دانلود مقالات ISI درباره P70S6K + ترجمه فارسی

ATP-mediated protein kinase B Akt/mammalian target of rapamycin mTOR/p70 ribosomal S6 protein p70S6 kinase signaling pathway activation promotes improvement of locomotor function after spinal cord injury in rats

Keywords: mTOR; rapamycin; signal transduction pathway; locomotor functional recovery; spine; nervous system injury; Akt; protein kinase B; BBB; Basso-Beattie-Bresnahan; BSA; bovine serum albumin; CNS; central nervous system; DAB; 3,3-diaminobenzidine; GAPDH; g

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2010 سفارش ترجمه

4-(Benzimidazol-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: Potent and selective p70S6 kinase inhibitors

Keywords: p70S6K; p70S6 Kinase; 1,2,5-Oxadiazole; 3-Aminofurazan

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

d-Glucosamine down-regulates HIF-1α through inhibition of protein translation in DU145 prostate cancer cells

Keywords: d-Glucosamine; Hif-1α; VEGF; p70S6K; Prostate cancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

TIS21/BTG2/PC3 and cyclin D1 are key determinants of nuclear diacylglycerol kinase-ζ-dependent cell cycle arrest

Keywords: cdk; cyclin dependent kinase; DG; diacylglycerol; DGK; diacylglycerol kinase; ECL; enhanced chemiluminescence; GSK; glycogen synthase kinase; mTOR; mammalian Target Of Rapamycin; NLS; nuclear localization signal; p70S6K; p70S6 kinase; PA; phosphatidic aci

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

AMPKα2 counteracts the development of cardiac hypertrophy induced by isoproterenol

Keywords: AMPK, AMP-activate protein kinase; LV, left ventricle; mTOR, mammalian target of rapamycin; p70S6K, p70 ribosomal S6 protein kinase; PKB, protein kinase BAMPK; Cardiac hypertrophy; p70S6K; Heart; Isoproterenol

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

In vitro metformin anti-neoplastic activity in epithelial ovarian cancer

Keywords: Metformin; Ovarian cancer; AMPK; p70S6K; S6K; OVCAR; Cisplatin; Translational research

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Effects of postnatal ethanol exposure at different developmental phases on neurotrophic factors and phosphorylated proteins on signal transductions in rat brain

Keywords: Ethanol; GDNF; Akt; Developmental neurotoxicity; MAPK; p70S6K

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

Keywords: HCC; Hepatocellular carcinoma; VEGF; vascular endothelial growth factor; BEV; Bevacizumab; mTOR; mammalian target-of-rapamycin; p70S6K; p70S6 kinase; RPS6; ribosomal S6 protein; 4EBP1; eukaryotic initiation factor 4E-binding protein 1; RAPA; rapamycin; IP

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

PGF2α-associated vascular smooth muscle hypertrophy is ROS dependent and involves the activation of mTOR, p70S6k, and PTEN

Keywords: A7r5; VSMC; PGF2α; Hypertrophy; p70S6k; PTEN;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

ABT-869, a multi-targeted tyrosine kinase inhibitor, in combination with rapamycin is effective for subcutaneous hepatocellular carcinoma xenograft

Keywords: HCC; hepatocellular carcinoma; RTKIs; tyrosine kinase inhibitors; MAPK; mitogen activated protein kinase; VEGF; vascular endothelial growth factor; mTOR; mammalian target of rapamycin; p70S6K; p70S6 kinase; 4EBP1; eukaryotic initiation factor 4E-binding p

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Chronic alcohol consumption alters mammalian target of rapamycin (mTOR), reduces ribosomal p70s6 kinase and p4E-BP1 levels in mouse cerebral cortex

Keywords: Alcohol; Cerebral cortex; Akt; mTOR; p70s6k; 4E-BP1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

d-Glucosamine inhibits proliferation of human cancer cells through inhibition of p70S6K

Keywords: d-Glucosamine; p70S6K; RPS6; Cell proliferation; Prostate cancer; Breast cancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Reversine stimulates adipocyte differentiation and downregulates Akt and p70s6k signaling pathways in 3T3-L1 cells

Keywords: Reversine; Adipocyte differentiation; Akt; p70s6k

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Phosphorylation events implicating p38 and PI3K mediate tungstate-effects in MIN6 beta cells

Keywords: PDX-1; pancreatic duodenal homeobox-1; p38; p38 MAP kinase; PI3K; phosphatidylinositol 3-kinase; p70S6K; p70S6 kinase; nSTZ; neonatally streptozotocin; GIIS; glucose-induced insulin secretion; Tungstate; Beta cell; Insulin secretion; Pancreatic duodenal h

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Effects of rapamycin on cell proliferation and phosphorylation of mTOR and p70S6K in HepG2 and HepG2 cells overexpressing constitutively active Akt/PKB

Keywords: Human liver carcinoma cells; Constitutively active Akt/PKB; mTOR; p70S6k; Rapamycin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Acetaldehyde promotes rapamycin-dependent activation of p70S6K and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells

Keywords: Acetaldehyde; Glucose uptake; IRS-2; Akt; mTOR; p70S6K; 4E-BP1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

EGF AND TGF-α motogenic activities are mediated by the EGF receptor via distinct matrix-dependent mechanisms

Keywords: EGF; TGF-α; Extracellular matrix; Signal transduction; Cell motility; Hyaluronan; Vitronectin; CD44; αvβ3; p70S6K; Phospholipase Cγ

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells

Keywords: ATL, adult T-cell leukemia; HTLV-1, human T-cell lymphotropic virus type I; PI3-K, phosphatidylinositol 3-kinase; mTOR, mammalian target of rapamycin; p70S6K, p70 S6 kinase; 4E-BP-1, eukaryotic initiation factor 4E-binding protein-1PI3K; Akt; mTOR; p70S6K

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Activation of the mTOR pathway in sporadic angiomyolipomas and other perivascular epithelioid cell neoplasms

Keywords: AML; PEComa; Immunohistochemistry; Tuberous sclerosis; TSC2; p70S6K

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Activation of adenosine monophosphate activated protein kinase inhibits growth of multiple myeloma cells

Keywords: Multiple myeloma; Cell growth; AMPK; ERK; P70S6K; Proliferation

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

An activated mTOR/p70S6K signaling pathway in esophageal squamous cell carcinoma cell lines and inhibition of the pathway by rapamycin and siRNA against mTOR

Keywords: mTOR; p70S6K; Rapamycin; siRNA; Apoptosis; Esophageal squamous cell carcinoma

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Glutamate-dependent translational regulation in cultured Bergmann glia cells: Involvement of p70S6K

Keywords: p70S6K; glutamate receptors; Bergmann glia; mTOR; translational control; Akt I; 1L-6-hydroxymethyl-chiro-inositol 2-(R)-2-O-methyl-3-O-octadecylcarbonate; AMPA; amino α-3-hydroxy-5-methyl-4-isoaxazolepropionate; ANOVA; analysis of variance; BAPTA-AM; 1,2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Stress-induced activation of the AMP-activated protein kinase in the freeze-tolerant frog Rana sylvatica

Keywords: Metabolic rate depression; AMPK; Energy stress; mTOR; eEF2; eEF2K; p70S6K; 4E-BP1; Ribosomal protein S6

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

The rapamycin analog CCI-779 is a potent inhibitor of pancreatic cancer cell proliferation

Keywords: CCI-779; Rapamycin; Pancreatic cancer; p70s6k; Akt; PI 3-kinase; c-Jun; Drug resistance;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Compensatory recovery of liver mass by Akt-mediated hepatocellular hypertrophy in liver-specific STAT3-deficient mice

Keywords: Hepatectomy; Cell size; Cell proliferation; Liver regeneration; mTOR; GSK-3; p70S6K;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Adrenaline potentiates insulin-stimulated PKB activation via cAMP and Epac: implications for cross talk between insulin and adrenaline

Keywords: PI 3-kinase; PKA; 8-pCPT-2′-O-Me-cAMP; p70S6K; Akt;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Evaluation of the role of AMP-activated protein kinase and its downstream targets in mammalian hibernation

Keywords: ACC; acetyl-CoA carboxylase (EC 6.4.1.2); AMPK; AMP-activated protein kinase; B; brain; BAT; brown adipose tissue; GS; glycogen synthase (EC 2.4.1.11); eEF2; eukaryotic elongation factor-2; eEF2K; eukaryotic elongation factor-2 kinase; HSL; hormone-sensit

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Aging alters vascular mechanotransduction: Pressure-induced regulation of p70S6k in the rat aorta

Keywords: Aorta; p70S6k; GSK-3β; PTEN; SHP-2; Mechanotransduction; Aging;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Isorhapontigenin, a new resveratrol analog, attenuates cardiac hypertrophy via blocking signaling transduction pathways

Keywords: ISO; isorhapontigenin; Ang II; angiotensin II; PDTC; pyrrolidine dithiocarbamate; NAC; N-acetylcysteine; DCFH-DA; 2′,7′-dichlorofluorescein diacetate; PMA; phorbol 12-myristate 13-acetate; ROS; reactive oxygen species; TAC; transaortic constriction; M

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه