دانلود مقالات ISI درباره Lloq + ترجمه فارسی

بررسی سیستماتیک پیشرفت های اخیر در فارماکوکینتیک چهار دارو کلاسیک چینی که برای درمان بیماری های مغزی و مغزی استفاده می شود

Systematic review of recent advances in pharmacokinetics of four classical Chinese medicines used for the treatment of cerebrovascular disease

Keywords: BBB; blood-brain barrier; CAD; Charged Aerosol Detector; CM; chitosan-microsphere; CP; compritol; CTS; cryptotanshinone; DGLC; Double gradient liquid chromatograph; DH-Ppt; dehydrogynated protopanaxatriol; DSS; danshensu; F; bioavailability; FA; ferulic

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2013 سفارش ترجمه

Benzotriazoles, benzothiazoles and trace elements in an urban road setting in Trondheim, Norway: Re-visiting the chemical markers of traffic pollution

Keywords: BTHs; benzothiazoles; 2‑S‑BTH; 2‑mercaptobenzothiazole; BTH; benzothiazole; 2‑OH‑BTH; 2‑hydroxy‑benzothiazole; 2‑M‑BTH; 2‑morpholin‑4‑yl‑benzothiazole; 2‑Me‑S‑BTH; 2‑methylthio‑benzothiazole; 2‑ABTH; 2‑aminobenzothi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2019 سفارش ترجمه

A validated LC-MS/MS method for simultaneous determination of linagliptin and metformin in spiked human plasma coupled with solid phase extraction: Application to a pharmacokinetic study in healthy volunteers

Keywords: ALG; alogliptin; AUC0-t and AUC0-∞; the areas under the plasma concentration-time curve; Cmax; maximum plasma concentration; DPP-IV; dipeptidyl peptidase; ER; extraction recovery; GIP; glucose-dependent insulinotropic polypeptide; GLP 1; glucagon-

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2019 سفارش ترجمه

Labeling nitrogen species with the stable isotope 15N for their measurement by separative methods coupled with mass spectrometry: A review

Keywords: NO; Nitric oxide; eNOS; endothelial nitric oxide synthase; nNOS; neuronal NO synthases; iNOS; inducible NO synthase; CVDs; cardiovascular diseases; HbSNO; S-nitrosohemoglobin; GSNO; S-nitrosoglutathione; HbFeNO; iron nitrosylhemoglobin; SNALB; S-nitrosoal

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2019 سفارش ترجمه

Bioanalytical assay for the quantification of the ALK inhibitor lorlatinib in mouse plasma using liquid chromatography-tandem mass spectrometry

Keywords: ALK; anaplastic lymphoma kinase; EMA; European Medicines Agency; EML4; echinoderm microtubule-associated protein-like 4; ESI; electro spray ionization; FDA; Food and Drug Administration; IS; internal standard; LC-MS/MS; liquid chromatography-tandem mass s

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Evaluation of a one-step sample preparation protocol for analysis of total serum testosterone by LC-MS/MS

Keywords: 4-dione; androstenedione; 5-diol; androst-5-ene-3β,17β-diol; Cl-butane; 1-chlorobutane; DHEA; dehydroepiandrosterone; DHT; dihydrotestosterone; Endo HQC; endogenous high quality control; Endo LQC; endogenous low quality control; Endo MQC; endogenous med

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Quantitative analysis of the cyclic peptide GG-8-6 in rat plasma using LC-MS/MS and its application to a pharmacokinetic study

Keywords: LC-MS/MS; liquid chromatographic method with tandem mass spectrometric detection; HCC; hepatocellular carcinoma; GG-8-6; cyclo-(Val1-Leu2-Pro3-Ile4-Leu5-Leu6-Leu7-Val8-Leu9); UV; ultraviolet; IS; internal standard; A6; cyclo-(Val1-Leu2-Pro3-Ala4-Leu5-Leu6

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Quantitative determination of cyclic phosphatidic acid and its carba analog in mouse organs and plasma using LC-MS/MS

Keywords: 2ccPA; 2-carba-cyclic phosphatidic acid; ATX; autotaxin; BSA; bovine serum albumin; CID; collision-induced dissociation; CNS; central nervous system; cPA; cyclic phosphatidic acid; CV; coefficient of variation; EDTA-Na2; ethylenediaminetetraacetic acid di

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Rapid analysis of neomycin in cochlear perilymph of guinea pigs using disposable SPE cartridges and high performance liquid chromatography-tandem mass spectrometry

Keywords: Heptafluorobutyric acid; HFBA; Round window membrane; RWM; auditory brainstem response; ABR; Multi Reaction Monitor; MRM; Coefficient of Variation; CV; limit of detection; LOD; lower limit of quantitation; LLOQ; quality control; QC; Neomycin; Perilymph; R

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Analysis by LC-MS/MS of endogenous steroids from human serum, plasma, endometrium and endometriotic tissue

Keywords: A; aldosterone; A4; androstenedione; B; corticosterone; E; cortisone; E1; estrone; E2; estradiol; F; cortisol; DHEA; dehydroepiandrosterone; DHT; dihydrotestosterone; P4; progesterone; P5; pregnenolone; S; 11-deoxycortisol; T; testosterone; 17OHP4; 17a-hy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Simultaneous determination of five bioactive components of Gancao in rat plasma by UHPLC-MS/MS and its application to comparative pharmacokinetic study of incompatible herb pair Gansui-Gancao and Gansuibanxia Decoction

Keywords: TCM; Traditional Chinese Medicine; QC; quality control; LLOQ; lower limit of quantification; IS; internal standard; RE; relative error; RSD; relative standard deviation; PPT; protein precipitation; LLE; liquid-liquid extraction; GC; Gancao; GS-GC; Gansui-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Evaluation of a novel micro-sampling device, Mitra™, in comparison to dried blood spots, for analysis of praziquantel in Schistosoma haematobium-infected children in rural Côte d'Ivoire

Keywords: Cmax; maximal blood concentration; Tmax; time needed to reach maximal blood concentration; T1/2; half life of the drug; AUC; area under the concentration-time curve; DBS; dried blood spots; PZQ; praziquantel; PK; pharmacokinetics; SAC; school-aged childre

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

A fully validated liquid chromatography-mass spectrometry method for the quantification of the soluble receptor of advanced glycation end-products (sRAGE) in serum using immunopurification in a 96-well plate format

Keywords: BSA; bovine serum albumin; CML-BSA; Nε-(carboxymethyl)lysine-modified bovine serum albumin; COPD; chronic obstructive pulmonary disease; CV; coefficient of variation; EMA; European Medicines Agency; ELISA; enzyme-linked immunosorbent assay; FDA; Food and

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Quantitative analysis of dextran in rat plasma using Q-Orbitrap mass spectrometry based on all ion fragmentation strategy

Keywords: DEX; dextran; ISCID; in-source collision-induced dissociation; AIF; all ion fragmentation; SEC; size exclusion chromatography; IS; internal standard; NCE; normalized collision energy; QC; quality control; LLOQ; the lower limit of quantification; MRM; mult

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

A novel method for quantitation of acylglycines in human dried blood spots by UPLC-tandem mass spectrometry

Keywords: Newborn screening; Inborn errors of metabolism; Tandem mass spectrometry; 2MBG; 2-methylbutyrylglycine; 3MCC; 3-methylcrotonyl-CoA carboxylase deficiency; 3MCG; 3-methylcrotonylglycine; AG; acetylglycine; BG; butyrylglycine; BKTD; beta ketothiolase defici

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Determination of four Alternaria alternata mycotoxins by QuEChERS approach coupled with liquid chromatography-tandem mass spectrometry in tomato-based and fruit-based products

Keywords: ACN; acetonitrile; AME; alternariol monomethyl ether; AOH; alternariol; APCI; atmospheric pressure chemical ionisation; CAD; collision activated dissociation; CE; collision energy; CEP; collision cell entrance potential; CUR; curtain gas; CXP; collision c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Extractability-mediated stability bias and hematocrit impact: High extraction recovery is critical to feasibility of volumetric adsorptive microsampling (VAMS) in regulated bioanalysis

Keywords: VAMS; volumetric absorptive microsampling; Ht; hematocrit; LLE; liquid-liquid extraction; GLP; good laboratory practice; LC-MS/MS; liquid chromatography coupled with triple quadrupole mass spectrometry; LLOQ; lower limit of quantification; ULOQ; upper

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Plasma pharmacokinetics and cerebral nuclei distribution of major constituents of Psoraleae fructus in rats after oral administration

Keywords: Psoraleae fructus; Pharmacokinetics; Cerebral nuclei distribution; Coumarins; Prenylflavonoids; LC-MS/MS; ACN; acetonitrile; AUC; area under curve; Aβ42; β-amyloid 42; CE; collision energy; Cmax; maximum drug concentration; CMC-Na; carboxymethyl cellulo

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Cellulose-based amorphous solid dispersions enhance rifapentine delivery characteristics in vitro

Keywords: Rifapentine (PubChem CID: 6323497); Rifampicin (PubChem CID: 5458213); 3-Formylrifamycin (PubChem CID: 6438444); Hydroxypropylmethylcellulose acetate succinate (PubChem CID: 121950); ASD; amorphous solid dispersion; AUC; area under the curve; CASub; cellu

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Efficacy of Glecaprevir/Pibrentasvir for 8 or 12 Weeks in Patients With Hepatitis C Virus Genotype 2, 4, 5, or 6 Infection Without Cirrhosis

Keywords: Direct-acting Antiviral; DAA; Short-duration; Pangenotypic; ALT; alanine aminotransferase; CI; confidence interval; DAA; direct-acting antiviral; G/P; glecaprevir/pibrentasvir; HCV; hepatitis C virus; IFN; interferon; ITT; intention-to-treat; LLOQ; lower

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Clinical data supporting a 2-dose schedule of MenB-FHbp, a bivalent meningococcal serogroup B vaccine, in adolescents and young adults

Keywords: ACIP; Advisory Committee on Immunization Practices; EMA; European Medicines Agency; FDA; US Food and Drug Administration; FHbp; factor H binding protein; GMT; geometric mean titer; HPV; human papillomavirus; hSBA; serum bactericidal assay using human comp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Effective phospholipids removing microelution-solid phase extraction LC-MS/MS method for simultaneous plasma quantification of aripiprazole and dehydro-aripiprazole: Application to human pharmacokinetic studies

Keywords: ARI; aripiprazole; AUC; area under curve; CAL; calibration standard; CID; collision-induced dissociation; Cmax; maximum plasma concentration; CV; coefficient of variation; CYP; cytochrome P450; DAD; diode array detection; DARI; dehydro-aripiprazole; EDTA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Measurement of apixaban, dabigatran, edoxaban and rivaroxaban in human plasma using automated online solid-phase extraction combined with ultra-performance liquid chromatography-tandem mass spectrometry and its comparison with coagulation assays

Keywords: aPTT; activated partial thromboplastin time; BEH; bridged ethyl hybrid; CV; coefficient of variation; DOACs; direct oral anticoagulants; DTI; direct thrombin inhibitor(s); IS; internal standard; MRM; multiple reaction monitoring mode; MS/MS; tandem mass s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Microdialysis combined with RRLC-MS/MS for the pharmacokinetics of two major alkaloids of Bi qi capsule and the potential roles of P-gp and BCRP on their penetration

Keywords: BQC; Bi qi capsule; BBB; blood-brain barrier; RRLC-MS/MS; rapid resolution liquid chromatography -tandem mass spectrometry; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; CNS; central nervous system; CSF; cerebrospinal fluid; LLOQ; lower li

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

A new cause of false positive voriconazole levels: Watch your collection tubes!

Keywords: TDM; Therapeutic drug monitoring; VOR; Voriconazole; HPLC-UV; High-performance liquid chromatography with ultraviolet detector; FDA; Food and drug administration; EMEA; European Medicines Agency; PRE; Percentage relative error; LLOQ; Lower limit of quanti

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Determination of 12 commonly found compounds in DUID cases in whole blood using fully automated supported liquid extraction and UHPLC-MS/MS

Keywords: DUID; driving under influence of drugs; UHPLC-MS/MS; ultra high performance liquid chromatography-tandem mass spectrometry; SLE; supported liquid extraction; IS; internal standard; QC; quality control; ESI; electrospray ionization; R2; the coefficient of

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

High throughput routine determination of 17 tyrosine kinase inhibitors by LC-MS/MS

Keywords: ALL; Acute Lymphoid Leukemia; CML; Chronic Myeloid Leukaemia; CV; Coefficient of Variation; EGFR; Endothelial derived growth factor Receptor; EMA; European Medicines Agency; ER; Extraction Recovery; FDA; Food and Drug Administration; GIST; Gastro Intestin

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Description of analytical method and clinical utility of measuring serum 7-alpha-hydroxy-4-cholesten-3-one (7aC4) by mass spectrometry

Keywords: BAD; bile acid diarrhea; 7aC4; 7-alpha-hydroxy-4-cholesten-3-one; CV; coefficient of variation; IBS; irritable bowel syndrome; LC-MS/MS; liquid chromatography, tandem mass spectrometry; LLOD; lower limit of detection; LLOQ; lower limit of quantitation; 75

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Concentrations of cisplatin and doxorubicin in ascites and peritoneal tumor nodules before and after pressurized intraperitoneal aerosol chemotherapy (PIPAC) in patients with peritoneal metastasis

Keywords: Peritoneal carcinomatosis; Drug uptake; Intraabdominal chemotherapy; High pressure; Ascites; Toxicity; PIPAC; pressurized intraperitoneal aerosol chemotherapy; PC; peritoneal carcinomatosis; IPC; intraperitoneal chemotherapy; DNA; deoxyribonucleic acid; P

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

A rapid, simple, and high-throughput UPLC-MS/MS method for simultaneous determination of bioactive constituents in Salvia miltiorrhiza with positive/negative ionization switching

Keywords: CV; coefficient of variance; ESI; electrospray ionization; LC; liquid chromatography; LOQ; limit of quantification; LOD; limit of detection; LLOQ; lower limit of quantification; MRM; multiple reaction monitoring; MS; mass spectrometer; MS/MS; tandem mass

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of Baoyuan decoction, a traditional Chinese medicine formula, on the activities and mRNA expression of seven CYP isozymes in rats

Keywords: BYD; Baoyuan decoction; TCM; traditional Chinese medicine; CYP; cytochrome P450; HDI; herb-drug interaction; IS; internal standard; RT-PCR; real-time reverse transcription-polymerase chain reaction; QC; quality control; ESI; electrospray ionization; RSD;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Comparative pharmacokinetics of six coumarins in normal and breast cancer bone-metastatic mice after oral administration of Wenshen Zhuanggu Formula

Keywords: WSZG; Wenshen Zhuanggu formula; LC-MS/MS; liquid chromatography tandem mass spectrometry; TCM; traditional Chinese medicine; DMEM; Dulbecco's Modified Eagle's Medium; IS; internal standard; BLI; bioluminescent imaging; HE; hematoxylin and eosin; ZnSO4; Zi

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Confirmation of Luteinizing Hormone (LH) in Living Human Vitreous and the Effect of LH Receptor Reduction on Murine Electroretinogram

Keywords: BSA; bovine serum albumin; ECL; electrochemiluminescence; ERG; electroretinography; hCG; human chorionic gonadotropin; LH; luteinizing hormone; LHR; luteinizing hormone receptor; Lhrko+/−; heterozygous luteinizing hormone receptor knock out; LLOQ; lower

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the EGFR inhibitors afatinib, erlotinib and osimertinib, the ALK inhibitor crizotinib and the VEGFR inhibitor nintedanib in human plasma from non-small cell lung canc

Keywords: AFAT; afatinib; ALK; anaplastic lymphoma kinase; CRIZ; crizotinib; CS; calibration standard; CV; coefficient of variation; DMSO; dimethylsulfoxide; EGFR; epidermal growth factor receptor; ERLO; erlotinib; IQC; internal quality control; IS; internal standa

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Rapid determination of 3′, 4′-dimethoxy flavonol-3-β-d-glucopyranoside in rat plasma by LC-MS/MS method followed by protein precipitation

Keywords: LC-MS/MS; liquid chromatography/tandem mass spectrometry; LLOQ; lower limit of quantification; IS; internal standard; QC; quality control; DF3G; 3′,4′-dimethoxy flavonol-3-β-d-glucopyranoside; HPLC; high performance liquid chromatography; SD; standar

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

RP-HPLC method for simultaneous estimation of vigabatrin, gamma-aminobutyric acid and taurine in biological samples

Keywords: GABA; gamma aminobutyric acid; RP-HPLC; reverse phase-high performance liquid chromatography; NDA; 2, 3‑Naphthalene dicarboxaldehyde; US FDA; United States Food and Drug Administration; IS; internal standard; LLOQ; lower limit of quantification; RP-HPLC

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Simultaneous determination of acetaminophen and oxycodone in human plasma by LC-MS/MS and its application to a pharmacokinetic study

Keywords: LLOQ; lower limit of quantification; LQC; low quality control; MQC; middle quality control; HQC; high quality control; Acetaminophen; Oxycodone; LC-MS/MS; Human plasma; Pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

High-throughput, simultaneous quantitation of hemoglobin adducts of acrylamide, glycidamide, and ethylene oxide using UHPLC-MS/MS

Keywords: AA; acrylamide; EO; ethylene oxide; GA; glycidamide; Hb; hemoglobin; HbAA; hemoglobin adducts of AA; GA; HbGA; EO; HbEO; UHPLC-MS/MS; ultra-high performance liquid chromatography-tandem mass spectrophotometry; IS; internal standard; PFPITC; pentafluorophe

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Determination of d-amphetamine and diphenhydramine in beagle dog plasma by a 96-well formatted liquid-liquid extraction and capillary zone electrophoresis with field-amplified sample stacking

Keywords: CZE; capillary zone electrophoresis; CE; capillary electrophoresis; FASS; field-amplified sample stacking; BGE; background electrolyte; LLE; liquid-liquid extraction; EOF; electroosmotic flow; HD; hydrodynamic; EK; electrokinetic; LC-MS/MS; liquid chrom

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Development of MS Binding Assays targeting the binding site of MB327 at the nicotinic acetylcholine receptor

Keywords: AChE; acetylcholinesterase; CE; collision energy; CXP; collision cell exit potential; DP; declustering potential; EP; entrance potential; ESI; electrospray ionization; FDA; Food and Drug Administration; FIA; flow injection analysis; HI-6; 1-{[(4-carbamoyl

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Development and validation of a sensitive and rapid UHPLC-MS/MS method for the simultaneous quantification of the common active and inactive metabolites of vicagrel and clopidogrel in human plasma

Keywords: AUC; area under the concentration-time curve; Cmax; maximum plasma concentration; EDTA; ethylenediaminetetraacetic acid; EMA; European Medicines Agency; ESI; electrospray ionization; H1, H2, H3, H4; the thiol metabolite isomers of clopidogrel; HPLC; hig

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Pharmacokinetic-pharmacodynamic modeling to study the anti-dysmenorrhea effect of Guizhi Fuling capsule on primary dysmenorrhea rats

Keywords: Guizhi Fuling capsule; Primary dysmenorrhea; Pharmacokinetic-pharmacodynamic model; Anti-dysmenorrhea effect; Ratios of PGE2/PGF2α and 6-Keto-PGF1α/TXB2; ALB; albiflorin; AMY; amygdalin; ARA; arachidonic acid; AUC0-t; area under the time-concentration

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Brain disposition, metabolism and behavioral effects of the synthetic opioid AH-7921 in rats

Keywords: AH-7921; Analgesia; Metabolism; Pharmacokinetics; Rewarding effect; 2-Prop; iso-propylic alcohol; ACN; acetronitrile; ANOVA; analysis of variance; AUC; area under the curve; BBB; blood-brain-barrier; CID; collision-induced dissociation; Cmax; peak concent

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells

Keywords: ECL; Electrochemiluminescence; MSD; Meso Scale Discovery; BSA-NO2; nitrated BSA; LLOQ; lower limit of quantification; 3-nitrotyrosine; Oxidative stress; Nitrative stress; Peroxynitrite; Inflammation; Human serum; Enzyme-linked immunosorbent assay; Mass sp

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Determination of adrenaline, noradrenaline and corticosterone in rodent blood by ion pair reversed phase UHPLC-MS/MS

Keywords: ACN; acetonitrile; ESI; electrospray ionization; FA; formic acid; HFBA; heptafluorobutyric acid; HNO3; nitric acid; HPLC; high performance liquid chromatography; IS; internal standard; LC; liquid chromatography; LLE; liquid, liquid extraction; LLOQ; lower

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

A dried blood spot assay with UPLC-MS/MS for the simultaneous determination of E6005, a phosphodiesterase 4 inhibitor, and its metabolite in human blood

Keywords: B/P; blood to-plasma ratio; DBS; dried blood spot; HQC; high QC; IS; internal standard; LLOQ; lower limit of quantification; LQC; low QC; MQC; middle QC; QC; quality control; RE; relative error; RSD; relative standard deviation; ULOQ; upper limit of quant

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Role of efflux transporters in the absorption, distribution and elimination in rodents of a novel PDE4 inhibitor, CHF6001

Keywords: ADME; absorption, distribution, metabolism and excretion; AUC0-t(last); area under the concentration-time curve up to the last measurable concentration; AUCinf; area under the concentration-time curve up to infinity; AUCτ; area under the concentration-ti

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Investigation of pharmacokinetic parameters of bakuchicin isolated from Psoralea corylifolia in mice

Keywords: LC-MS/MS; liquid chromatography-tandem mass spectrometry; MRM; multiple reaction-monitoring; ESI; electrospray ionization; LOD; limit of detection; LLOQ; lower limit of quantitation; Bakuchicin; Psoralea corylifolia; Pharmacokinetics; Bioavailability; Liq

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Selective and accurate C5 acylcarnitine quantitation by UHPLC-MS/MS: Distinguishing true isovaleric acidemia from pivalate derived interference

Keywords: IVA; isovaleric acidemia; SCADD; short chain acyl-CoA dehydrogenase deficiency; GAI; glutaric acidemia type I; SCX; strong cation exchange; SPE; solid-phase extraction; LLOQ; lower limit of quantitation; ULOQ; upper limit of quantitation; CAP; College of

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Biodistribution and safety of a live attenuated tetravalent dengue vaccine in the cynomolgus monkey

Keywords: Live attenuated vaccine; Dengue; Cynomolgus monkey; Toxicity; Biodistribution; Shedding; CYD-TDV; live attenuated tetravalent dengue vaccine; DENV; dengue virus; DF; dengue fever; DHF; dengue hemorrhagic fever; DSS; dengue shock syndrome; ELISA; enzyme-li

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه