaved fragment of β-catenin promotes BCRABL1 + cell survival evoked by autophagy induction in response to imatinib

Keywords: ULK1; unc-51-like kinase; ATG; autophagy-related proteins; FIP200; focal adhesion interacting protein 200; PI3K; class III phosphoinositide 3-kinase; Vps; vacuolar protein sorting; LC3; microtubule-associated protein 1 light chain 3; PE; phosphatidylethan

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

TIA1 interacts with annexin A7 in regulating vascular endothelial cell autophagy

Keywords: HUVEC; human umbilical vein endothelial cell; ANXA7; annexin A7; TIA1; T-cell intracellular antigen-1; ABO; 6-amino-2,3-dihydro-3-hydroxymethyl-1,4-benzoxazine; ApoE−/− mice; apolipoprotein E-deficient mice; LC3; microtubule-associated protein 1 light

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy dysregulation in cell culture and animals models of spinal muscular atrophy

Keywords: SMA; spinal muscular atrophy; SMN; Survival Motor Neuron; LC3; microtubule-associated protein 1A/1B-light chain 3; GFP; green fluorescent protein; RFP; red fluorescent protein; ALS; amyotrophic lateral sclerosis; α-COP; coatomer vesicle protein alpha; Sp

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy in the brain of neonates following hypoxia-ischemia shows sex- and region-specific effects

Keywords: AIF; apoptosis-inducing factor; ANOVA; analysis of variance; Atg; autophagy-related genes; HI; hypoxia-ischemia; LC3; microtubule-associated protein light chain 3; LTR; LysoTracker Red; PBS; Phosphate-buffered saline; PE; phosphatidyl ethanolamine; PND;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy is needed for the growth of pancreatic adenocarcinoma and has a cytoprotective effect against anticancer drugs

Keywords: Pancreatic cancer; Autophagy; Chemotherapy; PANC-1; BxPC-3; 5-Fluorouracil; Gemcitabine; Chloroquine; Wortmannin; LC3

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Perfluorooctane sulfonate blocked autophagy flux and induced lysosome membrane permeabilization in HepG2 cells

Keywords: AO; acridine orange; AVs; autophagic vesicles; LC3; microtubule-associated protein light chain 3; LAMP; lysosomal associated membrane proteins; LDH; lactate dehydrogenase; DAP; death-associated protein; LMP; lysosomal membrane permeabilization; mTor; mamm

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Differential cellular interaction of Sutherlandia frutescens extracts on tumorigenic and non-tumorigenic breast cells

Keywords: BSA; Bovine serum albumin; DMEM; Dulbecco's Modified Eagle's Medium; FCS; Fetal calf serum; LC3; Microtubule-associated protein light chain 3; PBS; Phosphate buffered saline; PlasDIC; Polarization-optical differential interference contrast; PI; Propidium

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Interleukin-1β promotes the LC3-mediated secretory function of osteoclast precursors by stimulating the Ca2+-dependent activation of ERK

Keywords: IL-1β; Cathepsin K; Intracellular Ca2+; LC3; Osteoclast;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Identification and expression analysis of the zebrafish orthologues of the mammalian MAP1LC3 gene family

Keywords: Alzheimer׳s disease; Autophagy; LC3; Hypoxia; Rapamycin; Chloroquine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

PKA phosphorylation of p62/SQSTM1 regulates PB1 domain interaction partner binding

Keywords: aPKC; atypical protein kinase C; cAMP; cyclic AMP-dependent protein kinase; LC3; microtubule-associated protein 1A/B light chain 3; MEK; mitogen-activated protein kinase kinase/ERK kinase; MEKK; MEK kinase; NBR; neighbour of BRCA1 gene 1 protein; NF-κB;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

SQSTM1 mutations - Bridging Paget disease of bone and ALS/FTLD

Keywords: ALS; amyotrophic lateral sclerosis; aPKC; atypical protein kinase C; C9orf72; chromosome 9 open reading frame 72; FTD; frontotemporal dementia; FTLD; frontotemporal lobar degeneration; FUS/TLS; fused in sarcoma/translocated in liposarcoma; GWAS; genome-wi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Nrf2 enhances myocardial clearance of toxic ubiquitinated proteins

Keywords: ANF; atrial natriuretic factor; Ang II; angiotensin II; αMHC; alpha-myosin heavy chain; βMHC; beta-myosin heavy chain; BNP; brain natriuretic factor; BafA1; bafilomycin A1; LC3; microtubule-associated protein 1 light chain 3; NQO1; NAD(P)H:quinone oxido

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanism of 2′,3′-dimethoxyflavanone-induced apoptosis in breast cancer stem cells: Role of ubiquitination of caspase-8 and LC3

Keywords: Apoptosis; Breast cancer stem cells; Caspase-8; 2′,3′-Dimethoxyflavanone; LC3; Ubiquitination

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy in Glomerular Health and Disease

Keywords: Podocyte; kidney; autophagy; mTOR; ATG5; LC3; RAPTOR; FSGS; diabetic nephropathy; glomerulonephritis; lysosomal storage diseases

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Energy adaptive response during parthanatos is enhanced by PD98059 and involves mitochondrial function but not autophagy induction

Keywords: 3AB; 3-aminobenzamide; 7AAD; 7-aminoactinomycin D; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; DPI; diphenyliodonium; DXR; doxorubicin; FACS; fluorescence-activated cell sorting; FCCP; trifluorocarbonylcyanide phenylhydrazone; LC3;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Yessotoxin induces ER-stress followed by autophagic cell death in glioma cells mediated by mTOR and BNIP3

Keywords: YTX; yessotoxin; DE; differentially expressed; UPR; unfolded protein response; ER-stress; endoplasmic reticulum stress; mTOR; mechanistic target of rapamycin (serine/threonine kinase); LC3; microtubule-associated protein 1 light chain 3 alpha; BNIP3; BCL2

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Autophagy in placentas from acidotic newborns: An immunohistochemical study of LC3 expression

Keywords: Autophagy; Placenta; LC3; Neonatal encephalopathy; Acidosis;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

CCCP-Induced LC3 lipidation depends on Atg9 whereas FIP200/Atg13 and Beclin 1/Atg14 are dispensable

Keywords: CCCP; carbonyl cyanide m-chlorophenylhydrazone; CQ; chloroquine; EBSS; earle's balanced salt solution; LC3; microtube-associated protein light chain 3; MEFs; mouse embryonic fibroblasts; UKC; ULK kinase complex; Autophagy; CCCP; Atg9; Beclin 1; FIP200;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Autophagy activation and neuroprotection by progesterone in the G93A-SOD1 transgenic mouse model of amyotrophic lateral sclerosis

Keywords: Steroid hormone; Spinal cord; hSOD1; LC3; ALS;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Autophagy-mediated degradation is necessary for regression of cardiac hypertrophy during ventricular unloading

Keywords: CKO; cardiac-specific Atg5-deficient mice; CTL; control mice; TAC; thoracic transverse aortic constriction; HW; heart weight; LV; left ventricle; LVW; left ventricle weight; IVSd; end-diastolic interventricular septal thickness; LVPWd; end-diastolic left

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Targeted deletion of Atg5 reveals differential roles of autophagy in keratin K5-expressing epithelia

Keywords: GFP; green fluorescence protein; LC3; microtubule-associated protein light chain 3; RT-PCR; reverse-transcription polymerase chain reaction; H&E; hematoxylin and eosin; TUNEL; terminal deoxynucleotidyl transferase dUTP nick end labeling; Autophagy; Kerati

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Induction of cytoprotective autophagy in PC-12 cells by cadmium

Keywords: Cadmium; Autophagy; Apoptosis; PC-12 cells; LC3;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement

Keywords: Ridaifen-B; Autophagy; LC3; Bcl-2; Beclin 1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Relationship between annexin A7 and integrin β4 in autophagy

Keywords: VEC; vascular endothelial cell; ANXA7; Annexin A7; HD; hemidesmosome; ECPC; ethyl1-(3-(4-chlorophenoxy)-2-hydroxypropyl)-3-(4-chlorophenyl)-1H-pyrazole-5-carboxylate; ABO; 6-amino-2, 3-dihydro-3-hydroxymethyl-1, 4-benzoxazine; oxLDL; oxidized low-density

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Substituted 2-hydroxy-N-(arylalkyl)benzamides induce apoptosis in cancer cell lines

Keywords: Diamides; Apoptosis; Cytotoxicity; Cancer; Autophagy; p53; PET; photosynthetic electron transport; CDK; cyclin-dependent kinase; BrdU; 5-bromo-2′-deoxyuridine; SAR; structure-activity relationship; GSK; glycogen synthase kinase; Rb; retinoblastoma pro

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Regulated in DNA damage and development 1 (REDD1) promotes cell survival during serum deprivation by sustaining repression of signaling through the mechanistic target of rapamycin in complex 1 (mTORC1)

Keywords: 4E-BP1; eukaryotic initiation factor 4E binding protein 1; ATF4; activating transcription factor 4; ca; constitutively active; dn; dominant negative; ERK; extracellular signal-related protein kinase; FBS; fetal bovine serum; GCN2; general control non-dere

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Coordinated time-dependent modulation of AMPK/Akt/mTOR signaling and autophagy controls osteogenic differentiation of human mesenchymal stem cells

Keywords: AMPK; adenosine monophosphate-activated protein kinase; BMP2; bone morphogenetic protein 2; hDP-MSC; human dental pulp mesenchymal stem cells; LC3; microtubule-associated protein 1 light-chain 3; mTOR; mammalian target of rapamycin; Runx2; Runt-related tr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

PM2.5-induced oxidative stress triggers autophagy in human lung epithelial A549 cells

Keywords: EC; elemental carbon; DAPI; 4,6-diamido-2-phenylindole hydrochloride; DCF; 2′,7′-dichlorofluorescein; DCFH-DA; 2′,7′-dichlorodihydrofluorescein diacetate; LC3; microtubule-associated proteins light chain 3; LDH; lactate dehydrogenase; NAC; N-acety

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Loss of CB1 receptors leads to decreased cathepsin D levels and accelerated lipofuscin accumulation in the hippocampus

Keywords: Endocannabinoid system; Hippocampus; Oxidative stress; LC3; p62; Autophagy;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Calpain 1 induce lysosomal permeabilization by cleavage of lysosomal associated membrane protein 2

Keywords: AIF; Apoptosis Inducing Factor; ALLN; N-Acetyl-Leu-Leu-Nle-CHO; AP; Alkaline Phosphatase; BCA; Bicinchoninic Acid; BSA; Bovine Serum Albumin; CAD; Caspase Activated DNase; CA; Cornu Ammonis; CMA; chaperon mediated autophagy; DMEM; Dulbecco's Modified Ea

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

PRIMA-1 induces autophagy in cancer cells carrying mutant or wild type p53

Keywords: PRIMA-1; Autophagy; p53; LC3; Electron microscopy;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

The role of elevated autophagy on the synaptic plasticity impairment caused by CdSe/ZnS quantum dots

Keywords: Autophagy; LC3-I/II; QDs; Synaptic plasticity; Synapsin-I; Synapse density; QD; quantum dot; LC3; light chain protein 3; PE; phosphatidylethanolamine; mTOR; mammalian target of rapamycin; LTP; long-term potentiation; I/O; input/output; PPF; paired-pulse f

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntington's disease

Keywords: HD; Huntington's disease; htt; huntingtin; LC3; microtubule-associated protein light 3; mhtt; mutant huntingtin; NBR1; Neighbor of BRCA1 Gene 1; polyQ; polyglutamine; Nrf2; nuclear factor (erythroid-derived 2)-like 2; Xpo-1; exportin-1; Aggregates; Autoph

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Azathioprine desensitizes liver cancer cells to insulin-like growth factor 1 and causes apoptosis when it is combined with bafilomycin A1

Keywords: ERK; extracellular signal-regulated kinase; TSC-2; tuberous sclerosis 2 protein; mTOR; mammalian target of rapamycin; IRS; insulin receptor substrate; PI3K; phosphoinositide-3-kinase; AKT; protein kinase B; MAPK; mitogen-activated protein kinase; FOXO1; f

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Carbamazepine suppresses calpain-mediated autophagy impairment after ischemia/reperfusion in mouse livers

Keywords: MPT; mitochondrial permeability transition; I/R; ischemia/reperfusion; CBZ; carbamazepine; FDA; Food & Drug Administration; Atg; autophagy-related proteins; KRH; Krebs-Ringer-N-2 hydroxyethylpiperazine-N-2 ethanesulfonic acid; PI; propidium iodide; TMRM

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Huang-Lian-Jie-Du-Decotion induced protective autophagy against the injury of cerebral ischemia/reperfusion via MAPK-mTOR signaling pathway

Keywords: HLJDD; Huang-Lian-Jie-Du-Decotion; MCAO; middle cerebral artery occlusion; TTC; 2,3,5-triphenyltetrazolium chloride; HE; hematoxylin-eosin; NO; nitric oxide; MDA; malondialdehyde; GSH; glutathione; GSSG; glutathione disulfide; T-SOD; total superoxide di

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه