Identification of benzoxazole analogs as novel, S1P3 sparing S1P1 agonists
Keywords: لنفوپنی; Sphingosine-1-phosphate (S1P); Agonist; Lymphopenia; Multiple sclerosis;
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The Wisconsin approach to newborn screening for severe combined immunodeficiency
Keywords: لنفوپنی; Severe combined immunodeficiency; T-cell receptor excision circle; lymphopenia; newborn screeningAGA, Adjusted gestational age; HCT, Hematopoietic cell transplantation; NBS, Newborn screening; NK, Natural killer; RAC2, RAS-related C3 botulinum toxin subst
Predictive value of peripheral blood lymphocyte count in breast cancer patients treated with primary chemotherapy
Keywords: لنفوپنی; Breast cancer; Neoadjuvant chemotherapy; Lymphocyte; Lymphopenia; Prognosis; Anti-cancer immunity
Lymphopenia induced by a novel selective S1P1 antagonist structurally unrelated to S1P
Keywords: لنفوپنی; S1P; sphingosine 1-phosphate; S1P1; type 1 sphingosine 1-phosphate receptor; CHS; contact hypersensitivity response; HEK293; human embryonic kidney cell line; CHO-K1; Chinese hamster ovary cell line; HTS; high-throughput screening; GTP; guanosine-5â²-tri
Both exogenous commensal and endogenous self antigens stimulate T cell proliferation under lymphopenic conditions
Keywords: لنفوپنی; Homeostasis; T cell; Commensal antigen; FTY720; Self antigen; Lymphopenia
Pharmacological effects of CS-0777, a selective sphingosine 1-phosphate receptor-1 modulator: Results from a 12-week, open-label pilot study in multiple sclerosis patients
Keywords: لنفوپنی; S1PR1; Lymphopenia; CD8 T cell subsets; Bradycardia; Fingolimod; Autoimmune disease
Tissue specificity in nickel uptake and induction of oxidative stress in kidney and spleen of goldfish Carassius auratus, exposed to waterborne nickel
Keywords: لنفوپنی; Nickel toxicity; Goldfish; Lymphopenia; Oxidative stress; Antioxidant enzymes
Primary T-cell immunodeficiency with immunodysregulation caused by autosomal recessive LCK deficiency
Keywords: لنفوپنی; CD4; lymphopenia; autoinflammation; recurrent infections; LCK, SRC tyrosine kinase; genetic defect; immunodeficiency; T-cell receptor signaling; CDR3; Complementary-determining region 3; CD62L; CD62 ligand; CID; Combined immunodeficiency; ERK; Extracellul
The sphingosine-1-phosphate receptor-1 antagonist, W146, causes early and short-lasting peripheral blood lymphopenia in mice
Keywords: لنفوپنی; S1P; sphigosine-1-phosphate; S1P1; sphingosine-1-phosphate receptor 1; Sphingosine-1-phosphate receptors; Lymphocytes; Lymph nodes; Lymphopenia; W146; S1P1 agonists;
BB rat Gimap gene expression in sorted lymphoid T and B cells
Keywords: لنفوپنی; Gimap; Lymphopenia; Autoimmunity; Type 1 diabetes
Étude du profil immunitaire de sujets âgés hospitalisés en unité de court séjour gériatrique
Keywords: لنفوپنی; Immunosénescence; Sujet âgé; Polypathologie; Vitamine D; LymphopénieImmunosenescence; Elderly; Polypathology; Vitamin D; Lymphopenia
Hematologic toxicities in cancer patients treated with the multi-tyrosine kinase sorafenib: A meta-analysis of clinical trials
Keywords: لنفوپنی; Vascular endothelial growth factor receptor; Targeted therapy; Tyrosine kinase inhibitors; Sorafenib; Anemia; Neutropenia; Lymphopenia; Thrombocytopenia; Bone marrow toxicities; Hematologic toxicities; Meta-analysis
CNS-derived CCL21 is both sufficient to drive homeostatic CD4+ T cell proliferation and necessary for efficient CD4+ T cell migration into the CNS parenchyma following Toxoplasma gondii infection
Keywords: لنفوپنی; Autoimmunity; Glia; Lymphopenia; Microglia; Multiple sclerosis; Neuroinflammation; Neurodegeneration; T cell trafficking
Discovery of a novel series of potent S1P1 agonists
Keywords: لنفوپنی; S1P1; Sphingosine-1-phosphate; Structure–activity relationships; Hit-to-lead; Lymphopenia
Exploration of amino alcohol derivatives as novel, potent, and highly selective sphingosine-1-phosphate receptor subtype-1 agonists
Keywords: لنفوپنی; Sphingosine-1-phosphate (S1P) agonist; S1P1 agonists; Phenylamide; Phenylimidazole; Immunosuppressants; Lymphopenia
Reconstitution of circulating lymphocyte counts in FTY720-treated MS patients
Keywords: لنفوپنی; FTY720; Fingolimod; multiple sclerosis; lymphocyte; lymphopenia; lymph node;
Expression of CD55 and CD59 on peripheral blood cells from systemic lupus erythematosus (SLE) patients
Keywords: لنفوپنی; Systemic lupus erythematosus; SLE; CD55; CD59; Lymphopenia; Cytopenias; Complement system; GPI; Flow cytometry; Immunophenotyping
Prolonged depletion of circulating CD4+ T lymphocytes and acute monocytosis after pantropic canine coronavirus infection in dogs
Keywords: لنفوپنی; Canine coronavirus; Lymphopenia; CD4+ T cell depletion; Monocytosis; CD8+ T cells; B cells
Immunosuppressive therapy exacerbates autoimmunity in NOD mice and diminishes the protective activity of regulatory T cells
Keywords: لنفوپنی; NOD; Radiation; Lymphopenia; Homeostatic expansion; Lymphopenia-induced proliferation; Regulatory T cell; Type 1 diabetes
Selective Changes in the Immune Profile of Tumor-Draining Lymph Nodes After Different Neoadjuvant Chemoradiation Regimens for Locally Advanced Cervical Cancer
Keywords: لنفوپنی; Cervical cancer; Chemoradiation; Tumor-draining lymph nodes; Immune system; Lymphopenia;
Secondary immunodeficiencies, including HIV infection
Keywords: لنفوپنی; Secondary immunodeficiency; immunosuppression; lymphopenia; AIDSGvHD, Graft-versus-host disease; HAART, Highly active antiretroviral therapy; IRIS, Immune reconstitution inflammatory syndrome
Treatment with a sphingosine analog does not alter the outcome of a persistent virus infection
Keywords: لنفوپنی; Viral persistence; FTY720; Lymphopenia; Lymphocytic choriomeningitis virus; Sphingosine; Influenza; Sphingosine-1-phosphate receptor 1; AUY954
Le médecin du travail face à une anomalie leucocytaire
Keywords: لنفوپنی; Hémogramme; Lymphopénie; Leucocytes; Imprimerie; Exposition professionnelle; Blood cell count; Lymphopenia; Leukocytes; Printing; Occupational exposure;
T-cell-based Therapies for Malignancy and Infection in Childhood
Keywords: لنفوپنی; Hematopoietic stem cell transplantation; Pediatrics; Adoptive immunotherapy; Tumor vaccines; Tumor antigens; Lymphopenia; Immune reconstitution; Chimeric antigen receptor;
Synthesis and evaluation of arylalkoxy- and biarylalkoxy-phenylamide and phenylimidazoles as potent and selective sphingosine-1-phosphate receptor subtype-1 agonists
Keywords: لنفوپنی; S1P; S1P1 agonist; EDG1; Lymphopenia; FTY-720; Sphingosine-1-phosphate; Arylalkoxy-phenylamide; Arylalkoxy-phenylimidazoles; Biarylalkoxy-phenylamide; Biarylalkoxyphenylimidazoles
The early immunological response to acute ischemic stroke: Differential gene expression in subpopulations of mononuclear cells
Keywords: لنفوپنی; lymphocytes; lymphopenia; macrophages; monocytes; oxLDL; PBMCbp, base pair; CD, cluster of differentiation; cDNA, complementary DNA; CD40L, CD40 ligand; CIDS, CNS injury-induced immunodepression; CPP32, caspase-3; CRP, C-reactive protein; DNase, deoxyribo
Synthesis and biological evaluation of sphingosine kinase substrates as sphingosine-1-phosphate receptor prodrugs
Keywords: لنفوپنی; Sphingosine-1-phosphate; FTY-720; Heterocycles; Pro-drugs; Lymphopenia; Structure–activity-relationship
Higher in vitro susceptibility of human T cells to H5N1 than H1N1 influenza viruses
Keywords: لنفوپنی; Influenza A virus; H1N1; H5N1; Human lymphocyte; CD4+ T cell; Lymphopenia;
Pathogenic mechanisms of B-lymphocyte dysfunction in HIV disease
Keywords: لنفوپنی; HIV; B cells; immunopathogenesis; immune activation; lymphopenia; apoptosis; ART; Antiretroviral therapy; VH3; Variable heavy-chain family member 3;
Clinical aspects and prognostic factors of leptospirosis in adults. Retrospective study in France
Keywords: لنفوپنی; Leptospirosis; Zoonosis; Emerging disease; Clinical signs; Diagnosis; Treatment; Prognostic factors; Lymphopenia
Post-transplant adoptive T-cell immunotherapy
Keywords: لنفوپنی; T cell; immune reconstitution; lymphopenia; haematopoietic stem cell transplantation; immunotherapy
Pneumocystose pulmonaire chez les patients non VIH : à propos de trois cas
Keywords: لنفوپنی; Pneumocystis jiroveci; Patients immunodéprimés; Lymphopénie; Lavage bronchoalvéolairePneumocystis jiroveci; Immunocompromised patients; Lymphopenia; Bronchoalveolar lavage
Thoracoscopic talc poudrage decreases T-lymphocytes in the peripheral blood
Keywords: لنفوپنی; Pleurodesis; Thoracoscopy; Talc; T-lymphocytes; Lymphopenia
Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function
Keywords: لنفوپنی; Amyotrophic lateral sclerosis (ALS); ALS2; ALS2 knockout mice; Lymphopenia; Hematopoietic stem and progenitor cells; Cytokine-stimulated proliferation;
GIMAP5 regulates mitochondrial integrity from a distinct subcellular compartment
Keywords: لنفوپنی; BB-DP; Biobreeding diabetes-prone; ER; endoplasmic reticulum; GIMAP5; GTPase of immunity-associated nucleotide binding protein 5; rGIMAP5; rat GIMAP5; IAN5; immune associated nucleotide-binding protein 5; TMRE; tetramethylrhodamine ethyl ester; GIMAP5; Ly
The role of complement regulatory proteins (CD55 and CD59) in the pathogenesis of autoimmune hemocytopenias
Keywords: لنفوپنی; CD55; CD59; Autoimmune hemolytic anemia; Autoimmune thrombocytopenia; Lymphopenia; Systemic lupus erythematosus
Differential modulation of mitogen driven proliferation and homeostasis driven proliferation of T cells by rapamycin, Ly294002 and chlorophyllin
Keywords: لنفوپنی; Lymphopenia; Anergy; Antioxidant; Homeostasis
A “possible” involvement of TNF-alpha in apoptosis induction in peripheral blood lymphocytes of cats with feline infectious peritonitis
Keywords: لنفوپنی; FIP; Apoptosis; TNF-alpha; TNF-receptor; Lymphopenia; CD8+ cell
T cell immune reconstitution following lymphodepletion
Keywords: لنفوپنی; Immune reconstitution; Lymphopenia; Thymopoiesis; Thymus; Homeostatic peripheral expansion; GVHD; Immunotherapy
Treatment with rituximab affects both the cellular and the humoral arm of the immune system in patients with SLE
Keywords: لنفوپنی; Autoimmunity; Lymphocytes; Autoantibodies; Lupus; Nephritis; Lymphopenia; Flow cytometry
T cell homeostasis in steady state and lymphopenic conditions
Keywords: لنفوپنی; T cell homeostasis; Lymphopenia; Lymphopenia-induced proliferation
Role of vascular cell adhesion molecules and leukocyte apoptosis in the lymphopenia and thrombocytopenia of patients with severe acute respiratory syndrome (SARS)
Keywords: لنفوپنی; SARS; sVCAM-1; sFasL; Apoptosis; Lymphopenia; Caspase
Autoimmunity during lymphopenia: A two-hit model
Keywords: لنفوپنی; IRIS; Autoimmunity; Immunoregulation; Tolerance; Lymphopenia; Homeostatic peripheral espansion;
Clinico-Pathological Study of Hodgkin's Disease in King Abdulaziz University Hospital, Jeddah
Keywords: لنفوپنی; Epidemiology; Histopathology; Hodgkin's disease; Lymphopenia
Clinical presentation of leptospirosis: a retrospective study of 34 patients admitted to a single institution in metropolitan France
Keywords: لنفوپنی; Diagnosis; emerging infection; leptospirosis; lymphopenia; symptoms; zoonoses;
T-cell Lymphopenia Associated with Infliximab and Cyclophosphamide
Keywords: لنفوپنی; Rheumatoid arthritis; Infliximab; Cyclophosphamide; Leukopenia; Lymphopenia; CD4; T-cell;
Two-tiered universal newborn screening strategy for severe combined immunodeficiency
Keywords: لنفوپنی; Interleukin-7; TRECs; Newborn screening; Immunodeficiency; Severe combined immunodeficiency; Lymphopenia;
Synthesis, stability, and implications of phosphothioate agonists of sphingosine-1-phosphate receptors
Keywords: لنفوپنی; Sphingosine-1-phosphate; Phosphothioate; Lymphopenia
Endogenous proliferation: Burst-like CD4 T cell proliferation in lymphopenic settings
Keywords: لنفوپنی; CD4 T cells; Endogenous proliferation; Homeostasis; Lymphopenia;
DR.lyp/lyp bone marrow maintains lymphopenia and promotes diabetes in lyp/lyp but not in +/+ recipient DR.lyp BB rats
Keywords: لنفوپنی; BB rat; Lymphopenia; Gimap; Diabetes; Bone marrow transplantation;