Identification and characterization of the RNA-binding protein Rbfox3 in zebrafish embryo
Keywords: Alternative splicing; NeuN; RNA-binding protein; Zebrafish Rbfox3;
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N-methyl-d-aspartate receptor NR2B subunit involved in depression-like behaviours in lithium chloride-pilocarpine chronic rat epilepsy model
Keywords: DG; dentate gyrus; EWD; epilepsy with depression; EWND; epilepsy without depression; FST; forced swim test; 1H-MRS; proton magnetic resonance spectroscopy; IMT; immobility time; Licl; lithium chloride; NeuN; neuronal specific nuclear protein; NMDA; N-meth
Curcumin-loaded embryonic stem cell exosomes restored neurovascular unit following ischemia-reperfusion injury
Keywords: AchE; acetylcholinestrase; BBB; blood brain barrier; BSA; bovine serum albumin; cDNA; complimentary DNA; DAPI; 4,6-diamidino-2-phenyl-indole HCl; FIU; fluorescence intensity units; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GFAP; glial fibrillary ac
Recombinant Slit2 attenuates neuroinflammation after surgical brain injury by inhibiting peripheral immune cell infiltration via Robo1-srGAP1 pathway in a rat model
Keywords: SBI; surgical brain injury; Robo1; roundabout1; CD45; cluster of differentiation 45; MPO; myeloperoxidase; srGAP1; Slit-Robo GTPase activating protein 1; ELISA; enzyme linked immunosorbent assay; ICV; intracerebroventricular; PBS; phosphate buffered salin
Decline of microtubule-associated protein tau after experimental stroke in differently aged wild-type and 3xTg mice with Alzheimer-like alterations
Keywords: Cy; Carbocyanine; NeuN; Neuronal Nuclei; TBS; Tris-buffered saline; ischemic stroke; tau; microtubule; cytoskeleton;
Intrathecal CGS-26303 Pretreatment Attenuates Spinal Nerve Ligation-Induced Neuropathic Pain in the Spinal Cord
Keywords: Astrocyte; ETAR; Microglia; MMP-2; MMP-9; Neuropathic pain; CGS-2630; 3 (S)-2 biphenyl-4yl-1-(1H-tetrazol-5-yl)-ethyl-amino-methyl phosphonic acid; CNS; Central nervous system; DRG; Dorsal root ganglia(on); ECE; Endothelin-converting enzyme; ET-1; Endothe
Recombinant Adeno Associated Viral (AAV) vector type 9 delivery of Ex1-Q138-mutant huntingtin in the rat striatum as a short-time model for in vivo studies in drug discovery
Keywords: HD; Huntington's disease; mHTT; mutant Huntingtin; rAAV; recombinant Adeno Associated Virus; LV; lentivirus; tNAA; total N-Acetyl Aspartate; Myo-Ins; myoinositol; GFP; green fluorescent protein; NeuN; neuronal nuclei; DARPP-32; dopamine- and cyclic AMP-re
Imaging mass spectrometry detects dynamic changes of phosphatidylcholine in rat hippocampal CA1 after transient global ischemia
Keywords: AA; arachidonic acid; DHA; docosahexaenoic acid; ED1; ectodermal dysplasia 1; GFAP; glial fibrillary acidic protein; IMS; imaging mass spectrometry; MALDI; matrix-assisted laser desorption/ionization; NeuN; neuronal nuclei; PC; phosphatidylcholine; RT; ro
Targeting the nNOS/peroxynitrite/calpain system to confer neuroprotection and aid functional recovery in a mouse model of TBI
Keywords: BH4; tetrahydrobiopterin; CCI; controlled cortical impact; FeTPPS; 5,10,15,20-tetrakis(4-sulfonatophenyl) porphyrinato iron (III); HgCl2; mercuric chloride; GSNO; S-nitrosoglutathione; MBP; myelin basic protein; NeuN; neuronal nuclear protein; 7-NI; 7-nit
Up-regulation of neurofilament light chains is associated with diminished immunoreactivities for MAP2 and tau after ischemic stroke in rodents and in a human case
Keywords: Cy; carbocyanine; eMCAO; embolic middle cerebral artery occlusion; GFAP; glial fibrillary acidic protein; LEA; Lycopersicon esculentum agglutinin; MAP2; microtubule-associated protein 2; NeuN; neuronal nuclei; NF-L; neurofilament light chain; STL; Solanum
Neurogenic effect of VEGF is related to increase of astrocytes transdifferentiation into new mature neurons in rat brains after stroke
Keywords: Stroke; Neural network; Neurogenesis; Neurovascular unit; Astroglial; BrdU; 5â²-bromodeoxyuridine; EGFP; enhanced green fluorescence protein; FC; fluorocitrate; GFAP; glial fibrillary acidic protein; GFP; green fluorescent protein; MAP-2; microtubule-ass
Rho kinase inhibition following traumatic brain injury in mice promotes functional improvement and acute neuron survival but has little effect on neurogenesis, glial responses or neuroinflammation
Keywords: Rho GTPase; Astrocytic gliosis; Y27632; Fasudil; Microglia; Controlled cortical impact; Horizontal ladder test; NeuN;
Clonidine ameliorates cognitive impairment induced by chronic cerebral hypoperfusion via up-regulation of the GABABR1 and GAD67 in hippocampal CA1 in rats
Keywords: Clonidine; Two-vessel occlusion; NeuN; GAD67; GABABR1
Icariin decreases both APP and Aβ levels and increases neurogenesis in the brain of Tg2576 mice
Keywords: AD; Alzheimer's disease; Aβ; amyloid-β peptide; ANOVA; one-way analysis of variance; APP; amyloid-β precursor protein; BCA; bicinchoninic acid; BrdU; 5-bromo-2-deoxyuridine; DG; dentate gyrus; ELISA; enzyme-linked immunosorbent assay; NeuN; neuron-sp
Memantine exerts functional recovery by improving BDNF and GDNF expression in 3-nitropropionic acid intoxicated mice
Keywords: Memantine; 3NP; BDNF; GDNF; NeuN; GFAP;
Low concentrations of methylmercury inhibit neural progenitor cell proliferation associated with up-regulation of glycogen synthase kinase 3β and subsequent degradation of cyclin E in rats
Keywords: MeHg, methylmercury; NPCs, neural progenitor cells; GSK-3β, glycogen synthase kinase 3β; CDK, cyclin-dependent kinase; MTS, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl-2H-tetrazolium, inner salt); BrdU, bromodeoxyuridine; NeuN
Group 1 mGlu-family proteins promote neuroadaptation to ethanol and withdrawal-associated hippocampal damage
Keywords: CIE; Chronic intermittent ethanol; mGlu; Metabotropic glutamate receptor; NeuN; Neuron specific nuclear protein;
Toxic effect of aflatoxin B1 and the role of recovery on the rat cerebral cortex and hippocampus
Keywords: Aflatoxin B1; Cerebral cortex; Hippocampus; Histopathology; GFAP; NeuN
Reduction of inflammatory responses by l-serine treatment leads to neuroprotection in mice after traumatic brain injury
Keywords: l-serine; Mouse; Traumatic brain injury; Neuroprotection; Inflammatory response; Glycine receptor; ELISA; enzyme-linked immunosorbent assay; GFAP; glial fibrillary acidic protein; Iba-1; ionized calcium binding adapter molecule-1; IL-1β; interleukin-1β;
Overexpression of tissue-nonspecific alkaline phosphatase increases the expression of neurogenic differentiation markers in the human SH-SY5Y neuroblastoma cell line
Keywords: 36B4; ribosomal protein, large, P0; AADC; aromatic l-amino acid decarboxylase; AD; Alzheimer's disease; ALPL/TNAP/Akp2; tissue-nonspecific alkaline phosphatase; AT; annealing temperature; ATP; adenosine triphosphate; ADP; adenosine diphosphate; AMP; adeno
Peptide fragment of thymosin β4 increases hippocampal neurogenesis and facilitates spatial memory
Keywords: Ac-SDKP; N-acetyl-serylaspartyl-lysyl-proline; ANOVA; one-way analysis of variance; BrdU; 5-bromo-2â²-deoxyuridine; DCX; doublecortin; DG; dentate gyrus; GFAP; glial fibrillary acidic protein; GSK-3β; glycogen synthase kinase-3β; NeuN; neuronal nuclei;
The basolateral nucleus of the amygdala mediates caloric sugar preference over a non-caloric sweetener in mice
Keywords: ANCOVA; analysis of covariance; ANOVA; analyses of variance; AP; anteroposterior; BLA; basolateral nucleus of the amygdala; CeA; central nucleus of the amygdala; DV; dorsoventral; ML; mediolateral; NeuN; neuronal nuclei; PB; phosphate buffer; PBS; phospha
Entorhinal cortical defects in Tg2576 mice are present as early as 2-4Â months of age
Keywords: Entorhinal cortex; Retrosplenial cortex; Prefrontal cortex; Object placement; NeuN; Excitability;
Research reportThe effects of chronic fluoxetine treatment following injury of medial frontal cortex in mice
Keywords: BrdU; 5-bromo-2â²-deoxyuridine; dH2O; distilled water; EPM; elevated plus maze; GCL; granule cell layer; MFC; medial frontal cortex; MWT; Morris water task; NeuN; neuronal nuclei; PBS; phosphate buffered saline; PFA; paraformaldehyde; SSRI; selective ser
HAMI 3379, a CysLT2R antagonist, dose- and time-dependently attenuates brain injury and inhibits microglial inflammation after focal cerebral ischemia in rats
Keywords: Blood-brain barrier; BBB; CSF; cerebrospinal fluid; CysLT1R; cysteinyl leukotriene receptor 1; CysLT2R; cysteinyl leukotriene receptor 2; CysLTs; cysteinyl leukotrienes; DMSO; dimethyl sulfoxide; GFAP; glial fibrillary acidic protein; Iba-1; ionized cal
Involvement of p38 MAPK activation mediated through AT1 receptors on spinal astrocytes and neurons in angiotensin II- and III-induced nociceptive behavior in mice
Keywords: Angiotensin II; Angiotensin III; AT1 receptors; Nociceptive behavior; p38 MAPK; Astrocyte; Neuron; Intrathecal administration; Mice; Ang; angiotensin; AT1; Ang II type 1; AT2; Ang II type 2; i.t.; intrathecal; MAPK; mitogen-activated protein kinase; ACE;
Cuprizone decreases intermediate and late-stage progenitor cells in hippocampal neurogenesis of rats in a framework of 28-day oral dose toxicity study
Keywords: ARC; activity-regulated cytoskeleton-associated protein; BDNF; brain-derived neurotrophic factor; BLBP; brain lipid binding protein; CALB1; calbindin-D-28K; CALB2; calbindin-D-29K; CHRNA7; cholinergic receptor, nicotinic, alpha polypeptide 7; CNS; central
Altered subcellular localization of the NeuN/Rbfox3 RNA splicing factor in HIV-associated neurocognitive disorders (HAND)
Keywords: NeuN; Rbfox3; HIV-associated neurocognitive disorders; Splicing; Neurodegeneration; Gene expression;
Basic NeuroscienceMouse hippocampal explant culture system to study isolated axons
Keywords: CNS; central nervous system; PNS; peripheral nervous system; Neun; neuronal specific nuclear protein; Neuron; Brain; Hippocampus; Injury; Tissue explant; Axon; CNS regeneration;
Research ReportGhrelin alleviates early brain injury after subarachnoid hemorrhage via the PI3K/Akt signaling pathway
Keywords: SAH; subarachnoid hemorrhage; EBI; early brain injury; CNS; central nervous system; NeuN; neuron specific nuclear protein; Ghrelin; Early brain injury; Subarachnoid hemorrhage; PI3K/Akt;
Early reperfusion injury is associated to MMP2 and IL-1β elevation in cortical neurons of rats subjected to middle cerebral artery occlusion
Keywords: ANOVA; analysis of variance; BBB; blood-brain barrier; DAPI; 4â²,6-diamidino-2-phenylindole dihydrochloride; DMSO; dimethyl sulfoxide; DQ; dye-quenched; ELISA; enzyme-linked immunosorbent assay; FITC; fluorescein isothiocyanate; IL; interleukin; MCAo;
Phosphorylation enhances recombinant HSP27 neuroprotection against focal cerebral ischemia in mice
Keywords: BBB; blood-brain barrier; BSA; bovine serum albumin; FITC; fluorescein isothiocyanate; HSP27; heat shock protein 27; hHSP27; HSP27, purified from human lymphocytes; Iba-1; ionized calcium binding adapter molecule-1; MCAO; middle cerebral artery occlusio
Neuroprotective effects of Gualou Guizhi decoction in vivo and in vitro
Keywords: GLGZD; Gualou Guizhi Decotion; MCAO; middle cerebral artery occlusion; NMDA; N-methyl-d-aspartic acid; TTC; 2,3,5-triphenyl tetrazolium chloride; TUNEL; Terminal transferase dUTP nick end labeling; NeuN; neuron-specific nuclear; MAP-2; microtubule-associa
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces expression of p27kip1 and FoxO3a in female rat cerebral cortex and PC12 cells
Keywords: TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; AhR; aryl hydrocarbon receptor; CNS; central nervous system; FBS; fetal bovine serum; FoxO3a; forkhead box class O 3a; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GFAP; glial fibrillary acidic protein; NeuN;
Ecdysterone protects gerbil brain from temporal global cerebral ischemia/reperfusion injury via preventing neuron apoptosis and deactivating astrocytes and microglia cells
Keywords: EDS; ecdysterone; NeuN; neuronal nuclei; TNF-α; tumor necrosis factor alpha; BCA; bicinchoninic acid; GFAP; glial fibrillary acidic protein; lba-1; lupus brain antigen 1; IL-1β; interleukin-1β; IL-6; interleukin-6; Ecdysterone; Caspase-3; Tumor necrosi
Regular ArticleChemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2
Keywords: CFA; complete Freund's adjuvant; COX-2; cyclooxygenase-2; ERK; extracellular signal-regulated kinase; GFAP; glial fibrillary acidic protein; NeuN; neuron-specific nuclear protein; NMDA; N-methyl-d-aspartate; RT-PCR; real-time quantitative polymerase chain
56Fe particle exposure results in a long-lasting increase in a cellular index of genomic instability and transiently suppresses adult hippocampal neurogenesis in vivo
Keywords: LET; linear energy transfer; HZE; high-energy, high charge nuclei; GCR; galactic cosmic radiation; GFP; green fluorescent protein; YFP; yellow fluorescent protein; SGZ; subgranular zone; DG; dentate gyrus; BrdU; 5-bromo-2â²-deoxyuridine; DCX; doublecorti
Basic NeuroscienceAutomated immunohistochemical method to quantify neuronal density in brain sections: Application to neuronal loss after status epilepticus
Keywords: DAPI; 4â²,6â²-diamidino-2-phenylindole; NeuN; neuronal nuclei; PBS; phosphate buffered saline; SE; status epilepticus; Excitotoxicity; Epilepsy; Quantification; ImageJ; Neuroanatomy; Microscopy;
Blocked angiogenesis in Galectin-3 null mice does not alter cellular and behavioral recovery after middle cerebral artery occlusion stroke
Keywords: ace tub; acetylated tubulin; ANOVA; analysis of variance; β-cat; β-catenin; BrdU; 5-bromo-2-deoxyuridine; CBF; cerebral blood flow; CSF; cerebrospinal fluid; Dcx; doublecortin; ECM; extracellular matrix; γ-tub; gamma-tubulin; Gal-3; Galectin-3; GFAP; g
Distribution and morphological characteristics of striatal interneurons expressing calretinin in mice: A comparison with human and nonhuman primates
Keywords: BAC; bacterial artificial chromosome; ChAT; choline acetyltransferase; CR; calretinin; D1/D2; Drd1a-tdTomato/Drd2-EGFP; GABA; γ-aminobutyric acid; LV; lateral ventricle; NeuN; neuronal nuclear antigen; PB; sodium phosphate buffer; PBS; sodium phosphate b
Chronic tooth pulp inflammation induces persistent expression of phosphorylated ERK (pERK) and phosphorylated p38 (pp38) in trigeminal subnucleus caudalis
Keywords: ANOVA; analysis of variance; AOI; area of interest; CFA; complete Freund's adjuvant; Cy3; indocarbocyanine; EMG; electromyogram; ERK; extracellular signal-regulated kinase; FITC; fluorescein isothiocyanate; GFAP; glial fibrillary acidic protein; JOR; Ja
The high-mobility group I-Y transcription factor is involved in cerebral ischemia and modulates the expression of angiogenic proteins
Keywords: ANGPT-1; angiopoietin 1; CCA; common carotid arteries; ChIP; chromatin immunoprecipitation; DAPI; 4â²,6-diamidino-2-phenylindole; GFAP; glial fibrillary acidic protein; HMGIY/HMGA1; high-mobility group I-Y protein; MTT; 3-(4,5-dimethylthiazol)-2,5-diphen
Region-specific expression of Dickkopf-like1 in the adult brain Abbreviated title: Dkkl1 in the adult brain
Keywords: βgal; β-galactosidase; Dkkl1; Dickkopf-like1; GAPDH; glycerinaldehyd-3-phosphat-dehydrogenase; Ct; threshold cycle number; PB; phosphate buffer; NeuN; neuronal nuclear antigen; Dkkl1; Mouse cortex; Apoptosis; Adult nervous system;
Quantitative evaluation of MRI and histological characteristics of the 5xFAD Alzheimer mouse brain
Keywords: 5xFAD; Five familial Alzheimer's disease mutations; Aβ; β-Amyloid; AD; Alzheimer's disease; FOV; Field of view; H; Hippocampus; LC; Lower cortex; MBP; Myelin basic protein; MRI; Magnetic resonance imaging; NeuN; Neuron-specific nuclear protein; ROI; Reg
Fndc5 knockdown significantly decreased neural differentiation rate of mouse embryonic stem cells
Keywords: BSA; bovine serum albumin; CMV; cytomegalovirus; DAPI; 4,6-diamidio-2-phenylindole; DMEM; Dulbecco's modified Eagle's medium; Dox; doxycycline; EBs; embryoid bodies; ES-FCS; ES-qualified fetal calf serum; Fndc5; fibronectin type III domain-containing
Studying the cerebellar DNA damage response in the tissue culture dish
Keywords: 53BP1; p53 binding protein 1; AOA1/2; ataxia with oculomotor apraxia type 1; A-T; ataxia-telangiectasia; A-TLD; ataxia-telangiectasia-like disorder/disease; ATM; ataxia-telangiectasia, mutated; ATR; ATM- and Rad3-related protein kinase; CaBP; calbindin pr
Chicken immunoregulatory Ig-like receptor families: An overview and expression details on ggTREM-A1
Keywords: CD200R; CD200 receptor; CD300L; CD300 like antigen; CHIR; chicken Ig-like receptor; Ct; cycle threshold; DAP; DNAX activating protein; FcR; Fc receptor; GFAP; glial fibrillary acidic protein; ITAM; immunoreceptor tyrosine-based activating motif; ITIM; imm
Chronic d-amphetamine administered from childhood to adulthood dose-dependently increases the survival of new neurons in the hippocampus of male C57BL/6J mice
Keywords: ADHD; attention deficit hyperactivity disorder; BDNF; brain-derived neurotrophic factor; BrdU; bromodeoxyuridine; Dcx; doublecortin; NeuN; neuronal nuclear protein; PND; post natal day; TBS; tissue-buffering solution; neurogenesis; hippocampus; mouse; dru
PPARγ activation prevents impairments in spatial memory and neurogenesis following transient illness
Keywords: Adult neurogenesis; Hippocampus; Water maze; Spatial memory; Lipopolysaccharide; Neuroinflammation; NSAID; Indomethacin; Rosiglitazone; C57Bl/6 mice; Doublecortin; NeuN;
Research ReportEndothelin B receptor agonist, IRL-1620, enhances angiogenesis and neurogenesis following cerebral ischemia in rats
Keywords: MCAO; middle cerebral artery occlusion; SVZ; subventricular zone; VEGF; vascular endothelial growth factor; NeuN; neuronal nuclei; GFAP; glial fibrillary acidic protein; BrdU; bromodeoxyuridine; NGF; nerve growth factor; ET; endothelin; Endothelin B recep