Keywords: فسفروتیوات; ASO; antisense oligonucleotides; BANCR; BRAF-activated non-coding RNA; CCAT1-L; colorectal cancer associated transcript 1-long isoform; cET; constrained EThyl; EMT; epithelial to mesenchymal transition; ERV; endogenous retroviral sequence; FDA; food and d
مقالات ISI فسفروتیوات (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: فسفروتیوات; Phosphorothioate; Phosphate; Triester; Diester; Hydrolysis; Methanolysis;
Keywords: فسفروتیوات; 8-oxo-dGTP; 8-Oxo-2â²-deoxyguanosine-5â²-triphosphate; AAV; Adeno-associated virus; ABI-REC; Asymmetric Bridge PCR with Intramolecular Homologous Recombination; bp; Base pairs; CAST; Combinatorial Active-Site Saturation Test; CPEC; Circular Polymerase E
Development of orally-deliverable DNA hydrogel by microemulsification and chitosan coating
Keywords: فسفروتیوات; CpG; cytosine-phosphate-guanine; ODN; oligodeoxynucleotide; Dgel-MS; DNA hydrogel microsphere; Cs-Dgel; chitosan-coated DNA hydrogel; Cs-Dgel-MS; chitosan-coated DNA hydrogel microsphere; mDgel; modified DNA hydrogel; TLR9; Toll-like receptor 9; Polypodna
Separation of small interfering RNA stereoisomers using reversed-phase ion-pairing chromatography
Keywords: فسفروتیوات; Small interfering RNA; Diastereomer; Stereoisomer; Phosphorothioate; Desulfurization; Ion-pairing reversed-phase liquid chromatography;
Engineering Novel Molecular Beacon Constructs to Study Intracellular RNA Dynamics and Localization
Keywords: فسفروتیوات; 2â²-O-methyl RNA; Phosphorothioate; Molecular beacon; RNA dynamics; Single-molecule RNA imaging;
Photoaffinity electrophoretic mobility shift assay using photoreactive DNA bearing 3-trifluoromethyl-3-phenyldiazirine in its phosphate backbone
Keywords: فسفروتیوات; Diazirine; Octamer motif; Phosphorothioate; Photo-cross-linking; Proteomic analysisUV, ultraviolet; EMSA, electrophoretic mobility shift assay; SDS–PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis; DMSO, dimethyl sulfoxide; HPLC, high-perfo
Single-molecule detection and tracking of RNA transcripts in living cells using phosphorothioate-optimized 2â²-O-methyl RNA molecular beacons
Keywords: فسفروتیوات; Molecular beacons; 2â²-O-methyl RNA; Phosphorothioate; RNA imaging; Single-molecule detection; RNA dynamics;
Antisense molecules: AÂ new class of drugs
Keywords: فسفروتیوات; Clinical trial; antisense; small interfering RNA; DNAzyme; therapy; ALS; Amylotrophic lateral sclerosis; AMD; Age-related macular degeneration; CMV; Cytomegalovirus; CNV; Choroidal neovascularization; CVD; Cardiovascular disease; DMD; Duchenne muscular dy
Self-assembling DNA hydrogel-based delivery of immunoinhibitory nucleic acids to immune cells
Keywords: فسفروتیوات; AFM; atomic force microscopy; ANOVA; one-way analysis of variance; CpG DNA; DNA containing unmethylated cytosine-phosphate-guanine dinucleotide; DLS; dynamic light scattering; ELISA; enzyme linked immunosorbent assay; INH-ODN; immunoinhibitory oligodeoxyn
Site directed nitroxide spin labeling of oligonucleotides for NMR and EPR studies
Keywords: فسفروتیوات; Nitroxide; Phosphorothioate; Nuclear magnetic resonance spectroscopy; Electron paramagnetic resonance spectroscopy; Paramagnetic relaxation enhancement;
Bioconjugates for targeted delivery of therapeutic oligonucleotides
Keywords: فسفروتیوات; ASO; antisense oligonucleotide; CDM; carboxylated dimethyl maleic acid; CPP; cell penetrating peptide; DPC; dynamic polyconjugate; ED50; median effective dose; GalNAc; N-acetylgalactosamine; LNP; lipid nanoparticle; NP; nanoparticle; ON; oligonucleotide;
Preclinical and clinical development of siRNA-based therapeutics
Keywords: فسفروتیوات; 2â²-OMe; 2â²-O-methyl; 2â²-F; 2â²-fluoro; CH/TA; chitosan/thioaptamer; DOPC; 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine; DOTAP; 1,2-dioleoyl-3-trimethylammonium-propane; DOTMA; N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methyl sulfate; E
Terminally modified, short phosphorothioate oligonucleotides as inhibitors of gene expression in cells
Keywords: فسفروتیوات; Phosphorothioate; Chemical modification; Terminal modifier; Oligonucleotide; Antisense
Phosphorothioate modification of the TLR9 ligand CpG ODN inhibits poly(I:C)-induced apoptosis of hepatocellular carcinoma by entry blockade
Keywords: فسفروتیوات; TLR; Tumor; Poly(I:C); CpG; Phosphorothioate;
Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release
Keywords: فسفروتیوات; DC; dendritic cell; LN; lymph node; ODN; oligonucleotide; PAMP; pathogen-associated molecular pattern; PAP; prostatic acid phosphatase; PO; phosphodiester; PS; phosphorothioate; PRR; pattern recognition receptor; SVP; synthetic vaccine particle; Tfh; foll
The synthesis of isopropylidene mRNA cap analogs modified with phosphorothioate moiety and their evaluation as promoters of mRNA translation
Keywords: فسفروتیوات; DITWNRYIZSNWCT-GLMBPNHYSA-N; LBPNOROTEVWKCZ-PYSDYTEHSA-K; mRNA cap; Transcription in vitro; Translation efficiency; Phosphorothioate; Nucleotide;
Recognition of CpG oligodeoxynucleotides by human Toll-like receptor 9 and subsequent cytokine induction
Keywords: فسفروتیوات; TLR; Toll-like receptor; hTLR9; human toll-like receptor 9; mTLR9; mouse toll-like receptor 9; CpG; cytosine-phosphate-guanine; ODN; oligodeoxynucleotide; PTO; phosphorothioate; PD; phosphodiester; ECD; extracellular domain; LRR; leucine rich repeat;
Stereocontrolled synthesis of dinucleoside phosphorothioates using a fluorous tag
Keywords: فسفروتیوات; Stereocontrolled synthesis; Phosphorothioate; Fluorous; Oxazaphospholidine
Hybridizing ability and nuclease resistance profile of backbone modified cationic phosphorothioate oligonucleotides
Keywords: فسفروتیوات; Phosphorothioate; Backbone modification; Aminoalkyl moiety; UV melting experiment; Nuclease resistance
Reactivity of 3H-1,2,4-dithiazole-3-thiones and 3H-1,2-dithiole-3-thiones as sulfurizing agents for oligonucleotide synthesis
Keywords: فسفروتیوات; Oligonucleotide synthesis; Phosphorothioate; Sulfurization; Phosphoramidite synthesis;
Increase in CpG DNA-induced inflammatory responses by DNA oxidation in macrophages and mice
Keywords: فسفروتیوات; CpG motif; unmethylated CpG dinucleotide; TLR; Toll-like receptor; LPS; lipopolysaccharide; ROS; reactive oxygen species; RA; rheumatoid arthritis; mtDNA; mitochondrial DNA; nDNA; nuclear DNA; ODN; oligodeoxynucleotide; PO; phosphodiester; PS; phosphoroth
β-1,3-Glucan/antisense oligonucleotide complex stabilized with phosphorothioation and its gene suppression
Keywords: فسفروتیوات; Phosphorothioate; Schizophyllan; Antisense;
Phosphorothioate-based ligase-independent gene cloning (PLICing): An enzyme-free and sequence-independent cloning method
Keywords: فسفروتیوات; Enzyme-free cloning; Sequence-independent cloning; Phosphorothioate; Iodine; Mutant library
Efficient conjugation of oligonucleotides through aromatic oxime formation
Keywords: فسفروتیوات; Conjugation; Chemoselective; Conjugate; Oligonucleotide; Oxime; Phosphorothioate;
Phosphorothioate analogs of m7GTP are enzymatically stable inhibitors of cap-dependent translation
Keywords: فسفروتیوات; 5′ mRNA cap analogs; Phosphorothioate; Inhibition of translation; Translation initiation factor eIF4E; Decapping Scavenger DcpS; Nucleotide synthesis
Geometrical and vibrational features of phosphate, phosphorothioate and phosphorodithioate linkages interacting with hydrated cations: A DFT study
Keywords: فسفروتیوات; Phosphate; Phosphorothioate; Phosphorodithioate; Mono- and divalent counterions; Hydration; Nucleic acids; Ab initio calculations; Density functional theory; Vibrational spectra
A proteomic study reveals unspecific apoptosis induction and reduction of glycolytic enzymes by the phosphorothioate antisense oligonucleotide oblimersen in human melanoma cells
Keywords: فسفروتیوات; Oblimersen; Phosphorothioate; siRNA; Apoptosis; Glycolysis; Proteomics
Synthesis and immunostimulatory properties of the phosphorothioate analogues of cdiGMP
Keywords: فسفروتیوات; cdiGMP; Vaccine adjuvant; Immunostimulation; Phosphorothioate
Combinatorial selection of a single stranded DNA thioaptamer targeting TGF-β1 protein
Keywords: فسفروتیوات; Transforming growth factor-β1; Selection; Aptamer; Phosphorothioate; Thioaptamer; Chemiluminescence; Entropy
Diastereomer characterizations of nitroxide-labeled nucleic acids
Keywords: فسفروتیوات; Site-directed spin labeling; DNA; RNA; Phosphorothioate; Diastereomer;
Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mice
Keywords: فسفروتیوات; CpG DNA; Phosphorothioate; Peritoneal dissemination; Cationic liposome; Macrophage
Combinatorial selection of a RNA thioaptamer that binds to Venezuelan equine encephalitis virus capsid protein
Keywords: فسفروتیوات; Venezuelan equine encephalitis virus; Capsid; Aptamer; Phosphorothioate; Chemiluminescence; Entropy
Thioaptamer Interactions with Prion Proteins: Sequence-specific and Non-specific Binding Sites
Keywords: فسفروتیوات; PK, proteinase K; PrP, prion protein; rec, recombinant; Hu, human; Bo, bovine; SHa, Syrian hamster; AP, alkaline phosphatase; ODN, oligodeoxynucleotideprions; aptamer; phosphorothioate; thioaptamer
Evaluation of synthetic oligonucleotides as inhibitors of West Nile virus replication
Keywords: فسفروتیوات; Conserved RNA sequences; G-quartet; Facilitated uptake; Ribonuclease H; 2â²-O-Methyl-RNA oligonucleotides; Phosphorothioate;
Antisense oligonucleotides: Efficient synthesis of 2′-O-methoxyethyl phosphorothioate oligonucleotides using 4,5-dicyanoimidazole. Are these oligonucleotides comparable to those synthesized using 1H-tetrazole as coupling activator?
Keywords: فسفروتیوات; Oligonucleotide synthesis; Activator; Dicyanoimidazole; Phosphorothioate; Antisense; 1H-Tetrazole
Synthesis of phosphatase-resistant analogues of phytic acid (InsP6)
Keywords: فسفروتیوات; Phytic acid; InsP6; myo-Inositol; Phosphorothioate; Phosphoroselenoate; Methylphosphonate; Phosphatase resistant; Affinity matrix;
High fidelity PCR with an off/on switch mediated by proofreading polymerases combining with phosphorothioate-modified primer
Keywords: فسفروتیوات; Fidelity polymerases; Polymerase chain reaction; Phosphorothioate;