Hydrothermal stability of MTT zeolite in hot water: The role of La and Ce
Keywords: MTT; MTT; Hydrothermal stability; Lanthanum; Cerium; Hot water
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Differences in protein binding and excretion of Triapine and its Fe(III) complex
Keywords: MTT; Drug development; Thiosemicarbazones; Triapine; Pharmacokinetics; In vivo; 5-HP; 5-hydroxypicolinaldehyde thiosemicarbazone; DMSO; dimethyl sulfoxide; dNTP; deoxynucleoside triphosphate; Dp44mT; di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone; EIC; e
Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer
Keywords: MTT; Epigenetic inhibitors; Prostate cancer; Kidney cells; Nephrotoxicity; 5-Aza; 5-aza-2ʹ-deoxycytidine; CBZ; carbamazapine; CDK; cyclin-dependent kinase; CDKN1a; cyclin-dependent kinase inhibitor 1a; CFZ; carfilzomib; ChIP; chromatin immunoprecipitation; DM
Lonicerae Japonicae Flos attenuates diabetic retinopathy by inhibiting retinal angiogenesis
Keywords: MTT; FL; aqueous extract of Lonicerae Japonicae Flos; STZ; streptozotocin; DR; diabetic retinopathy; PDR; proliferative DR; CD31; cluster of differentiation 31; ELISA; enzyme-linked immunosorbent assay; VEGF; vascular endothelial growth factor; MTT; 3-(4, 5-di
Protective effect of kaempferol, a flavonoid widely present in varieties of edible plants, on IL-1β-induced inflammatory response via inhibiting MAPK, Akt, and NF-κB signalling in SW982 cells
Keywords: MTT; Kaempferol; Inflammatory mediator; Signalling pathway; SW982 cells; COX; cyclooxygenase; MMP; matrix metallo proteinase; RA; rheumatoid arthritis; TNF-α; tumour necrosis factor-α; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; AMPK;
Original ArticleThe A2b adenosine receptor antagonist PSB-603 promotes oxidative phosphorylation and ROS production in colorectal cancer cells via adenosine receptor-independent mechanism
Keywords: MTT; PSB603; Off-target effect; Cellular redox state; Reactive oxygen species; Chemotherapy; MTT; 5-FU; Fluorouracil; AR(s); Adenosine receptor(s); CRC; Colorectal cancer; ECAR; extracellular acidification rate; gRNA; guide RNA; HBSS; Hank's Balanced Saline So
The adjuvanticity of ophiopogon polysaccharide liposome against an inactivated porcine parvovirus vaccine in mice
Keywords: MTT; PPV; porcine parvovirus; OPL; ophiopogon polysaccharide liposome; OP; ophiopogon polysaccharide; HI; haemagglutinin inhibition; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PBS; phosphate buffered saline; PHA; phytohaemagglutinin; LP
Tumor suppression effect of Solanum nigrum polysaccharide fraction on Breast cancer via immunomodulation
Keywords: MTT; SN-ppF3; Solanum nigrum polysaccharide fraction number 3; FT-IR; Fourier Transform Infrared; CTX; cyclophosphamide; ELISA; enzyme-linked immunosorbent assay; DMEM; Dulbeccoâ¿¿s modified eagle medium; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoli
Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by β2-agonists, corticosteroids, and critical illness
Keywords: MTT; Neutrophil; β2-agonist; cyclic AMP; exchange protein directly activated by cyclic AMP; hospital-acquired infection; AKAP; A kinase anchoring protein; BALTI-2; Beta Agonist Lung Injury Trial-2; cAMP; Cyclic AMP; EPAC; Exchange protein directly activated b
Toxicity and oxidative stress induced by T-2 toxin and HT-2 toxin in broilers and broiler hepatocytes
Keywords: MTT; T-2 and HT-2 toxin; Broilers; Hepatocytes; Toxicity; Oxidative stress; T-2; T-2 toxin; HT-2; HT-2 toxin; GSH; glutathione; LDH; lacate dehydrogenase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ROS; reactive oxygen species; GSH-PX; glu
TLR-4 may mediate signaling pathways of Astragalus polysaccharide RAP induced cytokine expression of RAW264.7 cells
Keywords: MTT; APC; Antigen presenting cells; LPS; Lipopolysaccharide; PRRs; Pattern-recognition receptors; TLRs; Toll-like receptors; TLR4; Toll-like receptor 4; RAP; Radix Astragali polysacchairdes; RT-PCR; Real time-polymerase chain reaction; MTT; 3-(4,5-dimethylthia
Iron gene expression profile in atherogenic Mox macrophages
Keywords: MTT; acLDL; acetylated LDL; ApoEâ/â; Â cells or mice deficient in the gene coding for apolipoprotein E; ATH; atherosclerosis; BMDM; bone marrow-derived macrophages; CP/Cp; ceruloplasmin (gene Cp); EDTA; ethylenediaminetetraacetic acid; ffe; flat iron mutat
Peroxisome proliferator-activated receptor-γ (PPARγ) agonist is neuroprotective and stimulates PGC-1α expression and CREB phosphorylation in human dopaminergic neurons
Keywords: MTT; PPARγ; PGC-1α; SIRT1; CREB; Dopaminergic neurons; Mitochondria; AC6; adenylyl cyclase 6; CRE; cAMP responsive element; CREB; cAMP responsive element-binding protein; FCCP; carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone; GW1929; N-(2-benzoylphenyl)
Cytotoxicity assessment of lipid-based self-emulsifying drug delivery system with Caco-2 cell model: Cremophor EL as the surfactant
Keywords: MTT; LBDDS; Lipid-based drug delivery system; LBSEDDS; Lipid-based self-emulsifying drug delivery system; SEDDS; Self-emulsifying drug delivery system; SMEDDS; Self-microemulsifying drug delivery system; MTT; (3-(4.5-Dimethylthiazol-2-yl)-2.5-diphenyltetrazoli
Pure Î9-tetrahydrocannabivarin and a Cannabis sativa extract with high content in Î9-tetrahydrocannabivarin inhibit nitrite production in murine peritoneal macrophages
Keywords: MTT; BSA; albumin bovine serum; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CBC; cannabichromene; CBD; cannabidiol; CBG; cannabigerol; COX-2; cyclooxygenase-2; DAN; 2,3-diaminonaphthalene; DMSO; dimethyl sulfoxide (DMSO); DTT; 1,4-dithi
Glucose dithiocarbamate derivatives as capping ligands of water-soluble CdSeS/ZnS quantum dots
Keywords: MTT; βDG-SH; 1-thio-β-d-glucose; DEA; diethanolamine; DG; d-glucosamine hydrochloride; DG-DTC; d-glucosamine dithiocarbamate; DMSO; dimethyl sulfoxide; DTCs; dithiocarbamates; FBS; fetal bovine serum; Gly; glycine; IDA; iminodiacetic acid; MEA; ethanolamine;
Cardiac atrial appendage stem cells promote angiogenesis in vitro and in vivo
Keywords: MTT; ALDH; aldehyde dehydrogenase; ANG; angiogenin; Ang-1; angiopoietin-1; CAM; chorioallantoic membrane; CASC; cardiac atrial appendage stem cell; CM; conditioned medium; CSC; cardiac stem cell; DAPI; 4â²,6-diamidino-2-phenylindole; DPPIV; dipeptidyl peptida
Recombinant Reg3α protein protects against experimental acute pancreatitis in mice
Keywords: MTT; Acute pancreatitis; Reg3α protein; l-arginine; Pancreatic acini; Necrosis; PMSF; phenylmethylsulfonyl fluoride; PBS; phosphate buffered saline; PVDF; polyvinylidene fluoride; TBST; tris-buffered saline and tween 20; MTT; (3-(4, 5-Dimethyl-2-thiazolyl)-2,
SARM modulates MyD88-mediated TLR activation through BB-loop dependent TIR-TIR interactions
Keywords: MTT; ANTP; Antennapedia homeodomain; AP-1; activator protein 1; CV; column volume; DAPI; 4â²-6-diamidino-2-phenylindole; DIC; differential interference contrast; DMEM; Dulbecco's Modified Eagle Medium; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic aci
Estrogenic activity of isoflavonoids from the stem bark of the tropical tree Amphimas pterocarpoides, a source of traditional medicines
Keywords: MTT; AlkP; alkaline phosphatase; BW; body weight; ERα; estrogen receptor α; ERβ; estrogen receptor β; ERE; estrogen response element; E2; estradiol; EGF; epidermal growth factor; HPLC-DAD; high pressure liquide chromatography with diode-array detection; HR
Propofol but not sevoflurane prevents mitochondrial dysfunction and oxidative stress by limiting HIF-1α activation in hepatic ischemia/reperfusion injury
Keywords: MTT; I/R; ischemia/reperfusion; ROS; reactive oxygen species; SEVO; sevoflurane; PROP; propofol; PTP; permeability transition pore; HIF-1α; hypoxia-inducible factor 1 alpha; DFX; deferoxamine; ALT; alanine aminotransferase; AST; aspartate aminotransferase; GS
Galactose conjugated platinum(II) complex targeting the Warburg effect for treatment of non-small cell lung cancer and colon cancer
Keywords: MTT; Galactose-Pt(II) conjugate; Glucose transporter; Warburg effect; Maximum tolerated dose; Antitumor efficacy; GLUTs; glucose transporters; Gal-Pt; galactose-conjugated 2-chloromalonatoplatinum(II) complex; Oxa; oxaliplatin; Que; quercetin; 5-FU; 5-fluorour
Theanine from tea and its semi-synthetic derivative TBrC suppress human cervical cancer growth and migration by inhibiting EGFR/Met-Akt/NF-κB signaling
Keywords: MTT; TBrC; ethyl 6-bromocoumarin-3-carboxylyl l-theanine; BrC; ethyl 6-bromocoumarin-3-carboxylic acid; NF-κB; nuclear factor κB; HGF; hepatocyte growth factor; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; EZH2; enhancer of zeste hom
Amaranth peptides with antithrombotic activity released by simulated gastrointestinal digestion
Keywords: MTT; Amaranth protein isolate; Gastrointestinal digestion; Antithrombotic activity; Absorption by Caco 2 cell culture; Bioactive peptides; TEER; transepithelial electrical resistance; DH%; degree of hydrolysis; MTT; methyl tetrazolium assay; AF; active fractio
Hypolipidaemic function of Hsian-tsao tea (Mesona procumbens Hemsl.): Working mechanisms and active components
Keywords: MTT; Mesona procumbens Hemsl; Hsian-tsao; hypolipidaemia; HepG2 cells; MAPK; AMPK; ACC; acetyl-CoA carboxylase; AD; an atherogenic diet without HT; ADH; an atherogenic diet with a high dose of HT; ADL; an atherogenic diet with a low dose of HT; AMPK; 5â² AMP-
Modulation of glycolysis and lipogenesis by novel PI3K selective molecule represses tumor angiogenesis and decreases colorectal cancer growth
Keywords: MTT; PI3K signaling; Quinazolinone; Warburg effect; Lipogenesis; Angiogenesis; DHNQ; 2, 3-Dihydro-2-(naphthalene-1-yl) quinazolin-4(1H)-one; MTT; 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PI3K; Phosphatidylinositol 3-kinase;
Comparable reduction in Zif268 levels and cytochrome oxidase activity in the retrosplenial cortex following mammillothalamic tract lesions
Keywords: MTT; ANOVA; Analysis of variance; AP; antero-posterior; DV; dorso-ventral; LM; lateral-medial; MTT; mammillothalamic tract; Rdg; retrosplenial dysgranular cortex; Rga; retrosplenial granular a cortex; Rgb; retrosplenial granular b cortex; diencephalic amnesia;
Inhibition of autophagy promotes apoptosis and enhances anticancer efficacy of adriamycin via augmented ROS generation in prostate cancer cells
Keywords: MTT; ADM; adriamycin; ADT; androgen deprivation therapies; CQ; chloroquine; CRPA; castration-resistant prostate cancer; DCFH-DA; 2â²,7â²-dichlorofluorescein diacetate; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; FBS; fetal bovine seru
Remote loading of doxorubicin into liposomes by transmembrane pH gradient to reduce toxicity toward H9c2 cells
Keywords: MTT; Liposomes; Doxorubicin; Encapsulation; H9c2 cell; MTT
Stress Test of Contrast-Enhanced US with Phenylephrine in a Rabbit VX2 Liver Tumor Model: Differentiating Benign Periablational Enhancement from Residual Tumor after Radiofrequency Ablation
Keywords: MTT; AUC; area under curve; BPE; benign periablational enhancement; HCC; hepatocellular carcinoma; IMAX; maximum intensity; mTT; mean transit time; MVD; microvessel density; RF; radiofrequency; ROI; region of interest; RT; rise time; TIC; time-intensity curv
Research paperExpression of the thioredoxin system in an in vivo-like cancer cell environment upon auranofin treatment
Keywords: MTT; 2D; 2 dimensional; 3D; 3 dimensional; AUC; area under curve; ECM; extracellular matrix; ELISA; enzyme-linked immunosorbent assay; FBS; fetal bovine serum; HO-1; heme oxygenase-1; IH; intermittent hypoxia; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetr
Minocycline, a putative neuroprotectant, co-administered with doxorubicin-cyclophosphamide chemotherapy in a xenograft model of triple-negative breast cancer
Keywords: MTT; AC; adriamycin-cytoxan; CICI; chemotherapy-induced cognitive impairment; DCX; doublecortin; IHC; immunohistochemistry; MTT; methylthiazol tetrazolium; TNBC; triple-negative breast cancer; Triple-negative breast cancer; Minocycline; Chemotherapy; Chemother
A novel quinazolinone chalcone derivative induces mitochondrial dependent apoptosis and inhibits PI3K/Akt/mTOR signaling pathway in human colon cancer HCT-116Â cells
Keywords: MTT; Quinazolinone-chalcone; Apoptosis; PI3K/Akt/mTOR; Sarcoma-180; QC; Quinazolinone-chalcone; ÎÏm; mitochondrial membrane potential; MTT; 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide; PI; propidium iodide; PTP; mitochondrial permeability t
The neuroprotective effects and possible mechanism of action of a methanol extract from Asparagus cochinchinensis: In vitro and in vivo studies
Keywords: MTT; AC; Asparagus cochinchinensis; BCT; body core temperature; bFGF; basic fibroblast growth factor; BDNF; brain-derived neurotrophic factor; DIV; days in vitro; ErK; extracellular signal-related kinase; GR; glucocorticoid receptor; Imi; imipramine; MCAO; mid
Formulation and in vitro evaluation of polymeric enteric nanoparticles as dermal carriers with pH-dependent targeting potential
Keywords: MTT; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; H2DCFDA; 6-carboxy-2â²,7â²-dichlorodihydrofluorescein diacetate; DLS; dynamic light scattering; Kps; kilo count rate per second; NHDFs; normal human dermal fibroblasts; PDI; polydispersi
Synergistic antitumor activity of rapamycin and EF24 via increasing ROS for the treatment of gastric cancer
Keywords: MTT; 4E-BP-1; eukaryotic initiation factor 4E binding protein-1; ATF4; activating transcription factor 4; Bcl2; B-cell lymphoma 2; C/EBP; CAAT/enhancer binding protein; cdc-2; cyclin-dependent kinase 1 (cell division cycle protein 2); CHOP; CAAT/enhancer bindi
Nanoparticle-mediated siRNA delivery assessed in a 3D co-culture model simulating prostate cancer bone metastasis
Keywords: MTT; DHT; dehydrothermal; MMP9; matrix metalloproteinase 9; MTT; 3-(4,5dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NF-κB; nuclear factor-κB; nHA; nanohydroxyapatite; PLK1; polio-like kinase 1; siRNA; small interfering RNA; Prostate cancer cells; O
Polymeric prodrug of bufalin for increasing solubility and stability: Synthesis and anticancer study in vitro and in vivo
Keywords: MTT; Bufalin; Poly(ethylene glycol); Esterase; Maleic anhydride; Succinic anhydride; n-Propyl mercaptan; MTT; ,N'-Dicyclohexylcarbodiimide; 4-Dimethylaminopyridine; 4,6-Diamidino-2-phenylindole; Bufalin; Polymeric prodrug; Esophagus cancer;
Sub-lethal concentrations of CdCl2 disrupt cell migration and cytoskeletal proteins in cultured mouse TM4 Sertoli cells
Keywords: MTT; AIDA; Advanced Image Data Analyser; BSA; bovine serum albumin; CdCl2; cadmium chloride; CFSE; carboxyfluorescein diacetate succinimidyl ester; DAPI; 4â²,6-diamidino-2-phenylindole; DMSO; dimethyl sulfoxide; FITC; fluorescein isothiocyanate; H and E; haem
Potential antihyperglycaemic effect of myricetin derivatives from Syzygium malaccense
Keywords: MTT; 2-NBDG; 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose; AdipoQ; adiponectin, C1Q and collagen domain containing; Akt1; RAC-alpha serine/threonine-protein kinase or thymoma viral proto-oncogene 1; CAT; catalase; DM; diabetes mellitus; DIM; d
Spirostanol saponins from Chinese onion (Allium chinense) exert pronounced anti-inflammatory and anti-proliferative activities
Keywords: MTT; Chinese onion; Allium chinense; Spirostanol saponins; Anti-inflammatory; Antiproliferative; Laxogenin (PubChem CID: 10950057); Neogitogenin (PubChem CID: 44630243); A549; human lung cancer cells; CNE-1; human nasopharyngeal carcinoma; DEPT; distortionless
In vitro prion-like behaviour of TDP-43 in ALS
Keywords: MTT; pTDP-43; phosphorylated TDP-43; IF; Immunofluorescence; WB; Western blotting; SS; Sarkosyl soluble; SI; Sarkosyl Insoluble; FL WT; Full length wild type TDP-43 plasmid; NC; Normal control; FCX; Frontal cortex; MC; Motor cortex; TCX; Temporal cortex; SC L;
Potential of aqueous extract of saffron (Crocus sativus L.) in blocking the oxidative stress by modulation of signal transduction in human vascular endothelial cells
Keywords: MTT; Inflammation; Oxidative stress; micro-RNA; AKT1; PTEN; Saffron; Crocin (PubChem CID: 5281233); 2,2-Azobis (2-amidinopropane) dihydrochloride (AAPH) (PubChem CID: 84924); Tert-butylhydroperoxide (TBHP) (PubChem CID: 8033); 2,2-Diphenyl-1-(2,4,6-trinitrophe
The Chilean wild raspberry (Rubus geoides Sm.) increases intracellular GSH content and protects against H2O2 and methylglyoxal-induced damage in AGS cells
Keywords: MTT; ABTS; 2,2â²-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid diammonium salt; AGS; human gastric epithelial adenocarcinoma cells; CE; cyanidin equivalents; DAD; diode array detection; DPPH; 2,2-diphenyl-1-picryl hydrazyl; ESI; electrospray ionization; FB
Assessment of cosmetic ingredients in the in vitro reconstructed human epidermis test method EpiSkin⢠using HPLC/UPLC-spectrophotometry in the MTT-reduction assay
Keywords: MTT; CAS RN; Chemical Abstract Service Registry Number; R2; coefficient of determination; Cat. 1; Category 1; Cat. 2; Category 2; EIT; eye irritation test; DG SANCO; European Commission Directorate General for Health and Consumer Protection; EURL ECVAM; Europe
Momordin Ic couples apoptosis with autophagy in human hepatoblastoma cancer cells by reactive oxygen species (ROS)-mediated PI3K/Akt and MAPK signaling pathways
Keywords: MTT; HepG2; human hepatoblastoma; ROS; reactive oxygen species; 3-MA; 3-methyladenine; RAP; rapamycin; NAC; NAcetyl-l-cysteine; PARP; poly (ADP-ribose) polymerase; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; MDC; Monodansylcadaverine; MM
Critical role for cytosolic group IVA phospholipase A2 in early adipocyte differentiation and obesity
Keywords: MTT; ADM; adipogenic differentiation medium; AA; arachidonic acid; cPLA2α; cytosolic group IVA phospholipase A2α; MCE; mitotic clonal expansion; ASCs; adipose stem cell; MEFs; mouse embryonic fibroblast; HFD; high fat diet; MTT; 3-(4.5-dimethylthiazol-2-yl)-
Effects of prostaglandin E2 on cells cultured from the rat organum vasculosum laminae terminalis and median preoptic nucleus
Keywords: MTT; [Ca2+]i; intracellular calcium concentration; ANOVA; analysis of variance; COX-2; cyclooxygenase-2; EDTA; ethylenediaminetetraacetic acid; GABA; gamma amino butyric acid; HBSS; Hanks Balanced Salt Solution; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulf
The hyaluronic acid inhibitor 4-methylumbelliferone is an NSMase2 activator-role of Ceramide in MU anti-tumor activity
Keywords: MTT; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethylsulfoxide; fro; fragilis ossium; HA; hyaluronic acid; HAS; HA synthase; HPTLC; high performance thin-layer chromatography; LC-MS/MS; liquid chromatography-tandem mass spectrometry; MES; 2-(N-morp
Copper-zinc-superoxide dismutase (CuZnSOD), an antioxidant gene from seahorse (Hippocampus abdominalis); molecular cloning, sequence characterization, antioxidant activity and potential peroxidation function of its recombinant protein
Keywords: MTT; Antioxidant; CuZnSOD; Flow cytometry; MTT; Peroxidation