دانلود مقالات ISI درباره Mtor + ترجمه فارسی

The roles of extracellular related-kinases 1 and 2 signaling in CNS myelination

Keywords: Erk; Akt; Fyn; BDNF; Oligodendrocyte; Myelin; Erk1/2; extracellular related-kinase 1 and 2; BDNF; brain-derived neurotrophic factor; NGF; nerve growth factor; NT-3; neurotrophin 3; CNS; central nervous system; PNS; peripheral nervous system; p75NTR; p75 n

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibitions of mTORC1 and 4EBP-1 are key events orchestrated by Rottlerin in SK-Mel-28 cell killing

Keywords: Rottlerin; AMPK; mTOR; 4EBP-1; Autophagy; Protein synthesis; RPMI; Roswell Park Memorial Institute (RPMI); Becl-1; beclin-1; AMPK; AMP-activated protein kinase; ACC; acetyl-CoA carboxylase; mTOR; mammalian target of rapamycin; raptor; regulatory-associate

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

MEK-ERK inhibition potentiates WAY-600-induced anti-cancer efficiency in preclinical hepatocellular carcinoma (HCC) models

Keywords: Hepatocellular carcinoma (HCC); mTOR; WAY-600; MEK-ERK; Combined treatment;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and anticancer activity of novel 4-morpholino-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine derivatives bearing chromone moiety

Keywords: Thiopyranopyrimidine; Chromone; Synthesis; Docking; mTOR; PI3Kα; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Lkb1 deletion upregulates Pax7 expression through activating Notch signaling pathway in myoblasts

Keywords: AMPK; AMP-activated protein kinase; BAT; brown adipose tissue; DAPT; N-[N-(3,5-difluorophenacetyl-l-alanyl)]-S-phenylglycine t-butyl ester; FBS; fetal bovine serum; H&E; hematoxylin and eosin; Lkb1; Liver kinase B1; mTOR; mammalian target of rapamycin; N1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Concomitant reduction of c-Myc expression and PI3K/AKT/mTOR signaling by quercetin induces a strong cytotoxic effect against Burkitt's lymphoma

Keywords: Q; quercetin; BL; Burkitt's lymphoma; BCR; B cell receptor; GC; Germinal Center; EBV; Epstein-Barr virus; PI3K; phosphatidylinositol-3-kinase; AKT; AKT or protein kinase B; mTOR; mammalian target of rapamycin; BEZ235; NVP-BEZ235; I-c-Myc; c-Myc inhibi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Probucol inhibits neural cell apoptosis via inhibition of mTOR signaling pathway after spinal cord injury

Keywords: AMPK; AMP-activated protein kinase; BBB; Basso, Beattie, and Bresnahan; BSA; bovine serum albumin; CNS; central nervous system; DMSO; dimethyl sulfoxide; mTOR; mammalian target of rapamycin; p70S6K; S6 kinase p70 subtype; PBS; phosphate-buffered saline; S

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Antidepressant drug action - From rapid changes on network function to network rewiring

Keywords: 5-HT; serotonin; AMPA; amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BDNF; brain-derived neurotrophic factor; DBS; deep brain stimulation; ECS; electroconvulsive shock; ECT; electroconvulsive therapy; GABA; gamma-aminobutyric acid; mTOR; mammalian t

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Activation of AMPK inhibits PDGF-induced pulmonary arterial smooth muscle cells proliferation and its potential mechanisms

Keywords: Pulmonary arterial smooth muscle cells; AMPK; mTOR; p27; Skp2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Sporadic versus Tuberous Sclerosis Complex-Associated Angiomyolipomas: Predictors for Long-Term Outcomes following Transcatheter Embolization

Keywords: AML; angiomyolipoma; mTOR; mammalian target of rapamycin; PD; progressive disease; RECIST; Response Evaluation Criteria In Solid Tumors; TSC; tuberous sclerosis complex;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Original ArticleSuppression of miR-19b enhanced the cytotoxic effects of mTOR inhibitors in human neuroblastoma cells

Keywords: AZD8055; miR-19b; mTOR; Neuroblastoma;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

A randomized phase II non-comparative study of PF-04691502 and gedatolisib (PF-05212384) in patients with recurrent endometrial cancer

Keywords: Endometrial cancer; Gedatolisib; mTOR; PI3K; Stathmin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

mTORC1 mediates peptidoglycan induced inflammatory cytokines expression and NF-κB activation in macrophages

Keywords: mTOR; Peptidoglycan; TLR1/TLR2; Inflammatory responsemTORC1, Mammalian target of rapamycin complex 1; TNF-α, tumor necrosis factor α; IL-6, interleukin-6; IL-10, interleukin-10; PGN, Peptidoglycan; TLR, Toll-like receptor; PAMP, pathogen-associated molecu

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

mTOR, metabolism, and the immune response in HPV-positive head and neck squamous cell cancer

Keywords: Head and neck oropharyngeal carcinoma; Human papillomavirus; Metabolism; mTOR; Rapamycin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Genistein-induced LKB1–AMPK activation inhibits senescence of VSMC through autophagy induction

Keywords: Genistein; LKB1; AMPK; mTOR; Autophagy; Senescence; Vascular smooth muscle cell (VSMC)

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

AKT signaling in ERBB2-amplified breast cancer

Keywords: PI3K; mTOR; Trastuzumab; Targeted therapy; Drug resistance; AKT3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Huaier aqueous extract sensitizes cells to rapamycin and cisplatin through activating mTOR signaling

Keywords: Huaier; Rapamycin; Cisplatin; mTOR; Cancer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Fingolimod ameliorates the development of experimental autoimmune encephalomyelitis by inhibiting Akt–mTOR axis in mice

Keywords: Multiple sclerosis; Experimental autoimmune encephalomyelitis; Fingolimod; mTOR; Treg cell; Th1 cell

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Comparison of the transcriptional responses of skeletal muscle and bone to a flooding dose of leucine in the gilthead sea bream (Sparus aurata)

Keywords: NGS; Muscle; Bone; Expression; Leucine; mTOR; Fast growth; Aquaculture; Skeletal deformities

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Ghrelin induces colon cancer cell proliferation through the GHS-R, Ras, PI3K, Akt, and mTOR signaling pathways

Keywords: Colon cancer; Ghrelin; Proliferation; Ras; PI3K/Akt; mTOR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Rosemary extract reduces Akt/mTOR/p70S6K activation and inhibits proliferation and survival of A549 human lung cancer cells

Keywords: Rosemary extract; Lung cancer; Proliferation; Survival; Akt; mTOR; p70S6K

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Rapamycin reduces motivated responding for cocaine and alters GluA1 expression in the ventral but not dorsal striatum

Keywords: Cocaine; Striatum; mTOR; Nucleus accumbens; Rapamycin; Progressive ratio

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Alterations of mTOR and PTEN protein expression in schistosomal squamous cell carcinoma and urothelial carcinoma

Keywords: MTOR; PTEN; Urothelial carcinoma; Squamous cell carcinoma

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Suppression of REDD1 in osteoarthritis cartilage, a novel mechanism for dysregulated mTOR signaling and defective autophagy

Keywords: REDD1; mTOR; Cartilage; Osteoarthritis; Autophagy;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Desmethylanhydroicaritin isolated from Sophora flavescens, shows antitumor activities in U87MG cells via inhibiting the proliferation, migration and invasion

Keywords: MAPK; mitogen activated protein kinase; PI3K; phosphoinositide 3-kinase; MMP; matrix metalloproteinase; WST-1; 2-(4-iodophenyl)-3(40nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium; DAPI; 4,6-diamidino2-phenylindole dihydrochloride hydrate; PBS; phosphat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportResveratrol exerts antidepressant properties in the chronic unpredictable mild stress model through the regulation of oxidative stress and mTOR pathway in the rat hippocampus and prefrontal cortex

Keywords: BDNF; brain-derived neurotrophic factor; CUMS; chronic unpredictable mild stress; FST; forced swimming test; GSH; glutathione; MDA; malondialdehyde; mTOR; mammalian target of rapamycin; PFC; prefrontal cortex; ROS; reactive oxygen species; SOD; superoxide

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportNa+, K+-ATPase dysfunction causes cerebrovascular endothelial cell degeneration in rat prefrontal cortex slice cultures

Keywords: CBF; cerebral blood flow; DMSO; dimethylsulfoxide; ER; endoplasmic reticulum; GSK3β; glycogen synthase kinase 3β; IP3 receptor; inositol triphosphate receptor; MAPK; mitogen-activated protein kinase; mTOR; mammalian target of rapamycin; NCX; Na+, Ca2+ e

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Dual role of LRRC8A-containing transporters on cisplatin resistance in human ovarian cancer cells

Keywords: A2780WT; drug-sensitive human ovarian cancer cells; A2780CisR; cisplatin resistant A2780 cells; ABC; ATP-binding cassette; Ano6; Anoctamin 6; Apaf-1; apoptotic protease activating factor 1; Atox1; Antioxidant 1 copper chaperone; AP; alkaline phosphatase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

mTOR inhibition attenuates glucose deprivation-induced death in photoreceptors via suppressing a mitochondria-dependent apoptotic pathway

Keywords: mTOR; Mitochondrial membrane potential; Rapamycin; Photoreceptor cells; Oxidative stress; DRP1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Valproic acid exposure sequentially activates Wnt and mTOR pathways in rats

Keywords: VPA; Wnt; mTOR; Autism spectrum disorder; Autophagy;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

tPA promotes cortical neuron survival via mTOR-dependent mechanisms

Keywords: DIV; days in vitro; JAK; Janus kinase; mTOR; mammalian target of rapamycin; p2; postnatal day 2; PDL; poly-d-lysine; p-S6; phospho-S6; p-STAT3; phosphorylated signal transducer and activator of transcription 3; tPA; tissue plasminogen activator; Tissue pl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Angiotensin-converting enzyme 2 ameliorates renal fibrosis by blocking the activation of mTOR/ERK signaling in apolipoprotein E-deficient mice

Keywords: Angiotensin-converting enzyme 2; mTOR; Renal fibrosis; Apolipoprotein E; Atherosclerosis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Gene expression profiling reveals the role of RIG1 like receptor signaling in p53 dependent apoptosis induced by PUVA in keratinocytes

Keywords: PUVA; 8-methoxypsoralen plus UVA; RIG-1; retinoic acid induced gene 1; MDA5; melanoma differentiation associated gene 5; MAVS; mitochondrial antiviral signaling protein; TBK; TANK-binding kinase 1; IKKε; inhibitor of kappaB kinase epsilon; IRF3; interfer

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of feed deprivation on the AMPK signaling pathway in skeletal muscle of broiler chickens

Keywords: AMPK; Broiler; Fasting; mTOR; Skeletal muscle

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Research PaperRAD001 (everolimus) attenuates experimental autoimmune neuritis by inhibiting the mTOR pathway, elevating Akt activity and polarizing M2 macrophages

Keywords: GBS; Guillain-Barre' syndrome; EAN; experimental autoimmune neuritis; mTOR; mammalian target of rapamycin; PNS; peripheral nervous system; PBS; phosphate-buffered saline; dpi; days post-immunization; EMG; electromyography; CMAP; compound muscle action pot

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Early onset epileptic encephalopathy or genetically determined encephalopathy with early onset epilepsy? Lessons learned from TSC

Keywords: Tuberous sclerosis; Epileptic encephalopathy; Genetics; mTOR; Vigabatrin;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Activation of AMPK α2 inhibits airway smooth muscle cells proliferation

Keywords: LY294002 (PubChem CID: 11957589); Rapamycin (PubChem CID: 5284616)AMPK; Airway smooth muscle cells; MTOR; Skp2; P27

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

The role of epsilon PKC in acute and chronic diseases: Possible pharmacological implications of its modulators

Keywords: PKC; protein kinase C; IPC; ischemic pre conditioning; RACK; receptor for activated C-kinase; DAG; diacylglycerol; beta COP; coatomer subunit beta; CHOK1; chinese hamster ovary K1; CVD; cardiovascular disease; mKATP; ATP-sensitive mitochondrial potassium

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Histone deacetylase inhibitors reduce WB-F344 oval cell viability and migration capability by suppressing AKT/mTOR signaling in vitro

Keywords: Oval cells; AKT/mTOR signaling pathway; Histone deacetylase inhibitor; Rapamycin; Cell proliferation; ApoptosisHDAC, Histone deacetylase; SAHA, suberoylanilidehydroxamic acid; TSA, trichostatin-A; HCC, hepatocellular carcinoma; AKT, Protein Kinase B; mTOR

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

DT-13, a saponin monomer of dwarf lilyturf tuber, induces autophagy and potentiates anti-cancer effect of nutrient deprivation

Keywords: DT-13 (PubChem CID: 101514160); Bafilomycin A1 (PubChem CID: 6436223); Chloroquine (PubChem CID: 2719)DT-13; Nutrient deprivation; Autophagy; Apoptosis; mTOR

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Nutrients and the microenvironment to feed a T cell army

Keywords: T cell metabolism; mTOR; Glut1; Glutamine; Epigenetics; Circadian rhythms;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration

Keywords: AMP-activated protein kinase AMPK; Lipogenesis; SGLT2; Prostate cancer; Lung cancer; Breast cancer; Colon cancer; mTOR; Cancer metabolism; Glucose uptake; 2-DG; 2-deoxy-d-glucose; ACC; acetyl-CoA carboxylase; AD-AMPKDN; adenoviral alpha-1 dominant negativ

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Rosmarinic acid stimulates liver regeneration through the mTOR pathway

Keywords: Liver regeneration; Rosmarinic acid; mTOR; Rosemary; Proliferation; Partial hepatectomy; RA; Rosmarinic acid; PH; Partial hepatectomy; PI3K; Phosphoinositide-3 kinase; mTOR; Mammalian target of rapamycin; S6K; S6 protein kinase 1; PCNA; Proliferating cell

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Research ArticleMethionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis

Keywords: GNMT; glycine N-methyltransferase; SAMe; S-adenosylmethionine; MTOR; the mammalian target of rapamycin; PP2A; protein phosphatase 2A; LD; lipid droplets; MAT; methionine adenosyltransferase; SAH; S-adenosylhomocysteine; DG; diglyceride; TG; triglycerides;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Pharmacotherapies for Retinal Detachment

Keywords: AIF; apoptosis-inducing factor; Faim2; Fas apoptotic inhibitory molecule 2; FDA; US Food and Drug Administration; MCP-1; monocyte chemoattractant protein-1; mTOR; mammalian target of rapamycin; PDGF; platelet-derived growth factor; PDGFRα; platelet-deri

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Depdc5 knockout rat: A novel model of mTORopathy

Keywords: DEPDC5; Familial focal epilepsy; Focal cortical dysplasia; mTOR; Rapamycin; Knockout;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportPTP4A3 is a target for inhibition of cell proliferatin, migration and invasion through Akt/mTOR signaling pathway in glioblastoma under the regulation of miR-137

Keywords: miR-137; PTP4A3; Akt; mTOR; Glioblastoma multiforme;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Everolimus improves memory and learning while worsening depressive- and anxiety-like behavior in an animal model of depression

Keywords: Depression; Anxiety; Cognitive function; mTOR; Neurogenesis; Mice;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Rapamycin Decreases the Osteogenic Response in Aortic Valve Interstitial Cells Through the Stat3 Pathway

Keywords: ALP; alkaline phosphatase; AVICs; aortic valve interstitial cells; BMP-2; bone morphogenetic protein 2; CAVD; calcific aortic valve disease; LPS; lipopolysaccharide; mTOR; mammalian target of rapamycin; RUNX2; runt-related transcription factor 2; Stat3; s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Alterations in BRAF gene, and enhanced mTOR and MAPK signaling in dysembryoplastic neuroepithelial tumors (DNTs)

Keywords: Dysembryoplastic neuroepithelial tumor; Epilepsy; BRAF; mTOR; MAPK;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه