Keywords: Carcinogenesis; Chemoprevention; Chemotherapy; Oxidative stress; Nrf2; Phytochemicals; AKT; protein kinase B; AMPK; AMP-activated protein kinase; ARE; antioxidant response element; ATF-2; activating transcriptional factor; BBN; N-butyl-N-(4-hydroxybutyl)n
مقالات ISI (ترجمه نشده)
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Keywords: BNE; blue native electrophoresis; CAT; catalase; CCCP; carbonyl cyanide 3-chlorophenylhydrazone; DCF; 2',7'-dichlorofluorescin diacetate; DHE; dihydroethidium; DHR123; dihydrorhodamine 123; ETC; electron transport chain; FCCP; carbonyl cyanide p-(trif
Keywords: Epigenetics; Phytochemicals; DNA-methylation; Histone-modification; miRNA; Carcinogenesis; Akt; v-akt murine thymoma viral oncogene homolog 1; AP-1; Activator Protein-1; Bax; BCL2-associated X protein; Bcl2; B-cell CLL/lymphoma 2; Bcl-xL; B-cell lymphoma-
4-Methylthio-3-butenyl isothiocyanate mediates nuclear factor (erythroid-derived 2)-like 2 activation by regulating reactive oxygen species production in human esophageal epithelial cells
Keywords: Chemoprevention; Isothiocyanate; 4-Methylthio-3-butenyl isothiocyanate; Nuclear factor (erythroid-derived 2)-like 2; Reactive oxygen species; AITC; allyl isothocyanate; AP-1; activator protein-1; BITC; butyl isothiocyanate; ERK; extracellular signal-regul
A 14-day repeated-dose oral toxicological evaluation of an isothiocyanate-enriched hydro-alcoholic extract from Moringa oleifera Lam. seeds in rats
Keywords: ANOVA; analysis of variance; GLP; good laboratory practice; ITC; isothiocyanate; MIC-1; moringa isothiocyanate-1; MICs; moringa isothiocyanates; MSE; moringa seed extract; NF-κB; nuclear factor kappa B; NO; nitric oxide; NOAEL; no observed adverse effect
Microcystin induction small Maf protein involve in transcriptional regulation of GST from freshwater mussel Cristaria plicata
Keywords: Maf; musculoaponeurotic fibrosarcoma; GST; glutathione S-transferase; ARE; antioxidant response element; EpRE; electrophile response element; CNC; cap “n” collar; bZIP; basic region leucine zipper; Nrf2; nuclear factor erythroid-2p45-related factor 2;
Phenethyl isothiocyanate suppresses cancer stem cell properties in vitro and in a xenograft model
Keywords: Cancer stem cells; PEITC; EpCAM; Oct4; Xenograft model; bFGF; basic fibroblast growth factor; EpICD; intracellular domain of EpCAM; FHL2; four and one-half LIM domains protein 2; GSK-3β; glycogen synthase kinase-3 beta; Lef1; lymphoid enhancer-binding fa
The glutathione transferase family of Chlamydomonas reinhardtii: Identification and characterization of novel sigma class-like enzymes
Keywords: AITC; Allyl isothiocyanate; BDNB; 1-Bromo-2,4-dinitrobenzene; CDNB; 1-chloro-2,4-dinitrobenzene; CuOOH; cumene hydroperoxide; DHAR; dehydroascorbate reductase; dNTPs; deoxyribonucleotide triphosphates; DTT; p,pâ²-dichloro-diphenyl-trichloroethane; EA; Et
Epigenetic reactivation of RASSF1A by phenethyl isothiocyanate (PEITC) and promotion of apoptosis in LNCaP cells
Keywords: PEITC; phenethyl isothiocyanate; RASSF1A; RAS superfamily protein isoform 1A; DNMT; DNA methyl transferases; HDAC; histone deacetylases; MSP; methylation specific PCR; BGS; bisulfite genomic sequencing; PCa; prostate cancer; RASSF1A; Epigenetics; Demethyl
Substrate specificities of two tau class glutathione transferases inducible by 2,4,6-trinitrotoluene in poplar
Keywords: Allyl-ITC; allyl isothiocyanate; Benzyl-ITC; benzyl isothiocyanate, CDNB, 1-chloro-2,4-dinitrobenzene; CuOOH; cumene hydroperoxide; DHA; dehydroascorbate; DNT; 2,4-dinitrotoluene; GST; glutathione transferase; NBD-Cl; 7-chloro-4-nitrobenzo-2-oxa-1,3-diazo
Inhibition of crosstalk between Bcr-Abl and PKC signaling by PEITC, augments imatinib sensitivity in chronic myelogenous leukemia cells
Keywords: p210bcr/abl; PKC; Raf1; ERK1/2; PEITC; Leukemia
Evolution of the active site of human glutathione transferase A2-2 for enhanced activity with dietary isothiocyanates
Keywords: GST; glutathione transferase; GSH; glutathione; AITC; allyl isothiocyanate; BITC; benzyl isothiocyanate; EA; ethacrynic acid; PEITC; phenethyl isothiocyanate; PITC; propyl isothiocyanate; CDNB; 1-chloro-2,4-dinitrobenzene; Non; nonenal; BN; butylnitrite;
PEITC induces apoptosis of Human Brain Glioblastoma GBM8401 Cells through the extrinsic- and intrinsic -signaling pathways
Keywords: PEITC; Apoptosis; Caspases; Mitochondria; Glioblastoma;
BAG3 down-modulation sensitizes HPV18+ HeLa cells to PEITC-induced apoptosis and restores p53
Keywords: BAG3; HeLa cells; HPV18; E6; p53; PEITC
Phenethyl isothiocyanate: A comprehensive review of anti-cancer mechanisms
Keywords: BaP; Benzo(a)pyrene; BCRP; Breast Cancer Resistance Protein; CSC; Cancer Stem cells; ECS; Environmental Cigarette Smoke; GPX; Glutathione peroxidase; GSH; Glutathione; GST; Glutathione S-transferase; HBEC; Human Bronchial Epithelial Cells; HBP; 4-hydroxy-
PARP and other prospective targets for poisoning cancer cell metabolism
Keywords: ATP; adenosine 5â²-triphosphate; 3-BrPA; 3-bromopyruvate; EGFR; epidermal growth factor receptor; FDA; food and drug administration; GSH; glutathione; GSSG; oxidized GSH; GST; glutathione S-transferase; HDAC; histone deacetylase; HIF1; hypoxia inducible
Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1α and VEGF expression in human glioma cells
Keywords: PEITC; phenethyl isothiocyanate; PAGE; polyacrylamide gel electrophoresis; PBS; phosphate-buffered saline; SDS; sodium dodecyl sulphate; HIF-1α; hypoxia-inducible factor-1; VEGF; vascular endothelial growth factor; uPA; urokinase-type plasminogen activat
Aberrant activation of M phase proteins by cell proliferation-evoking carcinogens after 28-day administration in rats
Keywords: Carcinogen; M phase; Cell proliferation; Immunohistochemical analysis; SDM; sulfadimethoxine; PEITC; phenylethyl isothiocyanate; BHA; butylated hydroxyanisole; CC; catechol; PhIP; 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine; CDCA; chenodeoxycholic aci
β-Phenylethyl isothiocyanate reverses platinum resistance by a GSH-dependent mechanism in cancer cells with epithelial-mesenchymal transition phenotype
Keywords: Chemo-resistance; PEITC; Glutathione; EMT; Chemotherapy
The influence of durian (Durio zibethinus Murray cv. Monthong) on conditioned taste aversion to ethanol
Keywords: ADH; alcohol dehydrogenase; ALDH; aldehyde dehydrogenase; DER; disulfiram-ethanol reaction; CTA; conditioned taste aversion; PEITC; phenethyl isothiocyanate; Acetaldehyde; Aldehyde dehydrogenase (ALDH); Cabbage; Disulfiram-ethanol reaction (DER); Durian;
Phenylalkyl isoselenocyanates vs phenylalkyl isothiocyanates: Thiol reactivity and its implications
Keywords: ITCs; isothiocyanates; ISCs; isoselenocyanates; BITC; benzyl isothiocyanate; PEITC; phenethylisothiocyanate; PBITC; phenylbutylisothiocyanate; PHITC; phenylhexylisothiocyanate; ISC-1; benzyl isoselenocyanate; ISC-2; phenethylisoselenocyanate; ISC-4; pheny
Glutathione and modulation of cell apoptosis
Keywords: âΨ; mitochondrial membrane potential; ANT; adenine nucleotide translocase; Apaf-1; apoptotic protease-activating factor-1; ASK-1; apoptosis signal-regulating kinase-1; ATO; arsenic trioxide; AVD; apoptotic volume decrease; BSO; l-buthionine (S,R)-sulfo
NF-κB Essential Modifier Is Required for Hepatocyte Proliferation and the Oval Cell Reaction After Partial Hepatectomy in Mice
Keywords: PEITC; Liver Disease; Mouse Model; Tissue Regeneration; BHA; butylated hydroxyanisole; BrdU; 5-bromo-2â²-deoxyuridine; DAPI; 4â²,6-diamidino-2-phenylindole; DDC; 3,5-diethoxycarbonyl-1,4-dihydro-collidin; DSB; double-strand break; FHC; ferritin heavy ch
Allyl-, butyl- and phenylethyl-isothiocyanate activate Nrf2 in cultured fibroblasts
Keywords: AITC; allyl isothiocyanate; ARE; antioxidant response element; BITC; butyl isothiocyanate; CpG; cytosine-phospho-guanine; ERK; extracellular signal-regulated kinase; FCS; fetal calf serum; γGCS; γ-glutamyl cysteine synthetase; HO-1; heme oxygenase-1; IT
Targeting autophagy during cancer therapy to improve clinical outcomes
Keywords: AMPK; AMP activated protein kinase; ATG; autophagy-related genes; Bif-1; endophilin B1; BNIP3; Bcl-2/adenovirus E1B 19Â kDa-interacting protein; CML; chronic myeloid leukemia; CQ; chloroquine; DAP1; death-associated protein 1; HCQ; hydroxychloroquine; HDA
Metabolism of isothiocyanates in individuals with positive and null GSTT1 and M1 genotypes after drinking watercress juice
Keywords: Isothiocyanates; Watercress; PEITC; GST genotype; Cancer prevention;
Mitochondrial respiratory chain involvement in peroxiredoxin 3 oxidation by phenethyl isothiocyanate and auranofin
Keywords: AFN; auranofin; NEM; N-ethylmaleimide; PEITC; phenethyl isothiocyanate; Prx; peroxiredoxin; Ï0; mitochondrial DNA deplete; TrxR; thioredoxin reductase; Hydrogen peroxide; Redox signaling; Oxidative stress; Thioredoxin reductase; Thioredoxin; Mitochondria
Modulation of genomic and postgenomic alterations in noncancer diseases and critical periods of life
Keywords: AP-1; activator protein-1; BAL; bronchoalveolar lavage; 5,6-BF; 5,6-benzoflavone; B(a)P; benzo(a)pyrene; COPD; chronic obstructive pulmonary diseases; CS; cigarette smoke; Cx43; connexin 43; DMBA; 7,12-dimethylbenz(a)anthracene; ÉdA; 1,N-ethenodeoxyadeni
Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from Brassicaceae
Keywords: GNS; gluconasturtiin; GRA; glucoraphanin; IC50; half-maximal inhibitory concentration; Myr; myrosinase; PARP; poly(ADP-ribose)polymerase; PEITC; β-phenethyl isothiocyanate; Isothiocyanates; Indoles; Apoptosis; Caspases; Colon cancer; Bcl-2 family protein
Comparison of phenethyl and 6-phenylhexyl isothiocyanate-induced toxicity in rat esophageal cell lines with and without glutathione depletion
Keywords: BSO; buthionine sulfoximine; CHX; 2-cyclohexene-1-one; DDT; dichlorodiphenyltrichloroethane; GSH; glutathione; ITCs; isothiocyanates; MTT; [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide]; NMBA; N-nitrosomethylbenzylamine; NNK; 4-(methylnit
β-Phenylethyl isothiocyanate mediated apoptosis; contribution of Bax and the mitochondrial death pathway
Keywords: PEITC; β-phenylethyl isothiocyanate; GSH; glutathione; MMP; mitochondrial membrane potential; CsA; cyclosporine A; Tfz; trifluoperazine; BA; Bongkrekic acid; MPT; mitochondrial permeability transition pore; mBCl; monochlorobimane; Rh-123; rhodamine-123;
Induction of apoptosis in tumor cells by naturally occurring sulfur-containing compounds
Keywords: AITC; allyl-isothiocyanate; ARE; antioxidant response element; BITC; benzyl-isothiocyanate; DADS; diallyl disulfide; DAS; diallyl sulfide; DATS; diallyl trisulfide; HSPs; heat shock proteins; JNK; c-Jun N-terminal kinases; MAPKs; the mitogen-activated pro