Rift Valley fever virus NSS gene expression correlates with a defect in nuclear mRNA export
Keywords: mRNA; Rift Valley fever virus; NSS; RNA export; PABP1;
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ZnO nanoparticles augment ALT, AST, ALP and LDH expressions in C2C12 cells
Keywords: C2C12 cells; Antioxidant; ZnO nanoparticles; Cytotoxicity; Enzymes; mRNA
Individual and combined inhibitory effects of methanol and toluene on acetyl-CoA synthetase expression level of acetoclastic methanogen, Methanosaeta concilii
Keywords: Acetyl-CoA synthetase; FISH; Methanol; Methanosaeta concilii; mRNA; Real-time PCR; Toluene
Myocardial ischemic preconditioning in a porcine model leads to rapid changes in cardiac extracellular vesicle messenger RNA content
Keywords: Extracellular vesicles; mRNA; Transcription; Ischemic preconditioning; Myocardium
Oxidized low-density lipoprotein accelerates the destabilization of extracellular-superoxide dismutase mRNA during foam cell formation
Keywords: Extracellular-superoxide dismutase; Oxidized low-density lipoprotein; 3′-Untranslated region; mRNA; Destabilization
ANXA1Ac2-26 peptide reduces ID1 expression in cervical carcinoma cultures
Keywords: [LaCit2]3; lanthanum citrate complex; μg; microgram; ACTB; beta-actin; ANX; annexin; ANXA1; annexin A1; BMP4; bone morphogenetic protein 4; BMPR1B; bone morphogenetic protein receptor, type IB; cDNA; complementary DNA; CO2; carbon dioxide; DNA; deoxyribo
Downregulation of Umbilical Cord Blood Levels of miR-374a in Neonatal Hypoxic Ischemic Encephalopathy
Keywords: EEG; Electroencephalogram; HIE; Hypoxic ischemic encephalopathy; miRNA; MicroRNA; mRNA; Messenger RNA; qRT-PCR; Quantitative real-time polymerase chain reaction;
Sex differences in GABAergic gene expression occur in the anterior cingulate cortex in schizophrenia
Keywords: Antipsychotic; γ-Aminobutyric acid; Receptor; mRNA; Gender; Postmortem brain;
Soft computing model for optimized siRNA design by identifying off target possibilities using artificial neural network model
Keywords: siRNA; small interfering RNA; miRNA; microRNA; mRNA; messenger RNA; RNAi; RNA interference; ROC; receiver operating characteristics; AUC; Area Under Curve; dsRNA; double stranded RNA; ANN; artificial neural network; OpsiD; Optimized siRNA Designer; MCC; M
Nuclear EGFR renders cells radio-resistant by binding mRNA species and triggering a metabolic switch to increase lactate production
Keywords: nEGFR; mRNA; Hif1α; PDH; Warburg effect;
Dipyridamole-induced C-type natriuretic peptide mRNA overexpression in a minipig model of pacing-induced left ventricular dysfunction
Keywords: C-type natriuretic peptide; Dipyridamole; mRNA; Left ventricular dysfunction; RIA;
The effect of B-cell depletion in the Theiler's model of multiple sclerosis
Keywords: BCD; B cell depletion; MS; multiple sclerosis; TMEV; Theiler's murine encephalomyelitis virus; TMEV-IDD; Theiler's murine encephalomyelitis virus-induced demyelinating disease; CD; cluster of differentiation; RT-PCR; reverse transcription polymerase chain
N1-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice
Keywords: N1-methylpseudouridine (PubChem CID: 99543); pseudouridine (PubChem CID: 15047); 5-methylcytidine (PubChem CID: 92918); mRNA; Modified RNA; Nucleobase modifications; Antiviral innate immunity; Toll-like receptor; Gene therapy;
Dimerization model of the C-terminal RNA Recognition Motif of HuR
Keywords: AREs; Adenylate and uridylate Rich Elements; BD; Brownian Dynamics; COM; center of mass; ELAV; Embryonic Lethal and Abnormal Vision; Grb7; Growth factor receptor-bound protein 7; HuR; Human antigen R; mRNA; messenger RNA; MD; Molecular Dynamics; NMR; nucl
CREB expression mediates amyloid β-induced basal BDNF downregulation
Keywords: Alzheimer's disease; Amyloid-β; Brain-derived neurotrophic factor; cAMP response element binding protein; Human neuroblastoma SH-SY5Y; mRNA;
RNA epigenetics
Keywords: lncRNA; long noncoding RNA; m1A; N1-methyl-A; m1G; N1-methyl-G; m5C; 5-methyl cytosine; m6A; N6-methyl adenosine; METTL14; Methyltransferaselike 14; mRNA; Messenger RNA; Nm; 2â²-O-methyl nucleotides; Ψ; pseudouridine; RT; reverse transcriptase; tRNA; tr
Analysis of differentially expressed lncRNAs in differentiation of bone marrow stem cells into neural cells
Keywords: Differentiation; Bone marrow stem cells; Neural cells; lncRNA; mRNA; Microarray analysis
Comparing triage algorithms using HPV DNA genotyping, HPV E7 mRNA detection and cytology in high-risk HPV DNA-positive women
Keywords: AIS; adenocarcinoma in situ; BMD; borderline or mild dyskariosis; CI; confidence interval; CIN; cervical intraepithelial neoplasia; DNA; deoxyribonucleic acid; EIA; enzyme immunoassay; HPV; human papillomavirus; hrHPV; high risk human papillomavirus; LLET
Research ArticleDysregulated miR-124 and miR-200 expression contribute to cholangiocyte proliferation in the cholestatic liver by targeting IL-6/STAT3 signalling
Keywords: miRNA; microRNA; 3â² UTR; 3â² untranslated region; mRNA; messenger RNA; IL-6; interleukin-6; STAT3; signal transducer and activator of transcription 3; PCR; polymerase chain reaction; PCNA; proliferating cell nuclear antigen; GAPDH; glyceraldehyde 3-pho
MicroRNA-146a reduces IL-1 dependent inflammatory responses in the intervertebral disc
Keywords: ADAMTS; a disintergrin and metalloproteinase with thrombospondin motifs; ANOVA; analysis of variance; COX-2; cyclooxygenase-2; Ct; threshold cycle; DAB; 3, 3â²-diaminobenzidine; DMEM; Dulbecco's modified eagle medium; IHC; immunohistochemical; EGFR; epid
Distribution of EP4 receptor in different Atlantic salmon (Salmo salar L.) tissues
Keywords: Atlantic salmon EP4; Tissue distribution; mRNA; Immunohistochemistry; Immune organs;
Research paperLinear mRNA amplification approach for RNAseq from limited amount of RNA
Keywords: aRNA; amplified RNA; bp; base pairs; cDNA; complementary DNA; dN15; random oligonucleotide; DNA; deoxyribonucleic acid; dscDNA; double stranded cDNA; ERBB2; epithelial growth factor receptor II; LCM; laser capture microdissection; min; minute; mRNA; Messe
Development of an in situ hybridization assay for the detection of ostreid herpesvirus type 1 mRNAs in the Pacific oyster, Crassostrea gigas
Keywords: Ostreid herpesvirus type 1; Crassostrea gigas; Pacific oyster; Viral infection; In situ hybridization; mRNA
Roles of miRNAs in microcystin-LR-induced Sertoli cell toxicity
Keywords: Microcystin-LR; microRNA; mRNA; Sertoli cell; Bioinformatics; Toxicity;
Early decline in functional ovarian reserve in young women with low (CGGn < 26) FMR1 gene alleles
Keywords: AMH; anti-Müllerian hormone; ART; assisted reproductive technology; BMI; body mass index; FMR1; fragile X mental retardation 1; FOR; functional ovarian reserve; FSH; follicle stimulating hormone; FXPOI; fragile X primary ovarian insufficiency; GEE; gener
Investigation of Geotrichum candidum gene expression during the ripening of Reblochon-type cheese by reverse transcription-quantitative PCR
Keywords: Cheese; Reblochon; Geotrichum candidum; mRNA; Gene expression; Reverse transcription-quantitative PCR
Exposure to toxic Alexandrium minutum activates the detoxifying and antioxidant systems in gills of the oyster Crassostrea gigas
Keywords: Crassostrea gigas; Alexandrium minutum; Paralytic shellfish toxins; Antioxidant enzymes; Detoxification enzymes; mRNA
Anti-inflammatory effect of desoxo-narchinol-A isolated from Nardostachys jatamansi against lipopolysaccharide
Keywords: COX-2; cyclooxygenase-2; DN; desoxo-narchinol-A; ELISA; enzyme-linked immunosorbent assay; ERK; extracellular signal-regulated kinase; EtOAc; ethyl acetate; FBS; fetal bovine serum; H&E; hematoxylin and eosin; HPRT; hypoxanthine guanine phosphoribosyl-tra
The role of chromatin repressive marks in cognition and disease: A focus on the repressive complex GLP/G9a
Keywords: AAV-Cre; adeno-associated virus with Cre recombinase; AMPA; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BDNF; brain-derived neurotrophic factor; BIX-01924; G9a inhibitor; CA1; cornu ammonis 1; DNA; deoxyribonucleic acid; Drd1; dopamine recep
Stress-induced modulation of NF-κB activation, inflammation-associated gene expression, and cytokine levels in blood of healthy men
Keywords: Stress; TSST; mRNA; Cytokines; Interleukin-1β; Interleukin-6; Interleukin-10; NF-κB; IκBα;
eQTL networks unveil enriched mRNA master integrators downstream of complex disease-associated SNPs
Keywords: Translational bioinformatics; Centrality; Complex diseases; eQTL; Single Nucleotide Polymorphism (SNP); Master integrator; Computational genomics; Genomics; Transcriptome; mRNA; Network biology; Big data; Computational biology; Computational medicine; Com
In silico prediction and validation of potential gene targets for pospiviroid-derived small RNAs during tomato infection
Keywords: Aa; amino acid; ABSVd; avocado sunblotch viroid; AFCVd; apple fruit crinkle viroid; AGO; argonaute; AGVd; Australian grapevine viroid; ASSVd; apple scar skin viroid; CBVd; Coleus blumei viroid; CBCVd; citrus bark cracking viroid; CBLVd; citrus bent leaf v
Soil N cycling processes in a pasture after the cessation of grazing and CO2 enrichment
Keywords: Heterotrophic nitrification; Microbial functional groups; mRNA; Nitrous oxide;
Modulating prime molecular expressions and in vitro wound healing rate in keratinocyte (HaCaT) population under characteristic honey dilutions
Keywords: BSA; Bovine Serum Albumin; DMEM-F12; Delbecco׳s Modified Eagle Media-Nutrient Mixture F12 Ham; DPPH; 2, 2-Diphenyl-1-picryylhydrazyl; EMT; Epithelio-Mesenchymal Transition; FBS; Fetal bovine serum; GAE; Gallic Acid Equivalence; GAPDH; Glyceraldehyde 3-ph
mRNA metabolism and neuronal disease
Keywords: mRNA; Genetic disease; Splicing; Post-transcriptional regulation of gene expression; mRNA turnover;
Hypermethylation of potential tumor suppressor miR-34b/c is correlated with late clinical stage in patients with soft tissue sarcomas
Keywords: A; adenine; ASPS; alveolar soft part sarcoma; ASS1; argininosuccinate synthetase 1; BMP2; bone morphogenetic protein 2; C; cytosine; Da; Dalton; DFSP; dermatofibrosarcoma protuberan; DNA; deoxyribonucleic acid; EDTA; ethylenediaminetetraacetic acid; ES/pP
Effects of atrazine and chlorpyrifos on DNA methylation in the brain and gonad of the common carp
Keywords: DNA methylation; Pesticides; mRNA; Western blot; Fish; Principal component analysis;
CX3CR1 is dysregulated in blood and brain from schizophrenia patients
Keywords: CX3CR1; Schizophrenia; mRNA; Inflammation; Transcriptomics; Meta-analysis;
CAP+ selection: A combined chemical-enzymatic strategy for efficient eukaryotic messenger RNA enrichment via the 5â² cap
Keywords: mRNA; 5â² Cap; Biotinylation; Purification;
MiR-10a and miR-181c regulate collagen type I generation in hypertrophic scars by targeting PAI-1 and uPA
Keywords: ECM; extracellular matrix; HS; hypertrophic scar; HF; hypertrophic scar-derived fibroblast; NF; normal skin-derived fibroblast; mRNA; messenger RNA; miRNA; microRNA; RT-PCR; reverse transcription polymerase chain reaction; UTR; untranslated region; uPA; u
ReviewmiR-122 - A key factor and therapeutic target in liver disease
Keywords: miRNA; microRNA; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; RNAi; RNA interference; Ago; Argonaute; RISC; RNA-induced silencing complex; mRNA; messenger RNA; 3â² UTR; 3â² untranslated region; 5â² UTR; 5â² untranslated region; DAA; direct-a
Molecular profiling and functional insights of rock bream (Oplegnathus fasciatus) thioredoxin reductase 3-like molecule: investigation of its transcriptional modulation in response to live pathogen stress
Keywords: Trx; thioredoxin; TrxR; thioredoxin reductase; PCR; polymerase chain reaction; qPCR; quantitative real time PCR; NADPH; nicotinamide adenine dinucleotide phosphate; ROS; reactive oxygen species; NADH; nicotinamide adenine dinucleotide; FAD; flavin adenine
Altered Expression of CDC42 Signaling Pathway Components in Cortical Layer 3 Pyramidal Cells in Schizophrenia
Keywords: Actin cytoskeleton; CDC42; Dendritic spine; mRNA; Prefrontal cortex; Schizophrenia
Paradoxically, iron overload does not potentiate doxorubicin-induced cardiotoxicity in vitro in cardiomyocytes and in vivo in mice
Keywords: ANP; atrial natriuretic peptide; AU; arbitrary unit; β-MHC; beta-myosin heavy chain; BNP; brain natriuretic peptide; cDNA; complementary deoxyribonucleic acid; DOX; doxorubicin; ECG; electrocardiogram; ESR; electron spin resonance; ET; ventricular ejecti
Interaction of VP8 with mRNAs of bovine herpesvirus-1
Keywords: BoHV1; VP8; bICP0; mRNA
Peptidic tools applied to redirect alternative splicing events
Keywords: ANP; atrial natriuretic peptide; ASBNP; alternatively spliced BNP; ASO; antisense oligonucleotides; BNP; B-type natriuretic peptide; CBD; calmodulin binding domain; CPP; cell penetrating peptides; DMD; Duchenne muscular dystrophy; ESE; exonic splicing enh
Genome-wide transcriptome analysis of mRNAs and microRNAs in Dorset and Small Tail Han sheep to explore the regulation of fecundity
Keywords: Sheep; High prolificacy; mRNA; miRNA; RNA-Seq;
COPD Exacerbations Are Associated With Proinflammatory Degradation of Hyaluronic Acid
Keywords: AECOPD; acute exacerbation of COPD; ECM; extracellular matrix; ELISA; enzyme-linked immunosorbent assay; GOLD; Global Initiative for Chronic Obstructive Lung Disease; HA; hyaluronic acid; HAS; hyaluronic acid synthase; HYAL; hyaluronidase; mRNA; messenger
Molecular cloning and sequence analysis of heat shock proteins 70 (HSP70) and 90 (HSP90) and their expression analysis when exposed to benzo(a)pyrene in the clam Ruditapes philippinarum
Keywords: cDNA; DNA complementary to RNA; HSP70; heat shock protein 70 gene; HSP90; heat shock protein 90 gene; XMEs; xenobiotic metabolizing enzymes; BaP; benzo(a)pyrene; PCR; polymerase chain reaction; RT-PCR; reverse transcriptase PCR; qRT-PCR; quantitative RT-P
Novel splice isoforms of dairy goat DBC1 and their diverse mRNA expression profiles
Keywords: DBC1; deleted in breast cancer 1; DBC1a; deleted in breast cancer 1a; SIRT1; sirtuin 1; ERα; estrogen receptors α; ERβ; estrogen receptors β; NAD+; nicotinamide adenine dinucleotide; RT-PCR; reverse transcript polymerase chain reaction; qRT-PCR; quant