دانلود مقالات ISI درباره Lloq + ترجمه فارسی

Development and validation of an ELISA method for the quantification of nivolumab in plasma from non-small-cell lung cancer patients

Keywords: ALP; Alkaline Phosphatase; ALT; alanine transaminase; AST; aspartate aminotransferase; BSA; Bovine Serum Albumin; CRP; C-Reactive Protein; CV; Coefficient of Variation; ECOG; Eastern Cooperative Oncology Group; EMA; European Medicines Agency; FDA; Food an

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Is a deuterated internal standard appropriate for the reliable determination of olmesartan in human plasma?

Keywords: CI; confidence interval; EMA; European Medicines Agency; FDA; US Food and Drug Administration; IS; internal standard; LLOQ; lower limit of quantification; OLM; olmesartan; SIL; stable isotopically labelled; Olmesartan; Liquid chromatography/mass spectrome

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Immune responses in DAA treated chronic hepatitis C patients with and without prior RG-101 dosing

Keywords: Chronic hepatitis C; DAA treatment; Immune response; miRNA-122; HCV; hepatitis C virus; IP-10; interferon gamma-induced protein; CHC; chronic hepatitis C; DAAs; direct acting antivirals; SVR; sustained virological response; miR-122; microRNA-122; RAS; res

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Doxorubicin Drug-Eluting Embolic Chemoembolization of Hepatocellular Carcinoma: Study of Midterm Doxorubicin Delivery in Resected Liver Specimens

Keywords: DEE; drug-eluting embolic; FTIR; Fourier transform infrared; HCC; hepatocellular carcinoma; LLOQ; lowest limit of quantification;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Research articleSimultaneous determination and pharmacokinetic study of twelve bioactive compounds in rat plasma after intravenous administration of Xuebijing injection by UHPLC-Q-Orbitrap HRMS

Keywords: UHPLC-Q-Orbitrap HRMS; ultra high performance liquid chromatography -Q exactive hybrid quadrupole-orbitrap high-resolution accurate mass spectrometry; IS; internal standard; HESI; heat electrospray ionization; LLOQ; the lower limit of quantitation; RE; re

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Pharmacokinetic based study on “lagged stimulation” of Curcumae Longae Rhizoma - Piper nigrum couplet in their main active components' metabolism using UPLC-MS-MS

Keywords: Curcumae Longae Rhizoma; Piper nigrum; UHPLC-MS-MS; Lagged stimulation; Pharmacokinetics; TCM; Traditional Chinese Medicine; Cur; curcumin; Pip; piperine; UPLC-MS-MS; ultra-performance liquid chromatography-mass spectrometry; ESI; electrospray ionizatio

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Simultaneous quantification of 25-hydroxyvitamin D3-3-sulfate and 25-hydroxyvitamin D3-3-glucuronide in human serum and plasma using liquid chromatography-tandem mass spectrometry coupled with DAPTAD-derivatization

Keywords: LC-MS/MS; liquid chromatography-tandem mass spectrometry; DAPTAD; 4-(4′-dimethylaminophenyl)-1,2,4-triazoline-3,5-dione; LLE; liquid-liquid extraction; LLOQ; lower limit of quantification; MRM; multiple reaction monitoring; 25-OHD3; 25-hydroxyvita

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

The pharmacokinetics and tissue distribution of coumaroylspinosin in rat: A novel flavone C-glycoside derived from Zizyphi Spinosi Semen

Keywords: AUC; area under the curve; CE; collision energy; CL; clearance rate; ESI; electrospray ionization; IS; internal standard; LLOQ; lower limit of quantification; MRM; multiple reaction monitoring; MRT; mean residence time; QC; quality control; RE; relative e

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Determination of a novel anticancer AMPK activator hernandezine in rat plasma and tissues with a validated UHPLC-MS/MS method: Application to pharmacokinetics and tissue distribution study

Keywords: AUC0-t; area under the peak-time curve from time zero to last sampling time; ESI; electrospray ionization; IS; internal standard; Ke; elimination rate constant; LLOQ; lower limit of quantification; MRM; multiple reaction monitoring; t1/2; biological hal

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Detailed analysis of cortisol, cortisone and their tetrahydro- and allo-tetrahydrometabolites in human urine by LC-MS/MS

Keywords: ACN; acetonitrile; allo-THE; 5α-tetrahydrocortisone, allo-tetrahydrocortisone; alloTHF; 5α-tetrahydrocortisol, allo-tetrahydrocortisol; AME; apparent mineralocorticoid excess; DCM; dichloromethane; E; cortisone; EMA; European Medicines Agency; F; cortis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Development and validation of a UPLC-MS/MS assay for the determination of gemcitabine and its L-carnitine ester derivative in rat plasma and its application in oral pharmacokinetics

Keywords: Gemcitabine; L-carnitine; Prodrug; Pharmacokinetics; UPLC/MS/MS; JDR; 2'-deoxy-2', 2'-difluoro-N-((4-amino-4-oxobutanoyl)oxy)-4-(trimethyl amm-onio) butanoate-cytidine; SPE; solid-phase extraction; LLOQ; lower limit of quantification; PK; pharmacokinetic;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Determination of prodrug treosulfan and its biologically active monoepoxide in rat plasma, liver, lungs, kidneys, muscle, and brain by HPLC-ESI-MS/MS method

Keywords: CV; coefficient of variation; EMA; European Medicines Agency; ESI; electrospray ionization; HSCT; hematopoietic stem cell transplantation; IS; internal standard; LLOQ; lower limit of quantitation; MF; matrix effect; RID; refractive index detector; r.t.; r

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

A new fluorescence-based method for characterizing in vitro aerosol exposure systems

Keywords: CMAG; condensation monodisperse aerosol generator; DSF; disodium fluorescein; VC24/48; Vitrocell® 24/48 aerosol exposure system; PBS; phosphate buffered saline; PM; particulate matter; GVP; gas-vapor phase; APS; aerodynamic particle sizer; e-cigarettes;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Validation of a new method by nano-liquid chromatography on chip tandem mass spectrometry for combined quantitation of C3f and the V65 vitronectin fragment as biomarkers of diagnosis and severity of osteoarthritis

Keywords: OA; osteoarthritis; 2-DE; two-dimensional electrophoresis; SELDI-TOF-MS; surface enhanced laser desorption/ionization-time of flight mass spectrometry; MALDI-TOF; matrix-assisted laser desorption/ ionization-time of flight; K&L; Kellgren and Lawrence; HV;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Are Idiopathic Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Related to Drugs in Food? The Example of Phenylbutazone

Keywords: LLOQ; lower limit of quantification; NSAID; nonsteroidal anti-inflammatory drug; OPB; oxyphenbutazone; PBZ; phenylbutazone; SBZ; suxibuzone; SJS; Stevens-Johnson syndrome; TEN; toxic epidermal necrolysis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Sex-specific and inter-individual differences in biomarkers of selenium status identified by a calibrated ELISA for selenoprotein P

Keywords: Ab; antibody; CV; coefficient of variation; ELISA; enzyme-linked immunosorbent assay; GPX3; glutathione peroxidase 3; LLOQ; lower limit of quantification; LOD; limit of detection; LRP; lipoprotein receptor-related protein; mAb; monoclonal antibody; pAb; p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Roles of Angiotensin Peptides and Recombinant Human ACE2 in Heart Failure

Keywords: angiotensin II; angiotensin-(1-7); chymase; dilated cardiomyopathy; renin-angiotensin system; ACE; angiotensin-converting enzyme; ACEI; angiotensin-converting enzyme inhibitor; AHF; acute heart failure; Ang I; angiotensin-(1-10); Ang II; angiotensin-(

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Inter-laboratory skin distribution study of 4-n-butyl resorcinol: The importance of liquid chromatography/mass spectrometry (HPLC-MS/MS) bioanalytical validation

Keywords: ACN; acetonitrile; AD; applied dose; APCI; atmospheric pressure chemical ionization; De; dermis; Ep; epidermis; ER; extraction recovery; ESI; electrospray ionization; FA; formic acid; IS; internal standard; LC; liquid chromatography; LLOQ; lower limit of

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Pharmacokinetics, excretion balance, and tissue distribution of [14C]-labeled glycolipids and long chain fatty acids from Dacryopinax spathularia in rats

Keywords: Jelly mushroom glycolipids; Natural preservative; Bioavailability; Long chain fatty acids; AUC; area under the concentration versus time curve; BLQ; below the quantitation limit; CMC; carboxymethylcellulose; Cmax; peak concentration; DN; dose normalized;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Efficacy of Ledipasvir Plus Sofosbuvir for 8 or 12 Weeks in Patients With Hepatitis C Virus Genotype 2 Infection

Keywords: Antiviral agents; Direct-acting antivirals; Polymerase inhibitor; NS5A inhibitor; EC50; half-maximal effective concentration; HCV; hepatitis C virus; LLOQ; lower limit of quantification; RASs; resistance-associated substitutions; SVR; sustained virologica

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

A simple and rapid UHPLC-MS/MS method for the quantitation of the dual aurora kinase A/B inhibitor SCH-1473759 in murine plasma

Keywords: UHPLC; ultra-high performance liquid chromatography; MS; mass spectrometry; MS/MS; tandem mass spectrometry; QC; quality control; LLOQ; lower limit of quantification; ACN; acetonitrile; %DEV; percent deviation from the nominal value; WRP; within-run preci

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Simultaneous quantification of estrogens, their precursors and conjugated metabolites in human breast cancer cells by LC-HRMS without derivatization

Keywords: 3β-HSD; 3β-hydroxysteroiddehydrogenase; 17β-HSD; 17β-hydroxysteroiddehydrogenase; AD; androstenedione; DHEA; dehydroepiandrosterone; DHEA-S; dehydroepiandrosterone-3-sulfate; DMEM; Dulbecco's Modified Eagle Medium F-12; DMSO; dimethylsulfoxide; DPBS;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

An LC-MS/MS method for simultaneous determination of nine steroidal saponins from Paris polyphylla var. in rat plasma and its application to pharmacokinetic study

Keywords: UPLC; ultra-performance liquid chromatography; I.S.; internal standard; AUC; area under the curve; QC; quality control; LLOQ; lower limit of quantification; MPA; mobile phase A; MPB; mobile phase B; Paris polyphylla; Steroidal saponins; Pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Ketamine metabolites with antidepressant effects: Fast, economical, and eco-friendly enantioselective separation based on supercritical-fluid chromatography (SFC) and single quadrupole MS detection

Keywords: CYP; cytochrome P450; DHK; dehydronorketamine; KET; ketamine; NK; norketamine; NK-d4; norketamine-d4; HNK; hydroxynorketamine; SFC-MS; supercritical-fluid chromatography single quadrupole mass spectrometry; LLOQ; lower limit of quantification; LOD; limit

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

An UPLC-MS/MS method for the quantification of BRAF inhibitors (vemurafenib, dabrafenib) and MEK inhibitors (cobimetinib, trametinib, binimetinib) in human plasma. Application to treated melanoma patients

Keywords: BRAFi; BRAF inhibitors; MEKi; MEK inhibitors; Cmin; Trough concentration; CV; Coefficient of variation; EMA; European Medical Agency; ESI; Electrospray ionization; LC-UV; Liquid chromatography combined to UV detection; LLOQ; Low limit of quantification; M

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Method validation and nanoparticle characterization assays for an innovative amphothericin B formulation to reach increased stability and safety in infectious diseases

Keywords: DDS; drug delivery system; NLC; nanostructured lipid carrier; Blank NLC; unloaded nanostructured lipid carrier; AmB; amphotericin B; NLC-AmB; amphotericin B loaded nanostructured lipid carrier; DLS; dinamic light scattering; PdI; polydispersivity index; A

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Perspectives on using a multiplex human kidney safety biomarker panel to detect cisplatin-induced tubular toxicity in male and female Cynomolgus monkeys

Keywords: AKI; acute kidney injury; ALB; albumin; α1M; alpha 1 microglobulin; αGST; alpha glutathione S-transferase; β2M; beta 2 microglobulin; BUN; blood urea nitrogen; CALB; calbindin D28k; CLU; clusterin; Cr; creatinine; CYS C; cystatin C; DIKI; drug-induced

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Andrographolide-loaded nanoparticles for brain delivery: Formulation, characterisation and in vitro permeability using hCMEC/D3 cell line

Keywords: AG; andrographolide; ATM; adsorptive-mediated transcytosis; BBB; blood-brain barrier; BSA; bovine serum albumin; CNS; central nervous system; DLS; Dynamic Light Scattering; DMSO; dimethyl sulfoxide; ECA; ethylcyanoacrylate; EE; encapsulation efficiency; E

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

PLGA-PEG-PLGA triblock copolymeric micelles as oral drug delivery system: In vitro drug release and in vivo pharmacokinetics assessment

Keywords: UA; Ursolic acid; US597; a derivatives of UA; US597@micelles; the formulation of PLGA-PEG-PLGA tri-block micelles loaded with US597; PAMAM; polyamidoamine; SD rats; Sprague-Dawley rats; UPLC/MS/MS; Ultra-performance liquid chromatography tandem mass-spe

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

A simple dilute and shoot approach incorporated with pentafluorophenyl (PFP) column based LC-MS/MS assay for the simultaneous determination of trimethylamine N-oxide and trimethylamine in spot urine samples with high throughput

Keywords: PFP; pentafluorophenyl; TMAO; trimethylamine N-oxide; TMA; trimethylamine; FMO3; flavin-containing monooxygenase 3; TMAU; trimethylaminuria; 1H NMR; proton nuclear magnetic resonance spectrometry; GC; gas chromatography; MS; mass spectrometer; LC; liquid

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds

Keywords: Acr-dG; 1,N2-propanodeoxyguanosine; AGEs; advanced glycation end-product; ALEs; advanced lipoxidation end product; ApoB100; apolipoprotein B100; ApoE; apolipoprotein E; ARP; aldehyde reactive probe; AspN; endoproteinase AspN (flavastacin); βLG; β-lactog

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids

Keywords: DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; EDCs; endocrine disrupting chemicals; LC-MS; liquid chromatography-mass spectrometry; LOD; limit of detection; LLOQ; lower limit of quantification; MTT; 3-(4,5-dimethylthiazol-2-yl)-2

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه

Immunogenicity, safety, and tolerability of the meningococcal serogroup B bivalent rLP2086 vaccine in adult laboratory workers

Keywords: Neisseria meningitidis; Serogroup B; Vaccine; Meningococcal disease; Bivalent rLP2086; Laboratory worker; ACIP; Advisory Committee on Immunization Practices; AE; adverse event; CI; confidence interval; fHBP; factor H binding protein; GMT; geometric mean t

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Pharmacokinetic profile of cefbuperazone in healthy Chinese volunteers after single and multiple drip intravenous infusion by HPLC-MS/MS

Keywords: IS; internal standard; LLOQ; lower limit of quantification; ULOQ; upper limit of quantification; LQC; low quality control; HQC; high quality control; RSD; relative standard deviation; Cefbuperazone; HPLC-MS/MS; Pharmacokinetic; Excretion;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Development and validation of ultrafast LC-MS/MS method for quantification of anti-influenza agent camphecene in whole rat blood using dried blood spots and its application to pharmacokinetic studies

Keywords: DBS; dried blood spot; CV; coefficient of variation; EMA; European medicinal agency; FDA; food and drug administration; IS; internal standard; LC-MS/MS; liquid chromatography coupled with tandem mass-spectrometry; LLOQ; lowest limit of quantitation; LOD

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Simultaneous determination of clofarabine and cytarabine in human plasma by LC-MS/MS

Keywords: AML; acute myeloid leukemia; ALL; acute lymphoid leukemia; CFB; clofarabine; CLARA; chemotherapy regimen with clofarabine 40 mg/m2 and cytarabine 1000 mg/m2; CTB; cytarabine; ESI; electrospray ionisation; HSCT; hematopoietic stem cell transplantation; I

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

A highly sensitive LC-MS/MS method for determination of ketoconazole in human plasma: Application to a clinical study of the exposure to ketoconazole in patients after topical administration

Keywords: LLOQ; lower limit of quantification; IS; internal standard; QC; quality control; LQC; low QC; MQC; medium QC; HQC; high QC; MRM; multiple reaction monitoring; RE; relative error; RSD; relative standard deviation; LC-MS/MS; Ketoconazole; Systemic exposur

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Liquid chromatography-tandem mass spectrometric assay for ponatinib and N-desmethyl ponatinib in mouse plasma

Keywords: ALL; acute lymphoblastic leukemia; BCR-ABL; breakpoint cluster region-Abelson murine leukemia viral oncogene homolog; CML; chronic myeloid leukemia; CYP3A4; cytochrome P450 3A4; DMP; N-desmethyl ponatinib; ESI; electrospray Ionization; FVB; friend leukemi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Simple and validated UHPLC-MS/MS analysis of nimodipine in plasma and cerebrospinal fluid of patients with subarachnoid haemorrhage

Keywords: NIM; nimodipine; LCS; lacosamide; I.S.; internal standard; SAH; aneurysmal subarachnoid haemorrhage; UHPLC; MS/MS ultra high performance liquid chromatography-tandem mass spectrometry; LLE; liquid-liquid extraction; CSF; cerebrospinal fluid; aCSF; artific

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Development and validation of a sensitive UHPLC-MS/MS method for quantitation of prucalopride in rat plasma and its application to pharmacokinetics study

Keywords: UHPLC-MS/MS; ultra high performance liquid chromatography with tandem mass spectrometry; IS; internal standard; ESI; electrospray ionization; LLOQ; the lower limit of quantitation; RE; relative error; RSD; relative standard deviation; CE; collision ener

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Ultrapressure liquid chromatography-tandem mass spectrometry assay using atmospheric pressure photoionization (UPLC-APPI-MS/MS) for quantification of 4-methoxydiphenylmethane in pharmacokinetic evaluation

Keywords: 4-MDM; 4-methoxydiphenylmethane; ACN; acetonitrile; APPI; atmospheric pressure photoionization; BCS; biopharmaceutical classification system; CAD; collision activated dissociation; CE; collision energy; COPD; chronic obstructive pulmonary disease; CEP; co

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Simultaneous quantification of PGI2 and TXA2 metabolites in plasma and urine in NO-deficient mice by a novel UHPLC/MS/MS method

Keywords: PGI2; prostacyclin; TXA2; thromboxane A2; IP; PGI receptor; TP; TX receptor; PLA2; phospholipase A2; PGIS; prostacyclin synthase; TXS; thromboxane A synthase; UHPLC/MS/MS; ultra high-performance liquid chromatography coupled to mass spectrometry; TXB2; th

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Multicentre experience using daclatasvir and sofosbuvir to treat hepatitis C recurrence - The ANRS CUPILT study

Keywords: AE; adverse events; DAAs; direct-acting antiviral agents; DCV; daclatasvir; EOT; end of treatment; GFR; glomerular filtration rate; HCV; hepatitis C virus; HIV; human immunodeficiency virus; IMS; immunosuppressive; LLOQ; lower limit of quantification; LT;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

LC-MS/MS method for quantitation of seven biomarkers in human plasma for the assessment of insulin resistance and impaired glucose tolerance

Keywords: FPG; fasting plasma glucose; IR; insulin resistance; IGT; impaired glucose tolerance; 2-HB; 2-hydroxybutyrate; 3-HB; 3-hydroxybutyrate; 4-MOP; 4-methyl-2-oxopentanoic acid; LGPC; 1-linoleoyl-2-hydroxy-sn-glycero-3-phosphocholine; PFPA; perfluoropentanoic

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Liquid chromatographyâ¿¿tandem mass spectrometric assay for therapeutic drug monitoring of the B-Raf inhibitor encorafenib, the EGFR inhibitors afatinib, erlotinib and gefitinib and the Oâ¿¿desmethyl metabolites of erlotinib and gefitinib in human plasma

Keywords: EGFR; epidermal growth factor receptor; IS; internal standard; LCâ¿¿MS/MS; liquid chromatographyâ¿¿tandem mass spectrometry; LLOQ; lower limit of quantification; SRM; selected reaction monitoring; QC; quality control; Afatinib; Erlotinib; Gefitinib; Encor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Aptima HIV-1 Quant Dx-A fully automated assay for both diagnosis and quantification of HIV-1

Keywords: Aptima; Aptima HIV-1 Quant Dx Assay; VL; viral load; CAP/CTM; COBAS® AmpliPrep/COBAS® TaqMan® HIV-1 Test v2.0; Abbott RT; Abbott RealTime HIV-1 Assay; Procleix; Procleix® Ultrio Elite™ discriminatory assay; LOD; limit of detection; LOQ; limit of qua

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleDaclatasvir plus simeprevir with or without ribavirin for the treatment of chronic hepatitis C virus genotype 1 infection

Keywords: HCV; hepatitis C virus; SMV; simeprevir; PegIFN; peginterferon; RBV; ribavirin; DCV; daclatasvir; ASV; asuneprevir; SVR; sustained virologic response; LLOQ; lower limit of quantitation; AE; adverse event; SVR12; sustained virologic response at posttreatme

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Liquid chromatography-tandem mass spectrometry method for the determination of vitamin K homologues in human milk after overnight cold saponification

Keywords: CID; collision induced dissociation;; CV; coefficient of variation; FDA; Food and Drug Administration; IS; internal standard; K1; phylloquinone; K1-d7; phylloquinone-d7; LC-F; liquid chromatography with fluorescence detection; HPLC-MS/MS; high performan

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Validation of UHPLC-MS/MS methods for the determination of kaempferol and its metabolite 4-hydroxyphenyl acetic acid, and application to in vitro blood-brain barrier and intestinal drug permeability studies

Keywords: 4-HPAA; 4-hydroxyphenyl acetic acid; ACN; acetonitrile; BSA; bovine serum albumin; Cal; calibrator; CCl; cell layer capacitance; CNS; central nervous system; CV%; coefficient of variation; CPT-cAMP; 8-(4-chlorophenylthio)-adenosine-3′,5′-cyclic monoph

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Deglycosylation and absorption of marein, flavanomarein and taxifolin-7-O-β-D-glucopyranoside from capitula of Coreopsis tinctoria in rats and humans

Keywords: Coreopsis tinctoria; Flavonoid glycoside; Flavonoid aglycone; Pharmacokinetic profile; Deglycosylation; TDG; taxifolin-7-O-β-D-glucopyranoside; CCT; the capitula of Coreopsis tinctoria; CCTE; the extract of CCT; GIT; gastrointestinal tracts; AUC; the are

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه