کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5845262 1128046 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of antipsychotics with different weight gain liabilities on human in vitro models of adipose tissue differentiation and metabolism
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Effects of antipsychotics with different weight gain liabilities on human in vitro models of adipose tissue differentiation and metabolism
چکیده انگلیسی
► Uncertainties exist concerning the effects of antipsychotics on human adipose tissue. ► We used antipsychotic drugs with different propensities to induce body weight gain. ► Clozapine and olanzapine did not exert direct effects on human adipose tissue in vitro. ► Haloperidol clearly inhibited the lipogenic capacity of human mature adipocytes in vitro. ► We suggest a novel mechanism contributing to haloperidol lower weight gain liability.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Neuro-Psychopharmacology and Biological Psychiatry - Volume 35, Issue 8, 1 December 2011, Pages 1884-1890
نویسندگان
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