دانلود مقالات ISI درباره Ngs + ترجمه فارسی

A comparison of 454 sequencing and clonal sequencing for the characterization of hepatitis C virus NS3 variants

Keywords: APD; average pairwise distance; HCV; hepatitis C virus; IQR; interquartile range; NGS; next-generation sequencing; NJ; Neighbor-Joining; NSE; normalized Shannon entropy; SRA; Sequence Read Archive database; SD; standard deviation; RAVs; resistance-associa

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Genomic characterization of Italian Clostridium botulinum group I strains

Keywords: BoNT; botulinum neurotoxin (protein); bont; botulinum neuro-toxin (gene); kb; kilobase; Mb; megabase; bp; base pairs; FGI; flagellar glycosylation island; MLST; MultiLocus Sequence Typing; MLVA; Multiple Loci Variable-number-tandem-repeat Analysis; NGS; N

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

RNA-Seq SSRs and small RNA-Seq SSRs: New approaches in cancer biomarker discovery

Keywords: BPC; Benign pancreatic cancer; CNVs; Copy number variations; DE; Differentially expressed; ESTs; Expressed sequence tags; ncRNAs; Non-coding RNAs; NGS; Next generation sequencing; PBMCs; Peripheral blood mononuclear cells; PC; Pancreatic cancer; RNA-seq;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The protein tyrosine phosphatase interacting protein 51 (PTPIP51) is required for the differentiation of photoreceptors

Keywords: ACs; amacrine cells; BCs; bipolar cells; div; days in vitro; eGFP; enhanced green fluorescent protein; GCL; ganglion cell layer; GS; Glutamine Synthetase; HCs; horizontal cells; INL; inner nuclear layer; ISH; in situ hybridization; MGCs; Müller glial cel

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

A potential anti-allodynic mechanism of GDNF following L5 spinal nerve ligation; Mitigation of NPY up-regulation in the touch sense pathway

Keywords: ANOVA; analysis of variance; DRG; dorsal root ganglion; EDTA; ethylenediaminetetraacetic acid; GDNF; glial cell line-derived neurotrophic factor; GN; gracile nucleus; ISHH; in situ hybridization histochemistry; L5; 5th lumbar; NGS; normal goat serum; NPY;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Impact of three Illumina library construction methods on GC bias and HLA genotype calling

Keywords: HLA genotyping; NGS; Transposase; Illumina Nextera; GC bias

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Dietary saponins from four popular herbal tea exert prebiotic-like effects on gut microbiota in C57BL/6 mice

Keywords: Gut microbiota; Herbal saponins; ERIC-PCR; Prebiotic-like effects; D0; day 0; D5; day 5; D10; day 10; D15; day 15; EDTA; ethylenediaminetetraacetic acid; ERIC; enterobacterial repetitive intergenic consensus; GpS; Gynostemma pentaphyllum saponins; GS; gin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

T-cell clonality assessment by next-generation sequencing improves detection sensitivity in mycosis fungoides

Keywords: cutaneous T-cell lymphoma; molecular diagnostics; mycosis fungoides; next-generation sequencing; T-cell clonality; T-cell receptor rearrangement; CE; capillary electrophoresis; CTCL; cutaneous T-cell lymphoma; MF; mycosis fungoides; NGS; next-generation s

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

IL-15Rα deficiency in skeletal muscle alters respiratory function and the proteome of mitochondrial subpopulations independent of changes to the mitochondrial genome

Keywords: Myokine; Mitochondrial subpopulations; Mitochondrial genome; NGS; Il-15; IL-15Rα;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Proteomic analysis of the crayfish gastrolith chitinous extracellular matrix reveals putative protein complexes and a central role for GAP 65

Keywords: ACC; amorphous calcium carbonate; CqCBP; C. quadricarinatus chitin-binding protein; CqCc1; C. quadricarinatus cryptocyanin 1; GFE; gastrolith-forming epithelium; GMPs; gastrolith matrix proteins; LPS-BP; lipopolysaccharide and beta-1,3-glucan-binding prot

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Mutational profiling in patients with MDS: Ready for every-day use in the clinic?

Keywords: myelodysplastic syndrome (MDS); mutations; amplicon deep-sequencing; next-generation sequencing; NGS; diagnostic algorithm

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of new SNPs in native South American populations by resequencing the Y chromosome

Keywords: Y chromosome; Y-SNPs; NGS; South America; Ecuador; Kichwa;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA dynamics during human embryonic stem cell differentiation to pancreatic endoderm

Keywords: hESC, human embryonic stem cells; miRNA, microRNA; NGS, Next Generation SequencingmiRNA; NGS; hESC; Pancreatic endoderm

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Differential expression of polycytosine-binding protein isoforms in adrenal gland, locus coeruleus and midbrain

Keywords: ENA; European Nucleotide Archive; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; KH domain; hnRNP K homology domain; NGS; normal goat serum; PBS; phosphate-buffered saline; PBS-Tx; Triton-X-100 dissolved in PBS; PCBP; polycytosine-binding prot

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

5-HT1B autoreceptors differentially modulate the expression of conditioned fear in a circuit-specific manner

Keywords: 1BKO; 5-HT1B receptor constitutive knockout mouse; AAV; adeno-associated virus; CAV; canine adenovirus; DIO; double-floxed inverted open reading frame; DRN; dorsal raphe nucleus; HA; hemagglutinin; HSV; herpes simplex virus; NGS; normal goat serum; ORF; o

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

MethodFast-Suppressor Screening for New Components in Protein Trafficking, Organelle Biogenesis and Silencing Pathway in Arabidopsis thaliana Using DEX-Inducible FREE1-RNAi Plants

Keywords: Suppressors; FREE1; Endomembrane trafficking; Arabidopsis; NGS; AFE; allele frequency estimation; DEX; dexamethasone; ESCRT; endosomal sorting complex required for transport; FREE1; FYVE domain protein required for endosomal sorting 1; MVB; multivesicular

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Functional genomic screening approaches in mechanistic toxicology and potential future applications of CRISPR-Cas9

Keywords: 3-BrPA; 3 bromopyruvate; AOP; adverse outcome pathway; ARF4; ADP-ribosylation factor 4; BFA; brefeldin A; BT; 1,2,4-benzenetriol; CML; chronic myeloid leukemia; COSMID; CRISPR off-target sites with mismatches, insertions, and deletions; CRISPR-Cas9; clust

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

The L-type voltage-gated calcium channel modulates microglial pro-inflammatory activity

Keywords: [Ca2+]i; intracellular calcium concentration; DAB; diaminobenzidine; DG; dentate gyrus; FBS; fetal bovine serum; GFAP; glial fibrillary acidic protein; IB4; isolectin B4; IFNγ; interferon-gamma; IL-1β; interleukin-1β; KW; Kruskal-Wallis; LPS; lipopol

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Advances in DNA sequencing technologies for high resolution HLA typing

Keywords: HLA typing; DNA sequence-based HLA typing (SBT); NGS; New alleles; Sanger sequencing; MiSeq; PacBio;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms

Keywords: BRCA1; Breast cancer; Classification; Copy number aberration profiles; aCGH; array Comparative Genomic Hybridization; BAC; Bacterial Artificial Chromosome; BAC32K; Bacterial Artificial Chromosome aCGH, 32K platform; BAC3K; Bacterial Artificial Chromosome

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

New insights into the wheat chromosome 4D structure and virtual gene order, revealed by survey pyrosequencing

Keywords: Bd; Brachypodium distachyon; CDS; coding DNA sequences; dN/dS; non-synonymous-to-synonymous substitutions; EST; expressed sequence tag; ISBP; insertion site-based polymorphism; IWGSC; International Wheat Genome Sequencing Consortium; LMP; long mate pair;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

The variation game: Cracking complex genetic disorders with NGS and omics data

Keywords: Complex disease; NGS; Next generation sequencing; Omics; Interactome; Variation; SNV; SNP; CNV; Alternative splicing

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Ethanol deregulates Mecp2/MeCP2 in differentiating neural stem cells via interplay between 5-methylcytosine and 5-hydroxymethylcytosine at the Mecp2 regulatory elements

Keywords: 5hmC; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; bFGF; basic fibroblast growth factor; Ct; threshold cycle values; DAPI; 4′,6-diamidino-2-phenylindole; D; day; DMEM/F12; Dulbecco's Modified Eagle Medium: Nutrient Mixture F-12; E; embryonic day; EDT

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Droplet digital polymerase chain reaction assay for screening of ESR1 mutations in 325 breast cancer specimens

Keywords: LBD; ligand-binding domain; ERα; estrogen receptor α; NGS; next generation sequencing; ER+; ER-positive; AIs; aromatase inhibitors; MBC; metastatic breast cancer; ddPCR; droplet digital polymerase chain reaction; FFPE; formalin-fixed paraffin embedded;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Rat dams exposed repeatedly to a daily brief separation from the pups exhibit increased maternal behavior, decreased anxiety and altered levels of receptors for estrogens (ERα, ERβ), oxytocin and serotonin (5-HT1A) in their brain

Keywords: Maternal behavior; Anxiety; Estrogen receptors; Oxytocin receptors; Serotonergic system; Prefrontal cortex; Hippocampus; Amygdala; Medial preoptic area; Nucleus accumbens; 5-HT1AR; serotonin receptor type 1A; ANOVA; analysis of variance; BLA; basolateral

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Systematic analysis of CRISPR-Cas9 mismatch tolerance reveals low levels of off-target activity

Keywords: CRISPR; clustered regularly interspaced palindromic repeats; Cas9; CRISPR associated protein 9; crRNA; CRISPR RNA; tracrRNA; trans-activating CRISPR RNA; PAM; protospacer adjacent motif; sgRNA; single guide RNA; NGS; next generation sequencing; PSC; pluri

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2015 سفارش ترجمه

Peanut oral immunotherapy transiently expands circulating Ara h 2-specific B cells with a homologous repertoire in unrelated subjects

Keywords: Immunotherapy; antigen-specific B cells; peanut allergy; food allergy; antibody repertoire; APC; Allophycocyanin; BCR; B-cell receptor; CDR; Complementarity-determining region; NGS; Next-generation sequencing; OIT; Oral immunotherapy; PNOIT; Peanut oral i

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2015 سفارش ترجمه

An overview of microRNAs

Keywords: RISC; RNA induced silencing complex; MCM7; Minichromosome maintenance protein 7; DGCR8; DiGeorge syndrome critical region 8; TRBP; TAR RNA binding protein; NGS; Next generation sequencing; C3PO; Component 3 promoter of RISC; TNRC6; Trinucleotide repeat co

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

Transcriptomic and proteomic analyses of Amphiura filiformis arm tissue-undergoing regeneration

Keywords: NGS; next generation sequencing; 1DE; first dimensional gel electrophoresis; 2DE; two-dimensional gel electrophoresis; FTMS; Fourier transform mass spectrometer; ITMSMS; ion trap tandem mass spectrometer; dpa; day(s) post amputation; Transcriptomics; Prot

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2015 سفارش ترجمه

Involvement of p38 MAPK activation mediated through AT1 receptors on spinal astrocytes and neurons in angiotensin II- and III-induced nociceptive behavior in mice

Keywords: Angiotensin II; Angiotensin III; AT1 receptors; Nociceptive behavior; p38 MAPK; Astrocyte; Neuron; Intrathecal administration; Mice; Ang; angiotensin; AT1; Ang II type 1; AT2; Ang II type 2; i.t.; intrathecal; MAPK; mitogen-activated protein kinase; ACE;

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2015 سفارش ترجمه

Disruption of the mevalonate pathway induces dNTP depletion and DNA damage

Keywords: ACN; acetonitrile; BrdU; 5-bromo-2′-deoxyuridine; DMAPP; dimethylallyl diphosphate; dNs; deoxyribonucleosides; dNTP; deoxyribonucleoside triphosphate; E2F; E2 transcription factor; Fmev; 6-fluoromevalonate; IPP; isopentenyl diphosphate; HU; hydroxyurea;

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2015 سفارش ترجمه

Sequential combination of karyotyping and RNA-sequencing in the search for cancer-specific fusion genes

Keywords: FISH; fluorescence in situ hybridization; NGS; next generation sequencing; RNA-Seq; RNA sequencing; WES; whole exome sequencing; WGS; whole genome sequencing; Karyotyping; RNA-sequencing; Cancer-specific fusion genes;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Rovac is the possible ancestor of the Russian lapinized vaccines LK-VNIVViM and CS strains but not the Chinese strain (C-strain) vaccine against classical swine fever

Keywords: Vaccine; Evolution; CSFV; Molecular phylogeny; C-strain; NGS;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Next-generation sequencing (NGS) as a fast molecular diagnosis tool for left ventricular noncompaction in an infant with compound mutations in the MYBPC3 gene

Keywords: MYBPC3; Cardiomyopathy; Left ventricular noncompaction; NGS; Molecular diagnosis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

HLA-C locus allelic dropout in Sanger sequence-based typing due to intronic single nucleotide polymorphism

Keywords: CDS; Coding Sequence; SBT; Sequence Based Typing; dNTP; Deoxynucleotide Triphosphate; PCR; Polymerase Chain Reaction; HLA; Human Leukocyte Antigen; SSP; Sequence Specific Primer; LB; Luria Broth; WHO; World Health Organization; SNP; Single Nucleotide Poly

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Validation of ambiguous MLPA results by targeted next-generation sequencing discloses a nonsense mutation in the DMD gene

Keywords: DMD; Duchenne muscular dystrophy; MLPA; Multiplex ligation-dependent probe amplification; IDP; a Ready-to-Use AmpliSeq™ Inherited Disease Panel; PGM; Ion Torrent Personal Genome Machine™; RPR; relative peak ratio; NGS; next-generation sequencing; Duch

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

A preliminary Quality Control (QC) for next generation sequencing (NGS) library evaluation turns out to be a very useful tool for a rapid detection of BRCA1/2 deleterious mutations

Keywords: NGS, next generation sequencing; GS, Gene Scan; QC, Quality Control; MPS, massive parallel sequencing; MLPA, multiplex ligation-dependent probe amplification; MAQ, multiplex amplicon quantificationBRCA1; BRCA2; Frameshift mutations; NGS; Breast cancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Neuropharmacology and analgesiaAntinociceptive effect of botulinum toxin type A on experimental abdominal pain

Keywords: BTX-A; botulinum toxin type A; CNS; central nervous system; CSF; cerebrospinal fluid; GABA; γ-aminobutyric acid; i.c.; intracisternal; i.col.; intracolonic; i.p.; intraperitoneal; i.t.; intrathecal; NGS; normal goat serum; NSAIDs; Non-steroidal anti-infl

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Mitochondrial myopathy, lactic acidosis, and sideroblastic anemia (MLASA) plus associated with a novel de novo mutation (m.8969G>A) in the mitochondrial encoded ATP6 gene

Keywords: MLASA; mitochondrial myopathy, lactic acidosis, and sideroblastic anemia; ETC; electron transport chain; CS; citrate synthase; OCR; oxygen consumption rate; OSR; oligomycin sensitive respiration; RC; respiratory capacity; SRC; spare respiratory capacity;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Hyperhomocysteinemia: Related genetic diseases and congenital defects, abnormal DNA methylation and newborn screening issues

Keywords: AHCY; adenosylhomocysteinase; BHMT; betaine-homocysteine methyl-transferase; Cbl-C; cobalamin C; CHD; congenital heart defects; CTH; cystathionine-γ-lyase; CBS; cystathionine-β-synthase; DS; Down syndrome; hHcy; hyperhomocysteinemia; Hcy; homocysteine

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Improving the quality of protein identification in non-model species. Characterization of Quercus ilex seed and Pinus radiata needle proteomes by using SEQUEST and custom databases

Keywords: Protein identification; Custom databases; Non-model species; SEQUEST; ESTs; NGS

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Comparison of targeted next-generation sequencing with conventional sequencing for predicting the responsiveness to epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) therapy in never-smokers with lung adenocarcinoma

Keywords: NGS; NSCLC; EGFR; PIK3CA;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Targeted next-generation sequencing: A novel diagnostic tool for primary immunodeficiencies

Keywords: Primary immunodeficiency; diagnosis; genetics; next-generation sequencing; ALPS; Autoimmune lymphoproliferative syndrome; CID; Combined immunodeficiency; HLH; Hemophagocytic lymphohistiocytosis; IUIS; International Union of Immunodeficiency Societies; NGS

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Fundamentals of vitamin D hormone-regulated gene expression

Keywords: VDR; vitamin D receptor; ChIP; chromatin immunoprecipitation; ChIP-chip; ChIP coupled to tiled microarrays; ChIP-seq; ChIP coupled to deep sequencing methods; VDRE; vitamin D response element; NGS; Next Generation Sequencing; RXR; retinoid X receptor; VDI

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

My-Forensic-Loci-queries (MyFLq) framework for analysis of forensic STR data generated by massive parallel sequencing

Keywords: Illumina; MiSeq; STR; Forensic loci; MPS; NGS;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Detection and genetic characterisation of a novel mycovirus in Hymenoscyphus fraxineus, the causal agent of ash dieback

Keywords: NGS; Mitovirus; ssRNA virus; Biological control; RNA virus detection; Actin;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Hereditary motor and sensory neuropathies or Charcot-Marie-Tooth diseases: An update

Keywords: HMSN; Charcot-Marie-Tooth disease (CMT); AR CMT1; AR CMT2; NGS; PXT3003 trial;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

R-Ras contributes to LTP and contextual discrimination

Keywords: AAV; adeno-associated viruses; ACSF; artificial cerebrospinal fluid; HFS-LTP; high-frequency stimulation long-term potentiation; LTD; long-term depression; PB; phosphate buffer; PBS; phosphate-buffered saline; NGS; normal goat serum; PFA; paraformaldehyde

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The intracellular inhibition of HCV replication represents a novel mechanism of action by the innate immune Lactoferrin protein

Keywords: HCV; Hepatitis C virus; hLF; human Lactoferrin; LF; Lactoferrin; HIV; human immunodeficiency virus; HSV1; herpes simplex virus type 1; CMV; cytomegalovirus; RDRP; RNA-dependent RNA polymerase; NGS; normal goat serum; WGA; wheat germ agglutinin; IPTG; isop

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Insight into small RNA abundance and expression in high- and low-temperature stress response using deep sequencing in Arabidopsis

Keywords: NGS; miRNAs; Small RNAs; Temperature stress; Arabidopsis; AGO4; Argonaute 4; AGO6; Argonaute 6; ATGB2; GTP-binding protein 2; COR15A; cold-regulated 15A; COR413; cold-regulated 413; COR47; cold-regulated 47; COR47; cold-regulated 47; DCL1; DICER-like 1; D

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه