Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; HIV; human immunodeficiency virus; RT; reverse transcriptase; NNRTI; non-nucleoside reverse transcriptase inhibitor; NRTI; nucleoside reverse transcriptase inhibitor; WT; wild-type; K101P; Lysine101Proline; IC50; inhibition concentration at 50%; EC50; eff
مقالات ISI مهار کننده ترانس کپیکول معکوس نوکلئوزید (ترجمه نشده)
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Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; 3TC; lamivudine; ABC; abacavir; ACN; acetonitrile; aCSF; artificial cerebrospinal fluid; CNS; central nervous system; CSF; cerebrospinal fluid; ER; extraction recovery; ESI; electrospray ionization; FA; formic acid; FTC; emtricitabine; FWHM; full width at
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; AIDS; acquired immune deficiency syndrome; ALV; avian leukosis virus; AMV; avian myeloblastosis virus; APOBEC; apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like; ASLV; avian sarcoma leukosis virus; AZT; 3â² -azido-3â² -deoxythymidine; BIV;
Effect of dolutegravir in combination with Nucleoside Reverse Transcriptase Inhibitors (NRTIs) on people living with HIV who have pre-existing NRTI mutations
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; HIV-1; Antiretroviral therapy; Nucleoside reverse transcriptase inhibitor; NRTI; Resistance; Dolutegravir;
Optimization of tenofovir release from mucoadhesive vaginal tablets by polymer combination to prevent sexual transmission of HIV
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; ACDP; anhydrous calcium hydrogen phosphate; AIDS; acquired immunodeficiency syndrome; AUC0âtâ; area under the curve between time 0 and complete erosion; CH; chitosan; Dp; mean pore sizes; ERS; Eudragit® RS; FE-SEM; field-emission scanning electron mi
HIV-1 integrase inhibitor resistance among treatment naïve patients in the West of Scotland
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; PI; protease inhibitor; NRTI; nucleoside reverse transcriptase inhibitor; NNRTI; non-nucleoside reverse transcriptase inhibitor; HAART; highly active anti-retroviral therapy; TDR; transmitted drug resistance; IDU; injecting drug user; MSM; men who have se
Tenofovir alafenamide (TAF) does not deplete mitochondrial DNA in human T-cell lines at intracellular concentrations exceeding clinically relevant drug exposures
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; Mitochondrial toxicity; mtDNA synthesis; T-cells; NRTI; TAF; Tenofovir alafenamide; d4T; stavudine; ddC; dideoxycytidine; ddI; dideoxyinosine; NRTI; nucleoside reverse transcriptase inhibitor; PBMC; peripheral blood mononuclear cell; TAF; tenofovir alafen
Azidothymidine-triphosphate impairs mitochondrial dynamics by disrupting the quality control system
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; ATP; adenosine triphosphate; AZT; 3ê-azido-3ê-deoxythymidine; AZT-DP; AZT diphosphate; AZT-MP; AZT monophosphate; AZT-TP; AZT-triphosphate; calcein-AM; calcein acetoxymethyl ester; cDNA; complementary DNA; DHE; dihydroethidium; DMEM; Dulbecco's Modifi
Polymorphisms in DNA polymerase γ affect the mtDNA stability and the NRTI-induced mitochondrial toxicity in Saccharomyces cerevisiae
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; d4T; 3â²-deoxy-2â²,3â²-didehydrothymidine or stavudine; ddC; 2â²,3â²-dideoxycytidine or zalcitabine; Ed4T; 2â²,3â²-didehydro-3â²-deoxy-4â²-ethynylthymidine; EryR; resistant to erythromycin; exo; exonuclease; FLT; 3â²-fluoro-3â²-deoxythymidine;
A qualitative PCR minipool strategy to screen for virologic failure and antiretroviral drug resistance in South African patients on first-line antiretroviral therapy
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; ART; antiretroviral therapy; WHO; World Health Organisation; PI; protease inhibitor; DBS; dried blood spot; ADR; antiretroviral drug resistance; NHLS; National Health Laboratory Service; RT; Reverse Transcriptase Coding Region of Pol Gene; NNRTI; non-nucl
Expression of ATP-binding cassette membrane transporters in a HIV-1 transgenic rat model
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; ARVs; antiretroviral drugs; ABC; ATP-binding cassette; BBB; blood-brain barrier; Bcrp/BCRP; breast cancer resistance protein; CNS; central nervous system; GSH; glutathione; GSSG; glutathione disulfide gp120, HIV-1 glycoprotein-120; HIV; human immunodefi
Neutrophils in antiretroviral therapy-controlled HIV demonstrate hyperactivation associated with a specific IL-17/IL-22 environment
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; Neutrophils; HIV; inflammation; IL-18; IL-17; IL-22; 7-AAD; 7-Amino-actinomycin D; APC; Allophycocyanin; ART; Antiretroviral therapy; FITC; Fluorescein isothiocyanate; HC; Healthy control subject; HIV(I); HIV-infected patients with inflammatory diseases;
Evaluation of the automatic editing tool RECall for HIV-1 pol and V3 loop sequences
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; AA; amino acid; ART; antiretroviral therapy; env; envelope gene; EQA; external quality assessment; FPR; false positive rate; HIV-1; human immunodeficiency virus type 1; NNRTI; non-nucleoside reverse transcriptase inhibitor; NRTI; nucleoside reverse transc
5,6-Dihydro-5-aza-2â²-deoxycytidine potentiates the anti-HIV-1 activity of ribonucleotide reductase inhibitors
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; 5-AZC; 5-azacytidine; dFdC; 2â²,2â²-difluoro-2â²-deoxycytidine; dFdU; 2â²,2â²-difluoro-2â²-deoxyuridine; DMSO; dimethylsulfoxide; KP-1212; 5-aza-5,6,-dihydro-2â²-deoxycytidine; MOI; multiplicity of infection; NRTI; nucleoside reverse transcriptase
Comparative analysis of genetic toxicity of antiretroviral combinations in somatic cells of Drosophila melanogaster
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; NRTI; nucleoside reverse transcriptase inhibitor; HAART; highly active antiviral therapy; AZT; 3â²-azido-3â²-deoxythymidine; ddI; 2â²,3â²-dideoxyinosine; 3TC; [â] 2â²-deoxy-3â²-thiacytidine; d4T; 3â²-deoxy-2â²,3â²-didehydrothymidine; SMART; som
Development and validation of an assay for the simultaneous determination of zidovudine, abacavir, emtricitabine, lamivudine, tenofovir and ribavirin in human plasma using liquid chromatography–tandem mass spectrometry
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; HIV; HCV; HBV; Nucleoside reverse transcriptase inhibitor; Nucleotide reverse transcriptase inhibitor; Bioanalysis
Challenging the catechism of therapeutics for chronic neuropathic pain: Targeting CaV2.2 interactions with CRMP2 peptides
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; CGRP; calcitonin gene related peptide; CaV2.2; N-type voltage-gated Ca2+ channel; CBD; Ca2+ channel binding domain; CRMP2; collapsin response mediator protein 2; CPP; cell penetrating peptide; CNS; central nervous system; Ï-CTX; omega-conotoxin; DIV; day
Development and evaluation of an assay for HIV-1 protease and reverse transcriptase drug resistance genotyping of all major group-M subtypes
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; ART; antiretroviral therapy; DBS; dried blood spot; LOD; limit of detection; NNRTI; non-nucleoside reverse transcriptase inhibitor; NRTI; nucleoside reverse transcriptase inhibitor; Nt; nucleotide; PI; protease inhibitor; PMTCT; prevention-of-mother-to-ch
High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; ART; antiretroviral therapy; CI; confidence interval; NRTI; nucleoside reverse transcriptase inhibitor; NNRTI; non-nucleoside RTI; PI; protease inhibitor; FCR; full-class resistance; CRF; circulating recombinant form; HIV; human immunodeficiency virus; MD
In vitro supplementation with deoxynucleoside monophosphates rescues mitochondrial DNA depletion
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; COX; cytochrome c oxidase; COX II; cytochrome c oxidase subunit II; DGUOK; deoxyguanosine kinase; dNMP; deoxy-nucleoside monophosphate; dNDP; deoxy-nucleoside diphosphate; dNTP; deoxy-nucleoside triphosphate; HIV; human immunodeficiency virus; HRP; horser
Profile of stress and toxicity gene expression in human hepatic cells treated with Efavirenz
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; EFV; Efavirenz; HAART; highly active antiretroviral therapy; NRTI; nucleoside reverse transcriptase inhibitor; NNRTI; non-nucleoside reverse transcriptase inhibitor; ROS; reactive oxygen species; ÎΨm; mitochondrial transmembrane potential; DNA; polymera
Antiviral therapies: Focus on hepatitis B reverse transcriptase
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; HBV; Hepatitis B virus; HBsAg; HBV surface antigen; HBeAg; HBV e antigen; RT; reverse transcriptase; NRTI; nucleoside reverse transcriptase inhibitor; LVD/3TC; lamivudine; ADV; adefovir dipivoxil; ETV; entecavir; LdT; telbivudine; TDF; tenofovir disoproxi
Synthesis and anti-HIV activity of 2â²-deoxy-2â²-fluoro-4â²-C-ethynyl nucleoside analogs
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; HIV-1; human immunodeficiency virus type-1; RT; reverse transcriptase; NRTI; nucleoside reverse transcriptase inhibitor; NNRTI; non-nucleoside reverse transcriptase inhibitor; dN; 2â²-deoxynucleoside; ddN; 2â²,3â²-dideoxynucleoside; AZT; zidovudine; SA
Prevalence and Factors Associated With Liver Test Abnormalities Among Human Immunodeficiency Virus-Infected Persons
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BMI; body mass index; HAART; highly active antiretroviral therapy; HDL; high-density lipoprotein; HIV; human immunodeficiency virus; IQR; interquartile range; LDL; low-density lipoprotein; NA
Lateral-flow immunoassay for detecting drug-induced inhibition of mitochondrial DNA replication and mtDNA-encoded protein synthesis
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; mtDNA; mitochondrial DNA; NRTI; nucleoside reverse transcriptase inhibitor; PBS; phosphate buffered saline; HEPES; 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid; SDS-PAGE; sodium dodecyl sulfate polyacrylamide gel electrophoresis; Ab; antibody; mAb;
Drug-induced paraparotid fat deposition in patients with HIV
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; Paraparotid fat; lipodystrophy; lipodystrophy syndrome; highly active antiretroviral therapy; CT; Computed tomography; DILS; Diffuse infiltrative CD8 lymphocytosis syndrome; HAART; Highly active antiretroviral therapy; LD; Lipodystrophy; LDS; Lipodystroph
Increased incidence of asthma in HIV-infected children treated with highly active antiretroviral therapy in the National Institutes of Health Women and Infants Transmission Study
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; Pediatric HIV infection; CD4+ T cell-mediated induction of asthma; highly active antiretroviral therapy-produced immunoreconstitution; ART; Antiretroviral therapy; GEE; Generalized estimating equation; HAART; Highly active antiretroviral therapy; NNRT
An age-dependent association of mannose-binding lectin-2 genetic variants on HIV-1-related disease in children
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; Mannose binding lectin-2; polymorphisms; HIV-1 disease; central nervous system impairment; children; CNS; Central nervous system; MBL; Mannose-binding lectin; MBL2; Mannose binding lectin-2; NRTI; Nucleoside reverse transcriptase inhibitor; PACTG; Pediatr
Hyperbilirubinemia in the setting of antiviral therapy
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; AIDS; acquired immunodeficiency syndrome; CMV; cytomegalovirus; HIV; human immunodeficiency virus; MRP2; multidrug resistance-associated protein 2; NIAID; National Institute of Allergy and Infectious Diseases; NRTI; nucleoside reverse transcriptase inhibi
Activity profiles of deoxynucleoside kinases and 5â²-nucleotidases in cultured adipocytes and myoblastic cells: insights into mitochondrial toxicity of nucleoside analogs
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; AZT; 3â²-azido-2â²,3â²-dideoxythymidine; cN-1b; cytosolic 5â²-nucleotidase 1b; cN-2; cytosolic 5â²-nucleotidase; dCK; deoxycytidine kinase; dGK; deoxyguanosine kinase; DMEM; Dubelcco's modified Eagle's medium; DNC; deoxynucleotide carrier; dNK; deoxy
Assessment of drug resistance mutations in plasma and peripheral blood mononuclear cells at different plasma viral loads in patients receiving HAART
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; HIV-1; human immunodeficiency virus type 1; HAART; highly active antiretroviral therapy; PBMC; peripheral blood mononuclear cells; BDL; below detectable level; Pr; protease; RT; reverse transcriptase; PI; protease inhibitor; NRTI; nucleoside reverse trans
Site specific alterations of adipose tissue mitochondria in 3â²-azido-3â²-deoxythymidine (AZT)-treated rats: An early stage in lipodystrophy?
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; AUC; area under the curve; AZT; 3â²-azido-3â²-deoxythymidine; CCCP; carbonyl cyanide m-chlorophenylhydrazone; GPx; glutathione peroxidase; HAART; highly active anti retroviral therapy; MDA; malondialdehyde; mt DNA; mitochondrial DNA; nDNA; nuclear D
Loading efficiency of stavudine on polybutylcyanoacrylate and methylmethacrylate-sulfopropylmethacrylate copolymer nanoparticles
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; D4T; stavudine; HIV; human immunodeficiency virus; LE; loading efficiency (%); MMA-SPM; methylmethacrylate-sulfopropylmethacrylate; NP; nanoparticle; NRTI; nucleoside reverse transcriptase inhibitor; PBCA; polybutylcyanoacrylate; PDI; polydispersity index
Crystallography and the design of anti-AIDS drugs: conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase inhibitors
Keywords: مهار کننده ترانس کپیکول معکوس نوکلئوزید; Dapivirine; TMC120-R147681; Drug design; Drug resistance; Etravirine; TMC125-R165335; 3DSAR; Three-dimensional structure-activity relationships; DAPY; Diarylpyrimidine; DATA; Diaryltriazine; dsDNA; Double-stranded DNA; HAART; Highly active antiretroviral