دانلود مقالات ISI درباره Mtor + ترجمه فارسی

Liver cancer: From molecular pathogenesis to new therapies

Keywords: DEB; drug-eluting bead; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; hTERT; human telomerase reverse transcriptase; PDGF; platelet derived growth factor; FAK; focal adhesion kinase; Pyk2; proline-rich tyrosine kinase 2; M

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Rapamycin Inhibits Proliferation and Migration of Hepatoma Cells In Vitro

Keywords: mTOR; rapamycin; Akt; liver transplantation; hepatocellular carcinoma; metastasis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Combinations of mTORC1 inhibitor RAD001 with gemcitabine and paclitaxel for treating non-Hodgkin lymphoma

Keywords: RAD001; Gemcitabine; Paclitaxel; Non-Hodgkin lymphoma; mTOR

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Smad3-dependent and -independent pathways are involved in peritoneal membrane injury

Keywords: adenovirus; angiogenesis; fibrosis; mTOR; peritoneum; rapamycin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Challenging Clinical Scenarios: Treatment of Patients With Triple-Negative or Basal-Like Metastatic Breast Cancer

Keywords: Angiogenesis inhibitors; BRCA1; Monoclonal antibodies; mTOR; PARP inhibitors

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: A crucial role of AMPK and mTOR pathways

Keywords: Antroquinonol; Hepatocellular carcinoma; AMPK; mTOR; G1 arrest

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

The DTH effector response and IL-2 are unaffected by cyclosporine A in autoimmune B6D2F1 mice

Keywords: IL-2; Delayed-type hypersensitivity; Cyclosporine A; Cell signaling; Costimulation; T cells; Cytokines; mTOR; Temsirolimus; CTLA-4

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Pain Mechanisms and Sensory NeuroscienceResearch PaperMammalian target of rapamycin in spinal cord neurons mediates hypersensitivity induced by peripheral inflammation

Keywords: mTOR; rapamycin; pain; spinal cord; inflammation; carrageenan; AUC; area under the curve; BDNF; brain-derived neurotrophic factor; DMEM; Dulbecco's modified eagle medium; DRG; dorsal root ganglion; EDTA; ethylenediaminetetraacetic acid; ERK; extracellular

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Mammalian target of rapamycin (mTOR) regulates TLR3 induced cytokines in human oral keratinocytes

Keywords: Human oral keratinocytes; TLR3; mTOR; JNK; NF-κB; IRF3

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Research ArticleRelevance of the mTOR signaling pathway in the pathophysiology of splenomegaly in rats with chronic portal hypertension

Keywords: mTOR; mammalian target of rapamycin; VEGF; vascular endothelial growth factor; VEGFR-2; VEGF receptor-2; PDGFR-β; platelet-derived growth factor receptor-β; TNF-α; tumor necrosis factor-α; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; 4E-BP1; eukar

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Triptolide Induces Cell Death in Pancreatic Cancer Cells by Apoptotic and Autophagic Pathways

Keywords: Autophagy; Apoptosis; Pancreatic Cancer; Cell Death; Akt; Protein Kinase B; ERK; Extracellular Signal-Related Kinase; Hsp; heat shock protein; LC; Light chain; mTOR; mammalian target of Rapamycin; siRNA; short interfering RNA;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Mammalian target of rapamycin is a biomarker of poor survival in metastatic serous ovarian carcinoma

Keywords: AKT; mTOR; DJ-1; Serous ovarian carcinoma; Effusions; Survival

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Receptor tyrosine kinase and downstream signalling analysis in diffuse malignant peritoneal mesothelioma

Keywords: Diffuse malignant peritoneal mesothelioma; EGFR; PDGFRB; p16; mTOR

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Pancreatic cancer stem cells – update and future perspectives

Keywords: Pancreatic cancer; Stem cells; Cancer stem cells; Tumour-initiating cell; metastasis; mTOR; Hedgehog; Gemcitabine; Targeted therapy

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: An in vivo bioluminescence imaging study

Keywords: Triple-negative breast cancer; Breast cancer metastasis; in vivo bioluminescence imaging; Rapamycin; mTOR; Cyclophosphamide; HIF-1α;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Loss of Single Immunoglobulin Interlukin-1 Receptor-Related Molecule Leads to Enhanced Colonic Polyposis in Apcmin Mice

Keywords: TIR8; Cyclin D1; c-Myc; Stat3; Apc; adenomatous polyposis coli; 4EBP; 4E binding protein; GSK3β; glycogen synthase kinase 3β; IL; interleukin; IL-1R; interleukin-1 receptor; LOH; loss of heterozygosity; LPS; lipopolysaccharide; mTOR; mammalian target of

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Increased levels of p70S6 phosphorylation in the G93A mouse model of Amyotrophic Lateral Sclerosis and in valine-exposed cortical neurons in culture

Keywords: Valine; Action potential; Persistent sodium current; mTOR; Cortex; Electrophysiology

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Role of Somatostatins in Gastroenteropancreatic Neuroendocrine Tumor Development and Therapy

Keywords: Somatostatin Analogs; Somatostatin Receptors; Peptide Radio Receptor Therapy; DOTATOC; [DOTA0,Tyr3]-octreotide; DOTATATE; [DOTA0,Tyr3,Thr8]-octreotide; DTPA; diethylenetriaminepentaacetic acid; GEP-NET; gastroenteropancreatic neuroendocrine tumor; IFN; in

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Secreted phosphoprotein 1 binds integrins to initiate multiple cell signaling pathways, including FRAP1/mTOR, to support attachment and force-generated migration of trophectoderm cells

Keywords: Secreted phosphoprotein 1; Integrins; mTOR; Implantation; Mitogen activated protein kinases; Trophectoderm

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Pharmacodynamic Characterization of the Efficacy Signals Due to Selective BRAF Inhibition with PLX4032 in Malignant Melanoma

Keywords: AKT; v-akt murine thymoma viral oncogene homolog; ANOVA; analysis of variance; ATCC; American Type Culture Collection; BRAF; v-raf murine sarcoma viral oncogene homolog B1; BRAFm; BRAF mutation; CKIT; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Angiogenesis and Current Antiangiogenic Strategies for the Treatment of Cancer

Keywords: bFGF; basic fibroblast growth factor; DLL4; Notch ligand delta-like 4; ERK; extracellular signal-regulated kinase; FDA; Food and Drug Administration; HIF; hypoxia-inducible factor; MAPK; mitogen-activated protein kinase; MMP; matrix metalloproteinase; m

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2010 سفارش ترجمه

The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine

Keywords: Hexosamine; Insulin; Growth factor; O-GlcNAc; Neurodegeneration; Cancer; Diabetes; Cardiovascular disease; mTOR; AMPK; AKT; MAPK

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Cardiac overexpression of insulin-like growth factor 1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction but not hypertrophy: Roles of Akt, mTOR, GSK3β, and PTEN

Keywords: Alcohol; Cardiac hypertrophy; Contractile function; Intracellular Ca2+; Akt; mTOR; GSK3β; Foxo3a; Free radicals

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

ATP-mediated protein kinase B Akt/mammalian target of rapamycin mTOR/p70 ribosomal S6 protein p70S6 kinase signaling pathway activation promotes improvement of locomotor function after spinal cord injury in rats

Keywords: mTOR; rapamycin; signal transduction pathway; locomotor functional recovery; spine; nervous system injury; Akt; protein kinase B; BBB; Basso-Beattie-Bresnahan; BSA; bovine serum albumin; CNS; central nervous system; DAB; 3,3-diaminobenzidine; GAPDH; g

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2010 سفارش ترجمه

Adiponectin Modulates C-Jun N-Terminal Kinase and Mammalian Target of Rapamycin and Inhibits Hepatocellular Carcinoma

Keywords: Hepatocellular Carcinoma; Adiponectin; TSC2; mTOR; AMPK; adenosine monophosphate−activated protein kinase; BMI; body mass index; HCC; hepatocellular carcinoma; JNK; c-Jun-N-terminal kinase; mTOR; mammalian target of rapamycin; TMA; tissue microarray; TS

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2010 سفارش ترجمه

Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders

Keywords: Apoptosis; Brain-derived neurotrophic factor (BDNF); Glycogen synthase kinase 3 (GSK-3); Lithium; Neurodegenerative diseases; Neuroprotection; 3-NP; 3-nitropropionic acid; Aβ; β-amyloid; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AP-1;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2010 سفارش ترجمه

The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients

Keywords: AAIR; atrium paced, atrium sensed inhibited rate modulation; ACC; American College of Cardiology; ACEI; angiotensin converting enzyme inhibitor; ACT; activated clotting time; ADA; American Diabetes Association; AHA; American Heart Association; AMR; antibo

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2010 سفارش ترجمه

Cross-talk between adipose and gastric leptins for the control of food intake and energy metabolism

Keywords: ACTH; adrenocorticotropic hormone; ADIPOR1/2; adiponectin receptor1/2; AgRP; agouti related protein; AMPK; AMP-activated protein kinase; BSDL; bile salt-dependent lipase; cAMP; cyclic adenosine-monophosphate; CART; cocaine amphetamine related transcript;

دانلود رایگان متن کامل مقاله ISI 58 صفحه سال انتشار : 2010 سفارش ترجمه

The discovery and optimisation of pyrido[2,3-d]pyrimidine-2,4-diamines as potent and selective inhibitors of mTOR kinase

