Keywords: AIS; Abbreviated Injury Scale; AKI; acute kidney injury; aPTT; activated partial thromboplastin time; CC16; Clara Cell Protein 16; DAMP; danger-associated molecule pattern; GCS; Glasgow Coma Scale; HS; hemorrhagic shock; I-FABP; liver â/intestinal-type
مقالات ISI (ترجمه نشده)
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Keywords: AMOP; adhesion-associated domain present in MUC4 and other proteins; C4BP; C4b-binding protein; CCP; complement control protein; CR1; complement receptor 1; CR3; complement receptor 3; CS; chondroitin sulfate; CSMD; CUB and Sushi multiple domains; DAF; de
Keywords: MMPs; Matrix metalloproteinases; ECM; extracellular matrix; TSP-2; Thrombospondin-2; FAK; focal adhesion kinase; Akt; protein kinase B; NF-κB; nuclear factor kappa B; Ig; immunoglobulin; DN; dominant negative; shRNA; short hairpin RNA; TCGA; The Cancer G
Keywords: Photobiomodulation; LLLT; Periodontal ligament; RANKL; MMP-13; Epithelial hyperplasia;
Keywords: Osteoarthritis (OA); Type II collagen; MMP-1; MMP-13; Oxytocin;
Keywords: XLH; Pregnancy; Lactation; Carbonate; Phosphate; Cortical bone remodeling; Vitamin D; Osteoporosis; Mineral metabolism; MMP-13
Keywords: Cerebral ischemia; MMP-13; Angiogenesis; Neurorepair; Neurogenesis;
Keywords: Basal cell carcinoma; MMP-1; MMP-2; MMP-9; MMP-13; E-cadherin
The cysteinyl leukotriene receptor 1 (CysLT1R) antagonist montelukast suppresses matrix metalloproteinase-13 expression induced by lipopolysaccharide
Keywords: Osteoblast; LPS; MMP-13; Montelukast;
Colorectal signet ring cell carcinoma: Influence of EGFR, E-cadherin and MMP-13 expression on clinicopathological features and prognosis
Keywords: Colorectal signet ring carcinoma; EGFR; E-cadherin; MMP-13; Prognosis;
Aqueous extract of Codium fragile alleviates osteoarthritis through the MAPK/NF-κB pathways in IL-1β-induced rat primary chondrocytes and a rat osteoarthritis model
Keywords: Osteoarthritis; Codium fragile (Suringar) Hariot; Nitric oxide; MMP-13; ADAMTS-4; ADAMTS-5; MAPKs; NF-κB;
PKR activation causes inflammation and MMP-13 secretion in human degenerated articular chondrocytes
Keywords: Osteoarthritis; Human chondrocyte; PKR; Oxidative stress; MMP-13;
Role of the serotonergic pathway in uterotonic activity of Ananas comosus (L.) Merr. - An in vitro and in vivo study
Keywords: Ananas comosus; Uterine contraction; MMP-13; Intrauterine pressure; Serotonin; F4; fraction 4; p-ERK1/2; phospho-extracellular signal-regulated kinase1/2; MMP-13; matrix metallopeptidase 13, 5-HT, 5-hydroxytryptamine; E; embryonic age; IUP; intrauterine
Oxidative stress-dependent MMP-13 activity underlies glucose neurotoxicity
Keywords: Glucose; Neuropathy; Epidermis; Mice; ROS; MMP-13;
Glucocorticoids induce apoptosis and matrix metalloproteinase-13 expression in chondrocytes through the NOX4/ROS/p38 MAPK pathway
Keywords: Dex; dexamethasone; ROS; reactive oxygen species; NOX; NADPH oxidase; MAPK; mitogen-activated protein kinase; MMP; metalloproteinase; GCs; glucocorticoids; GR; glucocorticoid receptor; OA; osteoarthritis; RA; rheumatoid arthritis; NADPH; nicotinamide aden
MiR-26a and miR-26b mediate osteoarthritis progression by targeting FUT4 via NF-κB signaling pathway
Keywords: 3â²UTR; 3â²untranslated region; OA; osteoarthritis; miRNAs; microRNAs; ECM; extracellular matrix; siRNA; small interfering RNA; PBS; phosphate-buffered saline; BSA; bovine serum albumin; FUT4; alpha-1, 6 fucosyltransferase 4; MMP-13; matrix metalloprote
l-Carnitine ameliorates knee lesions in mono-iodoacetate induced osteoarthritis in rats
Keywords: l-Carnitine; Glucosamine; MMP-13; Osteoarthritis; IL-1β; COMP;
Transforming growth factor-β1 regulation of ATF-3, c-Jun and JunB proteins for activation of matrix metalloproteinase-13 gene in human breast cancer cells
Keywords: ATF-3; TGF-β1; MMP-13; c-Jun; JunB; Breast cancer;
A standardized extract of Butea monosperma (Lam.) flowers suppresses the IL-1β-induced expression of IL-6 and matrix-metalloproteases by activating autophagy in human osteoarthritis chondrocytes
Keywords: OA; osteoarthritis; BME; extract preparation of Butea monosperma (Lam.) flowers; IL-6; interleukin-6; MMP-3; matrix metalloprotease-3; MMP-9; matrix metalloprotease-9; MMP-13; matrix metalloprotease-13; LC3-I; microtubule associated protein 1 light chain
The vacuolar H+ ATPase V0 subunit d2 is associated with chondrocyte hypertrophy and supports chondrocyte differentiation
Keywords: Chondrocyte; Hypertrophy; Endochondral ossification; ATP6V0D2; Vacuolar H+-ATPase; ABH; alcian blue/haematoxylin/eosin/acid fuchsin stain; ATP6V0D2; vacuolar H+ ATPase V0 subunit d2; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified Eagle's
Dopamine D2 receptor suppresses gastric cancer cell invasion and migration via inhibition of EGFR/AKT/MMP-13 pathway
Keywords: Dopamine D2 receptor; Gastric cancer; Invasion; EGFR; AKT; MMP-13
MiR-502-5p inhibits IL-1β-induced chondrocyte injury by targeting TRAF2
Keywords: OA; osteoarthritis; miR-502-5p; microRNA-502-5p; IL-1β; interleukin -1 beta; TNFα; tumor necrosis factor alpha; TNFR; tumor necrosis factor receptor; TRAF2; TNF receptor-associated factor 2; ECM; extracellular matrix; MMP-13; matrix metalloproteinase-13
Design, synthesis, and biological activity of novel, potent, and highly selective fused pyrimidine-2-carboxamide-4-one-based matrix metalloproteinase (MMP)-13 zinc-binding inhibitors
Keywords: Matrix metalloproteinase; MMP-13; Fused pyrimidine-2-carboxamide; Zinc-binding group; Structure-based drug design; Osteoarthritis;
Edaravone suppresses degradation of type II collagen
Keywords: Osteoarthritis (OA); Type â
¡; Collagen; Edaravone; IRF-1; MMP-13;
Nanodrugs to target articular cartilage: An emerging platform for osteoarthritis therapy
Keywords: Ab; antibody; ACL; anterior cruciate ligament; ADAMTS-4; a disintegrin and metalloproteinase with thrombospondin motifs 4; ADAMTS-5; a disintegrin and metalloproteinase with thrombospondin motifs 5; AGE; advanced glycation end product; AIA; antigen induce
Effect of low intensity pulsed ultrasound on expression of TIMP-2 in serum and expression of mmp-13 in articular cartilage of rabbits with knee osteoarthritis
Keywords: Low intensity pulsed ultrasound; Osteoarthritis; TIMP-2; MMP-13
Protease-activated receptor 2 enhances renal cell carcinoma cell invasion and migration via PI3K/AKT signaling pathway
Keywords: PAR-2; Renal cell carcinoma; Invasion; PI3K/AKT pathway; MMP-13; uPA;
MicroRNA-146a reduces IL-1 dependent inflammatory responses in the intervertebral disc
Keywords: ADAMTS; a disintergrin and metalloproteinase with thrombospondin motifs; ANOVA; analysis of variance; COX-2; cyclooxygenase-2; Ct; threshold cycle; DAB; 3, 3â²-diaminobenzidine; DMEM; Dulbecco's modified eagle medium; IHC; immunohistochemical; EGFR; epid
MicroRNA-222 regulates MMP-13 via targeting HDAC-4 during osteoarthritis pathogenesis
Keywords: miR-222; HDAC-4; MMP-13; Apoptosis; Human chondrocytes; OA chondrocytes
The protective effects of Donepezil (DP) against cartilage matrix destruction induced by TNF-α
Keywords: Osteoarthritis; Donepezil; TNF-α; MMP-13; Collagen type II;
Cilostazol prevents the degradation of collagen Type II in human chondrocytes
Keywords: Cilostazol; Osteoarthritis (OA); Collagen type II; MMP-13; IRF-1; STAT1
MiR-126-5p regulates osteoclast differentiation and bone resorption in giant cell tumor through inhibition of MMP-13
Keywords: MMP-13; GCT; MiR-126-5p; Osteolysis; Osteoclast differentiation;
In vivo imaging of MMP-13 activity in the murine destabilised medial meniscus surgical model of osteoarthritis
Keywords: Osteoarthritis; MMP-13; Imaging;
Epiphyseal abnormalities, trabecular bone loss and articular chondrocyte hypertrophy develop in the long bones of postnatal Ext1-deficient mice
Keywords: HS; heparan sulfate; BMP; bone morphogenetic protein; FGF; fibroblast growth factor; HSPGs; heparan sulfate proteoglycans; Ihh; Indian hedgehog; HME; Hereditary Multiple Exostoses; MMP-13; matrix metalloprotease 13; VEGFs; vascular endothelial growth fact
Potent inhibitors precise to S1â² loop of MMP-13, a crucial target for osteoarthritis
Keywords: MMP-13; Pharmacophore; Docking; QSAR; Zinc database; E-model energies;
Differential expression of matrix metalloproteinase-13 in mucinous and nonmucinous colorectal carcinomas
Keywords: MMP-13; Mucinous; Nonmucinous; Colorectal; Carcinoma; Microarray
T cells stimulate catabolic gene expression by the stromal cells from giant cell tumor of bone
Keywords: Giant cell tumor; CD40; CD40L; PTHrP; MMP-13; RANKL;
N-O-Isopropyl sulfonamido-based hydroxamates: Kinetic characterisation of a series of MMP-12/MMP-13 dual target inhibitors
Keywords: Enzyme kinetics; Matrix metalloproteinase; Slow-binding inhibition; Rheumatoid arthritis; MMP-13; MMP-12;
Hyaluronan regulates PPARγ and inflammatory responses in IL-1β-stimulated human chondrosarcoma cells, a model for osteoarthritis
Keywords: MMP-1; matrix metalloproteinase 1; MMP-13; matrix metalloproteinase 13; ECM; extracellular matrix; HMW-HA; high-molecular-weight hyaluronan; oligo-HA; oligomer hyaluronan; OA; osteoarthritis; COX-2; cyclooxygenase-2; PPARγ; peroxisome proliferator-activa
Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage
Keywords: Ihh; Cartilage; Osteoarthritis; Chondrocyte hypertrophy; MMP-13
Osteoarthritis-like changes in the heterozygous sedc mouse associated with the HtrA1–Ddr2–Mmp-13 degradative pathway: a new model of osteoarthritis
Keywords: Spondyloepiphyseal dysplasia congenita; Cartilage degradation; HtrA1; Ddr2; Mmp-13; Osteoarthritis; Type II collagen mutation
Continued exploration of biphenylsulfonamide scaffold as a platform for aggrecanase-1 inhibition
Keywords: Aggrecanase-1; MMP-13; Osteoarthritis; Biphenylsulfonamide
The design and synthesis of novel N-hydroxyformamide inhibitors of ADAM-TS4 for the treatment of osteoarthritis
Keywords: ADAM-TS4; MMP-13; Reverse hydroxamates; Aggrecanases; Osteoarthritis; Cyp inhibition
TGF-β signaling plays an essential role in the growth and maintenance of intervertebral disc tissue
Keywords: TGF-β; Col2a1-CreERT2; Intervertebral disc; Conditional knockout; MMP-13
SAR studies of non-zinc-chelating MMP-13 inhibitors: Improving selectivity and metabolic stability
Keywords: MMP-13; Non-Zn-chelating inhibitor; SAR; Selectivity; Metabolic stability
Bone Morphogenetic Proteins and articular cartilage: To serve and protect or a wolf in sheep clothing’s?
Keywords: Osteoarthritis; BMPs; MMP-13; Chondrocyte differentiation
Protein geranylgeranylation controls collagenase expression in osteoarthritic cartilage
Keywords: Statin; Simvastatin; Geranylgeranylation; Chondrocyte; Collagenase; MMP-13
Identification and characterization of matrix metalloproteinase-13 sequence structure and expression during embryogenesis and infection in channel catfish (Ictalurus punctatus)
Keywords: Extracellular matrix; Metalloproteinase; Catfish; Matrix metalloproteinase-13; MMP-13; Collagenase-3; Embryogenesis; Edwardsiella ictaluri
Research ArticleThe NF-κB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes
Keywords: HDAC; histone acetyltransferase; MMP; matrix metalloproteinase; CCl4; carbon tetrachloride; ChIP; chromatin immunoprecipitation; MAP3K; MAP kinase kinase kinase; IκB; inhibitor of kappa B; p50 NF-κB; HDAC-1; Inflammation; MMP-13; GM-CSF; CXCL10; CCL2; C
SHP-1, a novel peptide isolated from seahorse inhibits collagen release through the suppression of collagenases 1 and 3, nitric oxide products regulated by NF-κB/p38 kinase
Keywords: SHP-1; Collagen; Arthritis; MMP-1; MMP-13; NO; NF-κB/p38 kinase;