دانلود مقالات ISI درباره Nampt + ترجمه فارسی

NAMPT inhibitor and metabolite protect mouse brain from cryoinjury through distinct mechanisms

Keywords: ANOVA; analysis of variance; NAD; nicotinamide adenine dinucleotide; NAMPT; nicotinamide phosphoribosyltransferase; NMN; nicotinamide mononucleotide; NAMPT; FK866; NMN; NAD; cryoinjury; brain injury;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

1-Methylnicotinamide ameliorates lipotoxicity-induced oxidative stress and cell death in kidney proximal tubular cells

Keywords: BSA; bovine serum albumin; Enpp3; ectonucleotide pyrophosphatase/phosphodiesterase 3; ESRD; end stage renal disease; FFA; free fatty acid; 4-HNE; 4-hydroxy-2-nonenal; HO-1; heme oxigenase-1; MCP-1; monocyte chemoattractant protein-1; 1-MNA; 1-methylnicoti

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Troxerutin protects against 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47)-induced liver inflammation by attenuating oxidative stress-mediated NAD+-depletion

Keywords: Polybrominated diphenyl ethers; Oxidative stress; NAD+; Inflammation; Troxerutin; AC-H3K9; acetyl-histone H3 (Lys9); AC-p65 (K310); acetyl-NF-κB p65 (Lys310); ALT; alanine aminotransferase; BDE-47; 2,2′,4,4′-tetrabromodiphenyl ether; CYP; cytochrome

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Sirtuins in vascular diseases: Emerging roles and therapeutic potential

Keywords: ACE; angiotensin converting enzyme; AICAR; 5-amino-4-imidazolecarboxamide riboside; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; ApoE; apolipoprotein E; AT1R; angiotensin II type 1 receptor; ATM; ataxia telangiectasia mutated; ATP; adenosin

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility

Keywords: Nicotinamide phosphoribosyltransferase; NAMPT; Cytochrome P450 time-dependent inhibition; CYP TDI; Aqueous solubility; Tumor metabolism

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Dedifferentiation of cancer cells following recovery from a potentially lethal damage is mediated by H2S-Nampt

Keywords: CBS; Cyctathionine beta synthase; CTH; Cystathionase; MST; 3-mercaptopyruvate sulfurtransferase; PLDR; potentially lethal damage recovery; CHH; O-(carboxymethyl) hydroxylamine hemihydrochloride, inhibitor of Cyctathionine beta synthase; PAG; DL-propargylg

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Pyrroloquinoline quinone increases the expression and activity of Sirt1 and -3 genes in HepG2 cells

Keywords: Sirtuins; Pyrroloquinoline quinone; Metabolic syndrome; Mitochondria; Aging; Mitochondrial biogenesis regulators; CR; caloric restriction; mRNA; messenger RNA; NAMPT; nicotinamide phosphoribosyltransferase; NRF-1; nuclear respiratory factor 1; NRF-2; nucl

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2015 سفارش ترجمه

MYC and metabolism on the path to cancer

Keywords: 2-DG; 2-deoxyglucose; 4E-BP; eIF4E-binding protein; 5,10-methylene THF; 5,10-methylenetetrahydrofolate; ACC; acetyl-CoA carboxylase; ACLY; ATP-citrate lyase; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; ChIP-seq; chromatin immunoprecip

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) as a therapeutic strategy in cancer

Keywords: Tumor metabolism; NAD; NAMPT; NAPRT1; Targeted agents; ATP; adenosine triphosphate; NA; nicotinic acid; NAD; nicotinamide adenine dinucleotide; (NAM); nicotinamide; NAMN; nicotinic acid mononucleotide; NAMPT; nicotinamide phosphoribosyltransferase; NAPRT1

دانلود رایگان متن کامل مقاله ISI 88 صفحه سال انتشار : 2015 سفارش ترجمه

Mussel oligopeptides protect human fibroblasts from hydrogen peroxide (H2O2)-induced premature senescence

Keywords: CK; control experiment; DMSO; dimethylsulfoxide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide; NAMPT; nicotinamide phosphoribosyltransferase; Prx1; peroxiredoxin 1; PSC; premature senescence control; SA-β-gal; senescence-associated

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors

Keywords: Nicotinamide phosphoribosyltransferase; Nampt; cyanoguanidine; X-ray crystal structure;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Fragment-based design of 3-aminopyridine-derived amides as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)

Keywords: Nicotinamide phosphoribosyltransferase; NAMPT; Fragment-based design; Structure-based design; X-ray crystal structure; Surface plasmon resonance;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Nicotinamide phosphoribosyltransferase can affect metastatic activity and cell adhesive functions by regulating integrins in breast cancer

Keywords: AMP; adenosine monophosphate; ATP; adenosine triphosphate; BRCA1; breast cancer 1; BRCA2; breast cancer 2; eNAMPT; extracellular nicotinamide phosphoribosyltransferase; ERK; extracellular signal-regulated kinases; iNAMPT; intracellular nicotinamide phosph

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Role of SIRT1 and AMPK in mesenchymal stem cells differentiation

Keywords: MSCs; mesenchymal stem cells; SIRT1; silent mating type information regulation 2 homolog 1; AMPK; AMP-activated protein kinase; ROS; reactive oxygen species; CR; calorie restriction; PPARγ; peroxisome proliferator-activated receptor gamma; C/EBP; CCAAT/e

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Liquid fructose downregulates Sirt1 expression and activity and impairs the oxidation of fatty acids in rat and human liver cells

Keywords: ACO; acyl-CoA oxydase; AMPK; AMP-activated protein kinase; APRT; adenosyl phosphoribosyl transferase); ACC; acetyl-CoA carboxylase); ChREBP; carbohydrate response element binding protein; CYP4A1; cytochrome P450 4A1; FAS; fatty acid synthase; Foxa2; forkh

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Endogenous NAMPT dampens chemokine expression and apoptotic responses in stressed tubular cells

Keywords: Diabetes; NAMPT; Apoptosis; Inflammation; Kidney;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Visfatin contributes to the differentiation of monocytes into macrophages through the differential regulation of inflammatory cytokines in THP-1 cells

Keywords: DeM; differentiated macrophages; DiM; differentiating macrophages; ERK; extracellular signal-regulated kinase; FACS; fluorescence-activated cell sorter; FBS; fetal bovine serum; HRP; horseradish peroxidase; iNOS; inducible nitric oxide synthase; IL-1Ra; I

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Transcriptomics profiling and steroid production in mummichog (Fundulus heteroclitus) testes after treatment with 5α-dihydrotestosterone

Keywords: 11KT; 11-ketotestosterone; ABCC2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; ABCC3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; ABCG8; ATP-binding cassette, sub-family G (WHITE), member 8; ACY1; aminoacylase 1; ADAR; adenosine d

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

PARP and other prospective targets for poisoning cancer cell metabolism

Keywords: ATP; adenosine 5′-triphosphate; 3-BrPA; 3-bromopyruvate; EGFR; epidermal growth factor receptor; FDA; food and drug administration; GSH; glutathione; GSSG; oxidized GSH; GST; glutathione S-transferase; HDAC; histone deacetylase; HIF1; hypoxia inducible

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2014 سفارش ترجمه

Light-dark condition regulates sirtuin mRNA levels in the retina

Keywords: NAD; nicotinamide adenine dinucleotide; Nampt; nicotinamide phosphoribosyltransferase; PGC1α; peroxisome proliferator-activated receptor gamma coactivator; Tfam; transcription factor A, mitochondrial; LD condition; light/dark condition; DD condition; con

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Down-regulation of NAMPT expression by miR-182 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation

Keywords: HIV-1; human immunodeficiency virus type 1; LTR; long terminal repeats; PTM; post-translational modification; SIRT1; sirtuin 1; NAD+; nicotinamide adenine dinucleotide; NAMPT; nicotinamide phosphoribosyltransferase; DMEM; Dulbecco's modified Eagle's mediu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties

Keywords: Nicotinamide phosphoribosyltransferase; NAMPT; X-ray crystal structure; Cytochrome P450; CYP2C9;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders

Keywords: AGRP; agouti-related protein; AMPK; AMP-activated protein kinase; AP-1; activator protein-1; BCL10; B-cell lymphoma/leukemia-10; CIITA; class II, major histocompatibility complex, transactivator; DHA; docosahexaenoic acid; E2F1; transcription factor E2F1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Transcriptomic profiling of progesterone in the male fathead minnow (Pimephales promelas) testis

Keywords: 11-KT; 11-ketotestosterone; AKT1; RAC-α serine/threonine-protein kinase; APOE; apolipoprotein E; APP; amyloid β (A4) precursor protein; AR; androgen receptor; BCL2L1; BCL2-like 1; BCL6; B-cell CLL/lymphoma 6; BMP2; bone morphogenetic protein 2; BMP4; bo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Redox-regulating sirtuins in aging, caloric restriction, and exercise

Keywords: 8-oxoG, 8-oxo-7; 8-dihydroguanine; APE1; apurinic/apyrimidinic endonuclease 1; BER; DNA base excision repair; CR; caloric restriction; DSB; DNA double-strand break; FOXO; forkhead homeobox type O protein; eIF2α; eukaryotic initiation factor 2α; eNOS; en

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)

Keywords: Nicotinamide phosphoribosyltransferase; NAMPT; Aqueous solubility; X-ray crystal structure; Tumor metabolism;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

The sources of salidroside and its targeting for multiple chronic diseases

Keywords: 6-OHDA; 6-hydroxydopamine; Aβ; β-amyloid protein; MPTP; 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine; MPP+; N-methyl-4-phenylpyridine; AD; Alzheimer's disease; PD; Parkinson's disease; STZ; streptozotocin; PI3K; phosphatidylinositol 3-kinase; ROS; react

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2020 سفارش ترجمه

Association of genetic variability in selected regions in visfatin (NAMPT) gene with anthropometric parameters and dietary composition in obese and non-obese Central-European population

Keywords: Visfatin; NAMPT; SNP; Dietary composition; Anthropometric parameters; Extreme obesity

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Supplementation of Nicotinic Acid with NAMPT Inhibitors Results in Loss of In Vivo Efficacy in NAPRT1-Deficient Tumor Models

Keywords: NA; nicotinic acid; NAD; nicotinamide adenine dinucleotide; NAM; nicotinamide; NAMPT; nicotinamide phosphoribosyltransferase; NAPRT1; nicotinic acid phosphoribosyltransferase domain containing 1;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2013 سفارش ترجمه

Visfatin and its role in obesity development

Keywords: Visfatin; NAMPT; Adipocytokines; Lipid metabolism; Obesity

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

The role of SIRT3 in mitochondrial homeostasis and cardiac adaptation to hypertrophy and aging

Keywords: ALDH2; aldehyde dehydrogenase 2; AMPK; adenosine monophosphate kinase; CREB; cyclic AMP response element binding protein; GNAT; Gcn5-related N-acetyltransferase; HAT; histone acetyltransferase; HDAC; histone deacetylase; LCAD; long chain acetyl-CoA dehydr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

NAMPT pathway is involved in the FOXO3a-mediated regulation of GADD45A expression

Keywords: FOXO3a; Acetylation; NAMPT; Sirtuins (SIRTs); FK866

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Nicotinamide Phosphoribosyltransferase: A Potent Therapeutic Target in Non-small Cell Lung Cancer with Epidermal Growth Factor Receptor-Gene Mutation

Keywords: Non-small cell lung cancer; EGFR; NAMPT; FK866; ATP

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

The role of SirT1 in muscle mitochondrial turnover

Keywords: SirT1; AMPK; Nampt; Mitochondrial biogenesis; Autophagy; Circadian rhythm;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Cardiovascular effects and molecular targets of resveratrol

Keywords: 4-HNE; 4-hydroxy-2-nonenal; ADMA; asymmetric dimethylarginine; AMPK; AMP-activated protein kinase; ApoE; apolipoprotein E; ARE; antioxidant response element; BH4; tetrahydrobiopterin; Cav-1; caveolin-1; COX-1; cyclooxygenase 1; CREB; cAMP response element

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis

Keywords: Metabolic syndrome; Berberine; Mitochondria; SIRT1; AMPK; NAMPT

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Dissecting systemic control of metabolism and aging in the NAD World: The importance of SIRT1 and NAMPT-mediated NAD biosynthesis

Keywords: Aging; Longevity; SIRT1; NAMPT; NAD biosynthesis; NAD World

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

A fluorometric assay for high-throughput screening targeting nicotinamide phosphoribosyltransferase

Keywords: Nampt; NAD; NMN; Enzyme activity assay; High-throughput screening

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Muscle type-specific responses to NAD+ salvage biosynthesis promote muscle function in Caenorhabditis elegans

Keywords: Nicotinic acid; Niacin; NAMPT; Visfatin; Vitamin B3;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

A heuristic model for paradoxical effects of biotin starvation on carbon metabolism genes in the presence of abundant glucose

Keywords: Biotin; Yeast; Saccharomyces cerevisiae; Nematode; Caenorhabditis elegans; Rat; Rattus norvegicus; Glucose; Fatty acid; β-oxidation; Gluconeogenesis; Glycolysis; Fermentation; ATP; AMPK; Snf1; Microarrays; SREBP-1c; ChREBP; NAMPT; PGC-1α; mTORC1; Adr1; Ca

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Association of increased Visfatin/PBEF/NAMPT circulating concentrations and gene expression levels in peripheral blood cells with lipid metabolism and fatty liver in human morbid obesity

Keywords: Fatty liver disease; Gene expression; Inflammation; Lipid metabolism; NAMPT; Obesity; Peripheral blood cells

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes

Keywords: NAMPT; Nicotinamide phosphoribosyltransferase; Hepatocytes; NMN biosynthesis; PBEF; Visfatin; ABC; ATP binding cassette transporter; ATP; adenosine triphosphate; BSA; bovine serum albumin; cpm; counts per minute; ER; endoplasmic reticulum; FBS; fetal bovi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

A possibility of nutriceuticals as an anti-aging intervention: Activation of sirtuins by promoting mammalian NAD biosynthesis

Keywords: NAD-dependent deacetylases; Sirtuins; SIRT1; NAD biosynthesis; Nicotinamide phosphoribosyltransferase; NAMPT; Anti-aging medicine; Pharmaceuticals; Nutriceuticals; Aging; Metabolism

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Pre-B cell colony enhancing factor/NAMPT/visfatin and its role in inflammation-related bone disease

Keywords: PBEF; NAMPT; Visfatin; Osteoclast; Inflammatory bowel disease; Bone mineral density;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

“Clocks” in the NAD World: NAD as a metabolic oscillator for the regulation of metabolism and aging

Keywords: SIRT1; NAMPT; NAD biosynthesis; Circadian rhythm; CLOCK; BMAL1; NAD; Metabolic oscillator; NAD World; Metabolism; Aging; Aging clock

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Plasma and myocardial visfatin expression changes are associated with therapeutic hypothermia protection during murine hemorrhagic shock/resuscitation

Keywords: Inflammation; Temperature; Resuscitation; Cytokine; Visfatin; Pre-B-cell colony-enhancing factor; Nampt; Interleukin-6; Tumor necrosis factor-alpha; Keratinocyte-derived chemokine; CXCL1; Hemorrhagic shock

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Novel Danshen methoxybenzo[b]furan derivative antagonizing adipogenic differentiation and production of inflammatory adipokines

Keywords: aP2; adipocyte fatty acid-binding protein-4; C/EBPα; CCAAT/enhancer-binding protein α; DMEM; Dulbecco's modified Eagle medium; FBS; fetal bovine serum; MTT; 3-(4, 5-dimetylthiazol-yl)-diphenyl tetrazolium bromide; Nampt; nicotinamide phosphoribosyl-tran

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

From heterochromatin islands to the NAD World: A hierarchical view of aging through the functions of mammalian Sirt1 and systemic NAD biosynthesis

Keywords: Aging; Metabolism; Sirt1; Nampt; Systemic NAD biosynthesis; Heterochromatin island; NAD World; Pancreatic beta cell; Neuron; Robustness; Frailty; System dynamics

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Nampt/PBEF/Visfatin: A regulator of mammalian health and longevity?

Keywords: Caloric restriction; Dietary restriction; Aging; PBEF; Nampt; Lifespan; Sirtuin; Sir2; NAD+ salvage pathway; Nmnat; Longevity; Nicotinamide; SIRT1; Chromatin; DNA stability; CR; DR

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Toward a unified theory of caloric restriction and longevity regulation

Keywords: Histone deacetylase; SIR2; PBEF; NAMPT; Visfatin; Aging; Sirtuin; HDAC; Nicotinamide; Resveratrol; Xenohormesis;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2005 سفارش ترجمه