Keywords: Antitumour; mTOR; Serine/threonine kinase

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Identification and optimisation of novel and selective small molecular weight kinase inhibitors of mTOR

Keywords: Mammalian target of rapamycin; mTOR; Kinase inhibitors; Phosphatidylinositol 3-kinase; PI3K

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Evaluation of in vivo antineoplastic effects of rapamycin in patients with chemotherapy-refractory AML

Keywords: AML; Chemotherapy resistance; Rapamycin; mTOR

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential

Keywords: Nephropathy; Rapamycin; Diabetes; mTOR; S6kinase

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

ATF4 is necessary and sufficient for ER stress-induced upregulation of REDD1 expression

Keywords: REDD1; Rtp801; mTOR; ER stress; PERK; ATF4;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Rapamycin inhibits poly(ADP-ribosyl)ation in intact cells

Keywords: Rapamycin; mTOR; Poly(ADP-ribosyl)ation; PARP inhibitor; Fibroblasts;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Deregulation of mTOR signaling is involved in thymic lymphoma development in Atm−/− mice

Keywords: A-T; ATM; Thymocyte; Thymic lymphoma; c-Myc; mTOR; 4EBP1; Cyclin D1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Down-regulation of mTOR leads to up-regulation of osteoprotegerin in bone marrow cells

Keywords: mTOR; Osteoprotegerin; ST2; RANKL; Osteoblast

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Common mechanisms of PIKK regulation

Keywords: ATR; ATM; DNA-PK; mTOR; SMG1; PIKK

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Caffeic acid phenethyl ester accumulates β-catenin through GSK-3β and participates in proliferation through mTOR in C2C12 cells

Keywords: Akt; β-catenin; CAPE; GSK-3β; mTOR

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Class IA Phosphatidylinositol 3-Kinase Signaling in Non-small Cell Lung Cancer

Keywords: Phosphatidylinositol-3 Kinase; AKT; mTOR; NSCLC;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Late progression of renal pathology and cyst enlargement is reduced by rapamycin in a mouse model of nephronophthisis

Keywords: mTOR; nephronophthisis; rapamycin; renal cysts

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Enhanced interaction between Hsp90 and raptor regulates mTOR signaling upon T cell activation

Keywords: mTOR; Raptor; Hsp90; T cell; Anergy; Rapamycin

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Ribavirin enhances interferon signaling via stimulation of mTOR and p53 activities

Keywords: Ribavirin; mTOR; p53; IFN

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

The serine 2481-autophosphorylated form of mammalian Target Of Rapamycin (mTOR) is localized to midzone and midbody in dividing cancer cells

Keywords: mTOR; Cell cycle; Mitosis; Cytokinesis; Chromosomal passenger protein; Cancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Treatment Algorithms in Metastatic Renal Cell Carcinoma, Including the Potential Role of the Novel Oral Mammalian Target of Rapamycin Inhibitor Everolimus

Keywords: Everolimus; First-line; mTOR; Renal cell carcinoma; Second-line; Treatment algorithms; VEGF-targeted therapy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Effects of PI3K catalytic subunit and Akt isoform deficiency on mTOR and p70S6K activation in myoblasts

Keywords: PI3K; Akt; mTOR; S6K; MyoblastPI3K, phosphoinositide 3-kinase; mTOR, mammalian target of rapamycin; p70S6K, 70 kDa ribosomal protein S6 kinase; IGF-I, insulin-like growth factor-I; PRAS40, proline-rich Akt substrate of 40 kDa

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Molecular Pathways in Metastatic Renal Cell Carcinoma: The Evolving Role of Mammalian Target of Rapamycin Inhibitors

Keywords: Everolimus; Hypoxia-inducible factors; mTOR; Metastatic renal cell carcinoma; Molecular pathways; Temsirolimus; von Hippel-Lindau

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Silencing of secretory clusterin sensitizes NSCLC cells to V-ATPase inhibitors by downregulating survivin

Keywords: AKT; Clusterin; mTOR; PI3K; Survivin; V-ATPase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Incorporation of water-solubilizing groups in pyrazolopyrimidine mTOR inhibitors: Discovery of highly potent and selective analogs with improved human microsomal stability

Keywords: mTOR; PI3K; Kinase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Regulation of folliculin (the BHD gene product) phosphorylation by Tsc2-mTOR pathway

Keywords: FLCN; Tsc2; BHD; mTOR; AMPK; S6K; Phosphorylation; Rheb;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

FGFR1 forms an FRS2-dependent complex with mTOR to regulate smooth muscle marker gene expression

Keywords: FGFR1; FRS2; mTOR; Rapamycin; SM α-actin; VSMC;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه