Keywords: 2-AA; 2-aminobenzoic acid; ABC; ammonium bicarbonate; ACN; acetonitrile; DHB; 2,5-dihydroxybenzoic acid; DTT; dithiothreitol; FA; formic acid; HILIC-FLD; hydrophilic interaction liquid chromatography-fluorescence detection; IAA; iodacetamide; MALDI; matri
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Keywords: Glucocorticoid; Non-genomic effect; Glucose uptake; C2C12 myotube; Contraction; Glut4 translocation; GCs; glucocorticoids; GRE; glucocorticoid response element; GR; glucocorticoid receptor; AMPK; 5â²-monophosphate (AMP)-activated protein kinase; CaMKII;
Keywords: FA; Ferulic acid; LZ; Ligustrazine; THP; Tetrahydropalmatine; GnRH; Gonadotropin-releasing hormone; FSH; Follicle-stimulating hormone; LH; Luteinizing hormone; E2; Estradiol; ER; Estrogen receptor; HSP90; Heat-shock protein 90; COX-2; Cycloxygenase-2; ERE
Keywords: Amylopectin; Amyloplast; Protein phosphorylation; Protein-protein interactions; Starch branching enzyme; Starch phosphorylase; Starch synthesis; ADP-Glc; ADP-glucose; aeâ; amylose extender; AGPase; adenosine 5â² diphosphate glucose pyrophosphorylase;
Anti-neuroinflammatory effects of SLOH in Aβ-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3β
Keywords: Aβ; Amyloid beta; AD; Alzheimer's disease; ANOVA; Analysis of variance; BBB; Blood-brain barrier; BCA; Bicinchoninic acid; BSA; Bovine serum albumin; COX-2; Cyclooxygenase-2; DAPI; 4â², 6-Diamidine-2â²-phenylindole dihydrochloride; DMEM; Dulbecco's m
Long-term inhibition of PDE5 ameliorates aging-induced changes in rat testis
Keywords: Actb/ACTB; gene/protein for β-actin; AKT; protein for protein kinase B (AKT/PRKGB); BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; Cyp11a1; gene for cytochrome P450 side chain cleavage enzyme; Cyp17
Influence of silibinin and β-β-dimethylacrylshikonin on chordoma cells
Keywords: Chordoma; β-β-dimethylacrylshikonin; Silibinin; Apoptosis; ACTB; actin beta; AKT; AKT serine/threonine kinase; BAD; BCL2 associated agonist of cell death; BAK; BCL2 antagonist/killer; BAX; BCL2 associated X protein; BCL-2; B cell leukemia/lymphoma 2; BH
Neuroprotective effect of a standardized extract of Centella asiatica ECa233 in rotenone-induced parkinsonism rats
Keywords: ECa233; Centella asiatica; Mitochondria; Rotenone; Parkinson's disease; ATP; adenosine-5â²- triphosphate; CMC; carboxymethylcellulose; DMSO; dimethyl sulfoxide; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HRP; horseradish peroxidase; MDA; malondiald
Apolipoprotein mediates soft-shelled turtle systemic septicemia spherical virus (STSSSV) infection
Keywords: STSSSV; soft-shelled turtle systemic septicemia spherical virus; PApoB; Pelodiscus sinensis apolipoprotein B; ApoB; apolipoprotein B; STSS; soft-shelled turtle systemic septicemia; Ab; antibody; VOPBA; viral overlay protein binding assay; PBS; phosphate b
Transmembrane topology of the arsenite permease Acr3 from Saccharomyces cerevisiae
Keywords: aa; amino acids; As(III); arsenite; As(V); arsenate; Endo H; endoglycosidase H; ER; endoplasmic reticulum; fXa; factor Xa protease; L; hydrophilic loop; NP-40; Nonidet P-40; Sb(III); antimonite; TM; transmembrane segment; Yeast; Arsenite; Transmembrane to
Postconditioning with Intralipid emulsion protects against reperfusion injury in post-infarct remodeled rat hearts by activation of ROS-Akt/Erk signaling
Keywords: ADP; adenosine diphosphate; Akt; protein kinase B; ANOVA; analysis of variance; ANP; atrial natriuretic peptide; ATP; adenosine triphosphate; BSA; bovine serum albumin; CAL; coronary artery ligation; COX; cytochrome c oxidase; CS; citrate synthase; DTNB;
N-Glycoform-dependent interactions of megalin with its ligands
Keywords: DBP; vitamin D-binding protein; Fut8; α1,6-fucosyltransferase; JCGGDB; Japan Consortium for Glycobiology and Glycotechnology Database; Kan; kanamycin; LCA; Lens culinaris agglutinin; LRP; LDL receptor-related protein; MAS; Matsunami Adhesive Silane; NP-4
New insights into the molecular mechanisms of chemical carcinogenesis: In vivo adduction of histone H2B by a reactive metabolite of the chemical carcinogen furan
Keywords: BDA; cis-2-butene-1,4-dial; GSH; glutathione; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; LC-HRMS; liquid chromatography-high resolution mass spectrometry; NP-40; nonyl phenoxypolyethoxylethanol; PMSF; phenylmethylsulfonyl fluoride; His
Pure Î9-tetrahydrocannabivarin and a Cannabis sativa extract with high content in Î9-tetrahydrocannabivarin inhibit nitrite production in murine peritoneal macrophages
Keywords: BSA; albumin bovine serum; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CBC; cannabichromene; CBD; cannabidiol; CBG; cannabigerol; COX-2; cyclooxygenase-2; DAN; 2,3-diaminonaphthalene; DMSO; dimethyl sulfoxide (DMSO); DTT; 1,4-dithi
Global regulation of alternative RNA splicing by the SR-rich protein RBM39
Keywords: ULM; U2AF ligand motif; snRNPs; small nuclear ribonucleoproteins; SR; serine/arginine-rich; RRMs; RNA-recognition motifs; RS domain; arginine- and serine-rich domain; VEGF; vascular endothelial growth factor; PNK; polynucleotide kinase; RPKM; reads per ki
Cysteine is not a substrate but a specific modulator of human ASCT2 (SLC1A5) transporter
Keywords: C12E8; octaethylene glycol monododecyl ether; MeAIB; (α-methylamino)isobutyric acid; BCH; 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid; YPDS; yeast extract peptone dextrose sorbitol; BMGY; buffered glycerol-complex medium; DOC; Na-deoxycholate; NP-40
N-linked Glycosylation of human SLC1A5 (ASCT2) transporter is critical for trafficking to membrane
Keywords: C12E8; octaethylene glycol monododecyl ether; BFA; brefeldin-A; DMEM; Dulbecco's Modified Eagle Medium; FBS; fetal bovine serum; TX-100; Triton X-100; NP-40; nonidet; MeAIB; α-(methylamino)isobutyric acid; BCH; 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic
BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (IKs)
Keywords: AP; action potential; APP; amyloid precursor protein; BACE1; β-site APP-cleaving enzyme 1; DMEM; Dulbecco's modified Eagle's medium; DTT; dithiothreitol; EGFP; enhanced green fluorescent protein; FRAP; fluorescence recovery after photobleaching; HEK293T;
Glycosmis pentaphylla (Retz.) DC arrests cell cycle and induces apoptosis via caspase-3/7 activation in breast cancer cells
Keywords: SRB Assay; sulforhodamine B assay; DMEM; Dulbecco's minimum essential media; FBS; fetal bovine serum; PI; propidium iodide; NP-40; nonidet P-40; PBS; phosphate buffer saline; DPPH assay; 1,1-diphenyl 1-2-picryl-hydrazyl assay; ABTS assay; 2,2â²-azino-b
Presence of a novel exon 2E encoding a putative transmembrane protein in human IL-33 gene
Keywords: cDNA; complementary DNA; DMEM; Dulbecco's Modified Eagle's Medium; EDTA; ethylenediaminetetraacetic acid; FBS; fetal bovine serum; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; NP-40; Nonidet P-40; RT-PCR; reverse transcription-polymerase chain rea
Deletion of the calmodulin-binding domain of Grb7 impairs cell attachment to the extracellular matrix and migration
Keywords: AEBSF; 4-(2-aminoethyl)-benzenesulfonyl fluoride; CaM; calmodulin; CaM-BD; calmodulin-binding domain; BPS; between PH and SH2; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbeccoâ²s modified Eagleâ²s medium; E-64; N-[N- (L-3-trans-carboxyirane-2-carbo
Identification of the major proteins of an immune modulating fraction from adult Fasciola hepatica released by Nonidet P40
Keywords: Anti-inflammatory; Heat shock protein; Proteomics; FhNPE; Fasciola hepatica; NP-40; released protein extract; NO; nitric oxide; ES; excretory/secretory;
PKCα and PKCβ cooperate functionally in CD3-induced de novo IL-2 mRNA transcription
Keywords: AP1; activator protein 1; cpm; counts per minute; EMSA; electrophoretic mobility shift assay; FACS; fluorescence activated cell sorter; ERK; extracellular regulated kinase; IL-2; interleukin-2; IFNγ; interferon gamma; IκB; inhibitor of NFκB; IKK; IκB
Hyaluronic acid-dependent protection in H9C2 cardiomyocytes: A cell model of heart ischemia-reperfusion injury and treatment
Keywords: HA; hyaluronic acid; 1-DE; one-dimensional gel electrophoresis; 2-DE; two-dimensional gel electrophoresis; BSA; bovine serum albumin; CCB; colloidal coomassie blue; CHAPS; 3-[(3-cholamidopropyl)-dimethylammonio]-1-propanesulfonate); ddH2O; double deionize
Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response
Keywords: RASMC; rat aortic smooth muscle cells; ER; endoplasmic reticulum; UPR; unfolded protein response; Grp; glucose regulated protein; PDI; protein disulfide isomerase; PERK; PKR-like ER kinase; IRE; inositol requiring enzyme; LC3; microtubule-associated prote
Role of vitelline envelope during fertilization in the black tiger shrimp, Penaeus monodon
Keywords: AR; acrosome reaction; ASW; artificial sea water; ECL; enhanced chemiluminescence; EW; egg water; NP-40; nonidet-40; PAB; p-amino benzamidine; TAPS; N-tris(hydroxymethyl)methyl-3-amino-propanesulfonic acid; TBS; Tris buffered saline; VE; vitelline envelop
Inhibition of GSK-3β reverses the pro-apoptotic effect of proadifen (SKF-525A) in HT-29 colon adenocarcinoma cells
Keywords: A; AR-A014418, GSK-3β inhibitor; ANOVA; analysis of variance; ATF3; activating transcription factor 3; Bax; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; Bcl-XL; B-cell lymphoma-extra large; DMSO; dimethyl sulfoxide; DOC-Na; sodium deoxycholate;
Active fraction from Ganoderma lucidum with apoptosis activity on peripheral blood mononuclear cells from chronic lymphocytic leukemia
Keywords: APL; acute promyelocytic leukemia; CLL; chronic lymphocytic leukemia; DMSO; dimethylsulfoxide; ESC/FL-2-H; forward scatter channel/fluorescent detector channel; FA; active fraction; NP-40; Nodinet P-40; PBS; phosphate buffered saline; PI; propidium iodide
Activation of the BRCA1/Chk1/p53/p21Cip1/Waf1 pathway by nitric oxide and cell cycle arrest in human neuroblastoma NB69 cells
Keywords: AEBSF; 4-(2-aminoethyl)-benzenesulfonyl fluoride; ATM; ataxia telangiectasia mutated; ATR; AT- and Rad3-related; BRCA1; breast cancer susceptibility protein-1; CDKI; cyclin-dependent kinase inhibitor; DAF-DA; 4,5-diaminofluorescein diacetate; Cdk; cyclin-
Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein
Keywords: 17-N-Allylamino-17-demethoxygeldanamycin (17-AAG):GABAA receptor-protein-like 1 (GABARAPL1); Glandular epithelial cell 1 (GEC1); Heat shock protein 90 (HSP90); Michigan cancer foundation-7 (MCF-7); Proteasome inhibitors; 17-AAG; 17-N-Allylamino-17-demetho
Identification of novel Sp1 targets involved in proliferation and cancer by functional genomics
Keywords: Sp1; Target; Genomics; Proliferation; Cancer; FDR; false discovery rate; GEO; gene expression omnibus; GO; gene ontology; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NE; nuclear extract; NP-40; nonyl phenoxypolyethoxylethanol; PPRHs
Hexapeptide library as a universal tool for sample preparation in protein glycosylation analysis
Keywords: AAT; α-1-antitrypsin; APTS; aminopyrene-1,3,6-trisulfonic acid; CHAPS; 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate; CSE; capillary sieving electrophoresis; FAC; formic acid; Ig; immunoglobulin; LIF; laser-induced fluorescence; NP-40; Nonide
The Nucleotide Synthesis Enzyme CAD Inhibits NOD2 Antibacterial Function in Human Intestinal Epithelial Cells
Keywords: NLR; Innate Immunity; IBD; PALA; CAD; carbamoyl phosphate synthetase/aspartate transcarbamylase/dihydroorotase; CARD; caspase recruitment domain; CPSII; carbamoyl phosphate synthetase II; LRR; leucine-rich repeat; MAPK; mitogen-activated protein kinase; M
Effects of antipsychotics with different weight gain liabilities on human in vitro models of adipose tissue differentiation and metabolism
Keywords: ADSCs; human adipose-derived stem cells; BMI; body mass index; C/EBPβ; CCAAT/enhancer-binding protein β; Ct; cycle threshold; Cy5; cyanine 5; DDX58; DEAD-box protein 58; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; FBS; fetal bovi
Near-full-length REV3L appears to be a scarce maternal factor in Xenopus laevis eggs that changes qualitatively in early embryonic development
Keywords: BSA; bovine serum albumin; CPD; cys-syn cyclobutane pyrimidine dimer; IP; immunoprecipitation; LSS; low-speed supernatant; NP-40; Nonidet P-40; ORF; open reading frame; PAGE; polyacrylamide gel electrophoresis; PMSF; phenylmethanesulfonyl fluoride; pol; D
Regulation of vascular smooth muscle cell bioenergetic function by protein glutathiolation
Keywords: RASMC; rat aortic smooth muscle cell; PSSG; protein-glutathione; XF; extracellular flux; OCR; oxygen consumption rate; ECAR; extracellular acidification rate; ECL; enhanced chemiluminescence; ROS; reactive oxygen species; FCCP; carbonyl cyanide p-[trifl
BAX insertion, oligomerization, and outer membrane permeabilization in brain mitochondria: Role of permeability transition and SH-redox regulation
Keywords: tBID; truncated BID; mPT; mitochondrial permeability transition; OMM; outer mitochondrial membrane; ER; endoplasmic reticulum; CsA; cyclosporin A; COX IV; cytochrome oxidase subunit IV; CHAPS; 3-[(3-cholamidopropyl) dimethylammonio]-1-propanesulfonate; NP
Coenzyme Q10 as a potent compound that inhibits Cdt1-geminin interaction
Keywords: CoQn; Coenzyme Qn; MCM; Mini-chromosome maintenance; pre-RC; Pre-replication complexes; ORC; Origin recognition complex; Cdk; Cyclin-dependent kinase; APC/C; Anaphase-promoting complex/cyclosome; HRP; Horseradish peroxidase; GST; Glutathione S-transferase
Vitamins A and D are potent inhibitors of cutaneous lymphocyte-associated antigen expression
Keywords: 1; 25-Dihydroxyvitamin D(3); retinoic acid; cutaneous lymphocyte-associated antigen; chemokine receptor; 7-ADD; 7-Amino-actinomycin; AP; Alkaline phosphatase; CCR; Chemokine receptor; CLA; Cutaneous lymphocyte-associated antigen; CTCL; Cutaneous T-cell ly
An optimized assay for transcription factor NF-κB with dsDNA-coupled microplate
Keywords: DNA; deoxyribonucleic acid; dsDNA; double-stranded DNA; ssDNA; single-stranded DNA; DBP; DNA-binding proteins; dcPlate; dsDNA-coupled plate; ELISA; enzyme-linked immunosorbent assay; NF-κB; nuclear factor kappaB; AP-1; activator protein-1; SP1; Sp1 trans
Scavenger receptor class B Type I (SR-BI) assembles into detergent-sensitive dimers and tetramers
Keywords: ABC; ATP binding cassette; apoA-I; apolipoprotein A-I; BLT; chemical that blocks lipid transport; BSA; bovine serum albumin; CE; cholesteryl ester; COE; cholesteryl oleyl ether; DMEM; Dulbecco's Minimal Essential media; DMSO; dimethylsulfoxide; EDTA; ethy
Scavenger receptor class B, type I (SR-BI) homo-dimerizes via its C-terminal region: Fluorescence resonance energy transfer analysis
Keywords: ACAT; acyl:CoA acyltransferase; apoA-I; apolipoprotein A-I; BSA; bovine serum albumin; CE; cholesteryl ester; CFP; monomeric enhanced cyan fluorescent protein; COE; cholesteryl oleyl ether; DLT; dilactitol tyramine; DMEM; Dulbecco's Minimal Essential medi
Human ubiquitin specific protease 31 is a deubiquitinating enzyme implicated in activation of nuclear factor-κB
Keywords: AP1; activator protein 1; DTT; dithiotreitol; DUB; deubiquitinating enzyme; EBV; Epstein-Barr virus; IKK; IκB kinase; JNK; Jun-kinase; LMP1; latent membrane protein 1; LTβR; lymphotoxin β receptor; MAPK; mitogen activated protein kinase; NP-40; Nonidet
Novel C-Raf phosphorylation sites: serine 296 and 301 participate in Raf regulation
Keywords: MS; mass spectrometry; RBD; Ras-binding domain; CRD; cysteine rich domain; NP-40; Nonidet P-40; LC; liquid chromatography; LC/MS-MS/MS; data-dependent tandem LC/MS; C-Raf kinase; Kinase assay; Phosphorylation; Mass spectrometry;
In vitro synthesis of enzymatically active HIV-1 protease for rapid phenotypic resistance profiling
Keywords: HIV-1; Human Immunodeficiency Virus Type 1; PI; protease inhibitor; RTS; Rapid Translation System; PR; protease; E. coli; Escherichia coli; RT; reverse transcriptase; IC; inhibitory concentration; Ki; inhibition constant; APV; amprenavir; IDV; indinavir;
HIV-1 incorporates and proteolytically processes human NDR1 and NDR2 serine-threonine kinases
Keywords: NDR; nuclear Dbf2 related; HIV-1; human immunodeficiency virus type 1; PR; protease; WT; wild type; CA; capsid; CIP; calf intestinal alkaline phosphatase; C-PKA; cAMP-dependent protein kinase; DMSO; dimethyl sulfoxide; GFP; green fluorescent protein; PMSF
Gpi17p does not stably interact with other subunits of glycosylphosphatidylinositol transamidase in Saccharomyces cerevisiae
Keywords: BCS; bathocuproinedisulfonic acid; GPI; glycosylphosphatidylinositol; NP-40; Nonidet P-40; TMD; transmembrane domain; UPR; unfolded protein response; wt; wild type; GPI17; Glycosylphosphatidylinositol; Transamidase; Saccharomyces; Protein stability; Unfol
A method for fabricating uni-dsDNA microarray chip for analyzing DNA-binding proteins
Keywords: DNA; Deoxyribonucleic acid; PCR; Polymerase chain reaction; NF-κB; Nuclear factor κB; AP1; Activator protein 1; dNTP; Deoxynucleoside triphosphate; PBS; Phosphate-buffered saline; TNF-α; Tumor necrosis factor α; EDTA; Ethylenediaminetetraacetic acid;
A hemocyte-specific integrin required for hemocytic encapsulation in the tobacco hornworm, Manduca sexta
Keywords: Hemocyte; Cell adhesion; Encapsulation; Insect immunity; Innate immunity; mAb; monoclonal antibody; AC; anticoagulant saline; MSB; Manduca saline buffer; PBS; phosphate buffered saline; PAGE; polyacrylamide gel electrophoresis; RACE; rapid amplification o
DNA polymerases η and κ are responsible for error-free translesion DNA synthesis activity over a cis-syn thymine dimer in Xenopus laevis oocyte extracts
Keywords: AP; apurinic/apyrimidinic; BSA; bovine serum albumin; CPD; cys-syn cyclobutane pyrimidine dimer; dNTP; deoxyribonucleoside triphosphate; DTT; dithiothreitol; IPTG; isopropyl l-thio-β-d-galactoside; NP-40; Nonidet P-40; PAGE; polyacrylamide gel electrop