دانلود مقالات ISI درباره هدف مکانیکی رپامایسین + ترجمه فارسی

Decorin as a multivalent therapeutic agent against cancer

Keywords: هدف مکانیکی رپامایسین; AMPKα; AMP-activated protein kinase, alpha; AP4; Activating enhancer binding protein 4; ATG; Autophagy-related gene; Bcl2; B-cell CLL/lymphoma 2; BRAF; Proto-oncogene B-Raf; ECM; Extracellular matrix; EGFR; Epidermal growth factor receptor; ERK; Extracel

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Polymerase delta-interacting protein 2 regulates collagen accumulation via activation of the Akt/mTOR pathway in vascular smooth muscle cells

Keywords: هدف مکانیکی رپامایسین; Akt; protein kinase B; Atg; autophagy-related gene; ECM; extracellular matrix; 4E-BP1; eukaryotic initiation factor 4E binding protein 1; eIF4E; eukaryotic translation initiation factor 4E; Hsc70; heat shock cognate protein 70; LC3B; microtubule-associate

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه

Xeroderma Pigmentosum Group A Promotes Autophagy to Facilitate Cisplatin Resistance in Melanoma Cells through the Activation of PARP1

Keywords: هدف مکانیکی رپامایسین; DPQ; 3,4-dihydro-5-[4-(1-piperidinyl) butoxy]-1(2H)-isoquinolinone; HMGB1; high-mobility group protein B1; LC3; light chain 3 protein; MC; normal human melanocytes; mTOR; mechanistic target of rapamycin; NER; nucleotide excision repair; PAR; poly(adenosin

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation

Keywords: هدف مکانیکی رپامایسین; 4E-BP1; eukaryotic initiation factor 4E binding protein 1; AMPK; AMP-activated protein kinase; Atg13; autophagy-related 13; FIP200; 200 kilodalton focal adhesion kinase family kinase-interacting protein; GAP; GTPase activator protein; GATOR; GAP activity

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2016 سفارش ترجمه

Autophagy machinery in the context of mammalian mitophagy

Keywords: هدف مکانیکی رپامایسین; PINK1; PTEN-induced putative kinase 1; CCCP; carbonyl cyanide m-chlorophenylhydrazone; OMM; outer mitochondrial membrane; ATG; autophagy-related; ULK1; unc-51 like kinase 1; FIP200; focal adhesion kinase family interacting protein of 200 kDa; mTor; mecha

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Oxidative stress and Treg depletion in lupus patients with anti-phospholipid syndrome

Keywords: هدف مکانیکی رپامایسین; Systemic lupus erythematosus; Anti-phospholipid syndrome; Oxidative stress; Mechanistic target of rapamycin; mTOR; Treg;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Mechanistic Target of Rapamycin (mTOR) in Tuberous Sclerosis Complex-Associated Epilepsy

Keywords: هدف مکانیکی رپامایسین; mTOR inhibitor; tuberous sclerosis complex; epilepsy; epileptogenesis; mechanistic target of rapamycin; mammalian target of rapamycin;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagy and proteins involved in vesicular trafficking

Keywords: هدف مکانیکی رپامایسین; AMD; age-related macular degeneration of the eye; AMPK; AMP-activated protein kinase; ATG; autophagy-related protein; CMA; chaperone-mediated autophagy; COPII; coat protein complex II; DFCP1; double FYVE domain-containing protein 1; EGF; epidermal growth

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Seizure-dependent mTOR activation in 5-HT neurons promotes autism-like behaviors in mice

Keywords: هدف مکانیکی رپامایسین; ASD; autism spectrum disorders; TSC; tuberous sclerosis complex; mTOR; mechanistic target of rapamycin; PTEN; phosphatase and tensin homolog; 5-HT; 5-hydroxytryptophan; SerT/Slc6a4; serotonin transporter; CaMKIIα; Ca2 +/calmodulin-dependent protein kina

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Key role of phosphodiesterase 4A (PDE4A) in autophagy triggered by yessotoxin

Keywords: هدف مکانیکی رپامایسین; AKAP; A-kinase anchoring proteins; Bcl-2; B-cell lymphoma 2 anti-apoptotic protein; BSA; bovine serum albumin; C and R; catalytic and regulatory regions; cAMP; adenosine 3′,5′-cyclic monophosphate; Cav-1; caveolin-1; CREB; cAMP response element bindin

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

mTORC1 Up-Regulates GP73 to Promote Proliferation and Migration of Hepatocellular Carcinoma Cells and Growth of Xenograft Tumors in Mice

Keywords: هدف مکانیکی رپامایسین; Liver Cancer; Mouse Model; Drug; Signal Transduction; DEN; diethylnitrosamine; GP73; Golgi protein 73; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; MEF; mouse embryonic fibroblast; MMP; matrix metalloproteinase; mTOR; mec

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2015 سفارش ترجمه

RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells

Keywords: هدف مکانیکی رپامایسین; 4E-BP1; eukaryotic initiation factor 4E binding protein 1; caRags; constitutively active Rags B and C; caRheb; constitutively active Rheb; caRhoA; constitutively active RhoA; mTOR; mechanistic target of rapamycin; mTORC; mechanistic target of rapamycin co

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Rapamycin Treatment of Healthy Pigs Subjected to Acute Myocardial Ischemia-Reperfusion Injury Attenuates Cardiac Functions and Increases Myocardial Necrosis

Keywords: هدف مکانیکی رپامایسین; AAR; Area at risk; ADP; adenosine diphosphate; AKT; Protein kinase B; ANOVA; Analysis of variance; cTnI; Cardiac troponin I; dP/dT Max; left ventricular maximum contractility; dV/dT max; Left ventricular maximum filling; ECL; Enhanced chemiluminescense; E

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Increasing leucine concentration stimulates mechanistic target of rapamycin signaling and cell growth in C2C12 skeletal muscle cells

Keywords: هدف مکانیکی رپامایسین; Amino acids; Anabolic signaling; C2C12; Skeletal muscle; mTOR; Protein synthesis; ANOVA; analysis of variance; 4E-BP1; eukaryotic initiation factor 4E-binding protein 1; FBS; fetal bovine serum; mTOR; mechanistic target of rapamycin; mTORC1; mechanistic t

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Deficiency of cardiac Acyl-CoA synthetase-1 induces diastolic dysfunction, but pathologic hypertrophy is reversed by rapamycin

Keywords: هدف مکانیکی رپامایسین; Acsl; long-chain acyl-CoA synthetase; FA; fatty acid; mTOR; mechanistic target of rapamycin; mTORC1; mTOR complex-1; MPI; mean performance index; Fatty acid oxidation; mTOR; Insulin resistance; Gene expression; Ventricular function; Substrate switching;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A calpain-cleaved fragment of β-catenin promotes BCRABL1 + cell survival evoked by autophagy induction in response to imatinib

Keywords: هدف مکانیکی رپامایسین; ULK1; unc-51-like kinase; ATG; autophagy-related proteins; FIP200; focal adhesion interacting protein 200; PI3K; class III phosphoinositide 3-kinase; Vps; vacuolar protein sorting; LC3; microtubule-associated protein 1 light chain 3; PE; phosphatidylethan

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Genetics of rare mesenchymal tumors: Implications for targeted treatment in DFSP, ASPS, CCS, GCTB and PEComa

Keywords: هدف مکانیکی رپامایسین; DFSP; dermatofibrosarcoma protuberans; ASPS; alveolar soft part sarcoma; CCS; clear cell sarcoma; GCTB; giant cell tumor of bone; PEComas; perivascular epithelioid cell neoplasm; PDGFRB; platelet-derived growth factor receptor, beta; MET; met proto-oncoge

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR and autophagy: A dynamic relationship governed by nutrients and energy

Keywords: هدف مکانیکی رپامایسین; Akt1; v-akt murine thymoma viral oncogene homolog 1; AMBRA; Autophagy/Beclin-1 regulator 1; AMPK; AMP-dependent protein kinase; ATG; autophagy-related; BECN1; beclin 1; DEPTOR; DEP domain containing mTOR-interacting protein; EGFR; epidermal growth factor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of ERK by sodium tungstate induces protein synthesis and prevents protein degradation in rat L6 myotubes

Keywords: هدف مکانیکی رپامایسین; DEX; dexamethasone; ERK; extracellular signal-regulated kinases 1 and 2; eIF4E; eukaryotic initiation factor E; 4E-BP1; eIF4E-binding protein 1; FoxO; Forkhead box O Family of Transcription Factors; IGF-I; Insulin Growth Factor I; MTOR; mechanistic target

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Transcriptomics profiling and steroid production in mummichog (Fundulus heteroclitus) testes after treatment with 5α-dihydrotestosterone

Keywords: هدف مکانیکی رپامایسین; 11KT; 11-ketotestosterone; ABCC2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; ABCC3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; ABCG8; ATP-binding cassette, sub-family G (WHITE), member 8; ACY1; aminoacylase 1; ADAR; adenosine d

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

eIF4E-Overexpression imparts perillyl alcohol and rapamycin-mediated regulation of telomerase reverse transcriptase

Keywords: هدف مکانیکی رپامایسین; TERT; telomerase reverse transcriptase; mTOR; mechanistic target of rapamycin; S6K; p70 S6 kinase; 4E-BP1; 4E-binding protein 1; eIF4; eukaryotic initiation factor 4; PI3K; phosphoinositide 3-kinase; CHAPS; 3-[(3-Cholamidopropyl)dimethylammonio]-l-propane

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Mechanistic target of rapamycin (mTOR) dependent regulation of thioredoxin interacting protein (TXNIP) transcription in hypoxia

Keywords: هدف مکانیکی رپامایسین; Thioredoxin interacting protein; TXNIP; Mechanistic target of rapamycin; mTOR; Eukaryotic initiation factor 4E binding protein; 4EBP1; Hypoxia; Hypoxia-inducible factor; HIF

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Inflammation, Autophagy, and Obesity: Common Features in the Pathogenesis of Pancreatitis and Pancreatic Cancer

Keywords: هدف مکانیکی رپامایسین; Pancreatic Acinar Cell; Cytokines; Neutrophil; Pancreatic Ductal Adenocarcinoma; K-Ras; AMP; adenosine monophosphate; AP; acute pancreatitis; ATG; autophagy related; Cat; cathepsin; CP; chronic pancreatitis; DAMP; damage/danger-associated molecular patter

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Aspirin Inhibits mTOR Signaling, Activates AMP-Activated Protein Kinase, and Induces Autophagy in Colorectal Cancer Cells

Keywords: هدف مکانیکی رپامایسین; Chemoprevention; Colon Cancer; Oncogene; Tumor Suppressor; ACC; acetyl-CoA carboxylase; ADP; adenosine diphosphate; AMPK; adenosine monophosphate-activated protein kinase; ATP; adenosine triphosphate; CRC; colorectal cancer; eIF4E; eukaryotic translatio

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Deregulated signalling networks in human brain tumours

Keywords: هدف مکانیکی رپامایسین; GBM; glioblastoma multiforme; RTK; receptor tyrosine kinase; EGF(R); epidermal growth factor (receptor); PDGF(R); platelet-derived growth factor (receptor); VEGF(R); vascular endothelial growth factor (receptor); ERBB2; v-erb-b2 erythroblastic leukemia vi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Pharmacodynamic Characterization of the Efficacy Signals Due to Selective BRAF Inhibition with PLX4032 in Malignant Melanoma

Keywords: هدف مکانیکی رپامایسین; AKT; v-akt murine thymoma viral oncogene homolog; ANOVA; analysis of variance; ATCC; American Type Culture Collection; BRAF; v-raf murine sarcoma viral oncogene homolog B1; BRAFm; BRAF mutation; CKIT; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه