دانلود مقالات ISI درباره Mtor + ترجمه فارسی

Improvement of mTORC1-driven overproduction of apoB-containing triacylglyceride-rich lipoproteins by short-chain fatty acids, 4-phenylbutyric acid and (R)-α-lipoic acid, in human hepatocellular carcinoma cells

Keywords: ACC; acetyl-CoA carboxylase; Akt; protein kinase B; AMPK; AMP-activated protein kinase; apoB; apolipoprotein B; apoE; apolipoprotein E; CPT1α; carnitine palmitoyltransferase 1α; DGAT1; diacylglycerol O-acyltransferase 1; DGAT2; diacylglycerol O-acyltran

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Review ArticleIntracellular signaling pathway regulation of myelination and remyelination in the CNS

Keywords: Wnt/β-catenin; PI3K/AKT; mTOR; ERK MAPK; Oligodendrocyte development; Myelination; Remyelination; Intracellular signaling;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Alterations in BRAF gene, and enhanced mTOR and MAPK signaling in dysembryoplastic neuroepithelial tumors (DNTs)

Keywords: Dysembryoplastic neuroepithelial tumor; Epilepsy; BRAF; mTOR; MAPK;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Chloroquine inhibits lytic replication of Kaposi's sarcoma-associated herpesvirus by disrupting mTOR and p38-MAPK activation

Keywords: Kaposi's sarcoma-associated herpesvirus; Lytic replication; Chloroquine; mTOR; p38-MAPK;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Cardiac ubiquitin ligases: Their role in cardiac metabolism, autophagy, cardioprotection and therapeutic potential

Keywords: ATG; autophagy-related gene; AMPK; AMP activated protein kinase; BECN1; beclin1; b-TrCP; beta-transducin repeat-containing protein; Cbl; Casitas B-lineage lymphoma; CHIP; Carboxyl terminus of Hsc70 interacting protein; CHMP2B; charged multivesicular body

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Intravitreal Sirolimus for Noninfectious Uveitis: A Phase III Sirolimus Study Assessing Double-masKed Uveitis TReAtment (SAKURA)

Keywords: BCVA; best-corrected visual acuity; CRT; central retinal thickness; IOP; intraocular pressure; mTOR; mammalian target of rapamycin; NEI VFQ-25; 25-item National Eye Institute Visual Function Questionnaire; NIU; noninfectious uveitis; OCT; optical coherenc

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

DNA Topoisomerase IIα contributes to the early steps of adipogenesis in 3T3-L1 cells

Keywords: MCE; mitotic clonal expansion; C/EBP; CCAAT/enhancer-binding protein; PPARγ; peroxisome proliferator-activated receptor γ; IR; insulin receptor; PI3K; phosphoinositide 3-kinase; PKB; protein kinase B; Topo IIα and β; DNA Topoisomerase IIα and β; mTO

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Collagen XVII Shedding Suppresses Re-Epithelialization by Directing Keratinocyte Migration and Dampening mTOR Signaling

Keywords: ADAMs; a disintegrin and metalloproteinases; Akt; acutely transforming retrovirus AKT8 in rodent T-cell lymphoma; ECM; extracellular matrix; HD; hemidesmosome; mTOR; mechanistic target of rapamycin; PI3K; phosphoinositide 3-kinase;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Metabolic pathways in T cell activation and lineage differentiation

Keywords: T cells; Metabolism; Glycolysis; Fatty acid metabolism; mTOR; AMPK; ACC;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Pomolic acid suppresses HIF1α/VEGF-mediated angiogenesis by targeting p38-MAPK and mTOR signaling cascades

Keywords: Pomolic acid; EGF; Angiogenesis; HIF1α; VEGF; mTOR; EGF; Epidermal growth factor; EGFR; Epidermal growth factor receptor; VEGF; Vascular endothelial growth factor; HIF; hypoxia-inducible factor; HRE; hypoxia-response elements; MAPK; Mitogen-activated pro

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Research paperRapamycin safeguards lymphocytes from DNA damage accumulation in vivo

Keywords: CNI; calcineurin inhibitors; CSA; cyclosporine A; IL-2; interleukin-2; mTOR; mammalian Target Of Rapamycin; NFAT; nuclear factor of activated T cells; PBL; peripheral blood lymphocytes; PHA; phytohemagglutinin; RIN; RNA integrity; ROS; reactive oxygen spe

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewProspects for mTOR-mediated functional repair after central nervous system trauma

Keywords: mTOR; Spinal cord injury; Axogenesis; Axon regeneration; Myelination;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK

Keywords: Ciclopirox; mTOR; AMPK; TSC2; Raptor;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

CNS remyelination as a novel reparative approach to neurodegenerative diseases: The roles of purinergic signaling and the P2Y-like receptor GPR17

Keywords: Purinergic receptors; Oligodendrocytes; Remyelination; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ATX; autotaxin; CNS; central nervous system; DRG; dorsal root ganglion; EAE; experimental autoimmune encephalomyelitis; GDNF; glial cell de

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Neurofibromatosis type 1 associated low grade gliomas: A comparison with sporadic low grade gliomas

Keywords: NF1; neurofibromatosis type 1; LGG; low grade glioma; MAPK; mitogen activated protein kinase; mTOR; mammalian target of rapamycin; PA; pilocytic astrocytoma; MPNST; malignant peripheral nerve sheath tumours; GAP; GTPase-activating protein; RB; retinoblast

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Mammalian target of rapamycin controls glucose consumption and redox balance in human Sertoli cells

Keywords: mTOR; Sertoli cells; spermatogenesis; testis; rapamycin;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Synergistic antitumor activity of rapamycin and EF24 via increasing ROS for the treatment of gastric cancer

Keywords: 4E-BP-1; eukaryotic initiation factor 4E binding protein-1; ATF4; activating transcription factor 4; Bcl2; B-cell lymphoma 2; C/EBP; CAAT/enhancer binding protein; cdc-2; cyclin-dependent kinase 1 (cell division cycle protein 2); CHOP; CAAT/enhancer bindi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Decorin as a multivalent therapeutic agent against cancer

Keywords: AMPKα; AMP-activated protein kinase, alpha; AP4; Activating enhancer binding protein 4; ATG; Autophagy-related gene; Bcl2; B-cell CLL/lymphoma 2; BRAF; Proto-oncogene B-Raf; ECM; Extracellular matrix; EGFR; Epidermal growth factor receptor; ERK; Extracel

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Astemizole-Histamine induces Beclin-1-independent autophagy by targeting p53-dependent crosstalk between autophagy and apoptosis

Keywords: AST; Astemizole; HIS; Histamine; H1R; Histamine H1 receptor; ROS; Reactive oxygen species; ER; Endoplasmic reticulum; PERK; Protein kinase R-like endoplasmic reticulum kinase; IRE1α; Inositol-requiring enzyme 1; ATF; Activating transcription factor; JNK;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

The role of AMPK in cardiomyocyte health and survival

Keywords: ADP; Adenosine diphosphate; AICAR; 5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside; AMPK; Adenosine monophosphate-activated protein kinase; CaMKKβ; Calmodulin-dependent protein kinase kinase beta; CPT1; Carnitine palmitoyltransferase 1; eNOS; Endoth

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

The mTOR pathway in obesity driven gastrointestinal cancers: Potential targets and clinical trials

Keywords: mTOR; Gastrointestinal cancers; Obesity; Clinical trials

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

mTORC1 and DNA-PKcs as novel molecular determinants of sensitivity to Chk1 inhibition

Keywords: Chk1; mTOR; DNA-PKcs; V158411; Double strand break repair;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Circulating and visceral adipose miR-100 is down-regulated in patients with obesity and Type 2 diabetes

Keywords: microRNAs; Obesity; Adipogenesis; Type 2 diabetes; mTOR; IGFRaP2, adipocyte fatty acid binding protein 2; BMI, Body Mass Index; DBP, Diastolic Blood Pressure; DMEM, Dulbecco's Modified Eagle Medium; EDTA, Ethylenediaminetetraacetic acid; HDL, high-density

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of sodium tri- and hexameta-phosphate in vitro osteoblastic differentiation in Periodontal Ligament and Osteoblasts, and in vivo bone regeneration

Keywords: Sodium triphosphate; Sodium hexametaphosphate; Growth; Osteoblast; Differentiation; mTOR;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Weight Loss Upregulates the Small GTPase DIRAS3 in Human White Adipose Progenitor Cells, Which Negatively Regulates Adipogenesis and Activates Autophagy via Akt–mTOR Inhibition

Keywords: Adipogenesis; Aging; Autophagy; Caloric restriction; DIRAS3; ERK1/2; Human adipose-derived stromal/progenitor cells; IGF-1; Insulin; mTOR; Akt; Obesity; Weight loss

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportThe antidepressant-like effect of alarin is related to TrkB-mTOR signaling and synaptic plasticity

Keywords: GALP; galanin-like peptide; mTOR; mammalian target of rapamycin; TrkB; tropomyosin-related kinase B; ERK; extracellular signal-regulated kinase; AKT; protein kinase B; p70S6K; ribosomal protein S6 kinase; 4E-BP1; eukaryotic initiation factor 4E binding pr

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Non-genomic oestrogen receptor signal in B lymphocytes: An approach towards therapeutic interventions for infection, autoimmunity and cancer

Keywords: mER; membrane bound oestrogen receptor; GPER; G-protein coupled oestrogen receptor; PIP2; phosphatidylinositol 4,5-biphosphate; IP3; inositol triphosphate; PI3 kinase; phosphoinositide 3-kinase; Akt; protein kinase B a Serine/Threonine specific protein ki

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Transcriptome analysis of the molting gland (Y-organ) from the blackback land crab, Gecarcinus lateralis

Keywords: Blast2GO; Crustacea; Decapoda; Ecdysteroid; Gecarcinus; Molting; mTOR; Transforming growth factor beta; Transcriptome; Y-organ; Signal transduction; Molt-inhibiting hormone

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Autophagy in kidney disease and aging: lessons from rodent models

Keywords: acute kidney injury; aging; autophagy; endothelium; glomerulus; kidney; kidney transplantation; mTOR; podocyte; polycystic kidney disease;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Evolving Lessons on the Complex Role of AMPK in Normal Physiology and Cancer

Keywords: AMPK; cancer; mTOR; LKB1; metformin; oncogenic stress

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis

Keywords: Aβ; Amyloid β; AD; Alzheimer's disease; Akt; protein kinase B; AraC; cytosine arabinoside; ATP; adenosine triphosphate; CaM; calmodulin; CaMKIα; Ca2 +/calmodulin-dependent kinase type 1 alpha; CaMKII; Ca2 +/calmodulin-dependent kinase type II; CDK; c

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Vascular mTOR-dependent mechanisms linking the control of aging to Alzheimer's disease

Keywords: Alzheimer's; Neurovascular aging; Target of rapamycin; MTOR; Aging; Geroscience;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes

Keywords: ATGL; Adipose triglyceride lipase; CHOP; CCAAT-enhancer-binding protein homologous protein; CLEAR; coordinated lysosomal enhancement and regulation; CMA; chaperone mediated autophagy; CQ; chloroquine; eIF2α; eukaryotic translation initiation factor 2α;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

mTOR inhibition sensitizes ONC201-induced anti-colorectal cancer cell activity

Keywords: Colorectal cancer; ONC201; TRAIL; mTOR; AZD-8055;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Autophagic lysosomal reformation depends on mTOR reactivation in H2O2-induced autophagy

Keywords: ALR; autophagic lysosomal reformation; H2O2; hydrogen peroxide; Rab7; Ras-related protein 7; PI4P; phosphatidylinositol 4-phosphate; mTOR; mammalian mechanistic target of rapamycin; Atg; autophagy-related gene; DMEM; Dulbecco's Modified Eagle's Medium; EB

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2016 سفارش ترجمه

GLP-1 analogue improves hepatic lipid accumulation by inducing autophagy via AMPK/mTOR pathway

Keywords: Liraglutide; Hepatocyte steatosis; Autophagy; mTOR; AMPK;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2016 سفارش ترجمه

Oncogenic KRAS signaling and YAP1/β-catenin: Similar cell cycle control in tumor initiation

Keywords: YAP1; Yes; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; eIF4E; eukaryotic translation initiation factor 4E; PI3K; phosphatidylinositide-3-kinase; WNT; Wingless-type mouse mammary tumor virus integration site family m

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Mitochondrial translation factors reflect coordination between organelles and cytoplasmic translation via mTOR signaling: Implication in disease

Keywords: Mitochondrial translation; Mitochondrial elongation factor 4 (mtEF4); mTOR; Mitochondrial diseases;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition

Keywords: Autophagy; Mutant p53; Gain-of-function; Cancer; mTOR; AMPK;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

Development of a model describing regulation of casein synthesis by the mammalian target of rapamycin (mTOR) signaling pathway in response to insulin, amino acids, and acetate

Keywords: amino acids; mTOR; casein; insulin;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells

Keywords: 4E-BP1; 4E binding protein; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; ATP; adenosine triphosphate; DEPTOR; DEP domain containing mTOR-interacting protein; CI; complexes I; CII; complex II; CIII; complex III; CIV; complex

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Intrathecal administration of rapamycin inhibits the phosphorylation of DRG Nav1.8 and attenuates STZ-induced painful diabetic neuropathy in rats

Keywords: STZ; streptozotocin; PDN; painful diabetic neuropathy; DRG; dorsal root ganglion; mTOR; mammalian target of rapamycin; S6K; ribosomal protein S6 kinase; 4E-BP; eukaryotic initiation factor 4E (eIF4E) binding protein; IR; insulin receptor; IRS-1; insulin r

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Polymerase delta-interacting protein 2 regulates collagen accumulation via activation of the Akt/mTOR pathway in vascular smooth muscle cells

Keywords: Akt; protein kinase B; Atg; autophagy-related gene; ECM; extracellular matrix; 4E-BP1; eukaryotic initiation factor 4E binding protein 1; eIF4E; eukaryotic translation initiation factor 4E; Hsc70; heat shock cognate protein 70; LC3B; microtubule-associate

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه

FGFR antagonist induces protective autophagy in FGFR1-amplified breast cancer cell

Keywords: Breast cancer; FGFR; PD166866; Autophagy; mTOR;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Uroguanylin modulates (Na+ + K+)ATPase in a proximal tubule cell line: Interactions among the cGMP/protein kinase G, cAMP/protein kinase A, and mTOR pathways

Keywords: UGN; uroguanylin; PT; proximal tubule; GFR; glomerular flow rate; NHE3; Na+/H+ exchanger isoform 3; PKA; protein kinase A; PKG; protein kinase G; Gi; inhibitory G protein; PKB; protein kinase B; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

The collagen derived dipeptide hydroxyprolyl-glycine promotes C2C12 myoblast differentiation and myotube hypertrophy

Keywords: Differentiation; Myoblast; Myotube; Collagen peptide; Hydroxyprolyl-glycine; Hypertrophy; DMEM; Dulbecco's modified Eagle's medium; Hyp; hydroxyproline; Hyp-Gly; hydroxyprolyl-glycine; IGF-1; insulin-like growth factor 1; mTOR; mammalian target of rapamyc

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Performance of a phosphoflow assay to determine phosphorylation of S6 ribosomal protein as a pharmacodynamic read out for mTOR inhibition

Keywords: Akt; protein kinase B; BSA; bovine serum albumin; CRP; C-reactive protein; CsA; cyclosporine A; CV; coefficient of variation; EDTA; ethylenediaminetetraacetic acid; ELISA; enzyme-linked, immunosorbent assay; ERK; extracellular signal-regulated kinase; Evr

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

Negative regulation of the FOXO3a transcription factor by mTORC2 induces a pro-survival response following exposure to ultraviolet-B irradiation

Keywords: mTOR; mammalian target of rapamycin; UVB; ultraviolet-B; NMSC; non-melanoma skin cancer; mTORC1; mTOR complex 1; mTOC2; mTOR complex 2; AKT/PKB; protein kinase B; SCC; squamous cell carcinoma; ERK; extracellular-signal-regulated kinases; MEK; mitogen-acti

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Unravelling exemestane: From biology to clinical prospects

Keywords: AI(s); aromatase inhibitor (s); AKT; protein kinase B; AREG; amphiregulin; BMD; bone mineral density; CYP; cytochrome P450; DHEAS; dehydroepiandrosterone sulfate; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; EMA; European Medicine

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

mTOR, cardiomyocytes and inflammation in cardiac hypertrophy

Keywords: Protein synthesis; Protein degradation; mTOR; NF-kappaB; Inflammation; Cardiomyocyte;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه