دانلود مقالات ISI درباره Oligodeoxynucleotide + ترجمه فارسی

مکانیسم عمل، فارماکوکینتیک، اثربخشی و ایمنی داروهای ترانسفرالری با استفاده از اتیولوژی نفت: بررسی پیش از موعد در مدل های سرطان کبد

Mechanism of Action, Pharmacokinetics, Efficacy, and Safety of Transarterial Therapies Using Ethiodized Oil: Preclinical Review in Liver Cancer Models

Keywords: DEE; drug-eluting embolic; FdUrd-C8; 3′,5′-dioctanoyl-5-fluoro-2′-deoxyuridine; HCC; hepatocellular carcinoma; IL; interleukin; LRT; locoregional therapy; MN-16ET; N-[2-(triphenylmethyl)thioethyl]-3-aza-19-ethyloxycarbonyl-3-[2-(triphenylmethyl)thio

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

سلولهای دندریتیک پلاسماییکوئیدی در حال افزایش حوادث آسم هستند

Plasmacytoid dendritic cells drive acute asthma exacerbations

Keywords: Plasmacytoid dendritic cells; asthma; animal models of allergic airway disease; rhinovirus; asthma exacerbations; AAD; Allergic airway disease; BAL; Bronchoalveolar lavage; BDCA-2; Blood dendritic cell antigen 2; CRLF2; Cytokine receptor-like factor 2;

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

گیرنده های پولی مانند و نقش آنها در درد مداوم

Toll-like receptors and their role in persistent pain

Keywords: AP-1; activator protein-1; ATP; adenosine triphosphate; BDNF; brain-derived neurotrophic factor; CCI; chronic constriction injury; CCL2; chemokine C-C motif ligand 2; CCL21; chemokine C-C motif ligand 21; CD11b; cluster of differentiation 11b; CD14; clust

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2018 سفارش ترجمه

تکنولوژی فاکتور رونویسی: تکنولوژی به روز رسانی درمانی

Transcription factor decoy technology: A therapeutic update

Keywords: AAV; adeno-associated virus; E2F; E2 transcription factor; FOXO3; Forkhead box protein O3; Nanog; Nanog homeobox transcription factor; NF-κB; nuclear factor-κB; Oct; octamer-binding protein; ODN; oligodeoxynucleotide; Sox; Sox transcription factor (refe

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

توسعه یک سیستم واکسن سرطان سگ سلولی برای تومورهای بدخیم قابل تنظیم در سگ ها

Development of an autologous canine cancer vaccine system for resectable malignant tumors in dogs

Keywords: ADCC; antibody-dependent cellular cytotoxicity; Ag; antigen; APC; antigen-presenting cell; DC; dendritic cells; K9-ACV; autologous canine cancer vaccine; LAL; limulus amebocyte lysate; NSCLC; non-small cell lung cancer; ODN; oligodeoxynucleotide; PAGE; po

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

تعامل بین پپتیدهای ضد میکروبی و میکوباکتریوم

Interaction between antimicrobial peptides and mycobacteria

Keywords: TB; tuberculosis; Mtb; Mycobacterium tuberculosis; AMP; antimicrobial peptide; PG; peptidoglycan; AG; arabinogalactan; MM; mycomembrane; TDM; trehalose dimycolate; TMM; trehalose monomycolate; PIM; phosphatidylinositol-mannosides; PDIM; phthiocerol dimyco

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

پشتیبانی از لغو مقررات آزمون ایمنی عمومی در برنامه های کاربردی مجوز بیولوژیک

Support for the revocation of general safety test regulations in biologics license applications

Keywords: Safety; CpG; Oligodeoxynucleotide; Pharmacology; Vaccine; Adjuvant

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Quantitative assessment of HR and NHEJ activities via CRISPR/Cas9-induced oligodeoxynucleotide-mediated DSB repair

Keywords: CRISPR/Cas9; Oligodeoxynucleotide; DNA double-strand break; Homologous recombination; Non-homologous end joining; DNA repair;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Development of orally-deliverable DNA hydrogel by microemulsification and chitosan coating

Keywords: CpG; cytosine-phosphate-guanine; ODN; oligodeoxynucleotide; Dgel-MS; DNA hydrogel microsphere; Cs-Dgel; chitosan-coated DNA hydrogel; Cs-Dgel-MS; chitosan-coated DNA hydrogel microsphere; mDgel; modified DNA hydrogel; TLR9; Toll-like receptor 9; Polypodna

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Long-lasting ameliorating effects of the oligodeoxynucleotide IMT504 on mechanical allodynia and hindpaw edema in rats with chronic hindpaw inflammation

Keywords: Pain; Allodynia; Rats; Oligodeoxynucleotide; Systemic; Inflammation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

AKT1 distinctively suppresses MyD88-depenedent and TRIF-dependent Toll-like receptor signaling in a kinase activity-independent manner

Keywords: TLR; Toll-like receptor; TRIF; Toll/IL-1R domain-containing adaptor inducing IFN-β; LPS; lipopolysaccharide; KD; kinase-dead; IRAK; IL-1R-associated kinase; ISG; interferon stimulated gene; PIP3; phosphatidylinositol (3,4,5) trisphosphate; PH; pleckstrin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Zinc deficiency promotes cystitis-related bladder pain by enhancing function and expression of Cav3.2 in mice

Keywords: AS; distinct antisense; CPA; cyclophosphamide; CSE; cystathionine-γ-lyase; DRG; dorsal root ganglia; Egr-1; early growth response-1; ODN; oligodeoxynucleotide; REST; repressor element-1 silencing transcription factor; SC-ODN; control scrambled ODN; TPEN;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Signal management in pharmacovigilance and human risk assessment of CpG 7909, integrating embryo-fetal and post-natal developmental toxicity studies in rats and rabbits

Keywords: BW; body weight; CpG; unmethylated 2′ deoxyribo (cytidine-phosphate-guanosine); EFD; embryo-fetal development; EMA; European Medicines Agency; FDA; Food and Drug Administration; G0; day 0 of gestation; GSK; GlaxoSmithKline; HLS; Huntington Life Sciences

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Vaccination with the polymorphic membrane protein A reduces Chlamydia muridarum induced genital tract pathology

Keywords: DDA/MPL; dimethyldioctadecylammonium bromide/monophosphoril lipid A; MOMP; major outer membrane protein; Mon-CpG; Montanide ISA 720/CpG-ODN 1826; ODN; oligodeoxynucleotide; Pmp; polymorphic membrane protein; TH1; T-helper 1; Chlamydia muridarum; Genital t

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Effects of phosphodiester and phosphorothioate ODN2216 on leukotriene synthesis in human neutrophils and neutrophil apoptosis

Keywords: Oligodeoxynucleotide; Neutrophil; 5-Lipoxygenase; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Role of TLR gene expression and cytokine profiling in the immunopathogenesis of viral hepatitis E

Keywords: AVH; acute viral hepatitis; ALF; acute liver failure; CTLs; cytotoxic T lymphocytes; DCs; dendritic cells; HEV; hepatitis E virus; MODS; multiple organ dysfunction syndromes; ODN; oligodeoxynucleotide; ORF2; open reading frame 2; PBMCs; peripheral blood m

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Systemic immune responses to an inactivated, whole H9N2 avian influenza virus vaccine using class B CpG oligonucleotides in chickens

Keywords: Toll-like receptor 21; Low pathogenic avian influenzavirus; H9N2 subtype; CpG oligodeoxynucleotides; Chickens; Antibody response; Haemagglutination inhibition; Virus neutralization; ELISA; TLR; Toll-like receptor; ODN; oligodeoxynucleotide; CpG ODN; ODN c

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Grafting of oligodeoxynucleotide hairpin onto membrane surface to improve its anti-fouling performance

Keywords: Polyacrylonitrile; Oligodeoxynucleotide; Hairpin; Anti-fouling; Ultrafiltration

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The anti-inflammatory effects of a high-frequency oligodeoxynucleotide from the genomic DNA of Lactobacillus casei

Keywords: Anti-inflammatory effect; Heat shock protein; Lactobacillus casei; Oligodeoxynucleotide; Toll-like receptor 9

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Human DExD/H RNA helicases: Emerging roles in stress survival regulation

Keywords: 5′ppp; 5′ triphosphate; AMD; ARE-mediated mRNA decay; ARE; AU-rich element; ARE-BP; ARE-binding protein; CARD; caspase activation and recruitment domain; CCCP; carbonyl cyanide m-chlorophenyl hydrazone; CDN; cyclic dinucleotide; CRM1; Chromosome Maint

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

TET enzymatic oxidation of 5-methylcytosine, 5-hydroxymethylcytosine and 5-formylcytosine

Keywords: α-KG; α-ketoglutarate; AML; acute myeloid leukemia; APOBEC; apolipoprotein B mRNA-editing enzyme complex; ARP; aldehyde reactive probe; β-GT; β-glucosyl transferase; 5-caC; 5-carboxylcytosine; 5-cadCyd; 5-carboxyl-2′-deoxycytidine; C; cytosine; C5-M

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2014 سفارش ترجمه

Protein kinase C-dependent activation of CaV1.2 channels selectively controls human TH2-lymphocyte functions

Keywords: Chemoattractant receptor-homologous molecule expressed on TH2 cells; asthma; calcium; voltage-dependent calcium channels; TH2 cytokines; protein kinase C α/β; AS; Antisense; [Ca]i; Intracellular calcium concentration; Cav1; Voltage-dependent calcium cha

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2014 سفارش ترجمه

Recognition of CpG oligodeoxynucleotides by human Toll-like receptor 9 and subsequent cytokine induction

Keywords: TLR; Toll-like receptor; hTLR9; human toll-like receptor 9; mTLR9; mouse toll-like receptor 9; CpG; cytosine-phosphate-guanine; ODN; oligodeoxynucleotide; PTO; phosphorothioate; PD; phosphodiester; ECD; extracellular domain; LRR; leucine rich repeat;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Effects of colchicine-induced microtubule depolymerization on TRPV4 in rats with chronic compression of the dorsal root ganglion

Keywords: DRG; dorsal root ganglion; CCD; chronic compression of the dorsal root ganglion; TRPV4; transient receptor potential vanilloid subtype 4; ODN; oligodeoxynucleotide; CCI; loose ligation of the sciatic nerve; Colchicine; Microtubule depolymerization; Allody

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis of novel chitosan–silica/CpG oligodeoxynucleotide nanohybrids with enhanced delivery efficiency

Keywords: Nanohybrids; Oligodeoxynucleotide; Cellular uptake; Cytokines

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

A practical post-modification synthesis of oligodeoxynucleotides containing 4,7-diaminoimidazo[5′,4′:4,5]pyrido[2,3-d]pyrimidine nucleoside

Keywords: Nucleoside; Imidazopyridopyrimidine; Oligodeoxynucleotide; Post-modification synthesis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Sexual responses of the male rat medial preoptic area and medial amygdala to estrogen I: Site specific suppression of estrogen receptor alpha

Keywords: Antisense; Aromatase; Copulatory behavior; ERα; ERβ; Estradiol; Mating; Oligodeoxynucleotide; Sexual behavior; Testosterone;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

CpG-containing oligodeoxynucleotides increases resistance of Anopheles mosquitoes to Plasmodium infection

Keywords: CpG; Oligodeoxynucleotide; Immunity; Malaria; Mosquito; Transglutaminase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: The involvement of cannabinoid system

Keywords: Euphol; CB1 and CB2 cannabinoid receptor; Cytokines/chemokines; Inflammatory and neuropathic persistent pain; euphol; eupha-8,24-dien-3β-ol; CB; cannabinoid; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; AS; antisense; ODN; oligodeo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

An oligodeoxynucleotide capable of lessening acute lung inflammatory injury in mice infected by influenza virus

Keywords: Influenza virus; Infection; Acute lung inflammatory injury; Oligodeoxynucleotide; Therapy;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

The role of IL-21 in hematological malignancies

Keywords: IL-21; interleukin-21; rIL-21; recombinant IL-21; IL-21R; IL-21 receptor; JAK/STAT; Janus-activated kinase/signal transducer and activator of transcription; CpG; cytosine-phosphate-guanosine; ODN; oligodeoxynucleotide; anti-BCR; anti-B-cell-receptor antib

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and characterization of oligodeoxynucleotides containing a novel tetraazabenzo[cd]azulene:naphthyridine base pair

Keywords: Tetraazabenzo[cd]azulene; Hydrogen bond; Nucleobase; Nucleoside; Oligodeoxynucleotide;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Effects of oligodeoxynucleotide with CCT repeats on chronic graft versus host disease induced experimental lupus nephritis in mice

Keywords: Chronic graft versus host disease; Lupus nephritis; Toll-like receptors; Oligodeoxynucleotide; Therapy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Stoichiometry-focused 18F-labeling of alkyne-substituted oligodeoxynucleotides using azido([18F]fluoromethyl)benzenes by Cu-catalyzed Huisgen reaction

Keywords: PET; positron emission tomography; ODN; oligodeoxynucleotide; SPE; solid phase extraction; TBTA; tris((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)amine; DCY; decay-corrected radiochemical yield; DOTA; 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid; T

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Increase in CpG DNA-induced inflammatory responses by DNA oxidation in macrophages and mice

Keywords: CpG motif; unmethylated CpG dinucleotide; TLR; Toll-like receptor; LPS; lipopolysaccharide; ROS; reactive oxygen species; RA; rheumatoid arthritis; mtDNA; mitochondrial DNA; nDNA; nuclear DNA; ODN; oligodeoxynucleotide; PO; phosphodiester; PS; phosphoroth

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Marked enhancement of the immune response to BioThrax® (Anthrax Vaccine Adsorbed) by the TLR9 agonist CPG 7909 in healthy volunteers

Keywords: BioThrax; Anthrax Vaccine Adsorbed; CPG 7909; CpG; Oligodeoxynucleotide; Clinical trial; Adjuvant;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Investigation of the reactivity of oligodeoxynucleotides with glyoxal and KMnO4 chemical probes by electrospray ionization mass spectrometry

Keywords: Electrospray ionization; Chemical probe; Nucleic acid; Oligodeoxynucleotide; Glyoxal; Guanine;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice

Keywords: Nonalcoholic Fatty Liver Diseases; Toll-Like Receptors; Bacterial DNA; Bambi; ALT; alanine transaminase; ATP; adenosine triphosphate; CDAA; choline-deficient amino-acid defined; CpG; cytosine phosphate guanine; CSAA; choline-supplemented amino acid define

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2010 سفارش ترجمه

Selective fluorescence quenching of the 8-oxoG-clamp by 8-oxodeoxyguanosine in ODN

Keywords: 2′-Deoxy-8-oxoguanosine; Fluorescence; Detection; 8-OxoG-clamp; Oligodeoxynucleotide

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Simultaneous recognition of nucleobase and sites of DNA damage: Effect of tethered cation on the binding affinity

Keywords: DCPC-NH2; 3,5-diamino-N-(3-aminopropyl)-6-chloropyrazine-2-carboxamide; DCPC; 3,5-diamino-6-chloro-2-pyrazinecarbonitrile; AP; abasic; SNP; single nucleotide polymorphism Spacer C3, Spacer phosphoramidite C3; ODN; oligodeoxynucleotide; Single nucleotide p

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

TLR-9 signaling and TCR stimulation co-regulate CD8+ T cell-associated PD-1 expression

Keywords: M27L; human MelanA26-3(27L) peptide; MART-1; melanoma antigen recognized by T cells-1; ODN; oligodeoxynucleotide; Vaccination; Adjuvant; T cells; Antigen; Costimulation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Human microsatellite DNA mimicking oligodeoxynucleotides down-regulate TLR9-dependent and -independent activation of human immune cells

Keywords: CpG ODN; Oligodeoxynucleotide containing unmethylated CpG motif; Cy3-MS08; Cy3-labeled MS08; FITC-BW006; FITC-labeled BW006; 3H-TdR; 3H-thymidine; IMDM; Iscove's Modified Dulbecco's Medium; MAPK; mitogen activated protein kinases; MFI; mean fluorescence i

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Anthracene based base-discriminating fluorescent oligonucleotide probes for SNPs typing: Synthesis and photophysical properties

Keywords: BDF; SNP typing; Oligodeoxynucleotide; Fluorescence

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Resolution of the EcoRII restriction endonuclease-DNA complex structure in solution using fluorescence spectroscopy

Keywords: REase; restriction endonuclease; EMSA; electrophoretic mobility shift assay; ON; oligodeoxynucleotide; FAM; 5(6)-carboxyfluorescein; TAMRA; 5(6)-carboxytetramethylrhodamine; FRET; fluorescence resonance energy transfer; СDNA; DNA concentration; EcoRII en

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Suppression of HUVEC tissue factor synthesis by antisense oligodeoxynucleotide

Keywords: Tissue factor; Endothelial cells; Oligodeoxynucleotide; CD31; Receptor-mediated endocytosis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Application of six-color flow cytometry for the assessment of dendritic cell responses in whole blood assays

Keywords: PBDC; peripheral blood dendritic cell; WB; whole blood; TLR; toll-like receptor; mDC; myeloid DC; pDC; plasmacytoid DC; TNF; tumor-necrosis factor; IFN; interferon; PBMCs; peripheral blood mononuclear cells; poly(I:C); polyribosinoinic-polyribocytidylic

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Irradiation of Human Prostate Cancer Cells Increases Uptake of Antisense Oligodeoxynucleotide

Keywords: Radiation; Cancer; Antisense; Oligodeoxynucleotide; Fluorescent;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Identification and quantification of GC-rich oligodeoxynucleotides in tissue extracts by capillary gel electrophoresis

Keywords: CpG; Oligonucleotide; Capillary gel electrophoresis; GC-rich; Secondary-structure; ODN; oligodeoxynucleotide; ORN; oligoribonucleotide; siRNA; small interfering ribonucleic acid; CpG ODN; immunomodulatory oligodeoxynucleotide containing a CpG motif; C-Mix

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Lipoteichoic acid downregulates FcεRI expression on human mast cells through Toll-like receptor 2

Keywords: Mast cells; basophils; Fc receptors; allergy; β-hex; β-Hexosaminidase; ERK; Extracellular signal-regulated kinase; FITC; Fluorescein isothiocyanate; LTA; Lipoteichoic acid; MC; Mast cell; MFI; Mean fluorescence intensity; NP; Nitrophenylacetyl; ODN; O

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

A prospero-related homeobox gene Prox-1 is expressed during postnatal brain development as well as in the adult rodent brain

Keywords: embryonic transcription factors; Prox-1 homeobox gene; brain; postnatal development; rat; mouse; E; embryonic day; IHC; immunohistochemistry; IR; immunoreactivity; ISH; in situ hybridization; ODN; oligodeoxynucleotide; PBS; phosphate-buffered saline; PD;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه