Keywords: Nothobranchius; Guentheri; Killifish; Fertility; Fecundity; SirT1; NAMPT; Resveratrol;
مقالات ISI (ترجمه نشده)
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Keywords: Nicotinamide adenine dinucleotide; Nicotinamide phosphoribosyl transferase; High fat feeding; Mitochondrial gene expression; Insulin sensitivity; Exercise; CD; chow diet; HFD; 45% high fat diet; LFD; 10% low fat diet; Mck; muscle creatine kinase; NAD+; ni
Keywords: daily oscillation; NAD; Nampt; Npt2a; Npt2c; phosphate;
Keywords: Sirt1; Sirtuin 1; SREBPs; Sterol regulatory element binding proteins; AMPK; AMP-activated protein kinase; ACC; Acetyl-CoA carboxylase; Fas; Fatty acid synthase; Nampt; Nicotinamide phosphoribosyltransferase; LKB1; Liver kinase B1; ER; Endoplasmic reticulu
Keywords: eNAMPT; extracellular nicotinamide phosphoribosyltransferase; FGF-23; fibroblast growth factor-23; iNAMPT; intracellular nicotinamide phosphoribosyltransferase; NAD; nicotinamide adenine dinucleotide; NAM; nicotinamide; NAMPT; nicotinamide phosphoribosylt
Dietary tea polyphenols ameliorate metabolic syndrome and memory impairment via circadian clock related mechanisms
Keywords: TP; tea polyphenols; DD; constant darkness; SCN; suprachiasmatic nucleus; LD; light-dark; CLOCK; circadian locomotor output cycles kaput; BMAL1; brain and muscle arnt-like protein-1; CRY; cryptochromes; REV-ERB; -; RORs; RAR-related orphan receptors; PE
Keywords: CLOCK; circadian locomotor output cycles kaput; BMAL; brain and muscle aryl hydrocarbon receptor nuclear translocator (ARNT)-like; SNC; suprachiasmic nuclei; PER; period; CRY; cryptochrome; ROR-alpha; RAR-related orphan receptor alpha; NAM; nicotinamide;
Keywords: BAK; BCL-2 antagonist killer; BAX; BCL-2 associated X protein; CDK1; cyclin dependent kinase 1; CLDN-6; claudin-6; CM; cardiomyocyte; CPE; Clostridium perfringens endotoxin; GPX2; glutathione peroxidase-2; GSH; glutathione; GSR; glutathione reductase; GSS
Keywords: Pancreatic cancer; Aerobic glycolysis; NAD; Nampt; miR-206
Keywords: CNS; central nervous system; INS-1; insulin secreting β-cell line originated from a rat insulinoma; GK rat; Goto-Kakizaki rat; NOD mouse; non-obese diabetic mouse; TKP; tryptophan/kynurenine pathway; Trp; tryptophan; KYN; kynurenine; 3HK; 3-OH-kynureni
Keywords: ACSS; acetyl-CoA synthetase; ADI; arginine deiminase; AML; acute myeloid leukaemia; AMPK; AMP-activated protein kinase; ALL; acute lymphoblastic leukaemia; ASS; argininosuccinate synthase; BCAAs; branched-chain amino acids; BPTES; bis-2-(5-phenylacetamido
Keywords: Visfatin; Diabetes; Testis; Testosterone; Rat; DM; Diabetes mellitus; MZUAEC; Mizoram University Animal Ethics Committee; NAD; nicotinamide adenine dinucleotide; NAMPT; nicotinamide phosphoribosyltransferase; NMN; nicotinamide mononucleotide; PBS; phospha
Keywords: PH; partial hepatectomy; I/R; ischemia-reperfusion; Nampt; nicotinamide phosphoribosyltransferase; NAD; nicotinamide adenine dinucleotide; TNF; tumor necrosis factor; IL; interleukin; Ob; obese; Ln; lean; BrdU; bromo-deoxyuridine; AST; aspartate aminotran
Keywords: Asthma; inflammatory phenotypes; gene expression; induced sputum; neutrophils; eosinophils; ACQ; Asthma Control Questionnaire; ALPL; Alkaline phosphatase, tissue-nonspecific isozyme; AUC; Area under the curve; BIRC3; Baculoviral IAP repeat containing 3; B
Keywords: CRC; colorectal cancer; IACR; International Agency for Cancer Research; AMPK; adenosin monophosphate-activated protein kinase; mTOR; mammalian target of the rapamycin; Nampt; nicotinamide phosphoribosyltransferase; PBEF1; pre-B cell-colony enhancing facto
Fragment-based discovery of a potent NAMPT inhibitor
Keywords: NMR; Fragment-based; FBDD; FBLD; NAMPT;
The role of SIRT1 in diabetic retinopathy
Keywords: SIR2; Silent Information Regulator2; HDACs; histone deacetylaser; NAD+; nicotinamide adenine dinucleotide; DM; diabetes mellitus); AGEs; advanced glycation end products; AMPK; adenosine monophosphate-activated protein kinas; TGFβ1; transforming growth fa
Structure based design of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors from a phenotypic screen
Keywords: NAMPT; In silico screen; Structure based drug design; Cyclopropane; Nicotinamide phosphoribosyltransferase;
Cyanidin-3-O-β-glucoside regulates the activation and the secretion of adipokines from brown adipose tissue and alleviates diet induced fatty liver
Keywords: Cy-3-G; cyanidin-3-O-β-glucoside; BAT; brown adipose tissue; NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; UCP1; uncoupling protein 1; NGF; nerve growth factor; VEGFA; vascular endothelial growth factor A; PET; positron e
Identification and expression patterns of adipokine genes during adipocyte differentiation in the Tibetan goat (Capra hircus)
Keywords: FGF21; fibroblast growth factor 21; APLN; apelin; RETN; resistin; NAMPT; visfatin; RELM; resistin-like molecule; NAD; nicotinamide adenine dinucleotide; ORO; Oil red O; TG; triglyceride; PPARγ; peroxisome proliferator-activated receptor γ; Goat; Adipoki
Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1α/mitochondrial biosynthesis pathway
Keywords: ADH; alcohol dehydrogenase; ALD; Alcoholic liver disease; ALDH; aldehyde dehydrogenase; CPT-1α; carnitine palmitoyl transterase-1α; CR; calorie restriction; CS; citrate synthase; CYP2E1; cytochrome P450 2E1; FASN; fatty acid synthase; NAD+; nicotinamide
NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity
Keywords: Adipose metabolism; Obesity; NAMPT; NAD+ synthesis; Energy homeostasis; Adipose plasticity; Glucose homeostasis; AUC; Area under curve; Bmp8b; Bone morphogenetic factor 8b; eWAT; epididymal white adipose tissue; FANKO; Fat-specific Nampt knockouts; Fgf21;
An in vitro comparative study of the antioxidant activity and SIRT1 modulation of natural compounds
Keywords: AMPK; adenosine monophosphate-activated protein kinase; APAB; 2,2â²-azo-bisamidinopropane; BSA; bovine serum albumin; CCL4; carbon tetrachloride; DMEM; Dulbecco's modified eagle's medium; DMSO; dimethyl sulfoxide; DTPA; diethylenetriaminepentaacetic acid
GLUT1 protects prostate cancer cells from glucose deprivation-induced oxidative stress
Keywords: 2DG; 2-deoxyglcuose; AMPK; AMPK-activated protein kinase; AR; Androgen Receptor; CAT; Catalase; DHA; Dehydroascorbic Acid; G6PG; Glucose-6-phosphate dehydrogenase; GPX; Glutathione peroxidase; GSH; Reduced glutathione; GSSG; Oxidized glutathione; HTLV; Hu
NAD metabolism: Implications in aging and longevity
Keywords: NAD; Aging; Aging-associated disease; Longevity; Nampt; Nmnat;
Selective Cytotoxicity of the NAMPT Inhibitor FK866 Toward Gastric Cancer Cells With Markers of the Epithelial-Mesenchymal Transition, Due to Loss of NAPRT
Keywords: Stomach Cancer; Drug Screen; Partial Epithelial-to-Mesenchymal Transition; Synthetic Lethal; ACRG; Asian Cancer Research Group; EMT; epithelial-to-mesenchymal transition; NAD+; nicotinamide adenine dinucleotide; NAMPT; nicotinamide phosphoribosyltransfera
Overexpression of miR-182 inhibits ossification of ligamentum flavum cells by targeting NAMPT
Keywords: Ossification; Ligamentum flavum; NAMPT; miR-182; RUNX2; OCN; OPN;
Down-regulation of NAMPT expression by mir-206 reduces cell survival of breast cancer cells
Keywords: NAD; nicotinamide adenine dinucleotide; NAMPT; nicotinamide phosphoribosyltransferase; NA; nicotinic acid; NMN; nicotinamide mononucleotide; NMNAT; nicotinamide mononucleotide adenylyltransferases; PBEF1; pre-B cell colony-enhancing factor 1; BC; breast c
NAMPT: A pleiotropic modulator of monocytes and macrophages
Keywords: NAMPT; Cytokine; Monocytes; Macrophages;
Association of genetic variants in RETN, NAMPT and ADIPOQ gene with glycemic, metabolic traits and diabetes risk in a Chinese population
Keywords: T2DM; type 2 diabetes mellitus; RETN; resistin; NAMPT; visfatin; ADIPOQ; adiponectin; SNP; single nucleotide polymorphism; GWAS; genome-wide association study; WHO; World Health Organization; FBG; fasting blood glucose; GI; glycemic index; HBCI; HOMAB-cel
The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance
Keywords: ABCB1; ATP-binding cassette sub-family B member 1; AML; acute myeloid leukaemia; AMPK; adenosine monophosphate-activated protein kinase; ATM; Ataxia-telangiectasia mutated; AURKA; aurora kinase A; BER; base excision repair; Bim; B-cell lymphoma 2 interact
Autophagy in ischemic stroke
Keywords: 3-MA; 3-methyladenine; Aβ; amyloid β; AIF; apoptosis-inducing factor; Akt; protein kinase B; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; Atg; autophagy-related genes; ATP; adenosine 5â²-triphosphate; BBB; blood-brain ba
Identification of novel resistance mechanisms to NAMPT inhibition via the de novo NAD+ biosynthesis pathway and NAMPT mutation
Keywords: QPRT; NAMPT; GMX1778; A-1293201; NAD+;
Regulation of Nampt expression by transcriptional coactivator NCOA6 in pancreatic β-cells
Keywords: NCOA6; Nampt; SREBP-1c; Insulin secretion; Glucose tolerance;
Nicotinamide phosphoribosyltransferase (Nampt) may serve as the marker for osteoblast differentiation of bone marrow-derived mesenchymal stem cells
Keywords: Nampt; nicotinamide phosphoribosyltransferase; MSCs; mesenchymal stem cells; NAD; nicotinamide adenine dinucleotide; BM-MSCs; bone marrow-derived mesenchymal stem cells; ROS; reactive oxygen species; PARPs; poly ADP-ribose polymerases; NMN; nicotinamide m
Cyanidin-3-O-β-glucoside protects against liver fibrosis induced by alcohol via regulating energy homeostasis and AMPK/autophagy signaling pathway
Keywords: Cy-3-G; cyanidin-3-O-β-glucoside; NAD+; nicotinamide adenine dinucleotide; NMN; nicotinamide mononucleotide; ATP; adenosine triphosphate; NAMPT; nicotinamide phosphoribosyltransferase; SITR1; sirtuin1; SREBP-1c; sterol regulatory element binding protein-
EGCG ameliorates diet-induced metabolic syndrome associating with the circadian clock
Keywords: EGCG; Epigallocatechin gallate; CLOCK; Circadian locomotor output cycles kaput; BMAL1; Brain and muscle arnt-like protein-1; CRY; Cryptochromes; PER; Period; SIRT1; Sirtuin 1; PGC1α; Peroxisome proliferator-activated receptor coactivator 1-α; IR; Insuli
The NAMPT/E2F2/SIRT1 axis promotes proliferation and inhibits p53-dependent apoptosis in human melanoma cells
Keywords: Melanoma; NAMPT; SIRT1; Apoptosis; E2F2;
Improved synthesis of MC4-PPEA and the biological evaluation of its hydroxymethyl derivative
Keywords: Nampt; nicotinamide phosphoribosyltransferase; MC4-PPEA; 1-(4â²-(trans-3â³-(3â´-pyridyl) acrylamide)butyl)-1,7-dicarba-closo-dodecaborane; BNCT; boron neutron capture therapy; BOP; benzotriazole-1-yl-oxy-tris-(dimethylamino)-phosphonium hexafluorophosp
NAMPT regulates senescence, proliferation, and migration of endothelial progenitor cells through the SIRT1 AS lncRNA/miR-22/SIRT1 pathway
Keywords: NAMPT; SIRT1; lncRNA; miR-22; Endothelial progenitor cells; Senescence;
Application of virtual screening to the discovery of novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with potential for the treatment of cancer and axonopathies
Keywords: NAMPT; Virtual screening; Axon degeneration; Molecular docking; Similarity searching;
NAMPT-Mediated NAD+ Biosynthesis in Adipocytes Regulates Adipose Tissue Function and Multi-organ Insulin Sensitivity in Mice
Keywords: adipocyte; NAMPT; NAD+; insulin resistance; obesity; PPARγ
Research ArticleNMNAT3 is involved in the protective effect of SIRT3 in Ang II-induced cardiac hypertrophy
Keywords: SIRT; sirtuin; NMNAT; nicotinamide mononucleotide adenylyltransferase; NAMPT; nicotinamide phosphoribosyltransferase; NAD; nicotinamide adenine dinucleotide; Ang II; angiotensin II; ANF; atrial natriuretic factor; BNP; brain natriuretic polypeptide; NRCMs
AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions
Keywords: ACAT1; acetoacetyl-CoA thiolase; ACC; acetyl-CoA carboxylase; AICAR; 5-aminoimidazole-4-carboxamide ribonucleoside; AMPK; AMP-activated protein kinase; ATAC; Ada-two-A-containing; BET; bromodomains and extra-terminal motif; BMAL1; PAS domain-containing pr
A conjugated fatty acid present at high levels in bitter melon seed favorably affects lipid metabolism in hepatocytes by increasing NAD+/NADH ratio and activating PPARα, AMPK and SIRT1 signaling pathway
Keywords: ACC; acetyl-CoA carboxylase; ACOX; acyl-CoA oxidase; AMPK; AMP-activated protein kinase; BMSO; bitter melon seed oil; c9,t11-CLA; cis-9, trans-11 isomer of conjugated linoleic acid; α-ESA; α-eleostearic acid; FASN; fatty acid synthase; FOXO1; forkhead b
Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment
Keywords: APRIL; a proliferation-inducing ligand; ATM; ataxia telangiectasia mutated; BAFF; B-cell activating factor; BAFFR; BAFF receptor; BAG6; BCL2-associated athanogene 6; BCMA; B-cell maturation antigen; BCL2; B-cell lymphoma 2; BCR; B cell receptor; bFGF; bas
Genomics of human fatty liver disease reveal mechanistically linked lipid droplet-associated gene regulations in bland steatosis and nonalcoholic steatohepatitis
Keywords: ACACB; acetyl-CoA carboxylase beta acetyl-CoA carboxylase beta; ACAT1; acetyl-CoA acetyltransferase 1; ACLY; ATP citrate lyase; AMPK; 5â²AMP-activated protein kinase; ASCL1; acyl-CoA synthetase long-chain family member 1; ACSL4; acyl CoA synthetases long
Increased expression of NAMPT in PBMC from patients with acute coronary syndrome and in inflammatory M1 macrophages
Keywords: Macrophage polarization; Atherosclerosis; NAMPT; Acute coronary syndrome; Inflammation;
Hepatic NAD salvage pathway is enhanced in mice on a high-fat diet
Keywords: NAMPT; NAD; Fatty liver; High-fat diet; Mouse;
Nicotinamide Phosphoribosyltransferase/Pre–B-Cell Colony Enhancing Factor/Visfatin Plasma Levels and Clinical Outcome in Patients With Dilated Cardiomyopathy
Keywords: Nampt; heart failure; cardiomyopathy