دانلود مقالات ISI درباره حد پایین کمیت سنجی + ترجمه فارسی

Measurement of apixaban, dabigatran, edoxaban and rivaroxaban in human plasma using automated online solid-phase extraction combined with ultra-performance liquid chromatography-tandem mass spectrometry and its comparison with coagulation assays

Keywords: حد پایین کمیت سنجی; aPTT; activated partial thromboplastin time; BEH; bridged ethyl hybrid; CV; coefficient of variation; DOACs; direct oral anticoagulants; DTI; direct thrombin inhibitor(s); IS; internal standard; MRM; multiple reaction monitoring mode; MS/MS; tandem mass s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Efficacy of Glecaprevir/Pibrentasvir for 8 or 12 Weeks in Patients With Hepatitis C Virus Genotype 2, 4, 5, or 6 Infection Without Cirrhosis

Keywords: حد پایین کمیت سنجی; Direct-acting Antiviral; DAA; Short-duration; Pangenotypic; ALT; alanine aminotransferase; CI; confidence interval; DAA; direct-acting antiviral; G/P; glecaprevir/pibrentasvir; HCV; hepatitis C virus; IFN; interferon; ITT; intention-to-treat; LLOQ; lower

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Cellulose-based amorphous solid dispersions enhance rifapentine delivery characteristics in vitro

Keywords: حد پایین کمیت سنجی; Rifapentine (PubChem CID: 6323497); Rifampicin (PubChem CID: 5458213); 3-Formylrifamycin (PubChem CID: 6438444); Hydroxypropylmethylcellulose acetate succinate (PubChem CID: 121950); ASD; amorphous solid dispersion; AUC; area under the curve; CASub; cellu

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Effective phospholipids removing microelution-solid phase extraction LC-MS/MS method for simultaneous plasma quantification of aripiprazole and dehydro-aripiprazole: Application to human pharmacokinetic studies

Keywords: حد پایین کمیت سنجی; ARI; aripiprazole; AUC; area under curve; CAL; calibration standard; CID; collision-induced dissociation; Cmax; maximum plasma concentration; CV; coefficient of variation; CYP; cytochrome P450; DAD; diode array detection; DARI; dehydro-aripiprazole; EDTA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Microdialysis combined with RRLC-MS/MS for the pharmacokinetics of two major alkaloids of Bi qi capsule and the potential roles of P-gp and BCRP on their penetration

Keywords: حد پایین کمیت سنجی; BQC; Bi qi capsule; BBB; blood-brain barrier; RRLC-MS/MS; rapid resolution liquid chromatography -tandem mass spectrometry; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; CNS; central nervous system; CSF; cerebrospinal fluid; LLOQ; lower li

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

A new cause of false positive voriconazole levels: Watch your collection tubes!

Keywords: حد پایین کمیت سنجی; TDM; Therapeutic drug monitoring; VOR; Voriconazole; HPLC-UV; High-performance liquid chromatography with ultraviolet detector; FDA; Food and drug administration; EMEA; European Medicines Agency; PRE; Percentage relative error; LLOQ; Lower limit of quanti

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Determination of 12 commonly found compounds in DUID cases in whole blood using fully automated supported liquid extraction and UHPLC-MS/MS

Keywords: حد پایین کمیت سنجی; DUID; driving under influence of drugs; UHPLC-MS/MS; ultra high performance liquid chromatography-tandem mass spectrometry; SLE; supported liquid extraction; IS; internal standard; QC; quality control; ESI; electrospray ionization; R2; the coefficient of

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

A rapid, simple, and high-throughput UPLC-MS/MS method for simultaneous determination of bioactive constituents in Salvia miltiorrhiza with positive/negative ionization switching

Keywords: حد پایین کمیت سنجی; CV; coefficient of variance; ESI; electrospray ionization; LC; liquid chromatography; LOQ; limit of quantification; LOD; limit of detection; LLOQ; lower limit of quantification; MRM; multiple reaction monitoring; MS; mass spectrometer; MS/MS; tandem mass

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of Baoyuan decoction, a traditional Chinese medicine formula, on the activities and mRNA expression of seven CYP isozymes in rats

Keywords: حد پایین کمیت سنجی; BYD; Baoyuan decoction; TCM; traditional Chinese medicine; CYP; cytochrome P450; HDI; herb-drug interaction; IS; internal standard; RT-PCR; real-time reverse transcription-polymerase chain reaction; QC; quality control; ESI; electrospray ionization; RSD;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Comparative pharmacokinetics of six coumarins in normal and breast cancer bone-metastatic mice after oral administration of Wenshen Zhuanggu Formula

Keywords: حد پایین کمیت سنجی; WSZG; Wenshen Zhuanggu formula; LC-MS/MS; liquid chromatography tandem mass spectrometry; TCM; traditional Chinese medicine; DMEM; Dulbecco's Modified Eagle's Medium; IS; internal standard; BLI; bioluminescent imaging; HE; hematoxylin and eosin; ZnSO4; Zi

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Rapid determination of 3′, 4′-dimethoxy flavonol-3-β-d-glucopyranoside in rat plasma by LC-MS/MS method followed by protein precipitation

Keywords: حد پایین کمیت سنجی; LC-MS/MS; liquid chromatography/tandem mass spectrometry; LLOQ; lower limit of quantification; IS; internal standard; QC; quality control; DF3G; 3′,4′-dimethoxy flavonol-3-β-d-glucopyranoside; HPLC; high performance liquid chromatography; SD; standar

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Pharmacokinetics and safety of a single dose of the novel LAMA/LABA fixed-dose combination of glycopyrronium/formoterol fumarate dihydrate metered dose inhaler, formulated using co-suspension delivery technology, in Japanese healthy subjects

Keywords: حد پایین کمیت سنجی; GFF MDI; Chronic obstructive pulmonary disease; Co-suspension delivery technology; LAMA/LABA; Pharmacokinetics; AE; adverse event; AUC0-12; area under the curve from 0 to 12 h; AUC0-t; area under the curve from 0 to time of the last measurable plasm

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the EGFR inhibitors afatinib, erlotinib and osimertinib, the ALK inhibitor crizotinib and the VEGFR inhibitor nintedanib in human plasma from non-small cell lung canc

Keywords: حد پایین کمیت سنجی; AFAT; afatinib; ALK; anaplastic lymphoma kinase; CRIZ; crizotinib; CS; calibration standard; CV; coefficient of variation; DMSO; dimethylsulfoxide; EGFR; epidermal growth factor receptor; ERLO; erlotinib; IQC; internal quality control; IS; internal standa

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

RP-HPLC method for simultaneous estimation of vigabatrin, gamma-aminobutyric acid and taurine in biological samples

Keywords: حد پایین کمیت سنجی; GABA; gamma aminobutyric acid; RP-HPLC; reverse phase-high performance liquid chromatography; NDA; 2, 3‑Naphthalene dicarboxaldehyde; US FDA; United States Food and Drug Administration; IS; internal standard; LLOQ; lower limit of quantification; RP-HPLC

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Safety and pharmacokinetics of budesonide/glycopyrronium/formoterol fumarate dihydrate metered dose inhaler (BGF MDI) in healthy adult subjects of Japanese descent

Keywords: حد پایین کمیت سنجی; Chronic obstructive pulmonary disease; Co-suspension delivery technology; ICS/LAMA/LABA; Western; Japanese; Triple fixed-dose combination; AE; adverse event; AUC0-12; area under the plasma concentration-time curve from 0 to 12 h; AUC0-∞; area un

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Simultaneous determination of acetaminophen and oxycodone in human plasma by LC-MS/MS and its application to a pharmacokinetic study

Keywords: حد پایین کمیت سنجی; LLOQ; lower limit of quantification; LQC; low quality control; MQC; middle quality control; HQC; high quality control; Acetaminophen; Oxycodone; LC-MS/MS; Human plasma; Pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Determination of d-amphetamine and diphenhydramine in beagle dog plasma by a 96-well formatted liquid-liquid extraction and capillary zone electrophoresis with field-amplified sample stacking

Keywords: حد پایین کمیت سنجی; CZE; capillary zone electrophoresis; CE; capillary electrophoresis; FASS; field-amplified sample stacking; BGE; background electrolyte; LLE; liquid-liquid extraction; EOF; electroosmotic flow; HD; hydrodynamic; EK; electrokinetic; LC-MS/MS; liquid chrom

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Development of MS Binding Assays targeting the binding site of MB327 at the nicotinic acetylcholine receptor

Keywords: حد پایین کمیت سنجی; AChE; acetylcholinesterase; CE; collision energy; CXP; collision cell exit potential; DP; declustering potential; EP; entrance potential; ESI; electrospray ionization; FDA; Food and Drug Administration; FIA; flow injection analysis; HI-6; 1-{[(4-carbamoyl

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Development and validation of a sensitive and rapid UHPLC-MS/MS method for the simultaneous quantification of the common active and inactive metabolites of vicagrel and clopidogrel in human plasma

Keywords: حد پایین کمیت سنجی; AUC; area under the concentration-time curve; Cmax; maximum plasma concentration; EDTA; ethylenediaminetetraacetic acid; EMA; European Medicines Agency; ESI; electrospray ionization; H1, H2, H3, H4; the thiol metabolite isomers of clopidogrel; HPLC; hig

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Transhepatic bile acid kinetics in pigs and humans

Keywords: حد پایین کمیت سنجی; Bile acids; TGR5; Porcine; Postprandial; Portal concentrations; BAs; bile acids; ASBT; apical sodium-dependent bile acid transporter; OST; organic solute transporter; NTCP; taurocholate cotransporting polypeptide; OATP; organic anion transporting polypept

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Pharmacokinetic-pharmacodynamic modeling to study the anti-dysmenorrhea effect of Guizhi Fuling capsule on primary dysmenorrhea rats

Keywords: حد پایین کمیت سنجی; Guizhi Fuling capsule; Primary dysmenorrhea; Pharmacokinetic-pharmacodynamic model; Anti-dysmenorrhea effect; Ratios of PGE2/PGF2α and 6-Keto-PGF1α/TXB2; ALB; albiflorin; AMY; amygdalin; ARA; arachidonic acid; AUC0-t; area under the time-concentration

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Brain disposition, metabolism and behavioral effects of the synthetic opioid AH-7921 in rats

Keywords: حد پایین کمیت سنجی; AH-7921; Analgesia; Metabolism; Pharmacokinetics; Rewarding effect; 2-Prop; iso-propylic alcohol; ACN; acetronitrile; ANOVA; analysis of variance; AUC; area under the curve; BBB; blood-brain-barrier; CID; collision-induced dissociation; Cmax; peak concent

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells

Keywords: حد پایین کمیت سنجی; ECL; Electrochemiluminescence; MSD; Meso Scale Discovery; BSA-NO2; nitrated BSA; LLOQ; lower limit of quantification; 3-nitrotyrosine; Oxidative stress; Nitrative stress; Peroxynitrite; Inflammation; Human serum; Enzyme-linked immunosorbent assay; Mass sp

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Determination of adrenaline, noradrenaline and corticosterone in rodent blood by ion pair reversed phase UHPLC-MS/MS

Keywords: حد پایین کمیت سنجی; ACN; acetonitrile; ESI; electrospray ionization; FA; formic acid; HFBA; heptafluorobutyric acid; HNO3; nitric acid; HPLC; high performance liquid chromatography; IS; internal standard; LC; liquid chromatography; LLE; liquid, liquid extraction; LLOQ; lower

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

A dried blood spot assay with UPLC-MS/MS for the simultaneous determination of E6005, a phosphodiesterase 4 inhibitor, and its metabolite in human blood

Keywords: حد پایین کمیت سنجی; B/P; blood to-plasma ratio; DBS; dried blood spot; HQC; high QC; IS; internal standard; LLOQ; lower limit of quantification; LQC; low QC; MQC; middle QC; QC; quality control; RE; relative error; RSD; relative standard deviation; ULOQ; upper limit of quant

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Biodistribution and safety of a live attenuated tetravalent dengue vaccine in the cynomolgus monkey

Keywords: حد پایین کمیت سنجی; Live attenuated vaccine; Dengue; Cynomolgus monkey; Toxicity; Biodistribution; Shedding; CYD-TDV; live attenuated tetravalent dengue vaccine; DENV; dengue virus; DF; dengue fever; DHF; dengue hemorrhagic fever; DSS; dengue shock syndrome; ELISA; enzyme-li

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Is a deuterated internal standard appropriate for the reliable determination of olmesartan in human plasma?

Keywords: حد پایین کمیت سنجی; CI; confidence interval; EMA; European Medicines Agency; FDA; US Food and Drug Administration; IS; internal standard; LLOQ; lower limit of quantification; OLM; olmesartan; SIL; stable isotopically labelled; Olmesartan; Liquid chromatography/mass spectrome

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Immune responses in DAA treated chronic hepatitis C patients with and without prior RG-101 dosing

Keywords: حد پایین کمیت سنجی; Chronic hepatitis C; DAA treatment; Immune response; miRNA-122; HCV; hepatitis C virus; IP-10; interferon gamma-induced protein; CHC; chronic hepatitis C; DAAs; direct acting antivirals; SVR; sustained virological response; miR-122; microRNA-122; RAS; res

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Development and validation of an ELISA method for the quantification of nivolumab in plasma from non-small-cell lung cancer patients

Keywords: حد پایین کمیت سنجی; ALP; Alkaline Phosphatase; ALT; alanine transaminase; AST; aspartate aminotransferase; BSA; Bovine Serum Albumin; CRP; C-Reactive Protein; CV; Coefficient of Variation; ECOG; Eastern Cooperative Oncology Group; EMA; European Medicines Agency; FDA; Food an

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

The pharmacokinetics and tissue distribution of coumaroylspinosin in rat: A novel flavone C-glycoside derived from Zizyphi Spinosi Semen

Keywords: حد پایین کمیت سنجی; AUC; area under the curve; CE; collision energy; CL; clearance rate; ESI; electrospray ionization; IS; internal standard; LLOQ; lower limit of quantification; MRM; multiple reaction monitoring; MRT; mean residence time; QC; quality control; RE; relative e

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Simultaneous quantification of 25-hydroxyvitamin D3-3-sulfate and 25-hydroxyvitamin D3-3-glucuronide in human serum and plasma using liquid chromatography-tandem mass spectrometry coupled with DAPTAD-derivatization

Keywords: حد پایین کمیت سنجی; LC-MS/MS; liquid chromatography-tandem mass spectrometry; DAPTAD; 4-(4′-dimethylaminophenyl)-1,2,4-triazoline-3,5-dione; LLE; liquid-liquid extraction; LLOQ; lower limit of quantification; MRM; multiple reaction monitoring; 25-OHD3; 25-hydroxyvita

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Pharmacokinetic based study on “lagged stimulation” of Curcumae Longae Rhizoma - Piper nigrum couplet in their main active components' metabolism using UPLC-MS-MS

Keywords: حد پایین کمیت سنجی; Curcumae Longae Rhizoma; Piper nigrum; UHPLC-MS-MS; Lagged stimulation; Pharmacokinetics; TCM; Traditional Chinese Medicine; Cur; curcumin; Pip; piperine; UPLC-MS-MS; ultra-performance liquid chromatography-mass spectrometry; ESI; electrospray ionizatio

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Development and validation of a UPLC-MS/MS assay for the determination of gemcitabine and its L-carnitine ester derivative in rat plasma and its application in oral pharmacokinetics

Keywords: حد پایین کمیت سنجی; Gemcitabine; L-carnitine; Prodrug; Pharmacokinetics; UPLC/MS/MS; JDR; 2'-deoxy-2', 2'-difluoro-N-((4-amino-4-oxobutanoyl)oxy)-4-(trimethyl amm-onio) butanoate-cytidine; SPE; solid-phase extraction; LLOQ; lower limit of quantification; PK; pharmacokinetic;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Determination of a novel anticancer AMPK activator hernandezine in rat plasma and tissues with a validated UHPLC-MS/MS method: Application to pharmacokinetics and tissue distribution study

Keywords: حد پایین کمیت سنجی; AUC0-t; area under the peak-time curve from time zero to last sampling time; ESI; electrospray ionization; IS; internal standard; Ke; elimination rate constant; LLOQ; lower limit of quantification; MRM; multiple reaction monitoring; t1/2; biological hal

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

A new fluorescence-based method for characterizing in vitro aerosol exposure systems

Keywords: حد پایین کمیت سنجی; CMAG; condensation monodisperse aerosol generator; DSF; disodium fluorescein; VC24/48; Vitrocell® 24/48 aerosol exposure system; PBS; phosphate buffered saline; PM; particulate matter; GVP; gas-vapor phase; APS; aerodynamic particle sizer; e-cigarettes;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Are Idiopathic Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Related to Drugs in Food? The Example of Phenylbutazone

Keywords: حد پایین کمیت سنجی; LLOQ; lower limit of quantification; NSAID; nonsteroidal anti-inflammatory drug; OPB; oxyphenbutazone; PBZ; phenylbutazone; SBZ; suxibuzone; SJS; Stevens-Johnson syndrome; TEN; toxic epidermal necrolysis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Sex-specific and inter-individual differences in biomarkers of selenium status identified by a calibrated ELISA for selenoprotein P

Keywords: حد پایین کمیت سنجی; Ab; antibody; CV; coefficient of variation; ELISA; enzyme-linked immunosorbent assay; GPX3; glutathione peroxidase 3; LLOQ; lower limit of quantification; LOD; limit of detection; LRP; lipoprotein receptor-related protein; mAb; monoclonal antibody; pAb; p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Roles of Angiotensin Peptides and Recombinant Human ACE2 in Heart Failure

Keywords: حد پایین کمیت سنجی; angiotensin II; angiotensin-(1-7); chymase; dilated cardiomyopathy; renin-angiotensin system; ACE; angiotensin-converting enzyme; ACEI; angiotensin-converting enzyme inhibitor; AHF; acute heart failure; Ang I; angiotensin-(1-10); Ang II; angiotensin-(

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Inter-laboratory skin distribution study of 4-n-butyl resorcinol: The importance of liquid chromatography/mass spectrometry (HPLC-MS/MS) bioanalytical validation

Keywords: حد پایین کمیت سنجی; ACN; acetonitrile; AD; applied dose; APCI; atmospheric pressure chemical ionization; De; dermis; Ep; epidermis; ER; extraction recovery; ESI; electrospray ionization; FA; formic acid; IS; internal standard; LC; liquid chromatography; LLOQ; lower limit of

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

A simple and rapid UHPLC-MS/MS method for the quantitation of the dual aurora kinase A/B inhibitor SCH-1473759 in murine plasma

Keywords: حد پایین کمیت سنجی; UHPLC; ultra-high performance liquid chromatography; MS; mass spectrometry; MS/MS; tandem mass spectrometry; QC; quality control; LLOQ; lower limit of quantification; ACN; acetonitrile; %DEV; percent deviation from the nominal value; WRP; within-run preci

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Efficacy of Ledipasvir Plus Sofosbuvir for 8 or 12 Weeks in Patients With Hepatitis C Virus Genotype 2 Infection

Keywords: حد پایین کمیت سنجی; Antiviral agents; Direct-acting antivirals; Polymerase inhibitor; NS5A inhibitor; EC50; half-maximal effective concentration; HCV; hepatitis C virus; LLOQ; lower limit of quantification; RASs; resistance-associated substitutions; SVR; sustained virologica

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

An LC-MS/MS method for simultaneous determination of nine steroidal saponins from Paris polyphylla var. in rat plasma and its application to pharmacokinetic study

Keywords: حد پایین کمیت سنجی; UPLC; ultra-performance liquid chromatography; I.S.; internal standard; AUC; area under the curve; QC; quality control; LLOQ; lower limit of quantification; MPA; mobile phase A; MPB; mobile phase B; Paris polyphylla; Steroidal saponins; Pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Simultaneous quantification of estrogens, their precursors and conjugated metabolites in human breast cancer cells by LC-HRMS without derivatization

Keywords: حد پایین کمیت سنجی; 3β-HSD; 3β-hydroxysteroiddehydrogenase; 17β-HSD; 17β-hydroxysteroiddehydrogenase; AD; androstenedione; DHEA; dehydroepiandrosterone; DHEA-S; dehydroepiandrosterone-3-sulfate; DMEM; Dulbecco's Modified Eagle Medium F-12; DMSO; dimethylsulfoxide; DPBS;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Ketamine metabolites with antidepressant effects: Fast, economical, and eco-friendly enantioselective separation based on supercritical-fluid chromatography (SFC) and single quadrupole MS detection

Keywords: حد پایین کمیت سنجی; CYP; cytochrome P450; DHK; dehydronorketamine; KET; ketamine; NK; norketamine; NK-d4; norketamine-d4; HNK; hydroxynorketamine; SFC-MS; supercritical-fluid chromatography single quadrupole mass spectrometry; LLOQ; lower limit of quantification; LOD; limit

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Method validation and nanoparticle characterization assays for an innovative amphothericin B formulation to reach increased stability and safety in infectious diseases

Keywords: حد پایین کمیت سنجی; DDS; drug delivery system; NLC; nanostructured lipid carrier; Blank NLC; unloaded nanostructured lipid carrier; AmB; amphotericin B; NLC-AmB; amphotericin B loaded nanostructured lipid carrier; DLS; dinamic light scattering; PdI; polydispersivity index; A

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Perspectives on using a multiplex human kidney safety biomarker panel to detect cisplatin-induced tubular toxicity in male and female Cynomolgus monkeys

Keywords: حد پایین کمیت سنجی; AKI; acute kidney injury; ALB; albumin; α1M; alpha 1 microglobulin; αGST; alpha glutathione S-transferase; β2M; beta 2 microglobulin; BUN; blood urea nitrogen; CALB; calbindin D28k; CLU; clusterin; Cr; creatinine; CYS C; cystatin C; DIKI; drug-induced

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Andrographolide-loaded nanoparticles for brain delivery: Formulation, characterisation and in vitro permeability using hCMEC/D3 cell line

Keywords: حد پایین کمیت سنجی; AG; andrographolide; ATM; adsorptive-mediated transcytosis; BBB; blood-brain barrier; BSA; bovine serum albumin; CNS; central nervous system; DLS; Dynamic Light Scattering; DMSO; dimethyl sulfoxide; ECA; ethylcyanoacrylate; EE; encapsulation efficiency; E

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

A simple dilute and shoot approach incorporated with pentafluorophenyl (PFP) column based LC-MS/MS assay for the simultaneous determination of trimethylamine N-oxide and trimethylamine in spot urine samples with high throughput

Keywords: حد پایین کمیت سنجی; PFP; pentafluorophenyl; TMAO; trimethylamine N-oxide; TMA; trimethylamine; FMO3; flavin-containing monooxygenase 3; TMAU; trimethylaminuria; 1H NMR; proton nuclear magnetic resonance spectrometry; GC; gas chromatography; MS; mass spectrometer; LC; liquid

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds

Keywords: حد پایین کمیت سنجی; Acr-dG; 1,N2-propanodeoxyguanosine; AGEs; advanced glycation end-product; ALEs; advanced lipoxidation end product; ApoB100; apolipoprotein B100; ApoE; apolipoprotein E; ARP; aldehyde reactive probe; AspN; endoproteinase AspN (flavastacin); βLG; β-lactog

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids

Keywords: حد پایین کمیت سنجی; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; EDCs; endocrine disrupting chemicals; LC-MS; liquid chromatography-mass spectrometry; LOD; limit of detection; LLOQ; lower limit of quantification; MTT; 3-(4,5-dimethylthiazol-2-yl)-2

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه