Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ANNA; anti-neuronal nuclear antibody; APS; antiphospholipid syndrome; ARHGAP26; Ca/RhoGTPase-activating protein 26; CaMKII; calcium calmodulin-dependent protein kinase II; CASPR2; contactin-asso
مقالات ISI (ترجمه نشده)
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Keywords: CF; climbing fiber; dLGN; dorsal lateral geniculate nucleus; EPSC; excitatory postsynaptic current; IONC; infraorbital nerve cut; KO; knock-out; mGluR1; metabotropic glutamate receptor subtype 1; PC; Purkinje cell; PF; parallel fiber; PrV; principal senso
Keywords: Co-abuse; Ethanol; Nicotine; GLT-1; xCT; mGluR1;
Keywords: MSG; monosodium glutamate; SHR; spontaneously hypertensive rat; BNST; the bed nucleus of the striata; ADHD; attention-deficit hyperactivity disorder; MBP; mean blood pressure; Glu; glutamate; OFT; open-field test; CYT; cylinder test; SIT; social interacti
Keywords: GLT-1; xCT; Cocaine; mGluR1; CPP; Locomotor activity;
Keywords: 2,4-D; dichlorophenoxyacetic acid; [35S]TBPS; [35S]tertiary-butylbicyclophosphorothionate; 3-NP; 3-nitropropionic acid; 4CL; 4-coumarate: CoA ligase; 4-O-MH; 4-O-methylhonokiol; 6-OHDA; 6-hydroxydopamine; 8-oxo-dG; 8-oxo-2â²-deoxyguanosine; AChE; acetylc
G protein-coupled receptor kinases: Past, present and future
Keywords: αN-helix; N-terminal α-helical domain; α2AAR; α2A-adrenergic receptor; AST; active site tether; βAR; β-adrenergic receptor; β2AR; β2-adrenergic receptor; βARK; β-adrenergic receptor kinase; CLBD; C-terminal lipid binding domain; EM; electron mic
Effects of short- and long-term aripiprazole treatment on Group I mGluRs in the nucleus accumbens: Comparison with haloperidol
Keywords: mGluR1; mGluR5; Norbin; Homer1a; Homer1b/c; Ventral striatum; Antipsychotic;
Short-term perception of and conditioned taste aversion to umami taste, and oral expression patterns of umami taste receptors in chickens
Keywords: Umami; T1R1; T1R3; mGluR1; mGluR4; Taste aversion;
Cyclophilin D regulates lifespan and protein expression of aging markers in the brain of mice
Keywords: GFAP; mGluR1; Alpha-synuclein; Permeability transition; Heterozygote; Mitochondria;
Src-family tyrosine kinases and the Ca2Â + signal
Keywords: 5-HT6; serotonin receptor 6; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxylic acid; ADPR; ADP-ribose; AMPA; α-amino-3-hydr
Essential roles of mGluR1 and inhibitory synaptic transmission in NMDA-independent long-term potentiation in the spinal trigeminal interpolaris
Keywords: Spinal trigeminal nucleus interpolaris; Long-term potentiation; Long-term depression; High-frequency stimulation; NMDA receptor-independent; mGluR1
Metabotropic glutamate receptors are involved in the detection of IMP and l-amino acids by mouse taste sensory cells
Keywords: AIDA; (RS)-1-aminoindan-1,5-dicarboxylic acid; Arg; l-arginine; CNQX; cyano-7-nitroquinoxaline-2,3-dione; CPPG; (RS)-α-cyclopropyl-4-phosphonophenylglycine; CTA; conditioned taste aversion; d-AP5; d-(â)-2-amino-5-phosphonopentanoic acid; DHPG; (S)-3,5-
Expressions of multiple umami taste receptors in oral and gastrointestinal tissues, and umami taste synergism in chickens
Keywords: Umami; mGluR1; mGluR4; T1R1; T1R3; Chicken;
Activation of a Temporal Memory in Purkinje Cells by the mGluR7 Receptor
Keywords: classical conditioning; cerebellum; Purkinje cell; timing; temporal; glutamate; mGluR7; mGluR1
[carbonyl-11C]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([11C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate receptor 1 (mGluR1) in monkey brain
Keywords: mGluR1; Radioligand; PET; Carbon-11; Monkey; Brain;
mGluR1 within the nucleus accumbens regulates alcohol intake in mice under limited-access conditions
Keywords: Ethanol; Binge drinking; mGluR1; Nucleus accumbens; Homer2; Phospholipase C;
Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis
Keywords: ALS; amyotrophic lateral sclerosis; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; [3H]d-Asp; [3H]d-aspartate; CAT; catalase; 3,5-DHPG; (S)-3,5-dihydroxyphenylglycine; Gapdh; Glyceraldehyde 3-phosphate dehydrogenase; Glu; glutamate; LTR; long t
Neuroscience Forefront ReviewCajal-Retzius cells: Update on structural and functional properties of these mystic neurons that bridged the 20th century
Keywords: BDNF; brain-derived neurotrophic factor; CRc; Cajal-Retzius cells; Ebf2; early B-cell factor2; ICR; Imprinting Control Region; KCC2; K+-Clâ cotransporter; mGluR1; metabotropic glutamate receptors isoform 1; MZ; marginal zone; RA/PS; retrobulbar area/p
mGluR5 is necessary for maintenance of methamphetamine-induced associative learning
Keywords: Conditioned place preference; Metabotropic glutamate receptor; mGluR5; mGluR1; Rat;
Mechanisms of conotoxin inhibition of N-type (Cav2.2) calcium channels
Keywords: N-type VGCC; neuronal-type voltage-gated calcium channel; CDI; Ca2 +-dependent inactivation; GPCR; G protein-coupled receptor; GABA; γ-aminobutyric acid; GABABR; GABAB receptor; siRNA; small interfering RNA; VFT; Venus flytrap module; nAChR; nicotinic a
3-Phenyl-5-isothiazole carboxamides with potent mGluR1 antagonist activity
Keywords: mGluR1; Receptor occupancy; Formalin model
Basic NeuroscienceMetabotropic glutamate receptor 1 (mGluR1): Antibody specificity and receptor expression in cultured primary neurons
Keywords: Metabotropic glutamate receptors; mGluR1; Neuronal culture; Antibody specificity; Western blot; Immunocytochemistry;
Differential involvement of mGluR1 and mGluR5 in memory reconsolidation and retrieval in a passive avoidance task in 1-day old chicks
Keywords: mGluR1; mGluR5; Memory reconsolidation; Retrieval; Chicks;
Regulation of mGluR1 expression in human melanocytes and melanoma cells
Keywords: Melanoma; mGluR1; NRSF/NRSE; Sp1; Methylation;
Expression of doublecortin, a neuronal migration protein, in unipolar brush cells of the vestibulocerebellum and dorsal cochlear nucleus of the adult rat
Keywords: cerebellar cortex; granule cells; mossy fibers; neurogenesis; plasticity; vestibulocerebellum; CR; calretinin; BSA; bovine serum albumin; DAB; diaminobenzidine; DCN; dorsal cochlear nucleus; DCX; doublecortin; Eps8; epidermal growth factor substrate 8; FL
Characterization of the selective mGluR1 antagonist, JNJ16259685, in rodent models of movement and coordination
Keywords: Metabotropic glutamate receptor; mGluR1; Learning; Motor; Movement; Coordination;
Regulation of group I metabotropic glutamate receptor expression in the rat striatum and prefrontal cortex in response to amphetamine in vivo
Keywords: mGluR1; mGluR5; Dopamine; Stimulant; Cortex; Caudate; Nucleus accumbens; Addiction; Reward
Radiosynthesis and evaluation of [11C]YM-202074 as a PET ligand for imaging the metabotropic glutamate receptor type 1
Keywords: [11C]YM-202074; mGluR1; PET; Autoradiography
Differential distribution of group I metabotropic glutamate receptors in developing human cortex
Keywords: Metabotropic glutamate receptor; Human cortex; Cortical development; Immunocytochemistry; mGluR1; mGluR5
Effect of CFMTI, an allosteric metabotropic glutamate receptor 1 antagonist with antipsychotic activity, on Fos expression in regions of the brain related to schizophrenia
Keywords: metabotropic glutamate receptor; negative allosteric modulator; G protein coupled receptor; c-fos; prefrontal cortex; clozapine; ARC; arcuate hypothalamic nucleus; BCIP; 5-bromo-4-chloro-3-indolyl phosphate; BNST; bed nucleus of the stria terminalis; BSA;
Activation of α1 and α2 noradrenergic receptors exert opposing effects on excitability of main olfactory bulb granule cells
Keywords: norepinephrine; main olfactory bulb; adrenergic receptor; granule cells; GABA; ACSF; artificial cerebrospinal fluid; APV; 2-amino-5-phosphonopentanoic acid; Clon; clonidine; CNQX; 6-cyano-2,3-dihydroxy-7-nitro-quinoxaline; GC; granule cell; GCL; GC layer;
Discovery and biological profile of isoindolinone derivatives as novel metabotropic glutamate receptor 1 antagonists: A potential treatment for psychotic disorders
Keywords: mGluR1; Antagonist; Glutamate; Psychotic disorder
Fluorinated 9H-xanthene-9-carboxylic acid oxazol-2-yl-amides as potent, orally available mGlu1 receptor enhancers
Keywords: Metabotropic glutamate receptor 1; mGluR1; GPCR; Positive allosteric modulator; PAM; Enhancer
Inhibitory effects of Group I metabotropic glutamate receptors antagonists on the expression of NMDA receptor NR1 subunit in morphine tolerant rats
Keywords: CNS; central nervous system; iGluRs; ionotropic glutamate receptors; NMDAR; N-methyl-d-aspartic acid receptor; NR1; NMDA-R1 subunit; mGluRs; metabotropic glutamate receptors; mGluR1; mGlu receptor subtype 1; mGluR5; mGlu receptor subtype 5; AIDA; (RS)-1-A
In vitro and in vivo SAR of pyrido[3,4-d]pyramid-4-ylamine based mGluR1 antagonists
Keywords: mgluR1; Nociceptive pain; Central nervous system
Synergism of virtual screening and medicinal chemistry: Identification and optimization of allosteric antagonists of metabotropic glutamate receptor 1
Keywords: mGluR1; Metabotropic; Antagonist; Self-organizing map; Virtual screening
Age-dependent anticonvulsant action of antagonists of group I glutamate metabotropic receptors in rats
Keywords: Rat; Ontogeny; Pentetrazol; Convulsions; mGluR5; mGluR1
Long-term potentiation of the responses to parallel fiber stimulation in mouse cerebellar cortex in vivo
Keywords: synaptic plasticity; Purkinje cell; metabotropic glutamate receptors; flavoprotein imaging; CF; climbing fiber; DNQX; 6,7-dinitroquinoxaline-2,3-dione disodium salt; LTD; long-term depression; LTP; long-term potentiation; mGluR1; metabotropic glutamate re
Activity-dependent plasticity of developing climbing fiber-Purkinje cell synapses
Keywords: cerebellum; development; synapse elimination; axonal competition; synaptic plasticity; parallel fiber; E; embryonic day; EPSC; excitatory postsynaptic current; GluRδ2; glutamate receptor type δ2; LTD; long-term depression; LTP; long-term potentiation; m
Src-family protein tyrosine kinase negatively regulates cerebellar long-term depression
Keywords: Purkinje neuron; Cerebellum; Synaptic plasticity; LTD; Src-family protein tyrosine kinase; mGluR1;
Inhibition of mGluR1 and IP3Rs impairs long-term memory formation in young chicks
Keywords: Inositol (1,4,5)-trisphosphate receptor; Metabotropic glutamate receptor; mGluR1; Calcium; Intracellular calcium stores; Learning; Memory; Chick
Effects of subtype-selective group I mGluR antagonists on synchronous activity induced by 4-aminopyridine/CGP 55845 in adult guinea pig hippocampal slices
Keywords: GABA; mGluR1; mGluR5; Metabotropic glutamate receptor; Electrophysiology
Allosteric potentiators of metabotropic glutamate receptor subtype 1a differentially modulate independent signaling pathways in baby hamster kidney cells
Keywords: mGluR1; Allosteric potentiator; Glutamate; Ligand-induced differential signalingmGluR, metabotropic glutamate receptor; GPCR, G protein-coupled receptor; ERK, extracellular signal-regulated kinase; Ro 67-7476, (S)-2-(4-fluorophenyl)-1-(toluene-4-sulfonyl)
3D-QSAR studies of triazafluorenone inhibitors of metabotropic glutamate receptor subtype 1
Keywords: 3D-QSAR; MFA; RSA; mGluR1; Triazafluorenone inhibitors
Spontaneous activity in Purkinje cells: Multi-electrode recording from organotypic cerebellar slice cultures
Keywords: MED recording; Potassium channels; cGMP; Phosphodiesterase inhibitor; Guanylate cyclase activator; mGluR1
13C bis-labeled pyrroles: A tool for the identification of the rat metabolism of 3-methyl pyrrole-2,4-dicarboxylic acid 2-propyl ester 4-(1,2,2-trimethyl-propyl) ester
Keywords: mGluR1; Metabotropic; Glutamate; Metabolism
mGluR1 in the fundic glands of rat stomach
Keywords: Stomach; mGluR1; l-glutamate; Chief cells; Pepsinogen C; Protein digestion
Structure–activity relationships of novel non-competitive mGluR1 antagonists: A potential treatment for chronic pain
Keywords: mGluR; mGluR1; CNS; Chronic pain; Library; Quinoxaline; Pyrazine; c log P; log D; Metabolism