Keywords: bFGF; basic fibroblast growth factor; CMH; 1-hydroxy-3methoxycarbonyl-2,2,5,5-tetramethylpyrolidin; EC; endothelial cell; EDTA; ethylenediaminetetraacetic acid; EGM-2; endothelial cell growth medium; EPR; electron paramagnetic resonance; ERα; estrogen re
مقالات ISI (ترجمه نشده)
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Keywords: AIF; apoptosis-inducing factor; ASL; argininosuccinate lyase; ASS; argininosuccinate synthetase; AST; aspartate aminotransferase; BER; base excision repair; cGC; cyclic guanylyl cyclase; CNS; central nervous system; DRP-1; dynamin-related protein 1; EAE;
Keywords: ALCAR; Acetyl-l-carnitine; mtDNA; mitochondrial DNA; nDNA; nuclear DNA; CS; citrate synthase; PGC-1α; peroxisome proliferator-activated receptor γ [PPARγ] coactivator-1α; PGC-1β; peroxisome proliferator-activated receptor γ [PPARγ] coactivator-1 β
Keywords: IL-6; interleukin-6; ND; normal diet; HFD; high fat diet; FAs; fatty acids; CD36; cluster of differentiation 36; MCP-1; monocyte chemoattractant protein 1; PPARα; peroxisome proliferator-activated receptor α; CPT-1; carnitine palmitoyltransferase 1; End
Keywords: DAG; diacylglycerol; dN/dS; rate of nonsynonymous-to-synonymous amino acid substitutions; EF-1α; elongation factor-1 alpha; G3P; glycerol 3-phosphate; GPAT; glycerol 3-phosphate acyltransferase; HKG; housekeeping gene; LPA; lysophosphatidic acid; LPAAT;
Keywords: AGO; adrenal gland oncocytoma; BHDS; Birt-Hogg-Dubée syndrome; CCRCC; clear cell renal cell carcinoma; CD; mtDNA common deletion; DAP3; death-associated protein 3; DCA; dichloroacetate; ERRα; estrogen-related receptor alpha; ETC; electron transport chai
Keywords: MB; methylene blue; ND; neurodegenerative diseases; CNS; central nervous system; ETC; electron transport chain; ROS; reactive oxygen species; Nrf2/ARE; NF-E2-related factor 2/antioxidant response element; NRF-1; nuclear respiratory factor 1; TFAM; transcr
Keywords: ABCA1; ATP-binding cassette transporter 1; ABCG1; ATP Binding Cassette G1; AMPK; 5â²AMP-activated protein kinase; AP-1; activator protein 1; apo A-I; apolipoproteins A-I; AT; adipose tissue; CCK-1; cholecystokinin; CD; Crohn's disease; CVD; cardiovascula
Keywords: Breast cancer; NRF-1; Mitochondrial oxidative phosphorylation; Tamoxifen-resistance
Keywords: GLUT; Glucose transporter; T1DM; Type-1 diabetes mellitus; T2DM; Type-2 diabetes mellitus; PKB/Akt; protein kinase B; GSK-3; glycogen synthase kinase-3; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator-1α; FOXO; forkhead box O; VLDL;
Keywords: AA; antimycin; AICAR; 5-aminoimidazole-4-carboxamide-1-b-d-ribofuranoside; AMPK; 5â² AMP-activated protein kinase; Ap5A; P1,P5-Di(adenosine-5â²) pentaphosphate; ASC; ascorbate; BrdU; bromodeoxyuridine; CC; Compund C; CNâ; Â cyanide; DCF; dichlorofluor
Keywords: Mir; microRNA; DNMT; DNA methyltransferase; CBS; cystathionine β-synthase; HHcy; hyperhomocysteinemia; Hcy; homocysteine; mtTFA; mitochondrial transcription factor A; Mfn2; mitofusion 2; H3K18; histone H3 lysine 18; LDH; lactate dehydrogenase; CS; citrat
Keywords: AICAR; 5â²aminoimidazole-4-carboxyamide-ribonucleoside; AD; Alzheimer's disease; ATF-2; activating transcription factor-2; AMPK; AMP-activated protein kinase; Bnip3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; BnipL/Nix; BCL2/adenovirus E1B 19Â
Keywords: AP-1; activator protein-1; BACH1; BTB and CNC homology 1, basic leucine zipper transcription factor 1; CDK; cyclin-dependent kinase; CYP1A1; cytochrome P450, family 1, subfamily A, polypeptide 1; ERK; extracellular signal-regulated kinase; FACS; Fluoresce
Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1α/mitochondrial biosynthesis pathway
Keywords: ADH; alcohol dehydrogenase; ALD; Alcoholic liver disease; ALDH; aldehyde dehydrogenase; CPT-1α; carnitine palmitoyl transterase-1α; CR; calorie restriction; CS; citrate synthase; CYP2E1; cytochrome P450 2E1; FASN; fatty acid synthase; NAD+; nicotinamide
ROS and redox signaling in myocardial ischemia-reperfusion injury and cardioprotection
Keywords: Akt; protein kinase B or PKB; AMPK; 5â²-AMP-activated protein kinase; CcO; cytochrome c oxidase; CsA; cyclosporin A; Cx43; connexin 43; CyP-D; cyclophilin D; DMOG; dimethyloxalylglycine; ETC; electron transport chain; GSK-3; glycogen synthase kinase 3; H
Functional genetic variants in the SIRT5 gene promoter in acute myocardial infarction
Keywords: AMI; acute myocardial infarction; CAD; coronary artery disease; CEBPB; CCAAT/enhancer binding protein β; DSVs; DNA sequence variants; EMSA; electrophoretic mobility shift assay; FOXC1; forkhead box C1; H9c2; rat cardiomyocyte line; HEK-293; human embryon
Heme oxygenase-1 protects liver against ischemia/reperfusion injury via phosphoglycerate mutase family member 5-mediated mitochondrial quality control
Keywords: ALT; Alanine aminotransferase; Drp1; dynamin-related protein 1; EDTA; ethylenediaminetetraacetic acid; GDH; glutamate dehydrogenase; H&E; hematoxylin&eosin; HO-1; heme oxygenase-1; H/R; hypoxia/reoxygenation; IL; interleukin; I/R; ischemia/reperfusion; LP
Mitochondria as pharmacological targets in Down syndrome
Keywords: AD; Alzheimer's disease; AGO; Argonaute proteins; AMPK; AMP-activated protein kinase; ANTs; adenine nucleotide translocators; AK; adenylate kinase; APP; amyloid-β precursor protein; ASD; autism spectrum disorder; CAT; catalase; CNS; central nervous syste
Balasubramide derivative 3C modulates microglia activation via CaMKKβ-dependent AMPK/PGC-1α pathway in neuroinflammatory conditions
Keywords: AMPK; AMP-activated protein kinase; CaMKKβ; calcium/calmodulin-dependent protein kinase kinase beta; CBF; cerebral blood flow; CCA; common carotid artery; EBSS; glucose-free Earle's balanced salt solution; ECA; external carotid artery; ELISA; cytokine en
Exercise increases hyper-acetylation of histones on the Cis-element of NRF-1 binding to the Mef2a promoter: Implications on type 2 diabetes
Keywords: Exercise; CaMKII; NRF-1; MEF2A; Hyper-acetylation; Type 2 diabetes;
Molecular drivers of mitochondrial membrane proliferation in response to cold acclimation in threespine stickleback
Keywords: AGPAT; 1-acylglycerol 3-phosphate acyltransferase; CDP-DAG; cytidine diphosphodiacylglycerol; CDS; cytidine diphosphodiacylglycerol synthase; CL; cardiolipin; DAG; diacylglycerol; EF-1α; elongation factor-1 alpha; G3P; glycerol 3-phosphate; GPAT; glycero
Effect of novel dietary supplement on metabolism in vitro and in vivo
Keywords: Obesity; Thermogenic agent; Fat burner; Resting energy expenditure; Mitochondrial biogenesis; Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α); GLUT4; Glucose transporter 4; TFAM; Mitochondrial transcription factor A; NRF-1; Nuclear
Mild palmitate treatment increases mitochondrial mass but does not affect EA.hy926 endothelial cells viability
Keywords: Endothelial cells; Inflammatory response; Mitochondrial mass; Palmitate; Reactive oxygen species; BSA; bovine serum albumin; Cu/Zn-SOD (SOD1); copper/zinc superoxide dismutase; eNOS; endothelial nitric oxide synthase; HUVEC; human umbilical vein endotheli
Globular CTRP3 promotes mitochondrial biogenesis in cardiomyocytes through AMPK/PGC-1α pathway
Keywords: AMPK; AMP-activated protein kinase; AraA; adenine 9-β-d-arabinofuranoside; ATP-5β; ATP synthase 5β; Cyt B; cytochrome B; CTRP3; C1q/tumor necrosis factor-related protein-3; FCCP; carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone; H/R; hypoxia-reoxy
Spatio-temporal coordination of cell cycle exit, fusion and differentiation of adult muscle precursors by Drosophila Erect wing (Ewg)
Keywords: Drosophila; Erect wing; Cyclin E; Muscle development; NRF-1
Research articlePost-ischemia mdivi-1 treatment protects against ischemia/reperfusion-induced brain injury in a rat model
Keywords: mdivi; 1 mitochondrial division inhibitor-1; Drp1; dynamin-related protein 1; PGC-1α; peroxisome proliferator-activated receptor coactivator-1α; NRF-1; nuclear respiratory factor-1; TFAM; mitochondrial transcription factor A; Cyt-C; cytochrome C; COX-
Epigallocatechin gallate and mitochondria-A story of life and death
Keywords: ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; ALT; alanine aminotransferase; AMP; adenosine monophosphate; AP-1; activator protein-1; ASK1; apoptosis signal-regulating kinase 1; ATP; adenosine triphosphate; Bax; BCL2-Associated X Protein; Bc
Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism
Keywords: ARE; antioxidant response element; ATP; adenosine triphosphate; 5-hmC; hydroxymethylcytosine; ATG; AuTophaGy related; BNIP; Bcl-2/adenovirus E18 19-kDa-interacting protein; Drp1; dynamin related protein 1; EpRE; electrophile response element; eNOS; endoth
BPA-induced DNA hypermethylation of the master mitochondrial gene PGC-1α contributes to cardiomyopathy in male rats
Keywords: ATP5E; ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit; ATP5O; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit; BPA; bisphenol A; CpG; cytosine phosphate guanine; DNMT3A; DNA methyltransferase 3A; DNMT3B; DNA me
The plasticizer BBP selectively inhibits epigenetic regulator sirtuins
Keywords: BBP; benzyl butyl phthalate; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator 1-alpha; NRF-1; nuclear respiratory factor 1; NRF-2; nuclear respiratory factor 2; Sirtuins; Benzyl butyl phthalate (BBP); Metabolic syndrome; Mitochondria;
Pyrroloquinoline quinone increases the expression and activity of Sirt1 and -3 genes in HepG2 cells
Keywords: Sirtuins; Pyrroloquinoline quinone; Metabolic syndrome; Mitochondria; Aging; Mitochondrial biogenesis regulators; CR; caloric restriction; mRNA; messenger RNA; NAMPT; nicotinamide phosphoribosyltransferase; NRF-1; nuclear respiratory factor 1; NRF-2; nucl
Redox modulation of mitochondriogenesis in exercise. Does antioxidant supplementation blunt the benefits of exercise training?
Keywords: Akt; protein kinase B; AMPK; 5â²-AMP-activated protein kinase; AP-1; activator protein 1; COX IV; cytochrome c oxidase; CuZnSOD; copper/zinc superoxide dismutase; DMSO; dimethyl sulfoxide; eNOS; endothelial nitric oxide synthase; ERK; extracellular signa
Vitamin C and E supplementation prevents some of the cellular adaptations to endurance-training in humans
Keywords: ROS; reactive oxygen species; COX IV; cytochrome c oxidase subunit 4; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator 1α; CS; citrate synthase; VO2peak; peak oxygen consumption; Wmax; maximal power output; Wfinal; final completed wo
Negative transcriptional regulation of mitochondrial transcription factor A (TFAM) by nuclear TFAM
Keywords: Nuclei; TFAM; NRF-1; Repressor; Promoter regulation;
Delphinidin inhibits VEGF induced-mitochondrial biogenesis and Akt activation in endothelial cells
Keywords: ER; estrogen receptor; ERRα; estrogen-related receptor α; FCCP; carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone; Delph; delphinidin; HUVECs; human umbilical vein endothelial cells; mtDNA; mitochondrial DNA; ND5; NADH dehydrogenase subunit 5; NO; n
Glycogen synthase kinase-3 (GSK3) controls deoxyglucose-induced mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells
Keywords: AMPK; AMP-activated protein kinase; mtCOXII; Mitochondrial cytochrome c oxidase subunit II; mtCOXIII; Mitochondrial cytochrome c oxidase subunit III; mtCYTB; Mitochondrial cytochrome b; 2-DG; 2-Deoxyglucose; GAPDH; Glyceraldehyde-3-phosphate dehydrogenase
Effects of salinity on metabolic rate and branchial expression of genes involved in ion transport and metabolism in Mozambique tilapia (Oreochromis mossambicus)
Keywords: Osmoregulation; Respirometry; Osmolality; Mitochondria-rich cells; Mitochondrial biogenesis; NKCC; NCC; PGC-1α; NRF-1; COX
MDG-1, a polysaccharide from Ophiopogon japonicus, prevents high fat diet-induced obesity and increases energy expenditure in mice
Keywords: Ophiopogon japonicus; Polysaccharide; Anti-obesity; Energy expenditure; Diet induced obesity; Mitochondrial function; T2DM; type 2 diabetes mellitus; HFD; high fat diet; qPCR; quantitative real-time polymerase chain reaction; RER; respiratory exchange rat
ATF3 plays a role in adipocyte hypoxia-mediated mitochondria dysfunction in obesity
Keywords: ATF3; activating transcription factor 3; COX1; cytochrome C oxidase 1; HIF-1α; hypoxia inducible factor-1; HFD; high fat diet; MTT; 3-(4, 5 dimethylthiazol-2-yl)-2, 5-diphenyl-tetrazolium bromide; NRF-1; nuclear respiratory factor 1; SOD; superoxide dism
The effect of overexpression of PGC-1α on the mtDNA4834 common deletion in a rat cochlear marginal cell senescence model
Keywords: AHL; age-related hearing loss; PGC-1α; peroxisome proliferator-activated receptor-gamma coactivator 1α; MCs; marginal cells; EP; endocochlear potential; CD; common deletion; NRF-1; nuclear respiratory factor-1; Tfam; mitochondrial transcription factor A
Aluminium induced oxidative stress results in decreased mitochondrial biogenesis via modulation of PGC-1α expression
Keywords: ROS; Reactive oxygen species; PGC-1α; Peroxisome proliferator activated receptor gamma co-activator 1a; NRF-1; Nuclear respiratory factor-1; NRF-2; Nuclear respiratory factor-2; Tfam; Mitochondrial transcription factor A; ND; NADH dehydrogenase; Cyt b; C
Exercise induces mitochondrial biogenesis after brain ischemia in rats
Keywords: exercise; mitochondrial biogenesis; ischemic; neuroprotection; COXIV; C oxidase subunit IV; HSP60; heat shock protein-60; MCAO; middle cerebral artery occlusion; mtDNA; mitochondrial DNA; NRF-1; nuclear respiratory factor 1; PCR; polymerase chain reaction
Cardiovascular effects and molecular targets of resveratrol
Keywords: 4-HNE; 4-hydroxy-2-nonenal; ADMA; asymmetric dimethylarginine; AMPK; AMP-activated protein kinase; ApoE; apolipoprotein E; ARE; antioxidant response element; BH4; tetrahydrobiopterin; Cav-1; caveolin-1; COX-1; cyclooxygenase 1; CREB; cAMP response element
Nrf2 promotes alveolar mitochondrial biogenesis and resolution of lung injury in Staphylococcus aureus pneumonia in mice
Keywords: Acute lung injury; IL-10; Inflammation; Mitochondria; Oxidative stress; NRF-1; Nrf2; Free radicals;
Transcription factor GABP/NRF-2 controlling biogenesis of mitochondria regulates basal expression of peroxiredoxin V but the mitochondrial function of peroxiredoxin V is dispensable in the dog
Keywords: Peroxiredoxin 5; GA-binding protein; Gene expression regulation; Alternative translation; Gene expression; Transcription; Translation; ETS; a family of transcription factors; EBS; ETS binding site; PRDX; peroxiredoxin; NRF-1; nuclear respiratory factor 1;
Recent progress toward understanding the molecular mechanisms that regulate skeletal muscle mass
Keywords: 4E-BP1; 4E binding protein 1; 5â²UTR; 5â² untranslated region; AICAR; 5-aminoimidazole-4-carboxamide riboside; AMP; adenosine monophosphate; AMPK; 5â²-AMP-activated protein kinase; AMPK α1â/â; AMPK α1 subunit knockout; AMPKα1â/âα2â/â; A
PGC-1β-Regulated mitochondrial biogenesis and function in myotubes is mediated by NRF-1 and ERRα
Keywords: PGC-1β; NRF-1; ERRα; Cytochrome c; Mitochondrial biogenesis; Energy metabolism
The PGC-1α-dependent pathway of mitochondrial biogenesis is upregulated in type I endometrial cancer
Keywords: PGC-1α, PPARγ-coactivator-1α; TFAM, mitochondrial transcription factor A; NRF-1, nuclear respiratory factor 1Type I endometrial cancer; Mitochondrial biogenesis; PGC-1α; NRF-1; TFAM; mtDNA content