دانلود مقالات ISI درباره P450 + ترجمه فارسی

Screening and prediction of reactive intermediates in a microreactor with immobilized rat hepatic microsomes using acetaminophen as a model drug

Keywords: Microsome; mGST; P450; Microreactor; Reactive intermediate; Biosensor; Immobilization

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

High abundance of testosterone and salivary androgen-binding protein in the lateral nasal gland of male mice

Keywords: Salivary androgen-binding protein; P450; Olfactory mucosa; Lateral nasal gland; Testosterone; Metabolism

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Development of immobilization technique for liver microsomes

Keywords: Microsome; P450; Phase I; Phase II; Microreactor;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Covalent immobilization of recombinant human cytochrome CYP2E1 and glucose-6-phosphate dehydrogenase in alumina membrane for drug screening applications

Keywords: P450; CYP2E1; Glucose-6-phosphate dehydrogenase; Immobilization; Reactor; Biosensor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Differences in CYP3A4 catalyzed bioactivation of 5-aminooxindole and 5-aminobenzsultam scaffolds in proline-rich tyrosine kinase 2 (PYK2) inhibitors: Retrospective analysis by CYP3A4 molecular docking, quantum chemical calculations and glutathione adduct

Keywords: P450; Reactive metabolite; Oxidation; Crystal structure; Glutathione; Orbitrap; Mass spectrometry

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Benzoxazinoid biosynthesis, a model for evolution of secondary metabolic pathways in plants

Keywords: Hydroxamic acids; Cytochrome P450 monooxygenase; DIBOA; DIMBOA; Evolution of secondary metabolism; Functional gene cluster; Glucosyltransferase; O-methyltransferase; 2-Oxoglutarate dependent dioxygenase; Tryptophan synthase; 2-ODD; 2-oxoglutarate dependen

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

A web-based resource for the Arabidopsis P450, cytochromes b5, NADPH-cytochrome P450 reductases, and family 1 glycosyltransferases (http://www.P450.kvl.dk)

Keywords: Bioinformatics; Web resource; P450; UGT; β-Glycosidases; CPR; Secondary metabolism; Evolution; Multi-gene family;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Alkoxyresorufin (methoxy-, ethoxy-, pentoxy- and benzyloxyresorufin) O-dealkylase activities by in vitro-expressed cytochrome P450 1A4 and 1A5 from common cormorant (Phalacrocorax carbo)

Keywords: AROD; Common cormorant; P450; CYP1A4; CYP1A5; Heterologous expression; Yeast

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

A phosphoproteomics approach to elucidate neuropeptide signal transduction controlling insect metamorphosis

Keywords: 20-hydroxyecdysone; PTTH; Phosphoproteomics; Spook; P450; Titanium dioxide; SIMAC

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Metabolism of carbosulfan. I. Species differences in the in vitro biotransformation by mammalian hepatic microsomes including human

Keywords: Pesticides; Toxicokinetics; P450; In vitro; Metabolism; Risk assessment

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

New cytochrome P450 1B1, 1C2 and 1D1 genes in the killifish Fundulus heteroclitus: Basal expression and response of five killifish CYP1s to the AHR agonist PCB126

Keywords: P450; CYP1; Fundulus heteroclitus; Fish; PCB; AHR agonist; Pollution;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Three conazoles increase hepatic microsomal retinoic acid metabolism and decrease mouse hepatic retinoic acid levels in vivo

Keywords: atRA, all trans retinoic acid; P450, cytochrome P450Conazoles; All trans retinoic acid; P450; Triadimefon; Propiconazole; Myclobutanil

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

N-(3,4-dimethoxyphenethyl)-4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2[1H]-yl)-6,7-dimethoxyquinazolin-2-amine (CP-100,356) as a “chemical knock-out equivalent” to assess the impact of efflux transporters on oral drug absorption in the rat

Keywords: MDR1; BCRP; CP-100,356; drug absorption; bioavailability; P450; efflux; drug-drug interaction;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Cooperative properties of cytochromes P450

Keywords: P450; Allosteric effects; Cooperativity; Drug-drug interactions; 1-PB; 1-pyrene butanole; 7-BQ; 7-benzyloxyquinoline; 9-AP; 9-aminophenantrene; ANF; α-naphthoflavone; BI; binding isotherm; FRET; Förster resonance energy transfer; ITC; isothermal titra

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2009 سفارش ترجمه

The ferrous-oxy complex of human aromatase

Keywords: Human aromatase; P450; CYP19; Catalytic intermediates; Oxy-ferrous complex; Nanodisc

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Pyridine as novel substrate for regioselective oxygenation with aromatic peroxygenase from Agrocybe aegerita

Keywords: AaP, Agrocybe aegerita peroxygenase; CPO, chloroperoxidase; P450, cytochrome P450 dependent enzyme; MMO, methane monooxygenase; PY, pyridineHaloperoxidase; Oxygenation; P450; Pyridine; Pyridine N-oxide; Agrocybe

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Molecular cloning of Bombyx mori cytochrome P450 gene and its involvement in fluoride resistance

Keywords: Bombyx mori; Fluoride; P450; FDD-PCR; Quantitative real-time PCR (Q-PCR);

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Bioconversion by functional P450 1A9 and P450 1C1 of Anguilla japonica

Keywords: Fish; Flavanone; HPLC; Monooxygenase; P450; Steroids

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Toluene-induced hearing loss in phenobarbital treated rats

Keywords: AcOH; acetic acid; ANOVA; analysis of variance; BMA; benzyl mercapturic acid; CTRL; control; DMSO; dimethylsulfoxide; HA; hippuric acid; HPLC; high performance liquid chromatography; IC; inferior colliculus; IHC; inner hair cell; LOD; limit of detection;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Bioactivation of the tricyclic antidepressant amitriptyline and its metabolite nortriptyline to arene oxide intermediates in human liver microsomes and recombinant P450s

Keywords: P450, cytochrome P450; TCAs, tricyclic antidepressants; PI, precursor ion; EPI, enhanced product ion; HLM, human liver microsomes; GSH, glutathioneAmitriptyline; Nortriptyline; Bioactivation; P450; Hepatotoxicity; Arene oxide

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

New players in the regulation of ecdysone biosynthesis

Keywords: ecdysone; cholesterol; PTTH; P450

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Genomic analysis of detoxification genes in the mosquito Aedes aegypti

Keywords: Aedes aegypti; P450; Glutathione transferases; Carboxylesterases; Detox chip; MicroarrayCCE, carboxy/cholinesterases; P450, cytochrome P450 monooxygenases; GST, glutathione transferases

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Relative contribution of rat cytochrome P450 isoforms to the metabolism of caffeine: The pathway and concentration dependence

Keywords: CYP; P450; cytochrome P450; FMO; flavin-containing monooxygenase; HPLC; high performance liquid chromatography; αNF; α-naphthoflavone; SULF; sulfaphenazole; CIM; cimetidine; QUIN; quinine; trans-DCE; trans-1,2-dichloroethylene; ERY; erythromycin; Km; th

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Structure–activity relationship of uniconazole, a potent inhibitor of ABA 8′-hydroxylase, with a focus on hydrophilic functional groups and conformation

Keywords: Uniconazole; Abscisic acid; ABA; P450; Azole

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

A combination of 3D-QSAR, docking, local-binding energy (LBE) and GRID study of the species differences in the carcinogenicity of benzene derivatives chemicals

Keywords: Carcinogenicity; 3D-QSAR; Docking; GRID; LBE; P450

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Sugar-mediated lyoprotection of purified human CYP3A4 and CYP2D6

Keywords: Biocatalyst; Cryoprotection; Freeze-drying; Lyophilization; P450; Saccharide

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Identification of covalent modifications in P450 2E1 by 1,2-epoxy-3-butene in vitro

Keywords: Butadiene; P450; Carcinogen metabolism

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Enzymes and pharmacogenetics of cardiovascular drugs

Keywords: Pharmacogenetics; Pharmacogenomics; Pharmacokinetics; Pharmacodynamics; Cardiovascular drugs; Cytochrome; P450

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

A comparison of substrate dynamics in human CYP2E1 and CYP2A6

Keywords: CYP2E1; CYP2A6; Isotope effect; Cooperativity; Allosterism; Dynamics; P450; kH/kD; Xylene

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Hydroxylation and epoxidation reactions catalyzed by CYP153 enzymes

Keywords: P450; Epoxidation; Hydroxylation; CYP153; Biotransformation; Functional expression

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Evaluation of cytochrome P450BSβ reactivity against polycyclic aromatic hydrocarbons and drugs

Keywords: CYPBSβ; Drugs; PAH; P450

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

SnO2–poly(diallyldimethylammonium chloride) films: Electrochemical evidence for heme protein absorption, denaturation, and demetallation

Keywords: Hemoglobin; Cytochrome; P450; Protein; Iron; SnO2; Nanoparticle; Thin film; Denaturation; Demetallation; Catalysis; Voltammetry; Sensor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Steviol glycoside biosynthesis

Keywords: Stevia rebaudiana; Asteraceae; Stevia; Biosynthesis; Diterpene glycoside; Terpene cyclase; P450; Glucosyltransferase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Electrophysiological responses to affective stimuli in Mexican Americans: Relationship to alcohol dependence and personality traits

Keywords: Mexican Americans; Alcohol dependence; ASPD; Emotion; P450; Affective stimuli; Anxiety; Affective; Extraversion; Neuroticism;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Escherichia coli as a platform for functional expression of plant P450 carotene hydroxylases

Keywords: Carotene; P450; CYP97; Hydroxylases; Vitamin A; Oryza sativa; Metabolic engineering; Xanthophylls; Plants; Escherichia coli functional complementation

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Asymmetrical ligand binding by abscisic acid 8′-hydroxylase

Keywords: ABA; Abscisic acid; P450

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

The role of the heme propionates in heme biochemistry

Keywords: APX; QM/MM; P450; Propionates; Cytochrome; CYP101; Compound I

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

The hepatic cytochrome P450 reductase null mouse as a tool to identify a successful candidate entity

Keywords: Transgenic; P450; Reductase; Toxicokinetics; Pharmacokinetics

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Cloning of chicken lanosterol 14α-demethylase (CYP51) cDNA: Discovery of a testis-specific CYP51 transcript

Keywords: Lanosterol 14α-demethylase; CYP51; P450; Alternative splicing; Testis-specific exon 1; Chicken; Maturation; Species difference

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Characterization of CYP1A enzyme in Adélie penguin liver

Keywords: Adélie penguin; Antarctica; CYP1A; P450; Drug metabolism; Liver microsomes; Environment; Pygoscelis adeliae

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Hippocampal synthesis of estrogens and androgens which are paracrine modulators of synaptic plasticity: Synaptocrinology

Keywords: neurosteroid; P450; hippocampus; estradiol; endocrine disrupter; BPA; bisphenol A; DES; diethylstilbestrol; DHEA; dehydroepiandrosterone; LTP; long-term potentiation; PBR; peripheral benzodiazepine receptor; PREG; pregnenolone; RNase; ribonuclease; StAR;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Intermoult duration affects the susceptibility of shore crabs Carcinus maenas (L.) to pyrene and their ability to metabolise it

Keywords: P450; CYP; Monooxygenases; Polycyclic aromatic hydrocarbons; Phase I metabolism; Pyrene; 1-Hydroxypyrene; Crustacean

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Metabolism of coumarin by human P450s: A molecular modelling study

Keywords: CYP, cytochrome P450 when referring to a specific enzyme or family/subfamily; P450, enzymes in either a general or non-specific manner; SRS, substrate recognition site(s)Coumarin; Metabolism; Molecular modelling; P450

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Effect of l-carnitine supplementation on xenobiotic-metabolizing hepatic enzymes exposed to methanol

Keywords: l-carnitine; Methanol; P450; Liver; Rat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Fluconazole-induced hepatic cytochrome P450 gene expression and enzymatic activities in rats and mice

Keywords: Fluconazole; PCR; P450; Cyp; Alkoxyresorufin O-dealkylation; Western

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Uncovering the complex metabolic network underlying diterpenoid phytoalexin biosynthesis in rice and other cereal crop plants

Keywords: CPP; copalyl diphosphate; CPS; copalyl diphosphate synthase; CPSL; copalyl diphosphate synthase-like; P450; cytochrome P450; GGPP; geranylgeranyl diphosphate; KO; kaurene oxidase; KOL; kaurene oxidase-like; KS; kaurene synthase; KSL; kaurene synthase-like

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Functional expression of a bark beetle cytochrome P450 that hydroxylates myrcene to ipsdienol

Keywords: P450; Bark beetle; Pheromone biosynthesis; Detoxification; Functional expression; Monoterpene; Baculovirus;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Gender-specific induction of cytochrome P450s in nonylphenol-treated FVB/NJ mice

Keywords: Nonylphenol; P450; Gender-specific; PXR; CAR; Sexual dimorphism

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

The status of high-valent metal oxo complexes in the P450 cytochromes

Keywords: P450; Compound I; Ferryl; Metal-Oxo; X-ray

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Cytochrome P450 expression and metabolic activation of cooked food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in MCF10A breast epithelial cells

Keywords: PhIP; Heterocyclic amines; Cooked food mutagens; DNA adducts; Human breast epithelial cells; CYP; P450; Breast carcinogenesisAh receptor, aryl hydrocarbon receptor; EROD, ethoxyresorufin O-deethylase; PhIP, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه