دانلود مقالات ISI درباره Ncor + ترجمه فارسی

مسیرهای آلوستریک در گیرنده های هسته ای - اهداف بالقوه برای طراحی دارو

Allosteric pathways in nuclear receptors - Potential targets for drug design

Keywords: 9c; 9-cis retinoic acid; AF1 (or 2); activation function 1(or 2); AR; androgen receptor; CAR; constitutive androstane receptor; ChIP; chromatin immunoprecipitation; DBD; DNA binding domain; ER; estrogen receptor; ERE; estrogen response elements; GR; gluco

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

هورمون تیروئید در تنظیم کارسینوم هپاتوسلولار و محیط میکرو آن

Thyroid hormone in the regulation of hepatocellular carcinoma and its microenvironment

Keywords: Thyroid hormone; Liver cancer; Tumor microenvironment; Liver fibrogenesis; ALT; alanine amino transferase; BBC; basal cell carcinoma; CCL4; carbontetrachloride; CD; choline-deficient; CDK2; cyclin-dependent kinase; CSC; cancer stem cell; DKK; dickkopf Wnt

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

ابزارهای اپیزیونیک (نویسندگان، خوانندگان و پاک کننده ها) و پیامدهای آنها در درمان سرطان

Epigenetic tools (The Writers, The Readers and The Erasers) and their implications in cancer therapy

Keywords: ADA2; Adenosine deaminase 2; ASH1L; Absent, Small, or Homeotic 1-like; BAF; BRG1 associated factor; BAH; Bromoadjacent homology; BAZ2A; Bromodomain adjacent to zinc finger domain protein 2A; BET; Bromodomain and Extra-Terminal domain; BRPF1; Bromodomain a

دانلود رایگان متن کامل مقاله ISI 75 صفحه سال انتشار : 2018 سفارش ترجمه

گیرنده های اسید رتینوئیک: از مکانیسم های مولکولی به درمان سرطان

Retinoic acid receptors: From molecular mechanisms to cancer therapy

Keywords: 4-HPR; N-(4-hydroxyphenyl)retinamide; 5′-UTR; 5′-untranslated region; 9-cis-RA; 9-cis retinoic acid; 9cUAB30; (2E,4E,6Z,8E)-8-(3′,4′-dihydro-1′(2'H)-naphthalen-1′-ylidene)-3,7-dimethyl-2,4,6-octatrienoic acid; Acitretin; (2E,4E,6E,8E)-9-(4-met

دانلود رایگان متن کامل مقاله ISI 416 صفحه سال انتشار : 2015 سفارش ترجمه

هم ریزپردازنده های رونویسی و ذخیره سازی حافظه

Transcriptional co-repressors and memory storage

Keywords: Epigenetics; Memory; Co-repressor; NCOR; SIN3A; Chromatin remodeling

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

مکانیسم عمل گیرنده هورمون تیروئید در طول توسعه: درس های مطالعات دوزیستان

Mechanisms of thyroid hormone receptor action during development: Lessons from amphibian studies

Keywords: TH; Thyroid hormone; TR; Thyroid hormone receptor; T3; 3,5,3′ triiodothyronine; TRE; TH response element; DR; direct repeat; IR; inverted repeat or palindrome; ER; everted repeat; RXR; retinoic acid X receptor; dp; dominant positive; dn; dominant negati

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Differential effects of and mechanisms underlying the protection of cardiomyocytes by liver-X-receptor subtypes against high glucose stress-induced injury

Keywords: Liver-X-receptors; Glucose; Expression; Cardiomyocytes; Oxidative stress; LXR; liver-X-receptor; SUMO; small ubiquitin-like modifier; NCoR; nuclear receptor corepressor; DM; diabetes mellitus; DCM; diabetic cardiomyopathy; ROS; reactive oxygen species; iN

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer's disease

Keywords: AChE; acetylcholine esterase; AD; Alzheimer's disease; AP1; activator protein 1; APP; amyloid precursor protein; Aβ; amyloid beta; BACE1; β-site of APP cleaving enzyme; Bax; Bcl-2-associated X protein; BBB; blood-brain barrier; Bcl-2; B-cell lymphoma

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Ubiquitination/sumoylation: An alternative pathway to modify gene regulation directed by xenosensors

Keywords: Epigenetic regulation; Post-translational modifications; Nuclear receptors; Xenobiotics metabolism; AHR; aryl hydrocarbon receptor; AHRR; aryl hydrocarbon receptor repressor; ARNT; aryl hydrocarbon receptor nuclear translocator; CAR; constitutive androsta

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages

Keywords: Interleukin-4; STAT6; Retinoid X receptor; Macrophage; Chromatin immunoprecipitation; Trancriptome; Cistrome; JAK; Janus tyrosine kinases; STAT; Signal Transducer and Activator of Transcription; IL-4; Interleukin 4; TNFα; tumor necrosis factor alpha; IFN

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Pituitary NR4A1 is negatively regulated by thyroid hormone without direct binding of thyroid hormone receptors on the gene

Keywords: NR4A1; Thyroid hormone; Thyroid hormone receptor β; Pituitary; NCoR;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Heme oxygenase-1 induction by rosiglitazone via PKCα/AMPKα/p38 MAPKα/SIRT1/PPARγ pathway suppresses lipopolysaccharide-mediated pulmonary inflammation

Keywords: Rosiglitazone (PubChem CID: 77999); Lipopolysaccharide (PubChem CID: 11970143); H7 (PubChem: 11957580); Gö6976 (PubChem: 3501); Compound C (PubChem: 11524144); p38VIII (PubChem: 9801969); Sirtinol (PubChem: 5717148); T0070907 (PubChem: 2777391); AMPKα;

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

The challenges and promise of targeting the Liver X Receptors for treatment of inflammatory disease

Keywords: ABC; ATP-Binding Cassette; DR4; direct repeat 4; ER; endoplasmic reticulum; HDL; high density lipoprotein; LDLR; low density lipoprotein receptor; LXR; Liver X Receptor; LXRE; LXR response element; NCoR; nuclear co-repressor; NPC1L1; Niemann-Pick C1-like

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair

Keywords: 15d-PGJ2; 15-deoxy-D12, 14prostaglandin J2; 15(S)-HETE; 15(S)-hydroxyeicosatetraenoic acid; ADP; adenosine diphosphate; AGE; advanced glycan end product; AMPA; α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid; ARE; antioxidant response element; AS; a

دانلود رایگان متن کامل مقاله ISI 75 صفحه سال انتشار : 2018 سفارش ترجمه

Control of viral replication and transcription by the papillomavirus E8^E2 protein

Keywords: Papillomavirus; HPV; E2; E8^E2; NCOR; SMRT; Replication; Repressor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Anti-androgenic mechanisms of Bisphenol A involve androgen receptor signaling pathway

Keywords: AR; androgen receptor; BPA; Bisphenol A; EDCs; endocrine-disrupting chemicals; DHT; dihydrotestosterone; AREs; androgen response elements; N/C; amino- and carboxyl-terminal regions; SRC-1; steroid receptor coactivator-1; SMRT; silencing mediator of retino

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Zbtb7c is a molecular 'off' and 'on' switch of Mmp gene transcription

Keywords: MMP; matrix metalloproteinase; TNFα; tumor necrosis factor alpha; Kr-pok; kidney cancer related POZ domain and Krüppel-like protein; Jnk; c-Jun N-terminal kinase; Zbtb7c (Kr-pok); Mmps; c-Jun; NCoR; p-Jnk;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Nuclear receptor corepressors Ncor1 and Ncor2 (Smrt) are required for retinoic acid-dependent repression of Fgf8 during somitogenesis

Keywords: Caudal progenitors; Somitogenesis; Nuclear receptor corepressor; NCOR; SMRT; Fgf8; Retinoic acid response element; CRISPR/Cas9 gene editing;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Regulation of corepressor alternative mRNA splicing by hormonal and metabolic signaling

Keywords: Transcriptional regulation; Corepressors; Alternative mRNA splicing; SMRT; NCoR; Isoforms

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancers

Keywords: Cytokine; Estrogen; Sex hormone; SIAH1; SIAH2; ACK1/TNK2; activated CDC42-associated kinase 1; AR; androgen receptor; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia mutated related; BF; biochemical failure; DCC; deleted in colorectal cance

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

L312, a novel PPARγ ligand with potent anti-diabetic activity by selective regulation

Keywords: BAT; Brown adipose tissue; CBP; cAMP responsive element binding protein (CREBP) binding protein; CDK5; Cyclin-dependent kinase 5; EC50; half-maximal effective concentration; FFA; Free fatty acids; HOMA-IR; HOMA of insulin resistance; ITT; Insulin toleranc

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

miR-200c-SUMOylated KLF4 feedback loop acts as a switch in transcriptional programs that control VSMC proliferation

Keywords: ATRA; all-trans retinoic acid; cdk2; cyclin-dependent kinase 2; HASMC; human aortic smooth muscle cell; HDAC2; histone deacetylase 2; KLF; Krüppel-like factor; LSD1; lysine-specific demethylase 1; miR; microRNA; NCoR; nuclear receptor corepressor; p21; p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Fundamentals of vitamin D hormone-regulated gene expression

Keywords: VDR; vitamin D receptor; ChIP; chromatin immunoprecipitation; ChIP-chip; ChIP coupled to tiled microarrays; ChIP-seq; ChIP coupled to deep sequencing methods; VDRE; vitamin D response element; NGS; Next Generation Sequencing; RXR; retinoid X receptor; VDI

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of a novel partial agonist of liver X receptor α (LXRα) via screening

Keywords: ABC; ATP-binding cassette; ApoE; apolipoprotein E; DRIP205; vitamin D receptor-interacting protein 205; FAS; fatty acid synthase; GAPDH; glyceraldehyde-phosphate dehydrogenase; HDL; high-density lipoprotein; LBD; ligand-binding domain; LXR; liver X recept

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Cyclic AMP enhances progesterone action in human myometrial cells

Keywords: cAMP; cyclic AMP; NCoR; nuclear receptor co-repressor; PR; progesterone receptor; PRE; progesterone response element; SMRT; silencing mediator for retinoid and thyroid hormone receptor; Human myometrial cells; cAMP; Progesterone; Cyclo-oxygenase-2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

HDAC3 interacts with sumoylated C/EBPα to negatively regulate the LXRα expression in rat hepatocytes

Keywords: CBS; C/EBPα binding site; C/EBPs; CCAAT/enhancer binding proteins; ChIP; chromatin immunoprecipitation assay; Co-IP; co-immunoprecipitation; CYP7A1; cholesterol 7α-hydroxylase; FAS; fatty acid synthase; HDAC; histone deacetylase; HFD-MetS; high-fat-diet

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

ATP-binding cassette transporter A1 and HDL metabolism: effects of fatty acids

Keywords: ApoA-I; apolipoprotein A-I; ABCA1; ATP-binding cassette transporter A1; CETP; cholesterol ester transfer protein; CHD; coronary heart disease; EPA; eicosapentaenoic acid; HDAC; histone deacetylase; HDL; high-density lipoprotein; HDL-C; HDL cholesterol; LC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleLigand-dependent corepressor acts as a novel corepressor of thyroid hormone receptor and represses hepatic lipogenesis in mice

Keywords: LCOR; ligand-dependent corepressor; ob/ob; leptin-deficient; TR; thyroid hormone receptor; TH; thyroid hormone; SRC; steroid receptor coactivators; PGC-1; peroxisome proliferator-activated receptor gamma coactivator-1; NCOR; nuclear receptor corepressor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Protective role of the vitamin D receptor

Keywords: VDR; vitamin D receptor; RAS; renin-angiotensin system; VDRA; vitamin D receptor agonists; VDRE; vitamin D response elements; RXR; retinoid X receptors; SRC; steroid receptor activator complex; DRIP; vitamin D receptor interacting protein complex; NCoR; n

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Putting the brakes on continued androgen receptor signaling in castration-resistant prostate cancer

Keywords: AAG; 17-N-allylamino-17-demethoxygeldanamycin; ACTH; adrenocorticotropic hormone; AR; androgen receptor; cAMP; cyclic adenosine monophosphate; CREB; cAMP response element-binding; CRPC; castration-resistant prostate cancer; CYP; cytochrome P450; DHEA; deh

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Anti-inflammatory and metabolic actions of FXR: Insights into molecular mechanisms

Keywords: AF1; activation function 1; ANIT; α-naphthylisothiocyanate; AR; androgen receptor; BA; bile acids; BDL; bile duct ligation; ChIP-seq; chromatin immunoprecipitation-sequencing; DBD; DNA binding domain; DR; direct repeat; ER; estrogen receptor; FXR; farnes

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Epigenetic organization of brain sex differences and juvenile social play behavior

Keywords: Epigentic; Methylation; Methyl-binding proteins; Sex differences; Juvenile social play; Corepressor; MeCP2; NCoR; Estrogen receptors; Amygdala; Preoptic area

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

HDAC3 and the molecular brake pad hypothesis

Keywords: Long-term memory; Epigenetics; HDAC; HAT; NCoR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Thyroid hormone suppression of β-amyloid precursor protein gene expression in the brain involves multiple epigenetic regulatory events

Keywords: APP; β-amyloid precursor protein; CDS; charcoal/dextran-stripped; ChIP; chromatin immunoprecipitation; FBS; fetal bovine serum; H3-Ac; acetylated histone H3; HDAC; histone deacetylase; HKDM; histone lysine demethylase; H3K4; histone H3 lysine 4; H3K4-2me

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Corepressor effect on androgen receptor activity varies with the length of the CAG encoded polyglutamine repeat and is dependent on receptor/corepressor ratio in prostate cancer cells

Keywords: Androgen receptor; Polyglutamine; Corepressor; SMRT; NCoR; Prostate cancer risk

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Cell cycle regulated expression of NCoR might control cyclic expression of androgen responsive genes in an immortalized prostate cell line

Keywords: AR; androgen receptor; ARBS3.12AR; binding site on chromosome 3; ARE; androgen response element; CBP; calmoduline binding peptide; CDK4; cyclin dependent kinase 4; ChIP; chromatin immunoprecipitation; CYR61; cysteine-rich, angiogenic inducer, 61; DNA; deo

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Vitamin D receptor binds to the ε germline gene promoter and exhibits transrepressive activity

Keywords: Vitamin D receptor; calcitriol; ε germline transcript; class-switch recombination; IgE; histone acetylation; AcH; Acetylated histone; As2O3; Arsenic-(III)-oxide; CH; Constant heavy chain; ChIP; Chromatin immunoprecipitation; CSR; Class-switch recombinati

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Bag-1M inhibits the transactivation of the glucocorticoid receptor via recruitment of corepressors

Keywords: Bag-1; Bcl-2 associated athanogene 1; GR; glucocorticoid receptor; GRmt; glucocorticoid receptor K496L/I497G mutant; Hsp; heat shock protein; hMTIIa; human metallothionein IIa; ChIP; chromatin immunoprecipitation; siRNA; small interfering RNA; IB; immunob

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

SMRT has tissue-specific isoform profiles that include a form containing one CoRNR box

Keywords: SMRT; NCoR; CoRNR box; Corepressors; Alternative splicing; Nuclear receptors; Tissue specificity; Paralogues; EST; Xenopus;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Nuclear hormone receptor co-repressors

Keywords: Co-repressor; Gene silencing; Chromatin; Transcription; Ligand-regulation; SMRT; NCoR; N-CoR; Hairless; Alien; PSF; SUN-CoR; RIP140;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Smads and chromatin modulation

Keywords: AER; apical ectodermal ridge; ACF; ATP-utilizing chromatin assembly and remodeling factor; AML; acute myeloid leukaemia; AMT; arginine methyl transferase; ARC; activator-recruited cofactor; BAF; BRG1/hBRM-associated factors; BMP; bone morphogenic protein;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2005 سفارش ترجمه

Macrocephaly and the control of brain growth in autistic disorders

Keywords: ACTH; adrenocorticotropin hormone; DNA; deoxyribonucleic acid; EGF; epidermal growth factor; ES; embryonic stem cells; FGF2; fibroblast growth factor 2; FMR-1; fragile X mental retardation 1; FMRP; fragile X mental retardation protein; FoxP2; forkhead box

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2005 سفارش ترجمه