Keywords: AhR; aryl hydrocarbon receptor; AKT/PKB; protein kinase B; AOM; azoxymethane; AP; Acticoa power; AP-1; activator protein-1; ARE; antioxidant response element; CDK; cyclins-dpendent kinase; CLPr; cacao liquor proanthocyanidins; COX-2; cyclooxygenase-2; CYP
مقالات ISI (ترجمه نشده)
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Keywords: ACD; anemia of chronic disease; AID; absolute iron deficiency; ARE; antioxidant-responsive elements; asc; ascorbic acid; DMT1; divalent metal transporter 1; eNOS; endothelial nitric oxide synthase; EPO; erythropoietin; FBXL5; F-box and leucine-rich repeat
Keywords: ARE; antioxidant response element; APAP; acetaminophen; EGF; epidermal growth factor; ERK; Extracellular signal-regulated kinase; ECM; extracellular matrix; HO-1; heme oxygenase-1; HSC; hepatic stellate cells; HCC; hepatocellular carcinoma; ITC; isothiocy
Keywords: Osteosarcoma; Nrf2; Keap1
Keywords: Osteoclast; Oxidative stress; Heme-oxygenase 1 (HO-1); Nrf2; FOXO; Sirtuin
Keywords: Nrf2; Kidney; Nephrotoxicity; Cisplatin; Sulforaphane; Oltipraz; Oleanolic acid
Keywords: Sb, Antimony; NAC, N-acetylcysteine; Nrf2, NF-E2-related factor 2; ROS, Reactive oxygen species; Sb2O3, Antimony trioxide; TBHQ, Tertiary butylhydroquinoneAntimony; Apoptosis; Nrf2; Gadd45b; ROS
Keywords: Tangeretin; Cisplatin; Renal injury; NF-κB; Nrf2; ApoptosisBUN, blood urea nitrogen; GSH, glutathione; GPx, glutathione peroxidase; H&E, hematoxylin and eosin; IL-10, interleukin-10; iNOS, inducible nitric oxide synthase; MDA, malondialdehyde; MPO, myelop
Keywords: Selenium; NRF2; Cytoprotective genes; Gene expression; Human circulating leukocytes
Keywords: ARE; antioxidant response element; BVR; biliverdin reductase; CD; cytosine deaminase; DBD; DNA binding domain; Epo; erythropoietin; 5-FC; 5-fluorocytosine; GALC; galactocerebrosidase; HIF; hypoxia inducible factor; HO-1; heme oxygenase-1; HRE; hypoxia res
Identification and characterisation of a G-quadruplex forming sequence in the promoter region of nuclear factor (erythroid-derived 2)-like 2 (Nrf2)
Keywords: G-quadruplex; Nrf2; 9-Aminoacridine; Inflammation; Cancer;
Pilot-scale produced fermented lentil protects against t-BHP-triggered oxidative stress by activation of Nrf2 dependent on SAPK/JNK phosphorylation
Keywords: ACE; angiotensin I converting enzyme; ACN; acetonitrile; ARE; antioxidant response element; t-BHP; tert-butyl hydroperoxide; DCF; dichlorofluorescein; DCFDA; dichlorofluorescein diacetate; DMEM; High-glucose Dulbecco's Modified Eagle's Medium; FA; for
Environmentally relevant concentration of chromium activates Nrf2 and alters transcription of related XME genes in liver of zebrafish
Keywords: Chromium; Environmentally relevant; Oxidative stress; Hepatotoxicity; Nrf2; Zebrafish;
The putative interplay between DJ-1/NRF2 and Dimethyl Fumarate: A potentially important pharmacological target
Keywords: NRF2; transcription factor nuclear factor (erythroid derived 2)-like2 (NRF2); KEAP1; Kelch-like erythroid cell-derived (ECH) associated protein-1; MMF; monomethyl fumarate; DMF; Dimethyl Fumarate; ARE; antioxidant response element; ROS; reactive oxygen sp
Perfluoroarene-based peptide macrocycles that inhibit the Nrf2/Keap1 interaction
Keywords: Nrf2; Keap1; Protein-protein interaction; Hexafluorobenzene; Peptide;
Isoalantolactone protects LPS-induced acute lung injury through Nrf2 activation
Keywords: Isoalantolactone; LPS; Lung injury; NF-κB; Nrf2;
Reactive oxygen species participate in liver function recovery during compensatory growth in zebrafish (Danio rerio)
Keywords: Compensatory growth; Zebrafish; Liver; Reactive oxygen species; nrf2; mTOR;
Xanthohumol attenuates cisplatin-induced nephrotoxicity through inhibiting NF-κB and activating Nrf2 signaling pathways
Keywords: Xanthohumol; Cisplatin; Nrf2; Nephrotoxicity;
Ropivacaine regulates the expression and function of heme oxygenase-1
Keywords: Heme oxygenase-1; Local anesthetics; Ropivacaine; Nrf2; ROS;
Sinomenine protects against E.coli-induced acute lung injury in mice through Nrf2-NF-κB pathway
Keywords: Sinomenine; Acute lung injury; Nrf2; NF-κB;
Neuroprotective effect of Nrf2 activator dimethyl fumarate, on the hippocampal neurons in chemical kindling model in rat
Keywords: CNS; central nervous system; DMF; dimethyl fumarate; PTZ; pentylenetetrazole; VPA; sodium valproate; Nrf2; nuclear factor erythroid-2 related factor 2; GPx; glutathione peroxidase; SOD; superoxide dismutase; GSH; reduced glutathione; HO-1; heme oxygenase
4-Methylthio-3-butenyl isothiocyanate mediates nuclear factor (erythroid-derived 2)-like 2 activation by regulating reactive oxygen species production in human esophageal epithelial cells
Keywords: Chemoprevention; Isothiocyanate; 4-Methylthio-3-butenyl isothiocyanate; Nuclear factor (erythroid-derived 2)-like 2; Reactive oxygen species; AITC; allyl isothocyanate; AP-1; activator protein-1; BITC; butyl isothiocyanate; ERK; extracellular signal-regul
Protective effects of dietary luteolin against mercuric chloride-induced lung injury in mice: Involvement of AKT/Nrf2 and NF-κB pathways
Keywords: Luteolin; Mercury; Lung injury; AKT/Nrf2; NF-κB; Apoptosis; AKT; protein kinase B; Bax; Bcl-2-associated X protein; DMSO; dimethylsulfoxide; GSH; glutathione; H&E; hematoxylin and eosin; HgCl2; mercuric chloride; HO-1; heme oxygenase 1; IL6; Interleukin-
Luteolin-mediated PI3K/AKT/Nrf2 signaling pathway ameliorates inorganic mercury-induced cardiac injury
Keywords: ROS; reactive oxygen species; HgCl2; mercuric chloride; Lut; Luteolin; CK; creatine kinase; CK-MB; creatine kinase myocardial band isoenzyme; Nrf2; nuclear factor-erythroid-2-related factor 2; PI3K; phosphatidylinositol 3-kinase; P-PI3K; phospho-PI3K; AKT
Epigallocatechin-3-gallate attenuates microcystin-LR-induced apoptosis in human umbilical vein endothelial cells through activation of the NRF2/HO-1 pathway
Keywords: Epigallocatechin-3-gallate; Microcystin-LR; Human umbilical vein endothelial cells; Oxidative stress; NRF2;
Dihydromyricetin relieves rheumatoid arthritis symptoms and suppresses expression of pro-inflammatory cytokines via the activation of Nrf2 pathway in rheumatoid arthritis model
Keywords: Rheumatoid arthritis; Dihydromyricetin; Oxidative stress; Nrf2;
Ferroptosis is a lysosomal cell death process
Keywords: Ferroptosis; STAT3; Lysosomal cell death; Autophagy; Cathepsin; PDAC; pancreatic ductal adenocarcinoma; STAT3; signal transducer and activator of transcription 3; GPX4; glutathione peroxidase 4; NRF2; nuclear factor erythroid 2-related factor 2; Q-PCR; qu
Two new flavonoid-triterpene saponin meroterpenoids from Clinopodium chinense and their protective effects against anoxia/reoxygenation-induced apoptosis in H9c2 cells
Keywords: Lamiaceae; Clinopodium chinense; Favonoid-triterpene saponin meroterpenoid; Myocardial protection; NF-kB; Nrf2;
Nrf2 overexpression is associated with P-glycoprotein upregulation in gastric cancer
Keywords: Gastric cancer; Nrf2; MDR1/P-gp; Chemotherapy; Clinicopathological criteria;
Nrf2/P-glycoprotein axis is associated with clinicopathological characteristics in colorectal cancer
Keywords: ABCB1/Pâgp; Chemotherapy; Clinicopathological criteria; Colorectal cancer; Keap1; Nrf2;
Novel approaches in the treatment of diabetic cardiomyopathy
Keywords: ACE; angiotensin convertase enzyme; ACEi; angiotensin convertase enzyme inhibitor; ADP; adenosine di phosphate; AGE; advanced glycation end products; AM; adrenomedullin; AMP; adenosine mono phosphate; ARB; angiotensin receptor blocker; ATP; adenosine tri
The regulatory role of Nrf2 in antioxidants phase2 enzymes and IL-17A expression in patients with ulcerative colitis
Keywords: ROS; reactive oxygen species; UC; ulcerative colitis; Nrf2; nuclear factor erythroid 2 related factor 2; IBD; inflammatory bowel diseases; DSS; dextran sodium sulfate; IL-17; interleukin-17; APE1; apurinic/apyrimidinic endonuclease; PRDX1; peroxiredoxin-1
Bardoxolone methyl induces neuritogenesis in Neuro2a cells
Keywords: Akt; v-Akt Murine Thymoma Viral Oncogene; ARE; Antioxidant Responsive Element; BDNF; Brain Derived Neurotrophic Factor; CDDO; 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid; CHOP; C/EBP homologous protein; DR5; Death Receptor 5; ERK; Extracellular signal Re
ETS transcription factor family member GABPA contributes to vitamin D receptor target gene regulation
Keywords: 1,25(OH)2D3 or 1,25D1α; ,25-dihydroxyvitamin D3; ChIP; chromatin immunoprecipitation; ChIP-seq; ChIP sequencing; CTCF; CCCTC-binding factor; DR3; direct repeat of hexameric binding sites spaced by 3 nucleotides; ETS; E-twenty-six; FAIRE-seq; Formaldehyde
PF-06409577 activates AMPK signaling to protect retinal pigment epithelium cells from UV radiation
Keywords: Retinal pigment epithelium cells; PF-06409577; UVR; AMPK; Oxidative stress; Nrf2;
CART peptide activates the Nrf2/HO-1 antioxidant pathway and protects hippocampal neurons in a rat model of Alzheimer's disease
Keywords: Alzheimer's disease (AD); Amyloid-beta (Aβ); Oxidative stress; Antioxidant; CART peptide; Nrf2;
Neuroligin-3 protects retinal cells from H2O2-induced cell death via activation of Nrf2 signaling
Keywords: Neuroligin-3; Retinal cells; Oxidative stress; Nrf2; AktmTORC1; Signaling;
Nrf2 inhibits NLRP3 inflammasome activation through regulating Trx1/TXNIP complex in cerebral ischemia reperfusion injury
Keywords: Nuclear factor erythroid 2-related factor 2; Nod-like receptor protein 3 inflammasome; Thioredoxin1; Thioredoxin interacting protein; Inflammation; NLRP3; nod-like receptor protein 3; TXNIP; thioredoxin interacting protein; Trx1; thioredoxin1; Nrf2; nucle
Immunohistochemical localization of Nrf2 in the human cochlea
Keywords: Nrf2; Oxidative stress; Cochlea; Sensory hair cells; Supporting cells; Hearing loss;
Polyphenols extracted from Coreopsis tinctoria buds exhibited a protective effect against acute liver damage
Keywords: Coreopsis tinctoria; Polyphenol; Hepatoprotective; Antioxidant activity; Anti-inflammatory response; ALT; alanine aminotransferase; AST; aspartate transaminase; CAT; catalase; CTB-PE; polyphenols extracted from C. tinctoria buds; D-GalN; D-galactosamine;
C1q tumor necrosis factor-related protein 9 in atherosclerosis: Mechanistic insights and therapeutic potential
Keywords: CTRP9; AdipoR1; N-cadherin; Atherosclerosis; Adiponectin; CVD; cardiovascular disease; CTRPs; C1q tumor necrosis factor-related proteins; AMI; acute myocardial infarction; HMW; high molecular weight; AMPK; adenosine monophosphate-activated protein kinase;
Inhibition of Nrf2 alters cell stress induced by chronic iron exposure in human proximal tubular epithelial cells
Keywords: Iron overload; Oxidative stress; Nrf2; ER stress; Renal proximal tubular epithelial cell;
Shikonin upregulates the expression of drug-metabolizing enzymes and drug transporters in primary rat hepatocytes
Keywords: AhR; aryl hydrocarbon receptor; AP1; activating protein 1; ARE; antioxidant-response element; CAR; constitutive androstane receptor; CYP; cytochrome P450; DREs; dioxin-responsive elements; EMSA; electromobility gel shift assay; FBS; fetal bovine serum; GS
Protective effects of a traditional Chinese herbal formula Jiang-Xian HuGan on Concanavalin A-induced mouse hepatitis via NF-κB and Nrf2 signaling pathways
Keywords: Autoimmune hepatitis; Concanavalin A; JXHG; NF-κB; Nrf2;
Cordycepin alleviates lipopolysaccharide-induced acute lung injury via Nrf2/HO-1 pathway
Keywords: Cordycepin; Lipopolysaccharide; Acute lung injury; Nrf2; Heme oxygenaseâ1;
Pogostone attenuates TNF-α-induced injury in A549 cells via inhibiting NF-κB and activating Nrf2 pathways
Keywords: Acute lung injury; NF-κB p65; Nrf2; Pogostone; TNF-α;
Suppression of Nrf2 confers chemosensitizing effect through enhanced oxidant-mediated mitochondrial dysfunction
Keywords: Nrf2; Antioxidant; Cholangiocarcinoma; Chemosensitization; Mitochondrial transmembrane potential; Luteolin;
Aucubin protects against lipopolysaccharide-induced acute pulmonary injury through regulating Nrf2 and AMPK pathways
Keywords: Aucubin; Acute lung injury; Nrf2; AMPK; Oxidative stress and inflammation;
Treatment targets for M2 microglia polarization in ischemic stroke
Keywords: PACAP; pituitary adenylate cyclase-activating polypeptide; OGA; beta-N-acetylglucosaminidase; FAM19A3; TAFA3, TAFA family (TAFA1-5); TPA; tissue plasminogen activator; GSH; glutathione-SH; NGF; nerve growth factor; BCL-2/BCL-X1; B cell leukemia/lymphoma
Research reportPharmacological activation of the Nrf2 pathway by 3H-1, 2-dithiole-3-thione is neuroprotective in a mouse model of Alzheimer disease
Keywords: Alzheimer's disease; D3T; Cognition; Oxidative stress; Hippocampal neurogenesis; Sirt1; Nrf2;