Keywords: عامل مرگبار; Zinc; Copper; Lethal factor; Proteases; Metal substitution; Enzyme mechanism;
مقالات ISI عامل مرگبار (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: عامل مرگبار; PA; protective antigen; LF; lethal factor; EF; edema factor; Ï clamp; phenylalanine clamp; MWC; Monod-Wyman-Changeux; CDF; cumulative distribution function; AIC; Akaike information criterion; BB; bilayer buffer; BClB; bilayer chloride buffer; Bacillu
Keywords: عامل مرگبار; PA; protective antigen; LF; lethal factor; EF; edema factor; ÎÏ; membrane potential; α clamp; α helix binding clamp; Ï clamp; phenylalanine clamp; CDF; cumulative distribution function; WT; wild-type; HBS; hydrogen bond surrogate; UBB; universal bila
Keywords: عامل مرگبار; AMC; 7-amino-4-methylcoumarin; CHO; Chinese hamster ovary; ER; endoplasmic reticulum; G; guanidino group; GRAP; Golgi-retained alkaline phosphatase; LF; lethal factor; MMP; matrix metalloproteinases; PA; protective antigen; PC; proprotein convertase; pRTK
Keywords: عامل مرگبار; BAP; benzyl amino purine; BC; before challenge titers; CFU; colony forming units; CT; cholera toxin; DMEM; Dulbecco's modified eagle medium; ELISA; enzyme linked immunosorbent assay; HRP; horseradish peroxidase; IBA; indole-3-butyric acid; i.p.; intraperi
Keywords: عامل مرگبار; Bacillus anthracis; Anthrax; Lethal factor; Botulinum neurotoxin A; Light chain; Zinc metalloprotease; Matrix metalloprotease; Quinoline; Hybrid compound; Desymmetrized;
Validated MALDI-TOF-MS method for anthrax lethal factor provides early diagnosis and evaluation of therapeutics
Keywords: عامل مرگبار; Bacillus anthracis; Anthrax; Bacterial protein toxin; Lethal factor; Enzyme activity; Isotope-dilution mass spectrometry;
Inhibition of anthrax lethal factor by ssDNA aptamers
Keywords: عامل مرگبار; BSA; bovine serum albumin; CD; circular dichroism; DMEM; Dulbecco's Modified Eagle Medium; DMSO; dimethyl sulfoxide; EMSA; electrophoretic mobility shift assay; EF; Edema factor; FBS; fetal bovine serum; GST; Glutathione S-transferase; LF; lethal factor;
Disarmed anthrax toxin delivers antisense oligonucleotides and siRNA with high efficiency and low toxicity
Keywords: عامل مرگبار; ASOs; antisense oligonucleotides; Atx; anthrax toxin; BME; beta-mercaptoethanol; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; E7; early 7; EEA1; early endosomal antigen 1; LFn; Atx lethal factor domain I; GFP; Green fluorescent prote
Recombinant expression and purification of a tumor-targeted toxin in Bacillus anthracis
Keywords: عامل مرگبار; DT389; N-terminal 389 amino acids of diphtheria toxin; DT-TGF; DT389-TGFα; EF; edema factor; LF; lethal factor; LFn; lethal factor N-terminus; LFn-DT-TGF; LFn-TEV-DT389-TGFα; LPS; lipopolysaccharide; PA; protective antigen; TEV; tobacco etch virus
Secretory expression and efficient purification of recombinant anthrax toxin lethal factor with full biological activity in E. coli
Keywords: عامل مرگبار; Bacillus anthracis; Lethal factor; Recombinant protein; Secretory expression; Periplasm; Purification
Antidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chain
Keywords: عامل مرگبار; Anthrax; Lethal factor; Inhibitor; In vitro ADME; X-ray crystallography
Protective effect of Bacillus anthracis surface protein EA1 against anthrax in mice
Keywords: عامل مرگبار; AVA; anthrax vaccine adsorbed; AVP; anthrax vaccine precipitated; EA1; extractable antigen 1; EF; edema factor; ELISA; enzyme-linked immunosorbent assay; i.n.; intranasal; i.p.; intraperitoneal; LF; lethal factor; mAb; monoclonal antibody; PA; protective
The effect of deletion of the edema factor on Bacillus anthracis pathogenicity in guinea pigs and rabbits
Keywords: عامل مرگبار; Bacillus anthracis; Lethal factor; Edema factor; Intranasal instillation; Pathogenicity; Mutagenesis;
Electroporation of a multivalent DNA vaccine cocktail elicits a protective immune response against anthrax and plague
Keywords: عامل مرگبار; Anthrax; Plague; DNA vaccine; Recombinant protein vaccine; Intramuscular electroporation; Immunization; PA; protective antigen; LF; lethal factor; EF; edema factor; pDNA; plasmid deoxyribonucleic acid; BCA; bicinchoninic acid; ELISA; enzyme-linked immunos
Antidotes to anthrax lethal factor intoxication. Part 2: Structural modifications leading to improved in vivo efficacy
Keywords: عامل مرگبار; Anthrax; Lethal factor; Inhibitor; Small molecule
Subsite specificity of anthrax lethal factor and its implications for inhibitor development
Keywords: عامل مرگبار; Bacillus anthracis; Lethal factor; Specificity; Inhibitor
Yeast-hybrid based high-throughput assay for identification of anthrax lethal factor inhibitors
Keywords: عامل مرگبار; LF; lethal factor; PA; protective antigen; LeTx; lethal toxin consisting of PA and LF; DNA-BD; DNA-binding domain; AD; transcription activation domain; cGAL4-LFS; minimal Gal4 transcription factor containing an optimized LF peptide substrate between the c
Lethal factor is not required for Bacillus anthracis virulence in guinea pigs and rabbits
Keywords: عامل مرگبار; Bacillus anthracis; Lethal factor; Edema factor; Intranasal instillation; Pathogenicity; Mutagenesis;
Anthrax vaccination induced anti-lethal factor IgG: Fine specificity and neutralizing capacity
Keywords: عامل مرگبار; Bacillus anthracis; Anthrax; Anthrax vaccine adsorbed; Lethal factor; Protective antigen; Correlate of protection;
A plant based protective antigen [PA(dIV)] vaccine expressed in chloroplasts demonstrates protective immunity in mice against anthrax
Keywords: عامل مرگبار; AP; alkaline phosphatase; AVA; anthrax vaccine adsorbed; BAP; benzyl amino purine; BC; before challenge titers; cfu; colony forming units; CTAB; cetyltrimethyl ammonium bromide; CT; cholera toxin; DMEM; Dulbecco's modified eagle medium; EF; edema factor;
An anthrax subunit vaccine candidate based on protective regions of Bacillus anthracis protective antigen and lethal factor
Keywords: عامل مرگبار; Anthrax; B. anthracis; Vaccine; Lethal factor; Protective antigen; T cell; Protection; Fusion protein
Insilico studies on anthrax lethal factor inhibitors: Pharmacophore modeling and virtual screening approaches towards designing of novel inhibitors for a killer
Keywords: عامل مرگبار; Anthrax; Lethal factor; Pharmacophore; Virtual screening; Bioweapon
Induction of autophagy by anthrax lethal toxin
Keywords: عامل مرگبار; Autophagy; Bacillus anthracis; Anthrax; Lethal factor; Protective antigen; LC3; Autophagosome;
The anthrax lethal factor and its MAPK kinase-specific metalloprotease activity
Keywords: عامل مرگبار; Anthrax; Lethal factor; Metalloprotease; MAPK kinase; Botulinum neurotoxins
Identification and characterization of immunodominant B-cell epitope of the C-terminus of protective antigen of Bacillus anthracis
Keywords: عامل مرگبار; AP; alkaline phosphatase; ELISA; enzyme-linked immuno sorbent assay; FBS; fetal bovine serum; HEPES; N-(2-hydroxyethyl) piperazine-Nâ²-(2-ethane-sulfonic acid) sodium salt; HRP; horse radish peroxidase; ID; immunodominant; LF; lethal factor; MTT; 3-(4, 5
Inhibitors of anthrax lethal factor based upon N-oleoyldopamine
Keywords: عامل مرگبار; Anthrax; Uncompetitive inhibition; Lethal factor; Anti-toxin
Ratio of lethal and edema factors in rabbit systemic anthrax
Keywords: عامل مرگبار; Bacillus anthracis; Lethal factor; Edema factor; Protective antigen; Anthrax infection
Efficient production and characterization of Bacillus anthracis lethal factor and a novel inactive mutant rLFm-Y236F
Keywords: عامل مرگبار; Bacillus anthracis; Lethal factor; Anthrax; Lethal toxin; Protein purification;
In vitro evaluation, biodistribution and scintigraphic imaging in mice of radiolabeled anthrax toxins
Keywords: عامل مرگبار; Anthrax; Protective antigen; Lethal factor; Edema factor; 188-Rhenium; Scintigraphic imaging
The effects of anthrax lethal factor on the macrophage proteome: Potential activity on nitric oxide synthases
Keywords: عامل مرگبار; Lethal factor; Proteome analysis of proteolytic products of in vitro LF assay; Nitric oxide synthase
Binding of N-terminal fragments of anthrax edema factor (EFN) and lethal factor (LFN) to the protective antigen pore
Keywords: عامل مرگبار; Anthrax toxin; Edema factor; Lethal factor; PA channel; N-terminal fragment; Lipid bilayer
Inhibitors of anthrax lethal factor
Keywords: عامل مرگبار; Anthrax; Lethal factor; Inhibitor
Lethal factor of anthrax toxin binds monomeric form of protective antigen
Keywords: عامل مرگبار; Anthrax toxin; Monomers; Lethal factor; Protective antigen
Qualification and performance characteristics of a quantitative enzyme-linked immunosorbent assay for human lgG antibodies to anthrax lethal factor antigen
Keywords: عامل مرگبار; Bioterrorism; Anthrax; Lethal factor; ELISAAP, affinity purified; CV, coefficient of variation; ETx, edema toxin; ELISA, enzyme-linked immunosorbent assay; LF, lethal factor; LTx, lethal toxin; MDC, minimal detectable concentration; PA, protective antigen
A high-throughput screening approach to anthrax lethal factor inhibition
Keywords: عامل مرگبار; Anthrax; Lethal factor; High-throughput screening; Botulinum Neurotoxin
Mechanistic differences between in vitro assays for hydrazone-based small molecule inhibitors of anthrax lethal factor
Keywords: عامل مرگبار; Anthrax; Lethal factor; Inhibitor; Hydrazone
Catalytically inactive anthrax toxin(s) are potential prophylactic agents
Keywords: عامل مرگبار; PA, protective antigen; LF, lethal factor; EF, edema factor; LeTx, lethal toxin; EdTx, edema toxin; Ab, antibody; Ig, immunoglobulin; LPS, lipopolysaccharide; ELISA, enzyme-linked immunosorbent assayEdema factor; Lethal factor; Active site mutants
The discovery of a potent and selective lethal factor inhibitor for adjunct therapy of anthrax infection
Keywords: عامل مرگبار; Anthrax; Lethal factor; Hydroxyamic acid
Evaluation of the ability of N-terminal fragment of lethal factor of Bacillus anthracis for delivery of Mycobacterium T cell antigen ESAT-6 into cytosol of antigen presenting cells to elicit effective cytotoxic T lymphocyte response
Keywords: عامل مرگبار; Fusion; CTL; Cytokines; Lethal factor
Single-step purification of recombinant anthrax lethal factor from periplasm of Escherichia coli
Keywords: عامل مرگبار; Bacillus anthracis; Lethal factor; Recombinant protein; Single-step purification; Periplasm
Development of high-throughput assay of lethal factor using native substrate
Keywords: عامل مرگبار; Anthrax; High-throughput assay; Lethal factor; Native substrate MEK1;
Anthrax lethal toxin enhances cytokine-induced VCAM-1 expression on human endothelial cells
Keywords: عامل مرگبار; Bacillus anthracis; Vasculitis; Adhesion molecules; Endothelium; Lethal factor; RANTES; Tumor necrosis factor-α; Anthrax pathogenesis;
Differential susceptibility of macrophage cell lines to Bacillus anthracis-Vollum 1B
Keywords: عامل مرگبار; BA, Bacillus anthracis; LDH, lactate dehydrogenase; MÏ, macrophage; NR, neutral red; TB, trypan blue; V1B, Vollum 1B; LeTx, lethal toxin; EdTx, edema toxin; Macrophage; Vollum 1B; Anthrax; Toxicity; Lethal factor;
Anthrax lethal toxin represses glucocorticoid receptor (GR) transactivation by inhibiting GR-DNA binding in vivo
Keywords: عامل مرگبار; Glucocorticoid; Receptor; Anthrax; Lethal factor; Lethal toxin; Nuclear hormone receptors; Repression;
Membrane type-1 matrix metalloproteinase (MT1-MMP) protects malignant cells from tumoricidal activity of re-engineered anthrax lethal toxin
Keywords: عامل مرگبار; DMEM; Dulbecco's MEM; FP59; fusion protein 59 (a chimera in which LF residues 1-254 have been fused with the ADP-ribosylation domain III of Pseudomonas exotoxin A); EF; edema factor; LF; lethal factor; lysis buffer; 5Â mM Tris-HCl buffer, pH 8.0, co
Development of an edema factor-mediated cAMP-induction bioassay for detecting antibody-mediated neutralization of anthrax protective antigen
Keywords: عامل مرگبار; CHO; Chinese hamster ovary; EF; edema factor; PA; protective antigen; LF; lethal factor; LeTx; lethal toxin; cps; counts per second; CV; coefficient of variation; IBMX; 3-isobutyl-1-methylxanthine; cAMP; cyclic adenosine monophosphate; PAmAb; monoclonal a
Molecular basis for improved anthrax vaccines
Keywords: عامل مرگبار; Anthrax; Bacillus anthracis; Vaccine; Protective antigen; Lethal toxin; Edema toxin; Ames strain; Sterne strain; Lethal factor; Edema factor; Protective immunity; Recombinant PA; Monoclonal antibody; Genetic immunization; Adjuvants; Epitopes;