Keywords: دستگیری متیوتیک; Diallyl sulfide; Mitotic arrest; Cell death; Autophagic flux; Zebrafish xenografts; Baf; bafilomycin A1; BRAF; v-Raf murine sarcoma viral oncogene homolog B; CFAs; colony formation assays; CHCA; α-cyano-4-hydroxy-cinnamic acid; CHX; cycloheximide; CIMP;
مقالات ISI دستگیری متیوتیک (ترجمه نشده)
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Keywords: دستگیری متیوتیک; Senescence; Curcumin; Mitotic arrest; DNA damage; Cancer;
Keywords: دستگیری متیوتیک; Germ cells; Embryonic gonad; Differentiation; Meiosis; Mitotic arrest; Pluripotency; Mouse;
Keywords: دستگیری متیوتیک; Polo-like kinase 1; Cell cycle; Mitotic arrest; Slippage;
Keywords: دستگیری متیوتیک; Bcl-2 proteins; Apoptosis; Cancer cell lines; Mitotic arrest; Mitotic death; Phosphorylation;
Keywords: دستگیری متیوتیک; Sulforaphane; ROS; Mitotic arrest; Apoptosis; 5637 Cells;
PMN inhibits colorectal cancer cells through inducing mitotic arrest and p53-dependent apoptosis via the inhibition of tubulin polymerization
Keywords: دستگیری متیوتیک; PMN; Colorectal cancer; Mitotic arrest; Microtubule; Apoptosis; p53;
The small molecule CS1 inhibits mitosis and sister chromatid resolution in HeLa cells
Keywords: دستگیری متیوتیک; CS1; Mitotic arrest; Spindle assembly checkpoint; Sister chromatid resolution; Microtubule inhibitor; Histone phosphorylation;
Heterocyclic organobismuth (III) compounds containing an eight-membered ring: Inhibitory effects on cell cycle progression
Keywords: دستگیری متیوتیک; Heterocyclic organobismuth compounds; Mitotic arrest; Spindle checkpoint; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco's Modified Eagle Medium; EGTA; ethylene glycol-bis(β-aminoethyl ether)-N,N,Nâ²,Nâ²-tetraacetic acid; MTOC; microtubule-organ
Diallyl trisulfide induces apoptosis and mitotic arrest in AGS human gastric carcinoma cells through reactive oxygen species-mediated activation of AMP-activated protein kinase
Keywords: دستگیری متیوتیک; DATS; Apoptosis; Mitotic arrest; ROS; AMPK;
Oxidative stress induces mitotic arrest by inhibiting Aurora A-involved mitotic spindle formation
Keywords: دستگیری متیوتیک; CIN; chromosomal instability; CKIs; CDK inhibitors; DDC; sodium diethyldithiocarbamate trihydrate; GSK-3; glycogen synthase kinase 3; NAC; N-acetyl-L-cysteine; PCM; pericentriolar material; PCNT; pericentrin; ROS; reactive oxygen species; SAC; spindle ass
Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts
Keywords: دستگیری متیوتیک; Pancreatic cancer; Mitotic arrest; DNA damage; Apoptosis; c-Jun N-terminal kinase; Trichodermin; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma extra long; CDK; cyclin-dependent kinase; Cdc; cell division cycle; DSBs; double-strand breaks; DUSP1; dual
Pseudolaric acid B induces mitotic arrest and apoptosis in both 5-fluorouracil-sensitive and -resistant colorectal cancer cells
Keywords: دستگیری متیوتیک; Pseudolaric acid B; Colorectal cancer; 5-FU resistance; Mitotic arrest; Apoptosis; Spindle;
Significant decrease of ADP release rate underlies the potent activity of dimethylenastron to inhibit mitotic kinesin Eg5 and cancer cell proliferation
Keywords: دستگیری متیوتیک; Eg5 inhibitor; Mitotic arrest; Apoptosis; ATPase activity; ADP release;
Podoverine A—a novel microtubule destabilizing natural product from the Podophyllum species
Keywords: دستگیری متیوتیک; XSSBSQHRXYWXSZ-UHFFFAOYSA-N; XSSBSQHRXYWXSZ-UHFFFAOYSA-N; VCKYLOIMXUHPDA-UHFFFAOYSA-NNatural products; High content screening; Mitotic arrest; Vinca binding site
Depletion of IK causes mitotic arrest through aberrant regulation of mitotic kinases and phosphatases
Keywords: دستگیری متیوتیک; PARP; poly ADP ribose polymerase; PLK1; polo-like kinase 1; PP1; protein phosphatase 1; PP2A; protein phosphatase 2A; PP6; protein phosphatase 6; Aurora A; CDK1; IK; Mitotic arrest; Protein phosphatase;
Evaluation of 2â²,4â²-dihydroxy-3,4,5-trimethoxychalcone as antimitotic agent that induces mitotic catastrophe in MCF-7 breast cancer cells
Keywords: دستگیری متیوتیک; 2â²,4â²-Dihydroxy-3,4,5-trimethoxychalcone; Mitotic arrest; Anti-microtubule; Mitotic catastrophe; Apoptosis; Cancer chemotherapy;
Pterocarpans induce tumor cell death through persistent mitotic arrest during prometaphase
Keywords: دستگیری متیوتیک; Pterocarpan; Cell cycle; Mitotic arrest; Breast cancer cell lines; Apoptosis
Thymoquinone inhibits microtubule polymerization by tubulin binding and causes mitotic arrest following apoptosis in A549 cells
Keywords: دستگیری متیوتیک; Thymoquinone; MT polymerization inhibition; Mitotic arrest; Apoptosis; Cancer therapy; TQ; thymoqionone; ROS; reactive oxygen species; PIPES; 1,4-piperazinediethanesulfonic acid; EGTA; ethylene bis(oxyethylenenitrilo) tetraacetic acid; DMSO; dimethyl sulf
NEK9 depletion induces catastrophic mitosis by impairment of mitotic checkpoint control and spindle dynamics
Keywords: دستگیری متیوتیک; NEK9; Cytokinesis; Checkpoint system; Mitotic arrest; Therapeutic target;
Molecular mechanisms of the antitumor activity of SB225002: A novel microtubule inhibitor
Keywords: دستگیری متیوتیک; SB; SB225002; IL-8RB; IL-8 receptor B; MDR; multidrug resistance; MAPK; mitogen-activated protein kinase; SB225002; Mitotic arrest; Microtubule destabilizer; Vinblastine-binding site; BAK; Mitochondrial apoptosis; p38 MAPK;
Resonance versus linear responses to alternating electric fields induce mechanistically distinct mammalian cell death
Keywords: دستگیری متیوتیک; Bioelectric effect; Cell death dynamics; Apoptosis; Mitotic arrest; Live-cell imaging
TW01001, a novel piperazinedione compound, induces mitotic arrest and autophagy in non-small cell lung cancer A549 cells
Keywords: دستگیری متیوتیک; Autophagy; Apoptosis; Mitotic arrest; Signal transduction; Lung cancer
Inhibition of AKT enhances mitotic cell apoptosis induced by arsenic trioxide
Keywords: دستگیری متیوتیک; Arsenic trioxide; AKT; Mitotic arrest; Spindle abnormalities; Apoptosis
2-(3-Methoxyphenyl)-5-methyl-1,8-naphthyridin-4(1H)-one (HKL-1) induces G2/M arrest and mitotic catastrophe in human leukemia HL-60 cells
Keywords: دستگیری متیوتیک; 2-(3-Methoxyphenyl)-5-methyl-1,8-naphthyridin-4(1H)-one (HKL-1); 2-Phenyl-1,8-naphthyridin-4-one (2-PN); HL-60; Mitotic arrest; Mitotic catastrophe; Apoptosis
Protopine, a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines
Keywords: دستگیری متیوتیک; Protopine; Microtubules; Mitotic arrest; Cdk1; Apoptosis
Vinca alkaloids cause aberrant ROS-mediated JNK activation, Mcl-1 downregulation, DNA damage, mitochondrial dysfunction, and apoptosis in lung adenocarcinoma cells
Keywords: دستگیری متیوتیک; Vinca alkaloids; Lung adenocarcinoma; Mitotic arrest; Apoptosis; ROS; JNK; Mcl-1; Mitochondria; Caspase
A modular approach to trim cellular targets in anticancer drug discovery
Keywords: دستگیری متیوتیک; Phenotypic Drug Discovery; Antitumor agents; Cell cycle; Mitotic arrest; Structure–activity relationships
Induction of cell cycle arrest and DNA damage by the HDAC inhibitor panobinostat (LBH589) and the lipid peroxidation end product 4-hydroxynonenal in prostate cancer cells
Keywords: دستگیری متیوتیک; Prostate cancer; Panobinostat; HNE; Mitotic arrest; DNA damage; Androgen receptor; Free radicals
Airborne urban particles (Milan winter-PM2.5) cause mitotic arrest and cell death: Effects on DNA, mitochondria, AhR binding and spindle organization
Keywords: دستگیری متیوتیک; Particulate matter; DNA-damage; Mitotic arrest; Cell death; Apoptosis
Nocodazole induces mitotic cell death with apoptotic-like features in Saccharomyces cerevisiae
Keywords: دستگیری متیوتیک; ROS; reactive oxygen species; APC/C; anaphase-promoting complex/cyclosome; SAC; spindle assembly checkpoint; PI; propidium iodide; TUNEL; terminal deoxynucleotidyl transferase-mediated dUTP nick-end-labeling; GFP; green fluorescent protein; Budding yeast;
Arecoline arrests cells at prometaphase by deregulating mitotic spindle assembly and spindle assembly checkpoint: Implication for carcinogenesis
Keywords: دستگیری متیوتیک; Arecoline; Betel quid; Chromosomal aberrations; Genomic instability; Mitotic arrest; Spindle assembly checkpoint
Mouse germ cell development: From specification to sex determination
Keywords: دستگیری متیوتیک; Germ cell; Gonad; Specification; Migration; Proliferation; Epigenetics; Differentiation; Meiosis; Mitotic arrest
Synthesis and activity evaluation of phenylurea derivatives as potent antitumor agents
Keywords: دستگیری متیوتیک; Phenylurea; Anticancer; Structure–activity relationship; Tubulin; Mitotic arrest
Heat shock protein inhibitors, 17-DMAG and KNK437, enhance arsenic trioxide-induced mitotic apoptosis
Keywords: دستگیری متیوتیک; Arsenic trioxide; Heat shock proteins; Mitotic arrest; Apoptosis
Combination treatment with arsenic trioxide and irradiation enhances apoptotic effects in U937 cells through increased mitotic arrest and ROS generation
Keywords: دستگیری متیوتیک; Arsenic trioxide; Mitotic arrest; Apoptosis; Irradiation; Leukemia;
Screening of anti-glioma effects induced by sigma-1 receptor ligands: Potential new use for old anti-psychiatric medicines
Keywords: دستگیری متیوتیک; Cell migration; Cell proliferation; Chemotherapy; Donepezil; Glioblastoma; Mitotic arrest; Sigma receptors
Mitotic arrest-associated apoptosis induced by sodium arsenite in A375 melanoma cells is BUBR1-dependent
Keywords: دستگیری متیوتیک; Arsenite; Mitotic arrest; Apoptosis; Spindle checkpoint
Carbamazepine induces mitotic arrest in mammalian Vero cells
Keywords: دستگیری متیوتیک; Carbamazepine; Vero cells; Mitotic arrest; Monopolar spindle; Apoptosis
Sensitivity to sodium arsenite in human melanoma cells depends upon susceptibility to arsenite-induced mitotic arrest
Keywords: دستگیری متیوتیک; Arsenite; Mitotic arrest; Apoptosis; Spindle checkpoint
KRIBB3, a novel microtubule inhibitor, induces mitotic arrest and apoptosis in human cancer cells
Keywords: دستگیری متیوتیک; Isoxazole; Microtubule inhibitor; Mitotic arrest; Apoptosis; Bax activation; Cancer therapy
Synthesis and evaluation of substituted benzoisoquinolinones as potent inhibitors of Chk1 kinase
Keywords: دستگیری متیوتیک; Chk1 kinase; Chek1 kinase; Kinases; Photochemistry; Benzoisoquinolinones; PSA; DNA damaging agents; Mitotic arrest; Checkpoint escape; p53-Deficient cancer; Cancer; Apoptosis
Sulforaphane suppresses angiogenesis and disrupts endothelial mitotic progression and microtubule polymerization
Keywords: دستگیری متیوتیک; Sulforaphane; Angiogenesis; Mitotic arrest; Microtubules
NuSAP is degraded by APC/C–Cdh1 and its overexpression results in mitotic arrest dependent of its microtubules' affinity
Keywords: دستگیری متیوتیک; APC/C, anaphase promoting complex/cyclosome; MT, Microtubule; NuSAP, nucleolar and spindle-associated protein; RNAi, RNA interferenceNuSAP; APC/C; Mitotic arrest; Degradation
Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways
Keywords: دستگیری متیوتیک; Quinolone; Mitotic arrest; Cdk1; Bcl-2 family of proteins; Caspase; AIF
Paclitaxel suppresses the growth of primary prostate tumours (RM-1) and metastases in the lung in C57BL/6 mice
Keywords: دستگیری متیوتیک; Paclitaxel; Prostate cancer; Mouse model; Cell apoptosis; Mitotic arrest
Phenothiazine and carbazole-related compounds inhibit mitotic kinesin Eg5 and trigger apoptosis in transformed culture cells
Keywords: دستگیری متیوتیک; Phenothiazine; Mitotic arrest; Apoptosis; Eg5
Synthesis of microtubule-interfering halogenated noscapine analogs that perturb mitosis in cancer cells followed by cell death
Keywords: دستگیری متیوتیک; Cell cycle; Mitotic arrest; Anticancer; Tubulin-binding