Keywords: فسفولیپید های اکسید شده; atherosclerosis; interleukin; lipoprotein(a); oxidation; oxidized phospholipids;
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The interaction of phospholipase A2 with oxidized phospholipids at the lipid-water surface with different structural organization
Keywords: فسفولیپید های اکسید شده; PLA2; phospholipase A2; PC; phosphatidylcholine; Hb; hemoglobin; OxPCs; oxidized phosphatidylcholine; OxPLs; oxidized phospholipids; ROS; reactive oxygen species; LPO; lipid peroxidation; TAC; total antioxidant capacity; TAA; total antioxidant activity; D
OLR1 scavenger receptor knockdown affects mitotic gene expression but is dispensable for oxidized phospholipid- mediated stress signaling in SZ 95 sebocytes
Keywords: فسفولیپید های اکسید شده; Sebocyte; Oxidized phospholipids; OLR1; Receptor; Stress; NRF2;
Characterization of covalent modifications of HDL apoproteins by endogenous oxidized phospholipids
Keywords: فسفولیپید های اکسید شده; HNE; 4-hydroxy-2-nonenal; MDA; malondialdehyde; MPO; myeloperoxidase; LCAT; lecithin-cholesterol acyltransferase; AIPH; 2, 2'âazobis[2â(2âimidazolinâ2âyl)propane] dihydrochloride; BHT; butylated hydroxytoluene; MALDI-TOF MS; Matrix-assisted
Macrophages sensing oxidized DAMPs reprogram their metabolism to support redox homeostasis and inflammation through a TLR2-Syk-ceramide dependent mechanism
Keywords: فسفولیپید های اکسید شده; Oxidized phospholipids; Spleen tyrosine kinase; Macrophages; Bioenergetics; Cellular metabolism; Redox homeostasis; Inflammation; Ceramides;
Oxidized phospholipids exert a dual effect on bile acid-induced CCL2 expression in pancreatic acini
Keywords: فسفولیپید های اکسید شده; Inflammatory gene expression; Pancreatic acinar cells; PPARγ; Oxidized phospholipids; TLR4; CCL2; chemokine (C-C motif) ligand 2; FA; fatty acid; JAK; janus kinase; JNK-MAPK; c-Jun NH2-terminal kinase mitogen-activated protein kinase; NF-κB; nuclear fac
Dual signaling evoked by oxidized LDLs in vascular cells
Keywords: فسفولیپید های اکسید شده; AAPH; 2,2'-azobis(2-amidinopropane) dihydrochloride; AIF; apoptotic inducing factor; AMVN; 2,4-dimethylvaleronitrile; AP-1; activator protein 1; ATF6; activating transcription factor 6; CDE; clathrin-dependent endocytosis; CCL2; chemokine ligand 2 (or MCP
Lipoprotein(a)-cholesterol levels estimated by vertical auto profile correlate poorly with Lp(a) mass in hyperlipidemic subjects: Implications for clinical practice interpretation of Lp(a)-mediated risk
Keywords: فسفولیپید های اکسید شده; Lipoprotein(a); Lipoprotein(a)-cholesterol; VAP; Oxidized phospholipids; Niacin; HDL-Cholesterol;
Fluctuation of lysosomal phospholipase A2 in experimental autoimmune uveitis in rats
Keywords: فسفولیپید های اکسید شده; Experimental autoimmune uveitis; Lewis rats; Lysosomal phospholipase A2; Aqueous humor; Macrophages; Oxidized phospholipids; Oxidative stress;
Effect of therapeutic interventions on oxidized phospholipids on apolipoprotein B100 and lipoprotein(a)
Keywords: فسفولیپید های اکسید شده; Oxidized phospholipids; Lipoprotein(a); Niacin; Simvastatin; Ezetimibe; Statin; Diet;
The re-emergence of lipoprotein(a) in a broader clinical arena
Keywords: فسفولیپید های اکسید شده; apo; apolipoprotein; AS; aortic stenosis; CAVS; calcific aortic valve stenosis; CVD; cardiovascular disease; LDL; low-density lipoprotein; LDL-C; low-density lipoprotein cholesterol; Lp(a); lipoprotein(a); OMT; optimal medical therapy; OxPL; oxidized phos
The oxidized phospholipid PazePC promotes permeabilization of mitochondrial membranes by Bax
Keywords: فسفولیپید های اکسید شده; Apoptosis; Bax-protein; Calorimetry; Membranes; NMR; Oxidized phospholipids; Leakage
An overview of molecular dynamics simulations of oxidized lipid systems, with a comparison of ELBA and MARTINI force fields for coarse grained lipid simulations
Keywords: فسفولیپید های اکسید شده; Oxidized phospholipids; Molecular dynamics; Coarse-grained; Free energy; Water permeation; Lipid mixing;
Monocyte subset distribution in patients with stable atherosclerosis and elevated levels of lipoprotein(a)
Keywords: فسفولیپید های اکسید شده; Lipoprotein(a); Atherosclerosis; Coronary artery disease; Monocyte subsets; Oxidized phospholipids;
Does hydrogen bonding contribute to lipoperoxidation-dependent membrane fluidity variation? An EPR-spin labeling study
Keywords: فسفولیپید های اکسید شده; n-DSPPC; 1-palmitoyl-2-(n-doxylstearoyl)-phosphatidylcholine, with n = 5, 12, or 16; n-DSA; n-doxylstearic acid; 3-DC; 3-doxylcholestane; EPR; electron paramagnetic resonance; HILIC ESI-MS; hydrophilic interaction liquid chromatography electrospray ioni
MicroRNA miR-320a modulates induction of HO-1, GCLM and OKL38 by oxidized phospholipids in endothelial cells
Keywords: فسفولیپید های اکسید شده; Oxidized phospholipids; Electrophilic stress response; MicroRNA-320a; HO-1; GCLM; OKL38; NRF2; ARE; antioxidant response element; ECs; endothelial cells; ESR; electrophilic stress response; GCLM; glutathione cysteine ligase modifying subunit; HO-1; heme o
Pro-Inflammatory Interleukin-1 Genotypes Potentiate the Risk of Coronary Artery Disease and Cardiovascular Events Mediated by Oxidized Phospholipids and Lipoprotein(a)
Keywords: فسفولیپید های اکسید شده; atherosclerosis; genetic risk stratification; haplotype; IL-1; inflammation; lipoprotein(a); lipoproteins; oxidation; oxidized phospholipids; polymorphismapo, apolipoprotein; CAD, coronary artery disease; CI, confidence interval; HDL-C, high-density lipop
Lipoprotein(a)
Keywords: فسفولیپید های اکسید شده; Lipoprotein(a); Apolipoprotein(a); Atherosclerosis; Thrombosis; Oxidized phospholipids; Coronary heart disease; Genetics; Risk factors;
Design of a novel LOX-1 receptor antagonist mimicking the natural substrate
Keywords: فسفولیپید های اکسید شده; CTLD; C-type lectin-like domain; DiI; 1,1â²-dioctadecyl-3,3,3â²,3â²-tetramethyllindocarbocyanine perchlorate; HOBt; 1-hydroxybenzotriazole; LDL; low-density lipoprotein; LOX-1; lectin-like oxidized low-density lipoprotein receptor-1; ox-LDL; oxidized l
Determination of phospholipase activity of PAF acetylhydrolase
Keywords: فسفولیپید های اکسید شده; C6NBD PC; 1-palmitoyl-2-(7-nitrobenzoxadiazolyl)aminocaproyl phosphatidylcholine; DEACZ; 7-diethylaminocoumarin-3-carbonyl azide; DNGP; 1-decanoyl-2-(4-nitrophenylglutaryl) phosphatidylcholine; PAF; platelet-activating factor; PAF-AH; platelet-activating
Retinal pigment epithelium cells produce VEGF in response to oxidized phospholipids through mechanisms involving ATF4 and protein kinase CK2
Keywords: فسفولیپید های اکسید شده; oxidized phospholipids; RPE; angiogenesis; unfolded protein response; protein kinase CK2;
Inhibition of monocyte chemotaxis by VB-201, a small molecule lecinoxoid, hinders atherosclerosis development in ApoEâ/â mice
Keywords: فسفولیپید های اکسید شده; Chemotaxis; Inflammation; Lecinoxoids; Oxidized phospholipids; DC; dendritic cell; FACS; fluorescence-activated cell sorting; GPCR; G-protein coupled receptor; LDL; low density lipoprotein; MCP-1; monocyte chemotactic protein-1; OxPL; oxidized phospholipi
Oxidation-Specific Biomarkers and Risk of Peripheral Artery Disease
Keywords: فسفولیپید های اکسید شده; autoantibodies; biomarker; immune complex; lipoprotein (a); oxidized phospholipids; peripheral artery diseaseABI, ankle-brachial index; ApoB, apolipoprotein B-100–containing lipoproteins; ApoB-IC, apoB-immune complexes; BMI, body mass index; BSA, bovine s
Permissive role of miR-663 in induction of VEGF and activation of the ATF4 branch of unfolded protein response in endothelial cells by oxidized phospholipids
Keywords: فسفولیپید های اکسید شده; Oxidized phospholipids; Unfolded protein response; VEGF; microRNA-663; ATF4; OxPAPC; oxidized palmitoyl-arachidonoyl-phosphatidylcholine; UPR; unfolded protein response; miRNA; microRNA; ECs; endothelial cells; OxPLs; oxidized phospholipids;
The oxidized phospholipid PazePC modulates interactions between Bax and mitochondrial membranes
Keywords: فسفولیپید های اکسید شده; CD; circular dichroism; DSC; differential scanning calorimetry; IMM; inner mitochondrial membrane; MAS; magic angle spinning; MLVs; multilamellar vesicles; MOM; mitochondrial outer membrane; MOMP; mitochondrial outer membrane permeabilization; NMR; nuclea
Oxidized phospholipids impair pulmonary antibacterial defenses: Evidence in mice exposed to cigarette smoke
Keywords: فسفولیپید های اکسید شده; COPD; Macrophages; Oxidized phospholipids; Bacteria; Phagocytosis; Cigarette smoke;
Development of oxidized phosphatidylcholine isomer profiling method using supercritical fluid chromatography/tandem mass spectrometry
Keywords: فسفولیپید های اکسید شده; Supercritical fluid chromatography; Mass spectrometry; Oxidized phospholipids; Phosphatidylcholine
Lipid hydration and mobility: An interplay between fluorescence solvent relaxation experiments and molecular dynamics simulations
Keywords: فسفولیپید های اکسید شده; sn-1 acyl group; Laurdan; Oxidized phospholipids; DOTAP; Hofmeister; Polarizability; Transient Stokes shift; MD; molecular dynamics; Laurdan; 6-lauroyl-2-dimethylaminonaphthalene; TDFS; time-dependent fluorescence shift; SR; solvent relaxation; Patman;
Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL
Keywords: فسفولیپید های اکسید شده; Apolipoprotein M; HDL; Antioxidant; Oxidized phospholipids; Atherosclerosis;
The role of oxidized phospholipids, lipoprotein (a) and biomarkers of oxidized lipoproteins in chronically occluded coronary arteries in sudden cardiac death and following successful percutaneous revascularization
Keywords: فسفولیپید های اکسید شده; Chronic total occlusion; Oxidized phospholipids; Oxidized LDL; Angioplasty
Activation of stress signaling pathways by electrophilic oxidized and nitrated lipids
Keywords: فسفولیپید های اکسید شده; Fatty acid; Redox regulation; Nrf2; Keap1; Heat shock response; Unfolded protein response; Electrophilic stress response; HNE; Oxidized phospholipids; Nitroalkenes
Protein-oxidized phospholipid interactions in cellular signaling for cell death: From biophysics to clinical correlations
Keywords: فسفولیپید های اکسید شده; A2E; N-retinylidene-N-retinylethanolamine; 2DM; type 2 diabetes; apo; apolipoprotein; Aβ; Alzheimer β-peptide; AD; Alzheimer's disease; AMD; age-related macular degeneration; AMP; antimicrobial peptides; CMC; critical micelle concentration; cyt c; cytoc
Protein modification by aldehydophospholipids and its functional consequences
Keywords: فسفولیپید های اکسید شده; BSA; bovine serum albumin; BY; BODIPYâ¢; HAEC; human aortic endothelial cells; HDL; high density lipoprotein; HNE; hydroxyl-nonenal; HOdiA-PC; 1-palmitoyl-2-(5-hydroxy-8-oxo-6-octenedioyl) sn-glycero-3-phosphocholine; HOOA-PC; 1-palmitoyl-2-(5-hydroxy-8-
Oxidized Phospholipids Are Present on Plasminogen, Affect Fibrinolysis, and Increase Following Acute Myocardial Infarction
Keywords: فسفولیپید های اکسید شده; acute coronary syndromes; fibrinolysis; lipoprotein; lipoprotein(a); oxidized phospholipids; plasminogenACS, acute coronary syndrome(s); AMI, acute myocardial infarction; ANOVA, analysis of variance; apo(a), apolipoprotein (a); apoB, apolipoprotein B-100;
Uptake and protein targeting of fluorescent oxidized phospholipids in cultured RAW 264.7 macrophages
Keywords: فسفولیپید های اکسید شده; aSMase; acid sphingomyelinase; BSA; bovine serum albumin; BY; BODIPYâ¢; DMEM; Dulbecco's modified Eagle's medium; HAEC; human aortic endothelial cells; IL; interleukin; LDL; low density lipoprotein; MAPK; mitogen-activated protein kinase; mmLDL; minimall
Biophysics of lipid bilayers containing oxidatively modified phospholipids: Insights from fluorescence and EPR experiments and from MD simulations
Keywords: فسفولیپید های اکسید شده; Oxidized phospholipids; Liposome; Fluorescence; EPR; Molecular dynamics;
Inflammation-related gene expression by lipid oxidation-derived products in the progression of atherosclerosis
Keywords: فسفولیپید های اکسید شده; 7α-OH; 7α-hydroxycholesterol; 7-K; 7-ketocholesterol; 9-ONC; 9-oxononanoyl cholesterol; 15d-PGJ2; 15-deoxy-Î12,14-prostaglandin J2; α-EPOX; 5α,6α-epoxycholesterol; AP-1; activator protein-1; ARE; antioxidant-responsive element; ATF; activating trans
Catalytic reduction of carbonyl groups in oxidized PAPC by Kvβ2 (AKR6)
Keywords: فسفولیپید های اکسید شده; Kvβ; Catalysis; Oxidized phospholipids; Potassium channel; Mass spectrometry
Oxidized phospholipid-induced inflammation is mediated by Toll-like receptor 2
Keywords: فسفولیپید های اکسید شده; Oxidized phospholipids; Inflammation; Toll-like receptor; Macrophage; Free radicals;
The I4399M variant of apolipoprotein(a) is associated with increased oxidized phospholipids on apolipoprotein B-100 particles
Keywords: فسفولیپید های اکسید شده; Oxidized phospholipids; Lipoprotein(a); Genetics; Single nucleotide polymorphism; Coronary; Atherosclerosis
Membrane binding and anticoagulant properties of protein S natural variants
Keywords: فسفولیپید های اکسید شده; Thrombophilia; protein S deficiency; protein S domains; protein S activity; protein S-membrane binding; oxidized phospholipids
Activation of phospholipase A2 by 1-palmitoyl-2-(9'-oxo-nonanoyl)-sn-glycero-3-phosphocholine in vitro
Keywords: فسفولیپید های اکسید شده; Aβ; amyloid beta; C28-OPHPM; 1-octosanyl-2-(pyren-1-yl)hexanoyl-sn-glycero-3-phosphatidylmonomethyl ester; CMC; critical micelle concentration; CD; circular dichroism; DPPC; 1,2-dipalmitoyl-sn-glycero-3-phosphocholine; EDTA; ethylenediaminetetraacetic ac
A Lecinoxoid, an oxidized phospholipid small molecule, constrains CNS autoimmune disease
Keywords: فسفولیپید های اکسید شده; Oxidized phospholipids; Experimental autoimmune encephalomyelitis; T-cells
Experimental immunotherapeutic approaches for atherosclerosis
Keywords: فسفولیپید های اکسید شده; Atherosclerosis; Immunomodulation; Oxidized LDL; Oxidized phospholipids; Immunization; Tolerance; Antibodies; Adjuvants; Peptide
Oxidized phospholipids: Biomarker for cardiovascular diseases
Keywords: فسفولیپید های اکسید شده; Oxidized phospholipids; Atherosclerosis; Cardiovascular diseases; Inflammation
Plasma annexin A5 level relates inversely to the severity of coronary stenosis
Keywords: فسفولیپید های اکسید شده; Angiography; Annexin A5; Atherosclerosis; Cardiovascular diseases; Coronary disease; Coronary stenosis; Oxidized phospholipids; Oxidized low-density lipoprotein
Oxidized phospatidylcholine but not native phosphatidylcholine inhibits inducible nitric oxide synthase in RAW 264.7 macrophages
Keywords: فسفولیپید های اکسید شده; Oxidized phospholipids; Atherosclerosis; Inducible nitric oxide synthase; Murine macrophages
The oxidative modification hypothesis of atherosclerosis: The comparison of atherogenic effects on oxidized LDL and remnant lipoproteins in plasma
Keywords: فسفولیپید های اکسید شده; Oxidative modification; Oxidized LDL (Ox-LDL); Remnant lipoproteins; Remnant-like lipoprotein particle-cholesterol (RLP-C); Oxidized phospholipids; Endothelial dysfunction; Scavenger receptor; Lectin-like oxidized LDL receptor-1 (LOX-1); Endothelium-depen