دانلود مقالات ISI درباره دامنه درون سلولی Notch + ترجمه فارسی

جنبه های بالینی و تجربی سیگنال گیرنده ی رگه ای: سندرم حجت چنی و اختلالات مرتبط با آن

Clinical and experimental aspects of notch receptor signaling: Hajdu-Cheney syndrome and related disorders

Keywords: دامنه درون سلولی Notch; ANK; ankyrin; CADASIL; cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy; CSL; CBF1, Suppressor of Hairless Lag 1; CHYS1; chondroitin sulfate synthase; Dll; Delta-like; EGF; epidermal growth factor; EOGT; EGF domai

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

تهویه ایسکمیک راه دور از طریق افزایش فعالیت سیگنالینگ و ترویج آرتریوژنز در مغز موش صحرایی ایسکمی

Limb remote ischemic conditioning increases Notch signaling activity and promotes arteriogenesis in the ischemic rat brain

Keywords: دامنه درون سلولی Notch; LRIC; limb remote ischemic conditioning; NICD; Notch intracellular domain; α-SMA; α-smooth muscle actin; MCAO; middle cerebral artery occlusion; CBF; cerebral blood flow; PreC; ischemic pre-conditioning; PerC; ischemic per-conditioning; PostC; ischemic

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

هدف قرار دادن مسیرهای مولکولی در سلول های بنیادی سرطانی با ترکیبات طبیعی زیست فعال

Targeting molecular pathways in cancer stem cells by natural bioactive compounds

Keywords: دامنه درون سلولی Notch; 5-FU; 5-Fluorouracil; ABCB5; ATP-binding cassette sub-family B member 5; ABCC2; ATP-binding cassette sub-family C member 2; ABCG2; ATP-binding cassette sub-family G member 2; ACs; Anthocyanins; ALDH; aldehyde dehydrogenase; AML; acute myeloid leukemia; AP

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

القاء دائمی تمایز سلولهای جام در مسیرهای هوایی: رویکردهای درمانی

Persistent induction of goblet cell differentiation in the airways: Therapeutic approaches

Keywords: دامنه درون سلولی Notch; cAMP; Cyclic Adenosine Monophosphate; COPD; Chronic Obstructive Pulmonary Disease; CCSP; Club Cell Secretory Protein; CF; Cystic Fibrosis; EGFR; Epidermal Growth Factor Receptor; EMT; Epithelial to Mesenchymal Transition; ERK; Extracellular Signal-Regulat

دانلود رایگان متن کامل مقاله ISI 74 صفحه سال انتشار : 2018 سفارش ترجمه

سیگنالینگ آنژیوژنیک و مقاومت دارویی تومور

Redundant angiogenic signaling and tumor drug resistance

Keywords: دامنه درون سلولی Notch; ALK1; activin receptor-like kinase1; ANG/Ang; angiopoietin; Bcl-xL; b-cell lymphoma-extra large; BM; bone marrow; BMDCs; bone marrow derived cells; BMP; bone morphogenetic protein; Bv8; bombina variagata peptide 8; CAFs; cancer/carcinoma associated fibrob

دانلود رایگان متن کامل مقاله ISI 99 صفحه سال انتشار : 2018 سفارش ترجمه

بررسی اجمالی از مطالعات پیش از بالینی و بالینی که هدف آنژیوژنز در آدنوکارسینوم مدول پانکراس است

Overview of pre-clinical and clinical studies targeting angiogenesis in pancreatic ductal adenocarcinoma

Keywords: دامنه درون سلولی Notch; Pancreatic cancer; Angiogenesis; Vascular endothelial growth factor (VEGF); ANGPT; angiopoietin; BRAF; serine/threonine-protein kinase B-raf; CAF; cancer associated fibroblast; Cdkn2a; cyclin-dependent kinase inhibitor 2A; CI; confidence interval; CSF1R;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

مکانیزم های مولکولی کارسینوم سلول سنگفرشی هوا مری با اتانول

Molecular mechanisms of ethanol-associated oro-esophageal squamous cell carcinoma

Keywords: دامنه درون سلولی Notch; 4NQO; 4-nitroquinoline 1-oxide; ADH; alcohol dehydrogenase; ALDH; acetaldehyde dehydrogenase; CYP2E1; cytochrome P450 2E1; Edh; EH-domain containing gene; ELOVL; very long chain fatty acid elongase; GPCRs; G-protein coupled receptors; HNE; 4-hydroxynonena

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

قطبی شدن و عملکرد ماکروفاژ با تاکید بر نقش های در حال تحول از تنظیم هماهنگ مسیرهای سیگنالینگ سلولی

Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways

Keywords: دامنه درون سلولی Notch; KCs; kupffer cells; JNKs; C-Jun N-terminal kinases; MAPKs; mitogen-activated protein kinases; CCR2; C-C motif chemokine receptor 2; ATMs; Adipose tissue macrophages; HFD; high-fat diet; MLK3; mixed-lineage kinase 3; PPAR; peroxisome proliferator-activat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

فاکتور رشد مرتبط بافت یک هدف سیگنالینگ نکته در سلول های خطوط استئوآرتریت است

Connective Tissue Growth Factor is a Target of Notch Signaling in Cells of the Osteoblastic Lineage

Keywords: دامنه درون سلولی Notch; ATCC; American Type Culture Collection; Bglap; bone gamma carboxyglutamate protein; BMP; bone morphogenetic protein; BSA; bovine serum albumin; CCN; Cyr61, connective tissue growth factor and Nov; CMV; cytomegalovirus; Col2.3; 2.3 kb fragment of Col1a1;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

طرفهای تاریک آمیلوئید در پاتوژنز بیماری آلزایمر

The dark sides of amyloid in Alzheimer's disease pathogenesis

Keywords: دامنه درون سلولی Notch; Aβ; amyloid β protein; NFT; neurofibrillary tangles; APP; amyloid precursor protein; PSs; presenilins; NICD; Notch intracellular domain; mTOR; mammalian Target of Rapamycin; PP2A; protein phosphatase 2; GSK-3; glycogen synthase kinase-3; CTFS; cytosol-s

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Successful liver-directed gene delivery by ERCP-guided hydrodynamic injection (with videos)

Keywords: دامنه درون سلولی Notch; AKT; protein kinase B; CBD; common bile duct; CHD; common hepatic duct; NICD; notch intracellular domain; PCR; polymerase chain reaction; CMV-SB; pCytomegalovirus Sleep Beauty;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

The Notch pathway inhibitor stapled α-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma

Keywords: دامنه درون سلولی Notch; Allergic asthma; Notch signaling; Gata3; TH2 immunity; house dust mite; recombination signal-binding protein for IgJκ region; stapled α-helical peptide derived from mastermind-like 1; BAL; Bronchoalveolar lavage; BHR; Bronchial hyperreactivity; DC; De

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Hypoxia-stressed cardiomyocytes promote early cardiac differentiation of cardiac stem cells through HIF-1α/Jagged1/Notch1 signaling

Keywords: دامنه درون سلولی Notch; BMSCs; bone marrow stem cells; BrdU; 5-bromo-2′-deoxyuridine; CMs; cardiomyocytes; CSCs; cardiac stem cells; DAPI; 4′,6-diamidino-2-phenylindole; DMSO; dimethyl sulfoxide; ERK; extracellular signal-regulated kinase; FBS; fetal bovine serum; FITC; fluo

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Maternal Consumption of High-fat Diet in Mice Alters Hypothalamic Notch Pathway, NPY Cell Population and Food Intake in Offspring

Keywords: دامنه درون سلولی Notch; ARC; arcuate nucleus; Ascl1; achaete-scute homolog 1; bHLH; basic helix-loop-helix; BMP; bone morphogenetic protein; BrDU; 5-bromo-2′-deoxyuridine; BSA; bovine serum albumin; BW; body weight; Ct; comparative threshold cycle; Cy3; cyanine 3; DAB; 3,3′-

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Natural and synthetic polymers/bioceramics/bioactive compounds-mediated cell signalling in bone tissue engineering

Keywords: دامنه درون سلولی Notch; ALP; alkaline phosphatase; ANG; angiogenin; AuNPs; gold nanoparticles; BMP; bone morphogenetic protein; BSP; bone sialoprotein; BTE; bone tissue engineering; COL1; collagen type 1; CSL; CBF1/Su(H)/Lag-1 protein; ERK; extracellular signal-regulated kinase;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

In silico analysis, seasonal variation and gonadotropic regulation of jag1 and its receptor notch1 in testis of spotted snakehead Channa punctatus

Keywords: دامنه درون سلولی Notch; DSL; Delta, Serrate and LAG2; EGF; Epidermal growth factor; hCG; Human chorionic gonadotropin; ORF; Open reading frame; RT-PCR; Reverse transcription polymerase chain reaction; qPCR; Quantitative polymerase chain reaction; ANOVA; Analysis of variance; TMD

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of miR-363 protects cardiomyocytes against hypoxia-induced apoptosis through regulation of Notch signaling

Keywords: دامنه درون سلولی Notch; miRNAs; microRNAs; FBS; fetal bovine serum; RT-qPCR; real-time quantitative polymerase chain reaction; LDH; lactate dehydrogenase; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NICD; Notch intracellular domain; UTR; untranslated regio

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibition of Notch signalling has ability to alter the proximal and distal TCR signalling events in human CD3+ αβ T-cells

Keywords: دامنه درون سلولی Notch; TCR; T cell receptor; Dll; delta-like ligand; GSI-X; γ-secretase inhibitor; HES1; hairy enhancer of split1; IFN-γi; nterferon-γ; NICD; Notch intracellular domain; Jag; jagged; NRARP; Notch-regulated ankyrin repeat protein; αβ T cells; T cell anergy;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Inscuteable maintains type I neuroblast lineage identity via Numb/Notch signaling in the Drosophila larval brain

Keywords: دامنه درون سلولی Notch; Drosophila larval brain neuroblasts (NBs); Inscuteable (Insc); NB lineage maintenance; Type I and type II NBs; Numb/Notch signaling; Ase; Asense; Dpn; Deadpan; Erm; Earmuff; GMCs; ganglion mother cells; INPs; intermediate neural progenitors; Insc; Inscute

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Emerin suppresses Notch signaling by restricting the Notch intracellular domain to the nuclear membrane

Keywords: دامنه درون سلولی Notch; CSL; CBF1/suppressor hairless/Lag-1; NEXT; Notch1 extracellular truncation; NICD; Notch intracellular domain; ADAM; A disintegrin and metalloproteinase; CoA; Coactivators; CoR; Corepressors; PM; Plasma membrane; NE; Nuclear envelope; NGPS; Néstor-Guiller

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

The metalloproteinase ADAM10: A useful therapeutic target?

Keywords: دامنه درون سلولی Notch; APL; Acute Promyelocytic Leukemia; ADAM; A Disintegrin And Metalloproteinase; AP2; Adaptor Protein-2; AD; Alzheimer's Disease; Aβ; Amyloid beta; APP; Amyloid Precursor Protein; ACE; Angiotensin Converting Enzyme; APRIL; A Proliferation-Inducing Ligand; B

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2017 سفارش ترجمه

Redox signaling in the gastrointestinal tract

Keywords: دامنه درون سلولی Notch; HNE; 4-hydroxynonenal; 8-OHdG; 8-oxo-7,8-dihydro-2′-deoxyguanosine; AP-1; Activator protein 1; APC; Adenomatous polyposis coli; APE-1; Apurinic/apyrimidinic endonuclease 1; Math1; Atonal homolog 1; Bax; BCL2-associated X protein; β-TrCP; Beta-transduci

دانلود رایگان متن کامل مقاله ISI 150 صفحه سال انتشار : 2017 سفارش ترجمه

Stroma-induced Jagged1 expression drives PC3 prostate cancer cell migration; disparate effects of RIP-generated proteolytic fragments on cell behaviour and Notch signaling

Keywords: دامنه درون سلولی Notch; Invasion; Jagged1; Metastasis; Migration; Notch signaling; Prostate cancer; ADAM; A disintegrin and metalloproteinase; BMECs; bone marrow endothelial cells; BMS; bone marrow stroma; Dll; Delta-like ligand; FL-Jag; full-length Jagged; JCTF; Jagged1 C-termi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

DLL4+ dendritic cells: Key regulators of Notch Signaling in effector T cell responses

Keywords: دامنه درون سلولی Notch; APC; antigen presenting cell; CTL; cytotoxic T lymphocyte; DC; dendritic cell; cDC; conventional dendritic cell; pDC; plasmacytoid dendritic cell; CMP; common myeloid progenitor; HPC; hematopoietic progenitor cell; MDP; macrophage and DC progenitor; HSCT;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development

Keywords: دامنه درون سلولی Notch; BLPD; B-cell lymphoproliferative disease; EtOH; ethanol; HF; hair follicle; LICD; ligand intracellular domain; msx2LOF; Msx2-Cre+/tg-mediated loss of function; NICD; Notch intracellular domain; N1VG; hypomorphic Notch1 allele; PSmsx2LOF; Preselin1 and Pre

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Lack of galectin-3 increases Jagged1/Notch activation in bone marrow-derived dendritic cells and promotes dysregulation of T helper cell polarization

Keywords: دامنه درون سلولی Notch; Th; T helper; WT; wild-type; Lgals3−/−; galectin-3-deficient mice; BMDC; bone marrow-derived dendritic cell; DCs; dendritic cells; NICD; Notch intracellular domain; APC; antigen presenting cell; Treg; T regulatory cell; qPCR; quantitative polymerase c

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Cardiomyocyte Lineage Specification in Adult Human Cardiac Precursor Cells Via Modulation of Enhancer-Associated Long Noncoding RNA Expression

Keywords: دامنه درون سلولی Notch; cardiac precursor cells; differentiation; heart disease; lncRNAs; miRNAs; NOTCH; CARMEN; (CAR)diac (M)esoderm (E)nhancer-associated (N)oncoding RNA; CPC; cardiac precursor cell; DLL1; Delta-like1; GO; gene ontology; J1; Jagged1; lncRNA; long noncoding RNA

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

Clinical Application of Basic ScienceNotch signaling and new therapeutic options in liver disease

Keywords: دامنه درون سلولی Notch; Jag-1; Jagged-1; Dll; Delta-like; NICD; Notch intracellular domain; RBP-Jκ; recombination signal binding protein immunoglobulin kappa J; MAML1; mastermind-like 1; Hes1; hairy enhancer of split-1; Hey1; hairy enhancer of split-related with YRPW motif1; So

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Frequent mutations in NOTCH1 ligand-binding regions in Japanese oral squamous cell carcinoma

Keywords: دامنه درون سلولی Notch; OSCC; oral squamous cell carcinoma; HNSCC; head and neck squamous cell carcinoma; NECD; NOTCH extracellular domain; NICD; NOTCH intracellular domain; TALL; T-cell acute lymphoblastic leukemia; EGF; epidermal growth factor; T stage; tumor stage; N stage; l

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The Notch γ-secretase inhibitor ameliorates kidney fibrosis via inhibition of TGF-β/Smad2/3 signaling pathway activation

Keywords: دامنه درون سلولی Notch; Kidney fibrosis; Epithelial-to-mesenchymal transition; Fibroblast; Notch; TGF-β; DBZ; dibenzazepine; UUO; unilateral ureteral obstruction; NICD; Notch intracellular domain; ICN; intracellular domain of Notch; TECs; tubular epithelial cells; ECM; extracel

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Notch4 reveals a novel mechanism regulating Notch signal transduction

Keywords: دامنه درون سلولی Notch; ANK; ankyrin repeat; DSL; Delta, Serrate and Lag-2; JAG1; Jagged1; DLL1; Delta-like 1; DLL4; Delta-like 4; E; embryonic day; EC; extracellular domain; EGF; epidermal growth factor; ER; endoplasmic reticulum; ES; embryonic stem; HD; heterodimerisation doma

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

ADAM10 Regulates Notch Function in Intestinal Stem Cells of Mice

Keywords: دامنه درون سلولی Notch; CBC; Intestinal Epithelium; Development; Differentiation; ADAM10; A disintegrin and metalloproteinase domain-containing protein 10; CBCs; crypt-based columnar cells; Dll; Delta-like ligand; EGFP; enhanced green fluorescent protein; IP; intraperitoneally;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2014 سفارش ترجمه

Ferritin light chain interacts with PEN-2 and affects γ-secretase activity

Keywords: دامنه درون سلولی Notch; Aβ; β-amyloid; AD; Alzheimer's disease; APP; β-amyloid precursor protein; CTF; carboxyl-terminal fragment; FTH; ferritin heavy chain; FTL; ferritin light chain; HEK293Swe; HEK293 cells stably expressing human APP Swedish mutations; NICD; notch intracel

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Basic NeuroscienceAn improved cell-based method for determining the γ-secretase enzyme activity against both Notch and APP substrates

Keywords: دامنه درون سلولی Notch; GSI; γ-secretase inhibitor; GSM; γ-secretase modulator; NICD; Notch intracellular domain; β-Amyloid; Aβ; 2B; 7CHO-2B7; γ-Secretase; Notch; Aβ; Alzheimer's Disease; Modulator; NICD;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Notch ligand endocytosis: Mechanistic basis of signaling activity

Keywords: دامنه درون سلولی Notch; ADAM; a disintegrin and metalloprotease; AFM; atomic force microscopy; CSL; CBF1, Su(H), LAG-1; Dll; Delta-like; EDTA; ethylenediaminetetraacetic acid; GSI; γ-secretase inhibitor; HD; heterodimerization domain; LNRs; Lin12/Notch repeats; NECD; Notch extr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Notch Signaling Is Activated in Human Hepatocellular Carcinoma and Induces Tumor Formation in Mice

Keywords: دامنه درون سلولی Notch; Genetically Engineered Mouse Model; Notch Activation; Gene Expression Profiling; AFP; α-fetoprotein; GFP; green fluorescent protein; GSI; γ-secretase inhibitor; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; Igf2; insulin-like growth factor 2; I

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

hCLP46 regulates U937 cell proliferation via Notch signaling pathway

Keywords: دامنه درون سلولی Notch; hCLP46; human CAP10-like protein 46 kDa; Poglut; protein O-glucosyltransferase; Poglut1; protein O-glucosyltransferase1 (mammalian); CDKI; cyclin-dependent kinase inhibitor; CDKN1B (p27); cyclin-dependent kinase inhibitor 1B; RB; retinoblastoma; CSL; CBF

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Delta-like 1-Lysine613 regulates notch signaling

Keywords: دامنه درون سلولی Notch; Dll1; Delta-like 1; DSL; Delta/Serrate/Lag2; Notch-ICD; Notch intracellular domain; Notch-ECD; Notch extracellular domain; HES1; Hairy/enhancer of Split 1; HEY1; Hairy/enhancer of split related with YRPW motif protein 1; CSL; Suppressor of Hairless/Lag1;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Selective repression of Notch pathway target gene transcription

Keywords: دامنه درون سلولی Notch; CSL; Notch intracellular domain; Transcription; Development; Differentiation; Epigenetic

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Notch: Architect, Landscaper, and Guardian of the Intestine

Keywords: دامنه درون سلولی Notch; Intestine; Stem Cells; Homeostasis; Notch; Colon Cancer; AES; Amino terminal Enhancer of Split; AMP; adult midgut progenitor; bHLH; basic helix-loop-helix; CBC; columnar base cell; Dll; Delta-like ligand; EB; enteroblast; EC; enterocyte; EE; enteroendocri

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Presenilin mouse and zebrafish models for dementia: Focus on neurogenesis

Keywords: دامنه درون سلولی Notch; AD; Alzheimer's disease; PSEN; presenilin; APP; amyloid precursor protein; Aβ; β-amyloid; FAD; familial forms of AD; SVZ; subventricular zone; SGZ; subgranular zone; DG; dentate gyrus; NSCs; neural stem cells; DCX; doublecortin; NPC; neural progenitor c

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

Role of Notch and its oncogenic signaling crosstalk in breast cancer

Keywords: دامنه درون سلولی Notch; 4T1 cells; mouse mammary cancer cell line; ADAM; a disintegrin and metalloprotease; Akt; protein kinase B; ALDH; aldehyde dehydrogenase; ANK; ankyrin; Axin2; the Axin-related protein; BALB/c; an albino, laboratory-bred strain of the house mouse; Bcl-2; B-

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Notch signaling and Atoh1 expression during hair cell regeneration in the mouse utricle

Keywords: دامنه درون سلولی Notch; CSF; cerebrospinal fluid; GER; greater epithelial ridge; NICD; Notch intracellular domain; PBS; phosphate-buffered saline; PFA; paraformaldehyde; qRTPCR; quantitative real-time polymerase chain reaction;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Atonal Homolog 1 Is Required for Growth and Differentiation Effects of Notch/γ-Secretase Inhibitors on Normal and Cancerous Intestinal Epithelial Cells

Keywords: دامنه درون سلولی Notch; Biomarkers; Cell Fate Specification; Basic Helix-Loop-Helix Transcription Factor; Notch Intracellular Domain; APC; adenomatosis polyposis coli; ATOH1; atonal homolog 1; BrdU; bromodeoxyuridine; CRC; colorectal cancer; DAPT; N-[N-(3,5-difluorophenacetyl)-l

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2010 سفارش ترجمه

Attenuation of Notch signaling promotes the differentiation of neural progenitors into neurons in the hippocampal CA1 region after ischemic injury

Keywords: دامنه درون سلولی Notch; cerebral ischemia; γ-secretase; hippocampus; neurogenesis; regeneration; aCSF; artificial cerebrospinal fluid; APP; amyloid precursor protein; aSVZ; anterior subventricular zone; BrdU; bromodeoxyuridine; DCX; doublecortin; DLL4; delta-like protein 4; DMS

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Intestinal Deletion of Pofut1 in the Mouse Inactivates Notch Signaling and Causes Enterocolitis

Keywords: دامنه درون سلولی Notch; BSA; bovine serum albumin; CVA; crypt-villus axis; GALT; gut-associated lymphoid tissue; GSI; γ-secretase inhibitor; HES; hairy and enhancer of split; HRP; horseradish peroxidase; NICD; Notch intracellular domain; MLN; mesenteric lymph nodes; PCR; polyme

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2008 سفارش ترجمه

Neurosecretases provide strategies to treat sporadic and familial Alzheimer disorders

Keywords: دامنه درون سلولی Notch; ADAM; a disintegrin and metalloprotease; ACDL; acidic dileucine; ADDL; amyloid-β derived diffusible ligands; APP; amyloid precursor protein; Aph; anterior pharynx defective phenotype; APLP; APP-like protein; AICD; APP intracellular domain; AD; Alzheimer'

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2008 سفارش ترجمه

Fe65 does not stabilize AICD during activation of transcription in a luciferase assay

Keywords: دامنه درون سلولی Notch; Aβ; β-amyloid peptide; APP; amyloid precursor protein; AICD; APP intracellular domain; sαAPP; soluble α-amyloid precursor protein; BACE; β-site APP-cleaving enzyme; CHO; Chinese hamster ovary; CTF; C-terminal fragment of APP; DAPT; N-[N-(3,5-difluoro

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Zinc-induced downregulation of Notch signaling is associated with cytoplasmic retention of Notch1-IC and RBP-Jk via PI3k–Akt signaling pathway

Keywords: دامنه درون سلولی Notch; Notch intracellular domain; RBP-Jk; Zinc; Phosphatidylinositol 3-kinase; Akt; Cytoplasmic retention; Wortmannin; LY294002

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Matrix Metalloproteinase-9 Regulates MUC-2 Expression Through Its Effect on Goblet Cell Differentiation

Keywords: دامنه درون سلولی Notch; AB; Alcian Blue; CA; carbonic anhydrase; ECM; extracellular matrix; MMP; matrix metalloproteinases; NICD; Notch intracellular domain; PAS; periodic acid-Schiff stain; WT; wild type;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه