Tissue remodeling in the acute otitis media mouse model
Keywords: مدل موش; Otitis media; Mouse model; Tissue remodeling; Cytokines
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Loss of striatal dopaminergic terminals during the early stage in response to MPTP injection in C57BL/6 mice
Keywords: مدل موش; Striatal dopaminergic terminal; MPTP; Immunoisolation; Dopamine transporter; Mouse model;
Overexpression of Shadoo protein in transgenic mice does not impact the pathogenesis of scrapie
Keywords: مدل موش; Overepression; Shadoo; Mouse model; Incubation times; Scrapie pathogenesis
Systemic cytokine response in moribund mice of streptococcal toxic shock syndrome model
Keywords: مدل موش; Streptococcus pyogenes; Streptococcal toxic shock syndrome; Cytokine; Mouse model;
A single intramuscular injection of neuraminidase inhibitor peramivir demonstrates antiviral activity against novel pandemic A/California/04/2009 (H1N1) influenza virus infection in mice
Keywords: مدل موش; Peramivir; Influenza; Mouse model; Intramuscular; Pandemic
Non-invasive system for applying airway obstructions to model obstructive sleep apnea in mice
Keywords: مدل موش; Animal model; Upper airway Obstruction; Mouse model; Non-invasive system; Model sleep apnea; Respiratory disease;
The impact of the learning curve on adhesion formation in a laparoscopic mouse model
Keywords: مدل موش; Learning curve; laparoscopy; adhesions; mouse model; training; surgery
Host specific differences alter the requirement for certain Salmonella genes during swine colonization
Keywords: مدل موش; Salmonella pathogenesis; Swine host; Mouse model; Systemic disease; Colonization; Iron transport; Genetic mechanisms;
Dynamic alterations of gene expression of nicotinic acetylcholine receptor α7, α4 and β2 subunits in an acute MPTP-lesioned mouse model
Keywords: مدل موش; MPTP; Mouse model; Parkinson's disease; Nicotinic acetylcholine receptors; mRNA
Downregulation of Caveolin-1 in a Murine Model of Acute Allergic Airway Disease
Keywords: مدل موش; acute allergic airway disease; airway remodeling; caveolin; collagen; mouse model
Synthesized pyridine compound derivatives decreased TNF alpha and adhesion molecules and ameliorated HSV-induced inflammation in a mouse model
Keywords: مدل موش; Pyridine compound derivative; Behcet's disease; Herpes simplex virus; TNF alpha; Oral administration; Anti-inflammation; Mouse model
Isotopic reinforcement of essential polyunsaturated fatty acids diminishes nigrostriatal degeneration in a mouse model of Parkinson's disease
Keywords: مدل موش; PD; Parkinson's disease; LA; linoleic acid; ALA; linolenic acid; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; PUFA; polyunsaturated fatty acid; D-PUFA; deuterated-PUFA; H-PUFA; hydrogenated PUFA; TH; tyrosine hydroxylase; HNE; 4-hydroxynonenal; HHE
Wound Healing Characteristics of ICAM-1 Null Mice Devoid of All Isoforms of ICAM-1
Keywords: مدل موش; ICAM-1; wound healing; LFA-1; sICAM-1; mouse model; tensiometry; leukocyte adhesion
Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status
Keywords: مدل موش; PPARγ; Fear conditioning; Hippocampus-dependent learning and memory; Mouse model; Alzheimer's disease; Glucose tolerance test; Insulin
Maternal background strain influences fetal–maternal trafficking more than maternal immune competence in mice
Keywords: مدل موش; Fetal cell trafficking; Mouse model; Background strain
Selection of rhinovirus 1A variants adapted for growth in mouse lung epithelial cells
Keywords: مدل موش; Picornavirus; Rhinovirus; Pathogenesis; Host range; Mouse model
Hsp90b1 knockout targeted to male germline: a mouse model for globozoospermia
Keywords: مدل موش; Gp96; Grp94; endoplasmic reticulum; spermiogenesis; male infertility; mouse model; Vasa-Cre;
Extranuclear signaling of mutated thyroid hormone receptors in promoting metastatic spread in thyroid carcinogenesis
Keywords: مدل موش; Thyroid hormone receptors; Thyroid hormone receptor mutants; Mouse model; Thyroid cancer; Carcinogenesis; Extranuclear signaling
Engineered human tumor xenografts with functional human vascular networks
Keywords: مدل موش; Tumor; Angiogenesis; Engineered vessels; Mouse model; Molecular imaging;
The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization
Keywords: مدل موش; Complement activation; Alternative pathway; Age-related macular degeneration; Choroidal neovascularization; VEGF; PEDF; Mouse model;
A neonatal mouse model of intermittent hypoxia associated with features of apnea in premature infants
Keywords: مدل موش; Mouse model; Intermittent hypoxia; Infantile apnea; Apnea of prematurity; White matter;
Autophagy failure in Alzheimer's disease-locating the primary defect
Keywords: مدل موش; Alzheimer's disease; Autophagy; Lysosome; Autolysosome; Dystrophic neurite; Proteolysis; Presenilin 1; Mouse model; Lysosomal storage disorders;
Antimalarial activity of imidazo[2,1-a]isoindol-5-ol derivatives and related compounds
Keywords: مدل موش; Synthesis; Imidazoisoindoles; In vitro assays; Plasmodium falciparum; Structure-activity relationship; In vivo assays; Mouse model; Plasmodium berghei;
Predictive validity of a non-induced mouse model of compulsive-like behavior
Keywords: مدل موش; Obsessive–compulsive disorder; Nesting; Mouse model; Fluoxetine; Clomipramine; Chronic oral administration
Reassessment of motor-behavioural test analyses enables the detection of early disease-onset in a transgenic mouse model of amyotrophic lateral sclerosis
Keywords: مدل موش; ALS, amyotrophic lateral sclerosis; ANOVA, analysis of variance; fALS, familial amyotrophic lateral sclerosis; hSOD1, human superoxide dismutase 1; sALS, sporadic amyotrophic lateral sclerosisAmyotrophic lateral sclerosis; hSOD1G93A; Mouse model; Grip str
IL-15 aggravates atherosclerotic lesion development in LDL receptor deficient mice
Keywords: مدل موش; Interleukin-15; Vaccination; Atherosclerosis; Inflammation; Mouse model;
Noninvasive Assessment of Atherosclerosis in Apolipoprotein-E Knockout Mice by Ultrasound Biomicroscopy
Keywords: مدل موش; Ultrasound; Mouse model; Atherosclerosis; Ultrasound biomicroscopy; Plasma lipids;
The effect of proatherogenic microbes on macrophage cholesterol homeostasis in apoE-deficient mice
Keywords: مدل موش; Periodontitis; Inflammation; Infection; Mouse model; Atherosclerosis
Reduced activity of the epithelial sodium channel in malaria-induced pulmonary oedema in mice
Keywords: مدل موش; Malaria; Lung; Pulmonary oedema; ENaC; Sodium transport; Mouse model
Effects of Age, Diet, and Type 2 Diabetes on the Development and FDG Uptake of Atherosclerotic Plaques
Keywords: مدل موش; atherosclerosis; diabetes; 18F-fluorodeoxyglucose; mouse model; positron emission tomographyApoB100/100, mouse expressing only apolipoprotein B100; ARG, autoradiography; CT, computed tomography; 18F-FDG, 18F-fluorodeoxyglucose; %IA/g, percentage of inject
A single dose of c9,t11 or t10,c12 conjugated linoleic acid isomers perturbs vitamin A metabolism in mice
Keywords: مدل موش; CLA, conjugated linoleic acid; RBP, retinol binding protein; HPLC, high-performance liquid chromatography; WT, wild-type; TAG, triglycerideVitamin A; Retinoid metabolism; Conjugated linoleic acid; Dietary fats; Mouse model
Coincident parasite and CD8 T cell sequestration is required for development of experimental cerebral malaria
Keywords: مدل موش; Cerebral malaria; Anti-malarial drug; Mouse model; CD8+ T cells; Plasmodium berghei;
Ginkgolide A-Gold Nanoparticles Inhibit Vascular Smooth Muscle Proliferation and Migration In Vitro and Reduce Neointimal Hyperplasia in a Mouse Model 1
Keywords: مدل موش; ginkgolide A; gold nanoparticles; smooth muscle cell; cell proliferation; cell migration; neointimal hyperplasia; mouse model
Genetic modifications of mouse proopiomelanocortin peptide processing
Keywords: مدل موش; Adrenal; Obesity; Mouse model; ACTH; α-MSH; Mutant;
Research reportA detailed analysis of the early context extinction deficits seen in APPswe/PS1dE9 female mice and their relevance to preclinical Alzheimer's disease
Keywords: مدل موش; Alzheimer's disease; Mouse model; Associative learning; Context extinction; Early Alzheimer's-like cognitive changes;
Experimental infection of Swiss Webster mice with four rat bartonella strains: Host specificity, bacteremia kinetics, dose dependent response, and histopathology
Keywords: مدل موش; Bartonella; Rattus; Rat; Mouse model; Bartonella coopersplainensis; Host specificity; Bacteremia; Dose response; Histopathology
Research ArticleLack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice
Keywords: مدل موش; Inflammation; Cytokines; IL-1; Fatty liver; Steatohepatitis; Lipid metabolism; Mouse model; NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; IL-1; interleukin-1; TNF; tumor necrosis factor; IL-1Ra; IL-1 receptor antagonist; I
Antiviral activity of the MEK-inhibitor U0126 against pandemic H1N1v and highly pathogenic avian influenza virus in vitro and in vivo
Keywords: مدل موش; Influenza virus; MEK-inhibitor; U0126; Mouse model
In vivo monitoring of recovery from neurodegeneration in conditional transgenic SCA1 mice
Keywords: مدل موش; SCA1; Mouse model; MRS; Cerebellum; Neurodegeneration;
Bone mineralization proceeds through intracellular calcium phosphate loaded vesicles: A cryo-electron microscopy study
Keywords: مدل موش; Biomineralization; Mouse model; Osteoblast; Calvaria; Carbonated hydroxyapatite; Transient precursor;
Effect of general anesthetics on IOP in elevated IOP mouse model
Keywords: مدل موش; IOP; mouse model; general anesthesia; awake IOP; behavioral training; glaucoma
The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain
Keywords: مدل موش; Brain-gut axis; Social stress; Social status; Mouse model; Corticosterone; Pro-inflammatory cytokines; Brain-gut axis disorders
Accelerated and Progressive and Lethal Liver Fibrosis in Mice That Lack Interleukin (IL)-10, IL-12p40, and IL-13Rα2
Keywords: مدل موش; Th2 Response; Mouse Model; Immune Regulation; T-Cell ResponseIFN, interferon; IL, interleukin; KO, knockout; Th, T-helper; TKO, triple knockout; WT, wild-type
Corticosterone selectively targets endo-cortical surfaces by an osteoblast-dependent mechanism
Keywords: مدل موش; Glucocorticoids; Cortical bone; Hydroxysteroid-dehydrogenase; Osteoblasts; Mouse model;
Intra-acinar Trypsinogen Activation Mediates Early Stages of Pancreatic Injury but Not Inflammation in Mice With Acute Pancreatitis
Keywords: مدل موش; PRSS1; Pancreas; Inflammatory Response; Regulation; Protease; Mouse Model; AP; acute pancreatitis; NF-κB; nuclear factor κB; T7; trypsinogen isoform 7; WT; wild-type;
Hepatic Overexpression of Abcb11 Promotes Hypercholesterolemia and Obesity in Mice
Keywords: مدل موش; Mouse Model; Micelle; Energy Expenditure; Bile Salt Export Pump; CYP7A1; cholesterol 7α-hydroxlyase; FGF; fibroblast growth factor; HMG-CoAR; HMG-CoA reductase; NPC1L1; Niemann-Pick C1 like 1; TTR; transthyretin; WT; wild-type;
Regulatory T Cells Suppress Development of Colitis, Blocking Differentiation of T-Helper 17 Into Alternative T-Helper 1 Cells
Keywords: مدل موش; Inflammatory Bowel Disease; Mouse Model; T-Cell Development; Immune ResponseCTLA, cytotoxic T lymphocyte−associated antigen; GFP, green fluorescent protein; Gr, Group; IBD, inflammatory bowel disease; IFN, interferon; LP, lamina propria; mRNA, messenger R
Ebola virus glycoprotein Fc fusion protein confers protection against lethal challenge in vaccinated mice
Keywords: مدل موش; Filoviridae; Glycoprotein; Fc fusion protein; Vaccine; Mouse model; Zaire Ebola virus; Neutralizing antibodies; T-cell immunity; Interferon-gamma
TGFBI expression reduces in vitro and in vivo metastatic potential of lung and breast tumor cells
Keywords: مدل موش; TGFBI; Metastasis; Extracellular matrix; Adhesion-mediated signaling; Mouse model
Loss of Function Studies in Mice and Genetic Association Link Receptor Protein Tyrosine Phosphatase α to Schizophrenia
Keywords: مدل موش; Mouse model; myelination; PTPRA; RPTPα; schizophrenia; tyrosine phosphatase