Keywords: هیدرولاز نوکلئوزید; Nucleoside hydrolase; Molecular dynamics (MD) simulations; Base release; Loop motion; Umbrella sampling;
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New nucleoside hydrolase with transribosylation activity from Agromyces sp. MM-1 and its application for enzymatic synthesis of 2â²-O-methylribonucleosides
Keywords: هیدرولاز نوکلئوزید; Nucleic acid drugs; 2â²-O-Methylribonucleosides; Transribosylation; Nucleoside hydrolase; Agromyces;
Enzymatic synthesis of 2â²-O-methylribonucleosides with a nucleoside hydrolase family enzyme from Lactobacillus buchneri LBK78
Keywords: هیدرولاز نوکلئوزید; Nucleic acid drugs; 2â²-O-Methylribonucleosides; Transribosylation; Nucleoside hydrolase; Lactobacillus buchneri;
CD11a and CD49d enhance the detection of antigen-specific T cells following human vaccination
Keywords: هیدرولاز نوکلئوزید; Adjuvant; Protective immunity; Visceral leishmaniasis; T cell response; Activation markers; SE; squalene oil-in-water emulsion; GLA; glucopyranosyl lipid A adjuvant; MPL; monophosphoryl lipid A; NH; nucleoside hydrolase; SMT; sterol 24-c-methyltransferase
Combined virtual screening, MMPBSA, molecular docking and dynamics studies against deadly anthrax: An in silico effort to inhibit Bacillus anthracis nucleoside hydrolase
Keywords: هیدرولاز نوکلئوزید; Bacillus anthracis; Nucleoside hydrolase; Molecular docking and dynamics;
Characterization of inosine-uridine nucleoside hydrolase (RihC) from Escherichia coli
Keywords: هیدرولاز نوکلئوزید; BICINE; N,N-bis(2-hydroxyethyl)glycine; BSA; bovine serum albumin; CHES; 2-(cyclohexylamino)ethanesulfonic acid; CU-NH; cytidine-uridine nucleoside hydrolase; HEPES; N-(2-hydroxyethyl)piperazine-Nâ²-4-butanesulfonic acid); IAG-NH; inosine-adenosine-g
Structure ReportCrystal structure of the effector protein XOO4466 from Xanthomonas oryzae
Keywords: هیدرولاز نوکلئوزید; T3SS; type III secretion system; Xop; Xanthomonas outer protein; NH; nucleoside hydrolase; PCR; polymerase chain reaction; TEV; tobacco etch virus; DTT; dithiothreitol; PEG; polyethylene glycol; CU-NH; cytidine and uridine-specific nucleoside hydrolase; I
Biochemical characterization of recombinant nucleoside hydrolase from Mycobacterium tuberculosis H37Rv
Keywords: هیدرولاز نوکلئوزید; Mycobacterium tuberculosis; Nucleoside hydrolase; Substrate specificity; Thermodynamics; pH-rate profile; Spectrofluorimetry;
Kinetics and docking studies of two potential new inhibitors of the nucleoside hydrolase from Leishmania donovani
Keywords: هیدرولاز نوکلئوزید; Nucleoside hydrolase; Leishmania donovani; Leishmaniasis; Enzyme inhibitor; NMR; Molecular dockingNH, nucleoside hydrolase; LdNH, nucleoside hydrolase of Leishmania donovani; UV, ultraviolet; rLdNH, recombinant nucleoside hydrolase of Leishmania donovani;
N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase
Keywords: هیدرولاز نوکلئوزید; Nucleoside hydrolase; Purine-specific; Inhibitor; Antiparasitic
Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors
Keywords: هیدرولاز نوکلئوزید; Nucleoside hydrolase; Inhibitor; Cation–π-stacking interactions; Guanidino-alkyl-ribitol
Construction of a Saccharomyces cerevisiae strain expressing the Leishmania major nucleoside hydrolase gene
Keywords: هیدرولاز نوکلئوزید; Leishmania major; Nucleoside hydrolase; Drug screening; Leishmaniasis
Examination of the mechanism and energetic contribution of leaving group activation in the purine-specific nucleoside hydrolase from Trypanosoma vivax
Keywords: هیدرولاز نوکلئوزید; NH; nucleoside hydrolase; TvNH; nucleoside hydrolase from Trypanosoma vivax; CfNH; nucleoside hydrolase from Crithidia fasciculata; TbbNH; nucleoside hydrolase from Trypanosoma brucei brucei; pNPR; p-nitrophenylriboside; Guo; guanosine; Ino; inosine; NP;
Impact of quorum sensing on fitness of Pseudomonas aeruginosa
Keywords: هیدرولاز نوکلئوزید; Pseudomonas aeruginosa; Quorum sensing; N-acyl-homoserine lactones; S-adenosyl-methionine; Nucleoside hydrolase; Cell death; Stationary phase
Immunotherapy against visceral leishmaniasis with the nucleoside hydrolase-DNA vaccine of Leishmania donovani
Keywords: هیدرولاز نوکلئوزید; Immunotherapy; Visceral leishmaniasis; Murine leishmaniasis; Nucleoside hydrolase; Allium sativum
Transition-state Complex of the Purine-specific Nucleoside Hydrolase of T. vivax: Enzyme Conformational Changes and Implications for Catalysis
Keywords: هیدرولاز نوکلئوزید; nucleoside hydrolase; transition-state analogue; crystal structure; loop movement; leaving group activationNH, nucleoside hydrolase; PNP, purine nucleoside phosphorylase; PRT, phosphoribosyl transferase; IAG-NH, inosine-adenosine-guanosine preferring nucl
Purification and characterization of RihC, a xanthosine-inosine-uridine-adenosine-preferring hydrolase from Salmonella enterica serovar Typhimurium
Keywords: هیدرولاز نوکلئوزید; Nucleoside hydrolase; Xanthosine metabolism; Purine salvage pathway; pH dependence; Salmonella typhimurium;
Encapsulation of therapeutic nucleoside hydrolase in functionalised nanocapsules
Keywords: هیدرولاز نوکلئوزید; Nanoreactor; Liposomes; Bacterial porins; Nucleoside hydrolase; Encapsulation;
Kinetic isotope effects of nucleoside hydrolase from Escherichia coli
Keywords: هیدرولاز نوکلئوزید; LC/MS; liquid chromatography/mass spectrometry; IU-NH; inosine/uridine nucleoside hydrolase; GI-NH; guanosine/inosine preferring nucleoside hydrolase; KIE; kinetic isotope effects; LB; Luria-Bertani; IPTG; isopropyl β-d-thiogalactopyranoside; Tris;