دانلود مقالات ISI درباره فسفینوزیتید 3-کیناز + ترجمه فارسی

Modulating autophagy in cancer therapy: Advancements and challenges for cancer cell death sensitization

Keywords: فسفینوزیتید 3-کیناز; 3-MA; 3-Methyl Adenine; Akt; Protein kinase B; AMP; Adenosine monophosphate; AMPK; AMP-activated protein kinase; Atg; Autophagy related genes; ATP; Adenosine triphosphate; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-associated X protein; BCL-2; B-

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

Aberrant regulation of the Akt signaling network by human cytomegalovirus allows for targeting of infected monocytes

Keywords: فسفینوزیتید 3-کیناز; Cytomegalovirus; Monocytes; Small-molecule inhibitor; HCMV; human cytomegalovirus; h; hour; EGF; epidermal growth factor; EGFR; EGF receptor; αvβ3; alpha v beta 3 integrin; gB; glycoprotein B; gH; glycoprotein H; PI3K; phosphoinositide 3-kinase; PTEN; p

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

Ferulic acid-loaded nanostructured lipid carriers: A promising nanoformulation against the ischemic neural injuries

Keywords: فسفینوزیتید 3-کیناز; Ferulic acid; Nanostructured lipid carriers; Ischemic stroke; Phosphoinositide 3-kinase;

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2018 سفارش ترجمه

ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway

Keywords: فسفینوزیتید 3-کیناز; Akt; oncogene in the transforming retrovirus, AKT8; AP-1; activator protein 1; ARAF; v-raf murine sarcoma 3611 viral oncogene homologue; ASK1; apoptosis signal-regulating kinase 1; BCL2; B-cell lymphoma 2; BCL-XL; B-cell lymphoma extra large; BRAF; v-raf

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2018 سفارش ترجمه

The role of TAM family receptors and ligands in the nervous system: From development to pathobiology

Keywords: فسفینوزیتید 3-کیناز; ACSF; artificial cerebral spinal fluid; APP; amyloid precursor protein; BBB; blood-brain-barrier; BCECs; brain capillary endothelial cells; C57Bl6/J; strain of mice for MOG-induce EAE and cuprizone studies; CNS; central nervous system; DKO; Gas6−/−Axl

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy as a pharmacological target in hematopoiesis and hematological disorders

Keywords: فسفینوزیتید 3-کیناز; 3-MA; 3-methyladenine; ALL; acute lymphoblastic leukemia; AMKL; acute megakaryoblastic leukemia; AML; acute myeloid leukemia; AMPK; 5′-adenosine monophosphate-activated protein kinase; APL; acute promyelocytic leukemia; Atg; autophagy-related proteins;

دانلود رایگان متن کامل مقاله ISI 80 صفحه سال انتشار : 2018 سفارش ترجمه

Chronopathophysiological implications of orexin in sleep disturbances and lifestyle-related disorders

Keywords: فسفینوزیتید 3-کیناز; Aβ; amyloid β; AI; androgeno-independent; BAT; brown adipose tissue; BNST; bed nucleus of the stria terminalis; CeA; central nucleus of amygdala; CSF; cerebrospinal fluid; DMNV; dorsal motor nucleus of the vagus; DORA; dual orexin receptor antagonist; D

دانلود رایگان متن کامل مقاله ISI 95 صفحه سال انتشار : 2018 سفارش ترجمه

Flavan 3-ol delays the progression of disuse atrophy induced by hindlimb suspension in mice

Keywords: فسفینوزیتید 3-کیناز; EDL; Extensor digitorum longus; FL; Flavan 3-ol; GC; Gastrocnemius; MuRF1; Muscle ring finger-1; p70S6K; p70S6 kinase; PGC-1α; Proliferator-activated receptor gamma coactivator-1 alpha; PI3K; Phosphoinositide 3-kinase; SOL; Soleus; TA; Tibialis anterior;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

MEK and PI3K catalytic activity as predictor of the response to molecularly targeted agents in triple-negative breast cancer

Keywords: فسفینوزیتید 3-کیناز; Catalytic activity; MEK; PI3K; Drug sensitivity; Triple-negative breast cancer; MAPK; mitogen-activated protein kinase; MEK; mitogen-activated protein kinase kinase; PI3K; phosphoinositide 3-kinase; TNBC; triple-negative breast cancer;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Synergistic effects of 15-deoxy Δ12,14-prostaglandin J2 on the anti-tumor activity of doxorubicin in renal cell carcinoma

Keywords: فسفینوزیتید 3-کیناز; Renal cell carcinoma; 15-deoxy Δ12,14-prostaglandin J2; Doxorubicin; Phosphoinositide 3-kinase; Chemoresistant;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Beclin1 antagonizes LAPTM4B-mediated EGFR overactivation in gastric cancer cells

Keywords: فسفینوزیتید 3-کیناز; LAPTM4B; lysosome-associated transmembrane protein 4β; EGFR; epidermal growth factor receptor; TAP; tandem affinity purification; TKI; tyrosine kinase inhibitor; HER; human epidermal growth factor receptor; BSA; bovine serum albumin; MCS; multiple clonin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Too much of a good thing: How modulating LTB4 actions restore host defense in homeostasis or disease

Keywords: فسفینوزیتید 3-کیناز; LT; leukotriene; PAMP; pathogen associated molecular patterns; PRR; pattern recognition receptor; AA; arachidonic acid; LO; lipoxygenase; cPLA2; cytosolic phospholipase A2; FLAP; 5-lipoxygenase-activating protein; cysLT; cysteinyl LT; BLT; B leukotriene r

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Paeoniflorin ameliorates cognitive dysfunction via regulating SOCS2/IRS-1 pathway in diabetic rats

Keywords: فسفینوزیتید 3-کیناز; Paeoniflorin; Diabetes; Cognitive dysfunction; SOCS2/IRS-1; Tau phosphorylation; Akt; protein kinase B; DE; diabetic encephalopathy; DM; diabetes mellitus; GSK-3β; glycogen synthase kinase-3β; IL-1β; interleukin-1β; IRS-1; insulin receptor substrate-1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Taming Tricky DSBs: ATM on duty

Keywords: فسفینوزیتید 3-کیناز; ATM; ataxia telangiectasia mutated; DSB; double strand breaks; DDR; DNA damage response; HR; homologous recombination; NHEJ; non-homologous end joining; PI3K; phosphoinositide 3-kinase; RNA pol II; RNA polymerase II; TAD; topologically associated domain;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Targeting energy metabolism of cancer cells: Combined administration of NCL-240 and 2-DG

Keywords: فسفینوزیتید 3-کیناز; ATP; adenosine triphosphate; HIF1-α; hypoxia inducible factor 1-α; GLUT; glucose transporter; DM-PIT-1; N-[(2-hydroxy-5-nitrophenyl)amino]carbonothioyl-3,5-dimethylbenzamide; PI3K; phosphoinositide 3-kinase; PIP3; phosphatidylinositol-3,4,5-triphosphate

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Phosphoinositide 3-kinase (PI3K) pathway inhibitors in solid tumors: From laboratory to patients

Keywords: فسفینوزیتید 3-کیناز; Solid tumors; Phosphoinositide 3-kinase; Inhibitors; Lessons; Laboratory; Clinical trial;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Acquired long QT syndrome and phosphoinositide 3-kinase

Keywords: فسفینوزیتید 3-کیناز; Long QT syndrome; phosphoinositide 3-kinase; sodium current; dofetilide; diabetes;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

15-Deoxy-Δ12,14-prostaglandin J2 induced neurotoxicity via suppressing phosphoinositide 3-kinase

Keywords: فسفینوزیتید 3-کیناز; 15-Deoxy-Δ12,14-prostaglandin J2; Phosphoinositide 3-kinase; Neurotoxicity; Cerebral cortex; Hippocampus; Memory retrieval; 15d-PGJ2; 15-Deoxy-Δ12,14-prostaglandin J2; CRTH2; Chemoattractant receptor-homologous molecule expressed on T-helper type 2 ce

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Adenosine isolated from Grifola gargal promotes glucose uptake via PI3K and AMPK signalling pathways in skeletal muscle cells

Keywords: فسفینوزیتید 3-کیناز; GLF; a low molecular weight fraction of aqueous extract from Grifola gargal; T2DM; type 2 diabetes mellitus; GLUT4; glucose transporter 4; IR; insulin receptor; PI3K; phosphoinositide 3-kinase; 2DG; 2-deoxyglucose; MEM; minimum essential medium; AR; adeno

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewScaffolding Function of PI3Kgamma Emerges from Enzyme's Shadow

Keywords: فسفینوزیتید 3-کیناز; PKA; protein kinase A; PI3K; phosphoinositide 3-kinase; PtdIns; phosphatidylinositols; RTK; receptor tyrosine kinase; GPCR; G-protein-coupled receptor; PIP3; PtdIns (3,4,5)-triphosphate; PI3Kγ; phosphoinositide 3-kinase γ; βAR; β-adrenergic receptor;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Signaling via G proteins mediates tumorigenic effects of GPR87

Keywords: فسفینوزیتید 3-کیناز; 7TM; seven transmembrane; AC; adenylate cyclase; BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; CREB; cAMP response element-binding protein; CSC; cancer stem cells; CysLTs; cysteinyl-leukotrienes; ELISA; Enzyme-linked immunosorbent assay

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

In situ detection of the activation of Rac1 and RalA small GTPases in mouse adipocytes by immunofluorescent microscopy following in vivo and ex vivo insulin stimulation

Keywords: فسفینوزیتید 3-کیناز; DMEM; Dulbecco's modified Eagle's medium; GAP; GTPase-activating protein; GEF; guanine nucleotide exchange factor; GST; glutathione S-transferase; HA; hemagglutinin; m-rac1-KO; muscle-specific rac1 knockout; Myr-p110α; myristoylated p110α; PBS; phosphat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of triazole aminopyrazines as a highly potent and selective series of PI3Kδ inhibitors

Keywords: فسفینوزیتید 3-کیناز; Phosphoinositide 3-kinase; PI3Kδ inhibitor; Aminopyrazine; Inflammation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Knocking down amygdalar PTP1B in diet-induced obese rats improves insulin signaling/action, decreases adiposity and may alter anxiety behavior

Keywords: فسفینوزیتید 3-کیناز; Amygdala; PTP1B; Insulin; Anxiety; Obesity; Akt; protein kinase B; ASO; antisense oligonucleotide; BAT; brown adipose tissue; CeA; central nucleus of the amygdala; CNS; central nervous system; EPM; elevated plus maze; ER; endoplasmatic reticulum; FI; food

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Honokiol, a potential therapeutic agent, induces cell cycle arrest and program cell death in vitro and in vivo in human thyroid cancer cells

Keywords: فسفینوزیتید 3-کیناز; DTC; differentiated thyroid cancer; PDTC; poorly differentiated thyroid cancer; ATC; anaplastic thyroid cancer; FTC; follicular thyroid carcinoma; PTC; papillary thyroid carcinoma; PI3K; phosphoinositide 3-kinase; NF-κB; nuclear factor kappa B; EGFR; epi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

AR-12 suppresses dengue virus replication by down-regulation of PI3K/AKT and GRP78

Keywords: فسفینوزیتید 3-کیناز; AR-12; Dengue; PI3K/AKT; GRP78; Antivirus; DENV; dengue virus; PI3K; phosphoinositide 3-kinase; GRP78; glucose-regulated protein 78; HSP; heat-shock protein;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Polyamine- and NADPH-dependent generation of ROS during Helicobacter pylori infection: A blessing in disguise

Keywords: فسفینوزیتید 3-کیناز; 8-OHdG; 8-hydroxy-2-deoxyguanosine; ABL1; ABL proto-oncogene 1; AhpC; alkyl hydroperoxide reductase; AKT1; V-Akt murine thymoma viral oncogene homolog 1; APEX1; endonuclease apurinic/apyrimidinic endodeoxyribonuclease 1; ARG1; arginase 1; ARG2; arginase 2

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Imaging flow cytometry and GST pulldown assays provide new insights into channel catfish leukocyte immune-type receptor-mediated phagocytic pathways

Keywords: فسفینوزیتید 3-کیناز; Phagocytosis; Immunoregulatory receptors; Intracellular signaling; Actin polymerization machinery; Imaging flow cytometry; Innate immunity; Channel catfish; Leukocyte immune-type receptors; IpLITR; channel catfish leukocyte immune-type receptor; CYT; cyto

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Compound Selectivity and Target Residence Time of Kinase Inhibitors Studied with Surface Plasmon Resonance

Keywords: فسفینوزیتید 3-کیناز; FDA; US Food and Drug Administration; EGFR; epidermal growth factor receptor; BTK; Bruton's tyrosine kinase; SPR; surface plasmon resonance; PI3K; phosphoinositide 3-kinase; SD; standard deviation; SE; standard error; PI3K; phosphoinositide 3-kinase; SPR;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Distribution of BDNF and TrkB isoforms in growing antler tissues of red deer

Keywords: فسفینوزیتید 3-کیناز; AACTB; actin-beta gene; B; bone; BDNF; brain-derived neurotrophic factor; BMPs; bone morphogenetic proteins; CA; non-mineralized cartilage; CP; chondroprogenitors; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; IGF-I; II insulin-lik

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study

Keywords: فسفینوزیتید 3-کیناز; Activated phosphoinositide 3-kinase δ syndrome; p110δ-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency; phosphoinositide 3-kinase δ; PIK3CD gene; bronchiectasis; immunodeficiency; hematopoietic stem cell transplanta

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase-mediated suppression of histone deacetylase 2

Keywords: فسفینوزیتید 3-کیناز; Severe asthma; corticosteroids; airway hyperresponsiveness; miR-21; PI3 kinase; histone deacetylase 2; Chlamydia species; Haemophilus influenzae; influenza; respiratory syncytial virus; AAD; Allergic airway disease; AHR; Airway hyperresponsiveness; Ant-21

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

8-Oxoguanine DNA glycosylase1-driven DNA repair-A paradoxical role in lung aging

Keywords: فسفینوزیتید 3-کیناز; 8-oxoG; 7,8-dihydro-8-oxoguanine; 8-oxodG; 7,8-dihydro-8-oxo-2′-deoxyguanosine; BER; base excision repair; DNA dsbs; double strand breaks; DNA ssbs; single strand breaks; GEF; guanine nucleotide exchange factor; GOrilla; Gene Ontology enrichment analysi

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Roles for RACK1 in cancer cell migration and invasion

Keywords: فسفینوزیتید 3-کیناز; EMT; Epithelial to mesenchymal transition; FAK; Focal adhesion kinase; MMPs; Matrix metalloproteases; IGF-I; Insulin-like Growth Factor-1; IGF-IR; Insulin-like Growth Factor-1 Receptor; PP2A; Protein Phosphatase 2A; PI3K; Phosphoinositide 3-kinase; PI(3,4

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Theaflavins from black tea affect growth, development, and motility in Dictyostelium discoideum

Keywords: فسفینوزیتید 3-کیناز; Polyphenols; Theaflavins; Dictyostelium; Cell motility; Development; BTE; black tea extract; EGCG; epigallocatechin gallate; PI3K; phosphoinositide 3-kinase; PIP3; phosphatidylinositol (3,4,5)-trisphosphate; Theaflavin (PubChem CID: 114777); Theaflavin 3,

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Genome-wide DNA methylation variation in maternal and cord blood of gestational diabetes population

Keywords: فسفینوزیتید 3-کیناز; GDM; gestational diabetes mellitus; DM; diabetes mellitus; BMI; body mass index; ADIPOQ; adiponectin gene; CpG; cytosine guanine dinucleotide; OGTT; oral glucose tolerance test; IADPSG; international association of diabetes and pregnancy study groups; IPA

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

S-nitrosylation of the IGF-1 receptor disrupts the cell proliferative action of IGF-1

Keywords: فسفینوزیتید 3-کیناز; Insulin-like growth factor; Nitric oxide; S-Nitrosylation; Signal transduction; ERK; extracellular signal-regulated protein kinase; IGF-1; insulin-like growth factor-1; IGF-1R; insulin-like growth factor-1 receptor; IRS; insulin receptor substrate; MAPK;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

HSPA5 Gene encoding Hsp70 chaperone BiP in the endoplasmic reticulum

Keywords: فسفینوزیتید 3-کیناز; aa; amino acid; ATF6; activating transcription factor 6; BIK; BCL2-interacting killer; BiP; binding immunoglobulin protein; CD86; cluster of differentiation 86; CHOP; CCAAT-enhancer-binding protein homologous protein; Derlin-1; degradation in ER protein 1

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells

Keywords: فسفینوزیتید 3-کیناز; Regulatory T cells; phosphatases; phosphoinositide 3-kinase; PTEN; PH domain leucine-rich repeat protein phosphatase; PHTS; immunologic synapse; autoimmunity; APC; Allophycocyanin; CS; Cowden syndrome; CTLA-4; Cytotoxic T lymphocyte-associated antigen 4

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Vitamin D supplementation inhibits oxidative stress and upregulate SIRT1/AMPK/GLUT4 cascade in high glucose-treated 3T3L1 adipocytes and in adipose tissue of high fat diet-fed diabetic mice

Keywords: فسفینوزیتید 3-کیناز; High glucose; Oxidative stress; Vitamin D; SIRT1/AMPK/IRS1/GLUT4; Glucose metabolism; 1,25(OH)2D3; 1,25-dihydroxyvitamin D3; AKT; serine/threonine protein kinase; AMPK; AMP activated protein kinase; GLUT1; glucose transporter 1; GLUT4; glucose transporter

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis

Keywords: فسفینوزیتید 3-کیناز; YAP1; YES-Associated Protein; WWTR1; TAZ; AJ; adherens junction; AMOT; angiomotin; CC; cholangiocardinoma; HB; hepatoblastoma; HCC; hepatocellular carcinoma; HepSC; hepatic stellate cell; LATS; large tumor suppressor kinase; PI3K; phosphoinositide 3-kinas

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Anti-inflammatory effect of Cortex Eucommiae via modulation of the toll-like receptor 4 pathway in lipopolysaccharide-stimulated RAW 264.7 macrophages

Keywords: فسفینوزیتید 3-کیناز; CE; Cortex Eucommiae; LPS; lipopolysaccharide; HPLC; high-performance liquid chromatography; RT-PCR; reverse transcriptase-polymerase chain reaction; IC50; inhibitory concentration of 50%; TLR-4; toll-like receptor 4; Myd88; myeloid differentiation primar

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Choline Kinase α Mediates Interactions Between the Epidermal Growth Factor Receptor and Mechanistic Target of Rapamycin Complex 2 in Hepatocellular Carcinoma Cells to Promote Drug Resistance and Xenograft Tumor Progression

Keywords: فسفینوزیتید 3-کیناز; Liver Cancer; Signal Transduction; Tumorigenesis; Oncogene; AKT; v-akt murine thymoma viral oncogene homolog; CHKA; choline kinase α; EGFR; epidermal growth factor receptor; ERK; extracellular regulated kinase; GFP; green fluorescent protein; HCC; hepato

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

HDL inhibits saturated fatty acid mediated augmentation of innate immune responses in endothelial cells by a novel pathway

Keywords: فسفینوزیتید 3-کیناز; Saturated fatty acid; HDL; Inflammation; Cell signaling; MAP kinase; ATF3; LPS; lipopolysaccharide; TLRs; Toll-like receptors; PA; palmitic acid; HAECs; human aortic endothelial cells; MAPKs; mitogen-activated protein kinases; PI3K; Phosphoinositide 3-kin

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

AKT-dependent phosphorylation of the SAM domain induces oligomerization and activation of the scaffold protein CNK1

Keywords: فسفینوزیتید 3-کیناز; ARF; ADP ribosylation factor; CNK; connector enhancer of KSR; ERK; extracellular signal-regulated protein kinase; EGF; epidermal growth factor; GF; growth factor; IGF; insulin-like growth factor; MAPK; mitogen-activated protein kinase; MEK; MAPK/ERK kinas

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

The roles of subcellularly located EGFR in autophagy

Keywords: فسفینوزیتید 3-کیناز; AMPK; AMP-activated protein kinase; ATG; autophagy-related; BCL2; B-cell lymphoma 2; BCL2L1; BCL2 like 1; BNIP3; BCL2/Adenovirus E1B-binding protein Nip3; CME; clathrin-mediated endocytosis; cytoSTAT3; cytoplasmic STAT3; Dsbs; double strand breaks; ECD; e

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Redox regulation of the tumor suppressor PTEN by the thioredoxin system and cumene hydroperoxide

Keywords: فسفینوزیتید 3-کیناز; AP-1; activator protein-1; DMEM; Dulbecco's modified Eagle's medium; DTT; dithiothreitol; FBS; fetal bovine serum; Grx; glutaredoxin; GSH; glutathione; HPLC; high- performance liquid chromatography; HRP; horseradish peroxidase; MEFs; mouse embryonic fibro

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Benzo[a]pyrene-7,8-diol-9,10-epoxide suppresses the migration and invasion of human extravillous trophoblast HTR-8/SVneo cells by down-regulating MMP2 through inhibition of FAK/SRC/PI3K/AKT pathway

Keywords: فسفینوزیتید 3-کیناز; ANOVA; analysis of variance; BaP; benzo[a]pyrene; BPDE; benzo[a]pyren-7,8-dihydrodiol-9,10-epoxide; DMSO; dimethylsulfoxide; ECM; extracellular matrix; EVT; extravillous trophoblast; EGF; epidermal growth factor; eNOS; endothelial nitric oxide synthase; F

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Heat shock protein 22 (HSPB8) reduces the migration of hepatocellular carcinoma cells through the suppression of the phosphoinositide 3-kinase (PI3K)/AKT pathway

Keywords: فسفینوزیتید 3-کیناز; HSP; heat shock protein; HCC; hepatocellular carcinoma; TGF; transforming growth factor; HGF; hepatocyte growth factor; PI3K; phosphoinositide 3-kinase; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kinase; siRNA; small inter

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2017 سفارش ترجمه

Sulforaphane inhibits platelet-derived growth factor-induced vascular smooth muscle cell proliferation by targeting mTOR/p70S6kinase signaling independent of Nrf2 activation

Keywords: فسفینوزیتید 3-کیناز; Sulforaphane (PubChem CID: 5350); Dimethyl Sulfoxide (PubChem CID: 679); ARE; antioxidant response element; CREB; cAMP-response element-binding protein; DAB; diaminobenzidine; DMSO; dimethyl sulfoxide; 4E-BP1; eukaryotic translation initiation factor 4E-b

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2017 سفارش ترجمه