Keywords: SRCT مشاهده; Neuroblastoma; Targeted therapy; Investigational drugs; MYCN; ALK; Ras/MAPK; Clinical trial; Immunotherapy;
مقالات ISI SRCT مشاهده (ترجمه نشده)
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Keywords: SRCT مشاهده; High-risk neuroblastoma; Survival; Progression; MYCN; Multifocal disease
Keywords: SRCT مشاهده; Neuroblastoma; Neuroblastic tumors; MYCN; Immunotherapy; Risk stratification; MIBG;
Keywords: SRCT مشاهده; Neuroblastoma; Risk stratification; MYCN; Segmental chromosome aberrations (SCA); ALK (anaplastic lymphoma kinase); Phox2B; Myeloablative therapy (MAT); Immunotherapy;
Decreased osteoprogenitor proliferation precedes attenuation of cancellous bone formation in ovariectomized rats treated with sclerostin antibody
Keywords: SRCT مشاهده; ANOVA; analysis of variance; BrdU; 5-bromo-2â²-deoxyuridine; CDKN1A; cyclin-dependent kinase inhibitor 1A; CDKN2A; CDKN inhibitor 2A; CE; coefficient of error; CV; coefficient of variation; D; day; E2F1; E2F transcription factor 1; FOXM1; Forkhead box pr
Identification of NMU as a potential gene conferring alectinib resistance in non-small cell lung cancer based on bioinformatics analyses
Keywords: SRCT مشاهده; NSCLC; non-small cell lung cancer; ALK; anaplastic lymphoma kinase; GEO; gene expression omnibus; DEGs; differentially expressed genes; DAVID; database for annotation, visualization and integrated discovery; GO; gene ontology; KEGG; kyoto encyclopedia of
Natural antibody against neuroblastoma of TH-MYCN transgenic mice does not correlate with spontaneous regression
Keywords: SRCT مشاهده; MYCN; Neuroblastoma; Natural antibody;
Promoter-associated proteins of EPAS1 identified by enChIP-MS - A putative role of HDX as a negative regulator
Keywords: SRCT مشاهده; enChIP; HIF-2α; HDX; MYCN; Hypoxia; Neuroblastoma;
CCRK is a novel signalling hub exploitable in cancer immunotherapy
Keywords: SRCT مشاهده; 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous
Identification of a MYCN and Wnt-related VANGL2-ITLN1 fusion gene in neuroblastoma
Keywords: SRCT مشاهده; PCP; Planar cell polarity; LiCl; Lithium chloride; VANGL2; Van Gogh-Like Planar Cell Polarity Protein 2; ITLN1; Intelectin-1; UTR; Untranslated region; ORF; Open reading frame; COSMIC; The catalogue of somatic mutations in cancer; GIANT; The Genome-scale
MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma
Keywords: SRCT مشاهده; MAX; MYCN; Neuroblastoma; MYCN gene amplification;
Detection of oligonucleotides by PNA-peptide conjugates recognizing the biarsenical fluorescein complex FlAsH-EDT2
Keywords: SRCT مشاهده; Peptide nucleic acids; FlAsH-EDT2; Hybridization; Duplex; MYCN; miR 17-5p;
miR-34a sensitizes lung cancer cells to cisplatin via p53/miR-34a/MYCN axis
Keywords: SRCT مشاهده; Cisplatin; miR-34a; NSCLC; MYCN; p53;
Anti-cancer effect of oncolytic adenovirus-armed shRNA targeting MYCN gene on doxorubicin-resistant neuroblastoma cells
Keywords: SRCT مشاهده; Neuroblastoma; MDR; Doxorubicin; MYCN; MRP; Oncolytic adenovirus;
VIP and PACAP analogs regulate therapeutic targets in high-risk neuroblastoma cells
Keywords: SRCT مشاهده; MYCN; ALK; AKT; PKA; Invasion; Differentiation;
Transcript signatures that predict outcome and identify targetable pathways in MYCN-amplified neuroblastoma
Keywords: SRCT مشاهده; Neuroblastoma; Gene signatures; Networks; Biomarkers; Confounding variables; MYCN;
Regulation of Nuclear Hormone Receptors by MYCN-Driven miRNAs Impacts Neural Differentiation and Survival in Neuroblastoma Patients
Keywords: SRCT مشاهده; neuroblastoma; MYCN; miR-17∼92; miRNAs; nuclear hormone receptors; glucocorticoid receptor; MYC inhibitor; differentiation; cancer therapy
NCYM promotes calpain-mediated Myc-nick production in human MYCN-amplified neuroblastoma cells
Keywords: SRCT مشاهده; NCYM; MYCN; Myc-nick; Neuroblastoma; Cell cycle; Calpain;
TWIST1 is a direct transcriptional target of MYCN and MYC in neuroblastoma
Keywords: SRCT مشاهده; MYCN; TWIST1; MYC; Transcriptional regulation neuroblastoma;
MYC impairs resolution of site-specific DNA double-strand breaks repair
Keywords: SRCT مشاهده; Site-specific DSBs; AsiSI restriction enzyme; MYC; MYCN; DSB repair
The Mechanism by Which MYCN Amplification Confers an Enhanced Sensitivity to a PCNA-Derived Cell Permeable Peptide in Neuroblastoma Cells
Keywords: SRCT مشاهده; Proliferating Cell Nuclear Antigen (PCNA); MYC; MYCN; Replication stress; Neuroblastoma; DNA damage response; Chk1
Targeting MYCN IRES in MYCN-amplified neuroblastoma with miR-375 inhibits tumor growth and sensitizes tumor cells to radiation
Keywords: SRCT مشاهده; miR-375; MYCN; IRES; Neuroblastoma; Ionizing irradiation;
Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells
Keywords: SRCT مشاهده; Neuroblastoma; MYCN; PRMT5; Arginine methylation;
Liquid chromatography-tandem mass spectrometric assay for the cyclin-dependent kinase inhibitor AT7519 in mouse plasma
Keywords: SRCT مشاهده; AUC0ââ; area under the plasma concentration-time curve; CDK; cyclin-dependent kinase; Cmax; maximum plasma concentration; EDTA; ethylenediaminetetraacetic acid; i.p.; intraperitoneal; IS; internal standard; MYCN; V-myc myelocytomatosis viral related
The molecular genetic profile of neuroblastoma
Keywords: SRCT مشاهده; ALK; ATRX; expression array; genomic array; miRNA; MYCN; neuroblastoma; 1p; ploidy; 17q
Novel 1p tumour suppressor Dnmt1-associated protein 1 regulates MYCN/ataxia telangiectasia mutated/p53 pathway
Keywords: SRCT مشاهده; DMAP1; ATM; p53; Neuroblastoma; MYCN
Involvement of germline DDX1-MYCN duplication in inherited nephroblastoma
Keywords: SRCT مشاهده; Wilms tumor; Nephroblastomatosis; MYCN; DDX1; 2p24.3 duplication;
Novel anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates modulate the expression of p53-MYCN associated micro RNAs in neuroblastoma cells and cause cell cycle arrest and apoptosis
Keywords: SRCT مشاهده; MYCN; N-MYC; MTT; 3-(4,5-dimethyl thiazol-2-yl)-2,5 diphenyl tetrazolium bromide; RT-PCR; reverse transcription PCR; miRNA; microRNA; p53; miR-34; IMR-32 cells; Neuroblastoma; Apoptosis;
MYC and MYCN amplification can be reliably assessed by aCGH in medulloblastoma
Keywords: SRCT مشاهده; MYC; MYCN; medulloblastoma; aCGH; FISH
ALK amplification and protein expression predict inferior prognosis in neuroblastomas
Keywords: SRCT مشاهده; ALK; MYCN; FISH; IHC; NTs
Constitutional 11q14-q22 chromosome deletion syndrome in a child with neuroblastoma MYCN single copy
Keywords: SRCT مشاهده; Neuroblastoma; 11q syndrome; MYCN; OncogeneARSH, ARSE, ARSD, arilsulphatases genes; aCGH, array comparative genomic hybridization; CR, critical region; DECIPHER, database of chromosomal imbalance and phenotype in humans using ensembl resources; DGV, datab
Myocardial Mycn is essential for mouse ventricular wall morphogenesis
Keywords: SRCT مشاهده; MYCN; Myocardial wall development; Trabeculation; Cardiogenesis; Heart development
A de novo 4.4-Mb microdeletion in 2p24.3 â p24.2 in a girl with bilateral hearing impairment, microcephaly, digit abnormalities and Feingold syndrome
Keywords: SRCT مشاهده; 2p24.3 Deletion; Cochlea; Deafness; Feingold syndrome; Hearing impairment; MYCN; N-myc;
Towards a turning point of neuroblastoma therapy
Keywords: SRCT مشاهده; Neuroblastoma; MYCN; ALK; aCGH; High risk neuroblastoma; Personalized therapy
DNA demethylation increases sensitivity of neuroblastoma cells to chemotherapeutic drugs
Keywords: SRCT مشاهده; Neuroblastoma; Chemotherapeutic drugs; MYCN; DNA methylation; 5-Aza-2′-deoxycytidine
Neonatal neuroblastoma
Keywords: SRCT مشاهده; Genetics; MYCN; Neonate; Neuroblastoma; Screening; Spinal cord compression
CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells
Keywords: SRCT مشاهده; Rett's syndrome; CDKL5; MYCN; Neurogenesis; Differentiation;
The p53 Codon 72 Pro/Pro Genotype Identifies Poor-Prognosis Neuroblastoma Patients: Correlation with Reduced Apoptosis and Enhanced Senescence by the p53-72P Isoform
Keywords: SRCT مشاهده; 4-HT; 4-hydroxy-tamoxifen; ER; estrogen receptor; IR; ionizing radiation; MDM2; murine double minute; MYCN; v-myc myelocytomatosis viral-related oncogene neuroblastoma derived; NB; neuroblastoma; SNP; single nucleotide polymorphism;
Stable knockdown of MYCN by lentivirus-based RNAi inhibits human neuroblastoma cells growth in vitro and in vivo
Keywords: SRCT مشاهده; MYCN; RNAi/shRNA; Lentivirus; Neuroblastoma;
MicroRNA and DNA methylation alterations mediating retinoic acid induced neuroblastoma cell differentiation
Keywords: SRCT مشاهده; ATRA; MYCN; Neuroblastoma; microRNA; NCOR2; Differentiation; NOS1; DNA methylation
Array Comparative Genomic Hybridization Analysis Identifies Recurrent Gain of Chromosome 2p25.3 Involving the ACP1 and MYCN Genes in Chronic Lymphocytic Leukemia
Keywords: SRCT مشاهده; ACP1; Chromosome 2p; CLL; MYCN
Inhibition of mir-21, which is up-regulated during MYCN knockdown-mediated differentiation, does not prevent differentiation of neuroblastoma cells
Keywords: SRCT مشاهده; Neuroblastoma; MYCN; microRNA; Neuronal differentiation; Mir-21MNA, MYCN-amplified; TPA, 12-O-tetradecanoyl phorbol 13-acetate; RA, retinoic acid; BDNF, brain-derived neurotrophic factor; bFGF, basic fibroblast growth factor; IGF, insulin-like growth fact
The MYCN oncogene and differentiation in neuroblastoma
Keywords: SRCT مشاهده; MYCN; p53; p73; Differentiation; Retinoic acid; Mouse models; Neuroblastoma; Trk receptors; miRNA
Genetically engineered murine models – Contribution to our understanding of the genetics, molecular pathology and therapeutic targeting of neuroblastoma
Keywords: SRCT مشاهده; MYCN; Neuroblastoma; Mouse models
Gain of the short arm of chromosome 2 (2p) is a frequent recurring chromosome aberration in untreated chronic lymphocytic leukemia (CLL) at advanced stages
Keywords: SRCT مشاهده; 2p gain; CLL; MYCN; REL;
Expression and functional role of inhibitor-of-apoptosis protein livin (BIRC7) in neuroblastoma
Keywords: SRCT مشاهده; Neuroblastoma; Livin; MYCN; Drug resistance; Gene silencing; Apoptosis
Aberrant copy numbers of ALK gene is a frequent genetic alteration in neuroblastomas
Keywords: SRCT مشاهده; Neuroblastoma; ALK; MYCN; Copy number alterations
Positive auto-regulation of MYCN in human neuroblastoma
Keywords: SRCT مشاهده; MYCN; Neuroblastoma; Neuronal differentiation; All-trans-retinoic acid (ATRA); Positive auto-regulation
Regulation of BIRC5 and its isoform BIRC5-2B in neuroblastoma
Keywords: SRCT مشاهده; BIRC5; BIRC5-2B; MYCN; E2F1; Neuroblastoma
HIF-1α induces MXI1 by alternate promoter usage in human neuroblastoma cells
Keywords: SRCT مشاهده; MXI1; Hypoxia; HIF-1; Hypoxia responsive elements (HRE); Neuroblastoma; MYCN