Immune signature of urothelial cancer associated with grade, recurrence, and invasion
Keywords: NFKB; Urothelial cancer; Cytokines; NFκB; CTLA4;
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Adiponectin limits monocytic microparticle-induced endothelial activation by modulation of the AMPK, Akt and NFκB signaling pathways
Keywords: NFKB; Adiponectin; AMPK; Endothelial cell; Monocyte; Microparticles; NFκB;
Efficacy comparison of lyophilised black raspberries and combination of celecoxib and PBIT in prevention of carcinogen-induced oesophageal cancer in rats
Keywords: NFKB; Black raspberries; Anthocyanin; Oesophageal cancer; Cancer prevention; NMBA (PubChem CID: 13643); PBIT (PubChem CID: 935415); Celecoxib (PubChem CID: 2662); SCC; squamous cell carcinoma; iNOS; inducible nitric oxide synthase; COX-2; cyclooxygenase-2; PBIT
Positive feedback role of TRPC3 in TNF-α-mediated vasogenic edema formation induced by status epilepticus independent of ETB receptor activation
Keywords: NFKB; ANOVA; analyzed by one-way analysis of variance; BBB; brain-blood barrier; DAB; 3,3-diaminobenzidine; DTT; dithiothreitol; eNOS; endothelial nitric oxide synthase; ET-1; endothelin-1; NFκB; nuclear factor-κB; NO; nitric oxide; PC; piriform cortex; RCA
Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein β-CCAAT-enhancer-binding protein α activation
Keywords: NFKB; AP; acute pancreatitis; ATF6; activating transcription factor 6; BSA; bovine serum albumin; CCK-8; cholecystokinin-8; C/EBP; CCAAT-enhancer-binding protein; CHOP; CCAAT/enhancer binding protein (C/EBP) homologous protein; eIF2; αeukaryotic translation in
Matricellular Protein CCN5 Reverses Established Cardiac Fibrosis
Keywords: NFKB; apoptosis; gene therapy; heart failure; NFκB; AAV; adeno-associated virus; CF; cardiac fibrosis; EndMT; endothelial-mesenchymal transition; FACS; fluorescence-activated cell sorting; HCAEC; human coronary artery endothelial cell; HF; heart failure; LV; l
Carbamylated Low-Density Lipoproteins Induce a Prothrombotic State Via LOX-1
Keywords: NFKB; aggregation; arterial thrombosis; chronic kidney disease; platelets; vascular smooth muscle cells; AoSMC; aortic smooth muscle cell; CKD; chronic kidney disease; cLDL; carbamylated low-density lipoprotein; HAEC; human aortic endothelial cell; LDL; low-de
Coenzyme Q0 regulates NFκB/AP-1 activation and enhances Nrf2 stabilization in attenuation of LPS-induced inflammation and redox imbalance: Evidence from in vitro and in vivo studies
Keywords: NFKB; AP-1; activator protein-1; ARE; antioxidant response element; ATF2; activating transcription factor 2; CoQ0; coenzyme Q0; COX-2; cyclooxygenase-2; ERK; extracellular signal-regulated kinase; GSH; glutathione; HO-1; heme oxygenase-1; I-κB; inhibitor-κB;
Differential Regulation of CXCL8 Production by Different G Protein Subunits with Synergistic Stimulation by Gi- and Gq-Regulated Pathways
Keywords: NFKB; ELR; Glu-Leu-Arg; GPCRs; G protein-coupled receptors; NFκB; nuclear factor κB; STAT3; signal transducer and activator of transcription 3; MEM; minimum essential media; FLIPR; fluorometric imaging plate reader; G protein-coupled receptors; CXCL8; interle
In vitro and in vivo assessment of meadowsweet (Filipendula ulmaria) as anti-inflammatory agent
Keywords: NFKB; FUA; F. ulmaria aerial part extract; FUR; F. ulmaria root extract; COX-1; cyclooxygenase-1; COX-2; cyclooxygenase-2; LOX; lipoxygenase; NSAIDs; nonsteroidal anti-inflammatory drugs; HPTLC; high performance thin layer chromatography; HPLC; high performance
Steroid sulfatase in the human MG-63 preosteoblastic cell line: Antagonistic regulation by glucocorticoids and NFκB
Keywords: NFKB; Steroid sulfatase; Regulation; Osteoblast; Glucocorticoid; Dexamethasone; Differentiation; NFκB; Inflammation; Bone;
Toll-like receptor-3 mediates HIV-1 transactivation via NFκB and JNK pathways and histone acetylation, but prolonged activation suppresses Tat and HIV-1 replication
Keywords: NFKB; TLR3; HIV; Viral transactivation; LTR; NFκB; JNK; STAT1; Histone acetylation; Epigenetics; Human monocyte-derived macrophages; TZM-bl; U38 cells; AP-1; activator protein-1; B2M; beta-2-microglobulin; BCA; bicinchoninic acid; CAT; chloramphenicol acetyltr
Role of PTEN in TNFα induced insulin resistance
Keywords: NFKB; Diabetes; Insulin resistance; Hepatocytes; Obesity; Adipocyte; VO-OHpic; 3- hydroxypicolinate vanadium (IV) complex; CDC; Center for Disease Control; MEM; Eagles minimal essential medium; FBG; fasting blood glucose; TG; fasting plasma triglyceride; IR; in
Anticancer drug bortezomib increases interleukin-8 expression in human monocytes
Keywords: NFKB; Bortezomib; Interleukin-8; Macrophages; Monocytes; NFκB; p38 MAPK;
Synthesis of novel C5-curcuminoid-fatty acid conjugates and mechanistic investigation of their anticancer activity
Keywords: NFKB; C5-curcuminoids synthesis; Anticancer agents; NFκB; Apoptosis; DNA topoisomerase I;
Vitamin D compounds reduce mammosphere formation and decrease expression of putative stem cell markers in breast cancer
Keywords: NFKB; 1α,25(OH)2D3; 1α,25-dihydroxyvitamin D3; BCSC; breast cancer stem cell; DCIS; ductal carcinoma in situ; GATA3; GATA binding protein 3; IDC; invasive ductal carcinoma; KLF4; Kruppel-like factor 4; MFE; mammosphere forming efficiency; NFκB; nuclear facto
Low expression of IL-6 and TNF-α correlates with the presence of the nuclear regulators of NF-κB, IκBNS and BCL-3, in the uterus of mice
Keywords: NFKB; IκBNS; nuclear factor of κ light polypeptide gene enhancer in B-cells inhibitor delta; BCL-3; B-cell lymphoma 3-encoded protein; NFκB; nuclear factor kappa-light-chain-enhancer of activated B cells; LPS; lipopolysaccharide; LIF; leukemia inhibitory fac
MALT1 induced immune response is governed by miR-2909 RNomics
Keywords: NFKB; MALT1; paracaspase mucosa-associated lymphoid tissue 1; RIG1; retinoic acid-inducible gene 1; IFN-β; interferon-β; APOBEC3G; apo-lipoprotein B mRNA-editing, enzyme-catalytic, polypeptide-like 3G; CCL5; chemokine (C-C motif) ligand 5; IL-17; interleuki
Antitumor progression potential of morusin suppressing STAT3 and NFκB in human hepatoma SK-Hep1 cells
Keywords: NFKB; Hepatoma; SK-Hep 1 cells; NFκB; Morusin; STAT3; Tumor progression;
The intracerebroventricular injection of rimonabant inhibits systemic lipopolysaccharide-induced lung inflammation
Keywords: NFKB; ICV; intracerebroventricular; CB1; cannabinoid receptor type 1; LPS; lipopolysaccharide; IV; intravenous; Ppc; pulmonary capillary pressure; TLR4; toll-like receptor 4; IRAK1; interleukin receptor-associated kinase-1; IκBα; inhibitor of nuclear factor o
Research ReportInvolvement of NFκB signaling in mediating the effects of GRK5 on neural stem cells
Keywords: NFKB; AD; Alzheimer׳s disease; GPCR; G protein-coupled receptor; GRK; G-protein receptor kinase; IL-6; interleukin-6; IL-1β; interleukin-1β; NAC; N-acetyl cysteine; NFκB; nuclear factor κB; NPCs; neural progenitor cells; NSCs; neuron stem cells; PKA; prote
Combination of low dose major n3 PUFAs in fresh water mussel lipid is an alternative of EPA-DHA supplementation in inflammatory conditions of arthritis and LPS stimulated macrophages
Keywords: NFKB; ACP; acid phosphatase; ALP; alkaline phosphatase; ALA; α-linolenic acid; DAPI; 4â²,6-diamidino-2-phenylindole; DHA; docosahexaenoic acid; DMSO; dimethyl sulphoxide; DPA; docosapentaenoic acid; DCFH-DA; 2â²,7â² dichloro dihydro fluorescin diacetate; EP
Regulation and function of Myb-binding protein 1A (MYBBP1A) in cellular senescence and pathogenesis of head and neck cancer
Keywords: NFKB; DNA damage; Stress response; Treatment failure; Cancer; MYBBP1A; Myb-binding protein 1A; OPSCC; oropharyngeal squamous cell carcinoma; HNSCC; head and neck squamous cell carcinoma; SA-β-Gal; senescence-associated β-galactosidase; SAHF; senescence-associ
A pterostilbene derivative suppresses osteoclastogenesis by regulating RANKL-mediated NFκB and MAPK signaling in RAW264.7 cells
Keywords: NFKB; PTERC-T; RANKL; Osteoclastogenesis; MAPK; NFκB;
The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration
Keywords: NFKB; 7TM; seven transmembrane; ADGR; adhesion G protein-coupled receptor; ADGRG2; adhesion G protein-coupled receptor subfamily G member 2; DNM2; dynamin 2; GAIN; GPCR Autoproteolysis Inducing; GPCR; G protein-coupled receptor; GPS; GPCR Proteolytic Site; GSHR
NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth
Keywords: NFKB; mTOR; Glut3; NFκB; Aerobic glycolysis; Tumorigenesis;
Jararhagin-induced mechanical hyperalgesia depends on TNF-α, IL-1β and NFκB in mice
Keywords: NFKB; Bothrops jararaca; Jararhagin; Metalloprotease; Cytokines; Hyperalgesia; NFκB;
Protective role of naringin against cisplatin induced oxidative stress, inflammatory response and apoptosis in rat striatum via suppressing ROS-mediated NF-κB and P53 signaling pathways
Keywords: NFKB; CAT; catalase; DNPH; dinithrophenylhydrazine; DCHF-DA; 2â²,7â²-dichlorofluorescein diacetate; GPx; glutathione peroxidase; MDA; malondialdehyde; NFκB; nuclear factor κB; PCO; protein carbonyls; qPCR; quantitative polymerase chain reaction; ROS; reacti
Promyelocytic leukemia protein induces arsenic trioxide resistance through regulation of aldehyde dehydrogenase 3 family member A1 in hepatocellular carcinoma
Keywords: NFKB; HCC; hepatocellular carcinoma; ATO; arsenic trioxide; APL; acute promyelocytic leukemia; PML; promyelocytic leukemia protein; RARα; retinoic acid receptor α; ALDH3A1; aldehyde dehydrogenase 3 family member A1; qRT-PCR; quantitative real-time reverse tra
Remote Ischemic Preconditioning for Kidney Protection: GSK3β-Centric Insights Into the Mechanism of Action
Keywords: NFKB; Acute kidney injury (AKI); remote ischemic preconditioning (IPC); limb IPC; ischemia/reperfusion; glycogen synthase kinase 3β (GSK3β); NFκB; Nrf2; inflammation; mitochondria permeability transition (MPT); lithium; renal protection; review;
MAPK signaling downstream to TLR4 contributes to paclitaxel-induced peripheral neuropathy
Keywords: NFKB; Dorsal root ganglion; Spinal dorsal horn; Chemotherapy; ERK1/2; P38; NFκB;
Vibrio cholerae porin OmpU induces LPS tolerance by attenuating TLR-mediated signaling
Keywords: NFKB; CCL; cysteine cysteine ligand; CXCR; cysteine-x-cysteine receptor; ELISA; enzyme linked immunosorbent assay; IL; interleukin; IRAK; interleukin-1 receptor associated kinase; LPS; lipopolysaccharide; MKP-1; MAPK phosphatase 1; MyD88; myeloid differentiatio
Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer
Keywords: NFKB; Apoptosis; SUM149; Antioxidant; XIAP; NFκB; ALDH;
Sp1 transcription factor: A long-standing target in cancer chemotherapy
Keywords: NFKB; Anticancer drugs; Prognosis; Sp1; Sp3; Transcription factors; Targeted therapy; AMPKα; AMP-activated protein kinase alpha catalytic subunit; Bcl-2; B cell/lymphoma 2; Bcl-w; member of the Bcl-2 family; Bid; BH3 interacting domain death agonist; CDK; cycl
Mechanical stretch endows mesenchymal stem cells stronger angiogenic and anti-apoptotic capacities via NFκB activation
Keywords: NFKB; Mechanical stretch; Mesenchymal stem cells; Angiogenesis; Apoptosis; NFκB;
The PGC-1 coactivators promote an anti-inflammatory environment in skeletal muscle in vivo
Keywords: NFKB; Inflammation; PGC-1; Skeletal muscle; Metabolism; Mitochondria; IL; interleukin; LPS; lipopolysaccharide; MCKα/β; muscle-specific PGC-1α/β transgenic mice; NFκB; nuclear factor κB; PGC-1; peroxisome proliferator-activated receptor γ coactivator 1;
Induction of S100A4 in periodontal ligament cells enhances osteoclast formation
Keywords: NFKB; S100A4; Periodontal ligament cells; Osteoclastogenesis; Inflammation; NFκB;
Acrylamide induces mitochondrial dysfunction and apoptosis in BV-2 microglial cells
Keywords: NFKB; ACR; acrylamide; DAPI; 4â²,6-diamidino-2-phenylindole; AO/EB; acridine orange/ethidium bromide; NAC; N-acetyl-L-cysteine; OCR; oxygen consumption rate; ECAR; extracellular acidification rate; PDH; pyruvate dehydrogenase; JNK; c-Jun N-terminal kinases; PA
Molecular mechanisms of rosmarinic acid from Salvia miltiorrhiza in acute lymphoblastic leukemia cells
Keywords: NFKB; (ALL); acute lymphoblastic leukemia; MDR; multidrug resistance; ABC; ATP binding cassette; P-gp; P-glycoprotein; ROS; reactive oxygen species; H2DCF-DA; 2â²,7â²-dichlorofluorescin diacetate; DCF; 2â²,7â²-dichlorofluorescein; PARP; poly (ADP-ribose) po
Dual effects of the non-esterified fatty acid receptor 'GPR40' for human health
Keywords: NFKB; AA; arachidonic acids; ABCD; ABC transporters; BDNF; brain-derived neurotrophic factor; BKCa channels; Ca2+-activated K+ channels; cAMP; cyclic AMP; CO; carbon monoxide; CLA; conjugated linoleic acids; CNS; central nervous system; CoA; coenzyme A; CREB; c
Arsenic programmes cellular genomic-immunity through miR-2909 RNomics
Keywords: NFKB; miRNA; MicroRNA; PBMCs; Peripheral blood mononuclear cells; CYLD; Cylindromatosis; KLF4; Kruppel-like factor4; NFκB; Nuclear factor kappa B; FCS; Foetal Calf Serum; As; Arsenic; IFNβ; Interferon beta; APOBEC3G; Apolipoprotein B mRNA-editing, enzyme-cata
Unsaponifiable fraction from extra virgin olive oil inhibits the inflammatory response in LPS-activated murine macrophages
Keywords: NFKB; Extra virgin olive oil; Unsaponifiable fraction; LPS-stimulated macrophages; ROS; NFκB; MAPK;
NFkappaB activation is essential for miR-21 induction by TGFβ1 in high glucose conditions
Keywords: NFKB; MicroRNA; miR-21; Diabetic wound healing; TGFβ1; NFκB;
Epicatechin attenuates atherosclerosis and exerts anti-inflammatory effects on diet-induced human-CRP and NFκB in vivo
Keywords: NFKB; Atherosclerosis; CRP; Epicatechin; Inflammation; NFκB; Polyphenol; human-CRP; human C-reactive protein; CVD; cardiovascular disease; E3L; ApoE*3-Leiden; HC; high-cholesterol group; HCE; high-cholesterol + epicatechin group; HCA; high-cholesterol + at
Rad GTPase inhibits the NFκB pathway through interacting with RelA/p65 to impede its DNA binding and target gene transactivation
Keywords: NFKB; Cavβ; calcium channel, voltage-dependent, beta subunit; CaM; calmodulin; EMSA; electrophoretic mobility shift assay; Gem; GTP binding protein overexpressed in skeletal muscle; Gmip; Gem interacting protein; GST; glutathione S-transferase; IκB; inhibitor
Involvement of NFκB in the antirheumatic potential of Chenopodium album L., aerial parts extracts
Keywords: NFKB; Chenopodium album; DPPH; Nitric oxide; Complete Freund׳s adjuvant; NFκB; Immunohistochemistry;
Betaglycan blocks metastatic behaviors in human granulosa cell tumors by suppressing NFκB-mediated induction of MMP2
Keywords: NFKB; AGCT; adult-type granulosa cell tumor; ECM; extracellular matrix; GCT; granulosa cell tumors; MMPs; matrix metalloproteinases; NFκB; nuclear factor kappa-B; qRT-PCR; quantitative real-time reverse transcriptase PCR; SFM; serum-free media; TGFβ; transfor
Cyclic phosphatidic acid and lysophosphatidic acid induce hyaluronic acid synthesis via CREB transcription factor regulation in human skin fibroblasts
Keywords: NFKB; BSA; bovine serum albumin; 2ccPA; 2-carba-cPA; ChIP; chromatin immunoprecipitation; CMF-PBS; calcium- and magnesium-free PBS; CRE; cyclic adenosine monophosphate response element; cPA; cyclic phosphatidic acid; CREB; CRE binding protein; ERK; extracellula
Elevated A20 contributes to age-dependent macrophage dysfunction in the lungs
Keywords: NFKB; ADMD; age-dependent macrophage dysfunction; BALF; bronchoalveolar lavage fluid; BSA; bovine serum albumin; DAPI; 4â², 6-diamidino-2-phenylindole; DMEM; Dulbecco's modified Eagle medium; GST; glutathione S-transferase; H&E; hematoxylin & eosin; IL; interl
TOP 1 and 2, polysaccharides from Taraxacum officinale, inhibit NFκB-mediated inflammation and accelerate Nrf2-induced antioxidative potential through the modulation of PI3K-Akt signaling pathway in RAW 264.7 cells
Keywords: NFKB; Taraxacum officinale polysaccharide; Anti-inflammatory; NFκB; Antioxidative; Nrf2; PI3KAkt;