دانلود مقالات ISI درباره فسفینوزیتید 3-کیناز + ترجمه فارسی

Antitumor activity of BJ-1207, a 6-amino-2,4,5-trimethylpyridin-3-ol derivative, in human lung cancer

Keywords: فسفینوزیتید 3-کیناز; Aminopyridin-3-ols; Non-small cell lung cancer; NADPH oxidase; Stem cell factor; Transforming growth factor-α; Akt; protein kinase B; CAM; chick chorioallantoic membrane; c-KIT; cellular homolog of the feline sarcoma viral oncogene v-kit; DPPH; 1,1-diphe

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Mesenchymal stem cells drive paclitaxel resistance in ErbB2/ErbB3-coexpressing breast cancer cells via paracrine of neuregulin 1

Keywords: فسفینوزیتید 3-کیناز; Mesenchymal stem cells (MSCs); Paclitaxel-resistance; ErbB2/ErbB3-coexpressing breast cancer; Tumor microenvironment; hUC-MSCs; Human umbilical cord mesenchymal stem cells; NRG-1; neuregulin 1; PI-3K; phosphoinositide 3-kinase; qRT-PCR; real-time quantita

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Design and synthesis of alkyl substituted pyridino[2,3-D]pyrimidine compounds as PI3Kα/mTOR dual inhibitors with improved pharmacokinetic properties and potent in vivo antitumor activity

Keywords: فسفینوزیتید 3-کیناز; PI3K; phosphoinositide 3-kinase; mTOR; mammalian target of rapamycin; TSC; tuberous sclerosis; DDQ; 2,3-dicyano-5,6-dichlorobenzoquinone; THF; tetrahydrofuran; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide; MRT; mean retention time; PI3Kα/

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Titanium dioxide nanoparticles induce human eosinophil adhesion onto endothelial EA.hy926 cells via activation of phosphoinositide 3-kinase/Akt cell signalling pathway

Keywords: فسفینوزیتید 3-کیناز; NP; nanoparticle; PI3K; phosphoinositide 3-kinase; VAA-I; viscum album agglutinin-I; DLS; dynamic light scattering; GM-CSF; granulocyte macrophage-colony stimulating factor; Nanoparticles; Eosinophils; Adhesion; Cell signalling;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Pharmacological effects and potential therapeutic targets of DT-13

Keywords: فسفینوزیتید 3-کیناز; ADP; adenosine diphosphate; Akt; protein kinsase B; ALT; alanine transaminase; APD; action potential duration; AST; aspartate transaminase; Atg; autophagocytosis associated protein; CCR5; C, C chemokine receptor type 5; CXCR4; C-X-C chemokine receptor typ

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Targeting AgRP neurons to maintain energy balance: Lessons from animal models

Keywords: فسفینوزیتید 3-کیناز; ARC; arcuate nucleus; POMC; proopiomelanocortin; GABA; γ-aminobutyric acid; LHA; lateral hypothalamic nucleus; VHA; ventromedial nuclei; PVH; paraventricular; PBN; parabrachial nuclei; MSH; melanocyte-stimulating hormone; CART; amphetamine-stimulating ho

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Phoenixin participated in regulation of food intake and growth in spotted scat, Scatophagus argus

Keywords: فسفینوزیتید 3-کیناز; Pnx; phoenixin; ghrhr; growth hormone-releasing hormone receptor; gh; growth hormone; ghr; growth hormone receptor; Igf; insulin-like growth factor; Ghrh; growth hormone-releasing hormone; PVN; paraventricular nucleus; Arc; arcuate nucleus; VMH; ventromed

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Anandamide inhibits FcεRI-dependent degranulation and cytokine synthesis in mast cells through CB2 and GPR55 receptor activation. Possible involvement of CB2-GPR55 heteromers

Keywords: فسفینوزیتید 3-کیناز; AEA; anandamide; BMMCs; bone marrow-derived mast cells; FcεRI; high affinity IgE receptor; 2-AG; 2-arachidonoylglycerol; DNP-HSA; dinitrophenol coupled to human serum albumin (antigen); IgE; immunoglobulin E; TNF; Tumor Necrosis Factor; IL; interleukin;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

The role of the ShcD and RET interaction in neuroblastoma survival and migration

Keywords: فسفینوزیتید 3-کیناز; Akt,; Protein kinase B;; ALK,; Anaplastic Lymphoma Kinase; CMV,; Cytomegalovirus; DMEM,; Dulbecoo Modified Eagle's Medium;; DNA,; Deoxyribonucleic Acid; ECL,; Enhanced Chemiluminescence;; EGF,; Epidermal Growth Factor;; EGFR,; Epidermal Growth Factor Rece

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

eIF4E Phosphorylation in Prostate Cancer

Keywords: فسفینوزیتید 3-کیناز; eIF4E; eukaryotic translation initiation factor 4E; mTOR; mammalian target of rapamycin; PCa; prostate cancer; Mnk; mitogen activated protein kinase interacting protein kinase; ADT; androgen deprivation therapy; MAPK; mitogen-activated protein kinase; CRP

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Ubiquitination and SUMOylation in the chronic inflammatory tumor microenvironment

Keywords: فسفینوزیتید 3-کیناز; Inflammation-associated cancer; Ubiquitin-proteasome system (UPS); Small ubiquitin-like modifier (SUMO); Tumor microenvironment; Cytokine profile; Transcription factors; 15d-PGJ2; 15-Deoxy-Delta-12,14-prostaglandin J2; AR; androgen receptor; Ala; alanine;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Expression of PI3K Signaling Associated with T Cells in Psoriasis Is Inhibited by Seletalisib, a PI3Kδ Inhibitor, and Is Required for Functional Activity

Keywords: فسفینوزیتید 3-کیناز; CFSE; carboxyfluorescein diacetate succinimidyl ester; PBMC; peripheral blood mononuclear cell; PI3K; phosphoinositide 3-kinase; pS6; phosphorylated ribosomal protein S6;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Survivin-targeting miR-542-3p overcomes HER3 signaling-induced chemoresistance and enhances the antitumor activity of paclitaxel against HER2-overexpressing breast cancer

Keywords: فسفینوزیتید 3-کیناز; HER3; Survivin; miRNA; Paclitaxel resistance; Breast cancer; RTKs; Receptor tyrosine kinases; PI-3K; Phosphoinositide 3-kinase; CHX; Cycloheximide; ELISA; Enzyme-linked immunosorbent assay; IHC; Immunohistochemistry; i.p.; Intraperitoneal;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Designer Approaches for G Protein-Coupled Receptor Modulation for Cardiovascular Disease

Keywords: فسفینوزیتید 3-کیناز; biased ligands; G protein-coupled receptor kinases; G protein-coupled receptors; AR; adrenergic receptor; AT1R; angiotensin II type 1A receptor; CRF; corticotropin-releasing factor; EGFR; epidermal growth factor receptor; ERK1/2; extracellular signal-

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Berberine confers neuroprotection in coping with focal cerebral ischemia by targeting inflammatory cytokines

Keywords: فسفینوزیتید 3-کیناز; TTC; 23,5-triphenyltetrazolium chloride; MCAO; middle cerebral artery occlusion; p-AKT; phosphorylated Protein kinase B; pGSK; phosphorylated Glycogen synthase kinase; pCREB; phosphorylated cAMP response element-binding protein; NF-κB; nuclear factor-κB

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

IL-6 knockout mice are protected from cocaine-induced kindling behaviors; possible involvement of JAK2/STAT3 and PACAP signalings

Keywords: فسفینوزیتید 3-کیناز; Cocaine-induced kindling (convulsive) behaviors; Interleukin-6 knockout mice; Pituitary adenylate cyclase-activating polypeptide; JAK2/STAT3; Tumor necrosis factor-α knockout mice; Hippocampus; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IL-6; inter

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

GLUT1 protects prostate cancer cells from glucose deprivation-induced oxidative stress

Keywords: فسفینوزیتید 3-کیناز; 2DG; 2-deoxyglcuose; AMPK; AMPK-activated protein kinase; AR; Androgen Receptor; CAT; Catalase; DHA; Dehydroascorbic Acid; G6PG; Glucose-6-phosphate dehydrogenase; GPX; Glutathione peroxidase; GSH; Reduced glutathione; GSSG; Oxidized glutathione; HTLV; Hu

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

Correlation between telomerase and mTOR pathway in cancer stem cells

Keywords: فسفینوزیتید 3-کیناز; CSCs; cancer stem cells; mTOR; mammalian target of rapamycin; PI3K; phosphoinositide 3-kinase; AKT; serine/threonine kinase 1; hTERT; human telomerase reverse transcriptase; TERC; telomerase RNA component; GBM; glioblastoma multiforme; TRF1; telomeric rep

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

The mechanism of tumour cell death by metal-based anticancer drugs is not only a matter of DNA interactions

Keywords: فسفینوزیتید 3-کیناز; 15-LOX-1; 15-lipoxygenase; AIF; apoptosis inducing factor; APC; adenomatous polyposis coli; AKT or PKB; protein kinase B; ATG16L2; autophagy related 16 like 2; AUC; area under the curve; Bad; Bcl-2 associated death promoter; Bcl-2; B-cell lymphoma 2; Bcl-

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

A splice junction-targeted CRISPR approach (spJCRISPR) reveals human FOXO3B to be a protein-coding gene

Keywords: فسفینوزیتید 3-کیناز; aa; amino acid(s); bp; base pairs; Cas9; CRISPR associated protein 9; cDNA; DNA complementary to RNA; CRISPR; Clustered Regularly Interspaced Short Palindromic Repeats; DMSO; dimethylsulfoxide; Dox; doxycycline; dsDNA; double stranded DNA; FOXO; forkhead

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Xanthone-rich extract from Gentiana dinarica transformed roots and its active component norswertianin induce autophagy and ROS-dependent differentiation of human glioblastoma cell line

Keywords: فسفینوزیتید 3-کیناز; Gentiana dinarica transformed roots; Xanthone; Norswertianin; Glioblastoma; Cell differentiation; Autophagy; GBM; Glioblastoma multiforme; Atg; autophagy-related proteins; mTOR; mammalian target of rapamycin; PI3K; phosphoinositide 3-kinase; AMPK; AMP-act

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Understanding the biology of HER3 receptor as a therapeutic target in human cancer

Keywords: فسفینوزیتید 3-کیناز; Ab; antibody; ADCC; antibody-dependent cell-mediated cytotoxicity; EGFR; epidermal growth factor receptor; EMT; epithelial-mesenchymal transition; FDA; Food and Drug Administration; HER; Human epidermal growth factor receptor; HRG; heregulin; IGF-1R; insu

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

High frequencies of asymptomatic Epstein-Barr virus viremia in affected and unaffected individuals with CTLA4 mutations

Keywords: فسفینوزیتید 3-کیناز; ALPS; autoimmune lymphoproliferative syndrome; APDS; activated phosphoinositide 3-kinese δ syndrome; BENTA; B-cell expansion with nuclear factor-κB and T-cell anergy; EBV; Epstein-Barr virus; ITP; immune thrombocytopenic purpura; LCLs; lymphoblastoid ce

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Phosphoinositide 3-kinase p110α negatively regulates thrombopoietin-mediated platelet activation and thrombus formation

Keywords: فسفینوزیتید 3-کیناز; Phosphoinositide 3-kinase; Platelets; Knockout mice; Thrombopoietin; Thrombosis;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Vanadium: History, chemistry, interactions with α-amino acids and potential therapeutic applications

Keywords: فسفینوزیتید 3-کیناز; 2,2′-bipy; 2,2-bipyridine; 6-mepic; 6-methylpicolinic acid; acac; acetylacetone; Ad; adenosine; Ala; alanine; Ala-Gly; alanylglycine; Ala-His; alanylhistidine; Ala-Ser; alanylserine; Asp; aspartic acid; BEOV; bis(ethylmaltolate)oxovanadium(IV); Cys; cys

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Diabetes mellitus and Alzheimer's disease: GSK-3β as a potential link

Keywords: فسفینوزیتید 3-کیناز; 3xTg; triple-transgenic; Aβ; β-amyloid; AD; Alzheimer's disease; ADAS-cog; Alzheimer's Disease Assessment Scale-cognitive subscale; Akt; protein kinase B; APP; amyloid precursor protein; CREB; cAMP-response element binding protein; DM; diabetes mell

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Bavachalcone from Cullen corylifolium induces apoptosis and autophagy in HepG2 cells

Keywords: فسفینوزیتید 3-کیناز; C. corylifolium; Bavachalcone; Apoptosis; Cell cycle; Autophagy; CCE; Cullen corylifolium ethanol extract; HCC; hepatocellular carcinoma; NAFLD; Nonalcoholic fatty liver disease; Bax; bcl-2-associated X protein; Bcl-2; b-cell lymphoma 2; Bid; BH3 interact

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Reduced substrate stiffness promotes M2-like macrophage activation and enhances peroxisome proliferator-activated receptor γ expression

Keywords: فسفینوزیتید 3-کیناز; PPARγ; Peroxisome proliferator-activated receptor γ; ECM; extracellular matrix; TGF-β; transforming growth factor-β; PI3K; phosphoinositide 3-kinase; F-actin; filamentous-actin; TNF-α; tumor necrosis factor-α; IL; interleukin; FCS; fetal calf serum;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Phosphoinositide 3-kinase pathways and autophagy require phosphatidylinositol phosphate kinases

Keywords: فسفینوزیتید 3-کیناز; Phosphoinositide; Phosphatidylinositol phosphate kinase; Phosphatidylinositol 4,5-bisphosphate; Phosphoinositide 3-kinase; Autophagy; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Unravelling the role of fatty acid metabolism in cancer through the FOXO3-FOXM1 axis

Keywords: فسفینوزیتید 3-کیناز; Fatty acids; Cancer; Lipid metabolism; FOXO3; FOXM1; AKT/PI3K pathway; AKT; protein kinase B; AMPK; adenosine monophosphate-activated-activated protein kinase; APN; adiponectin; CoA; coenzyme A; CPT1; carnitine palmitoyltransferase 1; DHA; docosahexaenoic

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

FOXOs in cancer immunity: Knowns and unknowns

Keywords: فسفینوزیتید 3-کیناز; 2B4; CD244 molecule; AKT or PKB; protein kinase B; APCs; antigen-presenting cells; ARG1; arginase 1; BEC; blood endothelial cell; BLNK; B cell Linker protein; BMP; bone morphogenetic protein; BTK; Bruton tyrosine kinase; C/EBP; CCAAT/enhancer-binding prot

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy in breast cancer

Keywords: فسفینوزیتید 3-کیناز; 7-AAD; 7-amino-actinomycin D; ABC; ATP-binding cassette; AEC; 3-amino-9-ethyl carbazole; ATD; acute toxicity determination; Atg5; autophagy protein 5; ATP; adenosine-5′-triphosphate; BCL-2; B-cell lymphoma 2; Bip/GRP78; binding immunoglobulin protein/78

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition

Keywords: فسفینوزیتید 3-کیناز; Akt; protein kinase B; Bax; Bcl-2 associated X; Bcl-2; B-cell lymphoma 2; DAPI; 4′,6-diamidino-2-phenylindole; DDP; cisplatin; EMT; epithelial-to-mesenchymal transition; FBS; fetal bovine serum; GAPDH; glyceraldeyde 3-phosphate dehydrogenase; HRP; horse

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Systemic L-buthionine-S-R-sulfoximine administration modulates glutathione homeostasis via NGF/TrkA and mTOR signaling in the cerebellum

Keywords: فسفینوزیتید 3-کیناز; GSH; Cysteine transport; NGF; mTOR; Redox; Cerebellum; 4F2hc; 4F2 cell surface antigen; BBB; blood-brain barrier; BSO; L-buthionine-S-R-sulfoximine; CNS; central nervous system; DAPI; 4′,6-diamidino-2-phenylindole DTPA; diethylenetriamine penta-acetic a

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

GS-9620 inhibits enterovirus 71 replication mainly through the NF-κB and PI3K-AKT signaling pathways

Keywords: فسفینوزیتید 3-کیناز; Enterovirus 71; Hand; Foot and mouth disease; GS-9620; NF-κB and PI3K-AKT signaling pathways; EV71; Human enterovirus 71; TLR7; Toll-like receptor 7; NF-κB; nuclear factor kappa B; PI3K; phosphoinositide 3-kinase; hpi; hours post infection;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Sulfiredoxin-1 enhances cardiac progenitor cell survival against oxidative stress via the upregulation of the ERK/NRF2 signal pathway

Keywords: فسفینوزیتید 3-کیناز; SRXN1; sulfiredoxin-1; ALDH; aldehyde dehydrogenase; CoPP; Cobalt protoporphyrin; ΔΨm; mitochondrial membrane potential; BCL2; B-cell CLL/lymphoma 2; BCL-XL; BCL2-like 1; FACS; fluorescence-activated cell sorter; ALDHbr-hCPCs; aldehyde dehydrogenase bri

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Efferocytosis in atherosclerotic lesions: Malfunctioning regulatory pathways and control mechanisms

Keywords: فسفینوزیتید 3-کیناز; ABC; ATP-binding cassette; ABCA1; ATP-binding membrane cassette transporter A1; ABCG1; ATP binding cassette transporter G1; ABCA7; ATP-binding cassette transporters A7; Abs; Antibodies; ACs; Apoptotic cells; AICAR; 5-aminoimidazole-4-carboxamide-1-β-d-ri

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

The effects of wild bitter gourd fruit extracts on ICAM-1 expression in pulmonary epithelial cells of C57BL/6J mice and microRNA-221/222 knockout mice: Involvement of the miR-221/-222/PI3K/AKT/NF-κB pathway

Keywords: فسفینوزیتید 3-کیناز; WBGE; Inflammation; ICAM-1; miR-221/-222; PI3K/AKT; NF-κB; AKT; protein kinase B; C; Control; CH; charantin; COPD; chronic obstructive pulmonary disease; DMEM; Dulbecco's modified Eagle's medium; ERK; extracellular-signal-regulated kinase; ICAM; intercel

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Insulin-signaling Pathway Regulates the Degradation of Amyloid β-protein via Astrocytes

Keywords: فسفینوزیتید 3-کیناز; ACE; angiotensin-converting enzyme; AD; Alzheimer's disease; Aß; amyloid ß-protein; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; ECE; endothelin-converting enzyme; EDTA; ethylenediaminetetraacetic acid; EGCG; epigallocatechi

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

PI3K pathway in prostate cancer: All resistant roads lead to PI3K

Keywords: فسفینوزیتید 3-کیناز; CRPC; castration-resistant prostate cancer; ADT; androgen deprivation therapy; PI3K; phosphoinositide 3-kinase; AR; androgen receptor; PTEN; phosphatase and tensin homologue deleted on chromosome 10; INPP4B; inositol polyphosphate 4-phosphatase type II; P

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of bisphenol A on metabolism and evidences of a mode of action mediated through endocrine disruption

Keywords: فسفینوزیتید 3-کیناز; Bisphenol A; BPA; Endocrine disruption; Obesity; Type 2 diabetes; Insulin; BAT; brown adipose tissue; BMI; body mass index; bw; body weight; DES; diethylstilbestrol; DM; Diabete mellitus; ED; endocrine disruptor; eGFR; estimated glomerular filtration; ERR

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

A change in structural integrity of c-Kit mutant D816V causes constitutive signaling

Keywords: فسفینوزیتید 3-کیناز; JAK; Janus kinase; JM region; juxtamembrane region; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; MD; molecular dynamics; MIHC; Myb-immortalized haemopoietic cells; WT; wild-type c-Kit; WTp; wild-type phosphorylated c-Kit; MT_D816V

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Ecdysteroidogenesis and development in Heliothis virescens (Lepidoptera: Noctuidae): Focus on PTTH-stimulated pathways

Keywords: فسفینوزیتید 3-کیناز; PG; prothoracic gland; BE; brain equivalent; PTTH; prothoracicotropic hormone; MAPK; mitogen-activated protein kinase; PI3K; phosphoinositide 3-kinase; Akt; protein kinase B; TOR; target of rapamycin; EIA; enzyme immunoassay; 4E-BP; translational represso

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Neural progenitors derived from Tuberous Sclerosis Complex patients exhibit attenuated PI3K/AKT signaling and delayed neuronal differentiation

Keywords: فسفینوزیتید 3-کیناز; TSC; Tuberous Sclerosis Complex; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; LOH; loss of heterozygosity; iPSCs; induced pluripotent stem cells; NPCs; neural progenitor cells; PI3K; phosphoinositide 3-kinase; SENs; subependymal nodules; S

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Stimulation of the adenosine A3 receptor, not the A1 or A2 receptors, promote neurite outgrowth of retinal ganglion cells

Keywords: فسفینوزیتید 3-کیناز; Adenosine receptors; Neuroregeneration; Glaucoma; Akt; 2-Cl-IB-MECA; IOP; intraocular pressure; RGC; retinal ganglion cell; NTG; normal tension glaucoma; AC; adenylyl cyclase; cAMP; cyclic adenosine monophosphate; PI3K; phosphoinositide 3-kinase; AdoR; ad

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Astaxanthin: A mechanistic review on its biological activities and health benefits

Keywords: فسفینوزیتید 3-کیناز; Astaxanthin (PubChem CID: 5368397); Beta-Carotene (PubChem CID: 5280489); Beta-Cryptoxanthin (PubChem CID: 5281235); Canthaxanthin (PubChem CID: 5281227); Lutein (PubChem CID: 5281243); Zeaxanthin (PubChem CID: 5280899); Alpha-Tocopherol (PubChem CID: 149

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Drosophila as a model for ageing

Keywords: فسفینوزیتید 3-کیناز; 4EBP; translation initiation factor 4E binding protein; AMPK; AMP activated protein kinase; AOP; anterior open; ATF4; activating transcription factor 4; CHOP; C/EBP homologous protein; CR; calorie restriction; DR; dietary restriction; eIF; eukaryotic tran

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

The novel, catalytic mTORC1/2 inhibitor PQR620 and the PI3K/mTORC1/2 inhibitor PQR530 effectively cross the blood-brain barrier and increase seizure threshold in a mouse model of chronic epilepsy

Keywords: فسفینوزیتید 3-کیناز; Epilepsy; Rapamycin; Everolimus; Pharmacokinetics; Tolerability; Levetiracetam; AKT; protein kinase B; ASD; anti-seizure drug; 4E-BP1; initiation factor 4E binding protein; HPβCD; hydroxypropyl-ß-cyclodextrin; MTD; maximal tolerated dose; MES-T; maximal

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Role of endogenous and exogenous nitric oxide, carbon monoxide and hydrogen sulfide in HCT116 colon cancer cell proliferation

Keywords: فسفینوزیتید 3-کیناز; 3-MST; 3-mercaptopyruvate sulfurtransferase; 3B7NI; 3-bromo-7-nitroindazole; AOAA; aminooxyacetic acid; CBS; cystathionine-β-synthase; CO; carbon monoxide; CSE; cystathionine gamma lyase; eNOS; endothelial nitric oxide synthase; nNOS; neuronal nitric oxi

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Atorvastatin impaired glucose metabolism in C2C12 cells partly via inhibiting cholesterol-dependent glucose transporter 4 translocation

Keywords: فسفینوزیتید 3-کیناز; ABC; ATP-binding cassette; Akt; Protein kinase B; AUC; area under the concentrationtime curve; BW; body weight; CMC; carboxyl methyl cellulose; ERK; extracellular-regulated protein kinase; GCK; glucokinase; GLUT2; glucose transporter 2; GLUT4; glucose tra

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2018 سفارش ترجمه