دانلود مقالات ISI درباره حالت عمل + ترجمه فارسی

Synthesis and mode of action studies of N-[(-)-jasmonyl]-S-tyrosin and ester seiridin jasmonate

Keywords: حالت عمل; Jasmonic acid; Jasmonate amides/ester synthesis; JA-Tyr and JA-Sei; Mode of action;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

A simple method for measuring immune complex-mediated, Fc gamma receptor dependent antigen-specific activation of primary human T cells

Keywords: حالت عمل; IVIg; Intravenous Immunoglobulin; IC; immune complex; TT; tetanus toxoid; FcγR; Fc gamma receptor; APC; antigen presenting cell; PBMC; peripheral blood mononuclear cells; DC; dendritic cell; MOA; mode of action; CTV; CellTrace Violet; IFN-γ; Interferon-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Toxicity of contaminants of emerging concern to Dugesia japonica: QSTR modeling and toxicity relationship with Daphnia magna

Keywords: حالت عمل; AD; applicability domain; CEC; contaminants of emerging concern; CEFIC; European Chemical Industry Council; EDCs; endocrine disrupting chemicals; GA; genetic algorithm; HPV; high production volume according to OECD; ICE; interspecies correlation estimatio

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular and biological characterization of Sclerotinia sclerotiorum resistant to the anilinopyrimidine fungicide cyprodinil

Keywords: حالت عمل; Cyprodinil; Sclerotinia sclerotiorum; Mode of action; Resistance risk;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Mode of action characterization for adverse effect of propranolol in Daphnia magna based on behavior and physiology monitoring and metabolite profiling

Keywords: حالت عمل; Propranolol; Metabolites; Mode of action; Daphnia magna;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Utilizing Threshold of Toxicological Concern (TTC) with high throughput exposure predictions (HTE) as a risk-based prioritization approach for thousands of chemicals

Keywords: حالت عمل; AOPs; Adverse Outcome Pathways; FSANZ; Food Standards Australia New Zealand; HTE; High Throughput Exposure; HTS; high throughput screening; ILSI; International Life Sciences Institute; HESI; Health and Environmental Sciences Institute; RISK21; Risk Assess

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

A review of the genotoxicity of trimethylolpropane triacrylate (TMPTA)

Keywords: حالت عمل; TMPTA; Trimethylolpropane triacrylate; MoA; mode of action; MN; micronucleus or micronuclei; CA; chromosomal aberrations; MI; mitotic index; MTD; maximum tolerated dose, i.v. intravenous; MLA; mouse lymphoma assay; HPGRT; Hypoxanthine-guanine phosphoribos

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Linking mode of action of the model respiratory and photosynthesis uncoupler 3,5-dichlorophenol to adverse outcomes in Lemna minor

Keywords: حالت عمل; Lemna minor; 3,5-dichlorophenol; Reactive oxygen species; Growth; PSII; Lipid peroxidation; Oxidative phosphorylation; Mode of action; Adverse outcome pathway;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Whole genome mRNA transcriptomics analysis reveals different modes of action of the diarrheic shellfish poisons okadaic acid and dinophysis toxin-1 versus azaspiracid-1 in Caco-2 cells

Keywords: حالت عمل; Okadaic acid; Dinophysis toxin-1; Azaspiracid-1; Mode of action; Transcriptomics; Caco-2 cells;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Toxicogenomics of the flame retardant tris (2-butoxyethyl) phosphate in HepG2 cells using RNA-seq

Keywords: حالت عمل; Tris (2-butoxyethyl) phosphate; HepG2; RNA-seq; Toxicogenomics; Mode of action;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of carbamazepine and cetirizine under an ocean acidification scenario on the biochemical and transcriptome responses of the clam Ruditapes philippinarum

Keywords: حالت عمل; Pharmaceuticals; Mode of action; Biomarkers; Transcriptomic; Bivalves;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

A human relevance investigation of PPARα-mediated key events in the hepatocarcinogenic mode of action of propaquizafop in rats

Keywords: حالت عمل; Propaquizafop; Carcinogenicity; Rodent hepatocarcinogenesis; PPARα; Liver; Peroxisome proliferators; Mode of action; Human relevance framework; Enzyme induction; Rats; ACO; Acyl-CoA oxidase; bw; body weight; BrdU; bromodeoxyuridine; CAT; catalase; CYP; c

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Regulatory identification of BPA as an endocrine disruptor: Context and methodology

Keywords: حالت عمل; Bisphenol A; Endocrine disruption; ED; SVHC; Substance of very high concern; REACh; ANSES; Agence Nationale de Sécurité Sanitaire de l'alimentation, de l'environnement et du travail (French Agency for Food, Environmental and Occupational Health & Sa

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Minimum datasets to establish a CAR-mediated mode of action for rodent liver tumors

Keywords: حالت عمل; CAR; Constitutive androstane receptor; Nitrapyrin; Metofluthrin; Rodent; Liver; Tumor; Mode of action; Minimal dataset; AOP; Adverse Outcome Pathway; AE; associative events; BrdU; 5-bromo-2′-deoxyuridine; BROD; benzyloxyresorufin-O-debenzylation; BQ; be

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Effect-based trigger values for in vitro and in vivo bioassays performed on surface water extracts supporting the environmental quality standards (EQS) of the European Water Framework Directive

Keywords: حالت عمل; AA-EQS; average annual environmental quality standard; ACR; acute-to-chronic ratio; AhR; arylhydrocarbon receptor; AR; androgen receptor; AWTP; advanced water treatment plant; BEQ; bioanalytical equivalent concentration; DWTP; drinking water treatment pla

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Primary evidence of the mechanisms of action of HIV aspartyl peptidase inhibitors on Trypanosoma cruzi trypomastigote forms

Keywords: حالت عمل; Trypanosoma cruzi; HIV-PIs; Mode of action; Physiological alterations;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Characterization of essential oil from Ocimum gratissimum leaves: Antibacterial and mode of action against selected gastroenteritis pathogens

Keywords: حالت عمل; Ocimum gratissimum; Gastroenteritis; Membrane disruption; Mode of action; Fast killing effect;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

A chitin deacetylase of Podospora anserina has two functional chitin binding domains and a unique mode of action

Keywords: حالت عمل; CDA; chitin deacetylase; DP; degree of polymerization; DA; degree of acetylation; PA; pattern of acetylation; CBM; carbohydrate-binding module; CBD; chitin-binding domain; PDD; polysaccharide deacetylase domain; Chitin deacetylase; Chitin binding domains;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Unraveling the mode of antifungal action of Bacillus subtilis and Bacillus amyloliquefaciens as potential biocontrol agents against aflatoxigenic Aspergillus parasiticus

Keywords: حالت عمل; Aspergillus parasiticus; Bacillus species; Antifungal activity; Biological control; Mode of action; Aflatoxins;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

A strategy for systemic toxicity assessment based on non-animal approaches: The Cosmetics Europe Long Range Science Strategy programme

Keywords: حالت عمل; ADME; absorption, distribution, metabolism, elimination; AOP; adverse outcome pathway; EFSA; European Food and Safety Agency; EURL ECVAM; European Union Reference Laboratory for Alternatives to Animal Testing; FDA; US Food and Drug Administration; IATA; I

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis and antibacterial activity of new peptides from Alfalfa RuBisCO protein hydrolysates and mode of action via a membrane damage mechanism against Listeria innocua

Keywords: حالت عمل; RuBisCO; Antibacterial peptides; Mode of action; Membrane permeability; Listeria innocua;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of bisphenol A on metabolism and evidences of a mode of action mediated through endocrine disruption

Keywords: حالت عمل; Bisphenol A; BPA; Endocrine disruption; Obesity; Type 2 diabetes; Insulin; BAT; brown adipose tissue; BMI; body mass index; bw; body weight; DES; diethylstilbestrol; DM; Diabete mellitus; ED; endocrine disruptor; eGFR; estimated glomerular filtration; ERR

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Evidence-based adverse outcome pathway approach for the identification of BPA as en endocrine disruptor in relation to its effect on the estrous cycle

Keywords: حالت عمل; Bisphenol A; Endocrine disruption; Female reproduction; Estrogen; ↑; increase; ↓; decrease; 2G; 2-generation study; 3G; 3-generation study; ANSES; Agence Nationale de Sécurité Sanitaire de l'alimentation, de l'environnement et du travail, (French Ag

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Nanoencapsulation: An efficient technology to boost the antimicrobial potential of plant essential oils in food system

Keywords: حالت عمل; Antimicrobials; Essential oils; Food preservatives; Mode of action; Nanotechnology;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

mGlu4 allosteric modulation for treating Parkinson's disease

Keywords: حالت عمل; Parkinson's disease; Dyskinesia; Glutamate; Dopamine; mGlu4; 6-OHDA; 6-hydroxydopamine; ADX88178; 4-methyl-N-[5-methyl-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-yl]pyrimidin-2-amine; AIM; abnormal involuntary movements; CODA-RET; complemented donor acceptor reson

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Role of Bacillus thuringiensis Cry1A toxins domains in the binding to the ABCC2 receptor from Spodoptera exigua

Keywords: حالت عمل; Mode of action; Cry receptor; Sf21 cells; HEK293T cells; Heterologous expression;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Ovicidal and larvicidal activity and possible mode of action of phenylpropanoids and ketone identified in Syzygium aromaticum bud against Bradysia procera

Keywords: حالت عمل; Syzygium aromaticum; Bradysia procera; Botanical insecticide; Botanical ovicide; Panax ginseng; Mode of action;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

AOP-DB: A database resource for the exploration of Adverse Outcome Pathways through integrated association networks

Keywords: حالت عمل; Adverse Outcome Pathways (AOPs); Risk assessment; Data mining; Database; Data integration; Association networks; ACHE; acetylcholinesterase; ACh; acetylcholine; AO; Adverse Outcome; AOP; Adverse Outcome Pathway; AOP-DB; Adverse Outcome Pathway Data Base;

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

Impairment of learning and memory performances induced by BPA: Evidences from the literature of a MoA mediated through an ED

Keywords: حالت عمل; Bisphenol A; Endocrine disruption; Learning and memory; Nervous system; 5α-R; 5 α-reductase; AChE; acetylcholinesterase; Akt; protein kinase B; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ANSES; Agence Nationale de Sécurité Sanitaire

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Transcriptional profiling of male CD-1 mouse lungs and Harderian glands supports the involvement of calcium signaling in acrylamide-induced tumors

Keywords: حالت عمل; Human health risk assessment; Mode of action; Lung; Harderian gland; Gene expression; Calcium signaling; Dose-response;

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2018 سفارش ترجمه

“The dose makes the poison”: Key implications for mode of action (mechanistic) research in a 21st century toxicology paradigm

Keywords: حالت عمل; Kinetically-derived Maximum Dose (KMD); Maximum Tolerated Dose (MTD); Linear-No-Threshold (LNT); ADME; Saturated metabolism; Mode of action;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Mode of action and human relevance of THF-induced mouse liver tumors

Keywords: حالت عمل; Tetrahydrofuran (THF); Constitutive androstane receptor (CAR); Mode of action; Liver tumors; Human relevance; Car/Pxr knockout mouse;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

AOPs in hazard characterization for human health

Keywords: حالت عمل; Mode of action; Adverse outcome pathways; Key event; Key event relationship; Weight of evidence; Quantitation; AO; adverse outcome; AOP; adverse outcome pathway; AOP-KB; adverse outcome pathway knowledge base; B/H; Bradford-Hill; EAGMST; OECD Extended Adv

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Potential use of cuminic acid as a botanical fungicide against Valsa mali

Keywords: حالت عمل; Apple valsa canker; Botanical fungicide; Cuminic acid; Disease management; Mode of action;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Discriminating modes of toxic action in mice using toxicity in BALB/c mouse fibroblast (3T3) cells

Keywords: حالت عمل; 3T3 cells; Mice; Mode of action; Toxic ratio; Threshold; Absorption kinetics;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Toxicity of oil sands acid-extractable organic fractions to freshwater fish: Pimephales promelas (fathead minnow) and Oryzias latipes (Japanese medaka)

Keywords: حالت عمل; Oil sands; Acid-extractable organics (AEO); Naphthenic acids (NA); Fractional distillation; Toxicity identification evaluation (TIE); Mode of action (MOA); Narcosis; AEO; Acid-extractable organics; MOA; Mode of action; NA; Naphthenic acids; OSPW; Oil sand

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Immune responses in the aquatic gastropod Lymnaea stagnalis under short-term exposure to pharmaceuticals of concern for immune systems: Diclofenac, cyclophosphamide and cyclosporine A

Keywords: حالت عمل; CAS number; chemical abstract service registry number; CP; cyclophosphamide; CSA; cyclosporine A; DC; diclofenac; DMSO; dimethyl sulfoxide; LMEM; linear mixed-effect model; MoA; mode of action; ROS; reactive oxygen species; SM; supplementary material; Gas

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Plasma membrane depolarization precedes photosynthesis damage and long-term leaf bleaching in (E)-chalcone-treated Arabidopsis shoots

Keywords: حالت عمل; Phenolic compound; Phytotoxicity; Mode of action; Thylakoid degradation; Bleaching;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Toxicity of Quaternary Ammonium Compounds (QACs) as single compounds and mixtures to aquatic non-target microorganisms: Experimental data and predictive models

Keywords: حالت عمل; ATMAC-16; hexadecyl trimethyl ammonium chloride; BAC-12; benzyl dimethyl dodecyl ammonium chloride; CA; Concentration Addition; C10TAB; decyl trimethyl ammonium bromide; C14TAB; tetradecyl trimethyl ammonium bromide; DADMAC-10; didecyl dimethyl ammonium c

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Update: Mode of action (MOA) for liver tumors induced by oral exposure to 1,4-dioxane

Keywords: حالت عمل; Dioxane; Regenerative hyperplasia; Liver toxicity; Mode of action; Risk assessment;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Auxin-like effects of the natural coumarin scopoletin on Arabidopsis cell structure and morphology

Keywords: حالت عمل; Coumarin; TIR1; Mode of action; Phytotoxicity; Secondary metabolite; Auxinic bioherbicide;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Next Generation Sequencing to characterise the breaking of bud dormancy using a natural biostimulant in kiwifruit (Actinidia deliciosa)

Keywords: حالت عمل; Bud break; Biostimulants; Dormancy; Kiwifruit; Mode of action; Next generation sequencing;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Integration of the TGx-28.65 genomic biomarker with the flow cytometry micronucleus test to assess the genotoxicity of disperse orange and 1,2,4-benzenetriol in human TK6 cells

Keywords: حالت عمل; BaP; benzo[a]pyrene; BT; 1,2,4-benzenetriol; 2DC; 2-dimensional hierarchical clustering; DO; disperse orange; HHRA; Human Health Risk Assessment; HESI; Health and Environmental Sciences Institute; MOA; Mode of Action; MN; micronucleus; NSC; Nearest Shrunk

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Integration of novel approaches demonstrates simultaneous metabolic inactivation and CAR-mediated hepatocarcinogenesis of a nitrification inhibitor

Keywords: حالت عمل; CAR; Mode of action; Pesticide; Metabolic inhibition/suicide inhibition; Human relevance framework;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Transcriptional profiling of male F344 rats suggests the involvement of calcium signaling in the mode of action of acrylamide-induced thyroid cancer

Keywords: حالت عمل; Human health risk assessment; Mode of action; Thyroid; Gene expression; Calcium signaling; Cytoskeleton;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Recent advances in discovery and development of natural products as source for anti-Parkinson's disease lead compounds

Keywords: حالت عمل; Parkinson's disease; Natural products; Mode of action; Signalling pathway;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

The increased toxicity of UV-degraded nitroguanidine and IMX-101 to zebrafish larvae: Evidence implicating oxidative stress

Keywords: حالت عمل; 95% C.I.; 95% confidence interval; BDL; below detection limits; cRNA; complementary RNA; DAVID; database for annotation, visualization and integrated discovery; DNAN; 2,4-dinitroanisole; GSEA; gene set enrichment analysis; IM; insensitive munition; KEGG;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Quantification of fungal growth and destruxin A during infection of Galleria mellonella larvae by Metarhizium brunneum

Keywords: حالت عمل; Real-time PCR; HPLC-MS; BIPESCO5; EAMa 01/58-Su; Mode of action; Risk assessment;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Relationship between acute and chronic toxicity for prevalent organic pollutants in Vibrio fischeri based upon chemical mode of action

Keywords: حالت عمل; Vibrio fischeri; Acute toxicity; Chronic toxicity; Mode of action;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

IARC use of oxidative stress as key mode of action characteristic for facilitating cancer classification: Glyphosate case example illustrating a lack of robustness in interpretative implementation

Keywords: حالت عمل; Glyphosate; IARC; Oxidative stress; Mechanism of action; Mode of action; Cancer classification;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه