Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity
Keywords: کبد X گیرنده; ROR; retinoic acid-related orphan receptor; PXR; pregnane X receptor; LXR; liver X receptor; IBD; inflammatory bowel disease; RA; rheumatoid arthritis; MS; multiple sclerosis;