دانلود مقالات ISI درباره Pi3K + ترجمه فارسی

Adenosine A1 receptor stimulation enhances osteogenic differentiation of human dental pulp-derived mesenchymal stem cells via WNT signaling

Keywords: ADA; adenosine deaminase; A1R; adenosine A1 receptors; A2AR; adenosine A2A receptors; A2BR; adenosine A2B receptors; A3R; adenosine A3 receptors; ALP; alkaline phosphatase; ARS; Alizarin Red S staining; CCPA; 2-chloro-N6-cyclopentyladenosine; CGS21680; 2-

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Switching from MAPK-dependent to MAPK-independent repression of the sodium-iodide symporter in 2D and 3D cultured normal thyroid cells

Keywords: EGF; epidermal growth factor; EMT; epithelial to mesenchymal transition; ERK1/2; extracellular-signal regulated kinase 1/2; FBS; fetal bovine serum; IGF-1; insulin-like growth factor-1; LY294002; PI3K inhibitor; MAPK; mitogen-activated protein kinase; MEK

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of a small molecule that induces ATG5-and-cathepsin-l-dependent cell death and modulates polyglutamine toxicity

Keywords: APH; aphidicolin; ATG; Autophagy gene; DKO; double knockout; 3-MA; 3-methyl adenine; HU; Hydroxyurea; MEF; mouse embryo fibroblasts; NID; Novel inducer of death; PI3K; phosphotidyl inositol 3-kinase; RIP-1; Receptor Interacting Protein-1, STS, staurospori

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

The eosinophil chemoattractant 5-oxo-ETE and the OXE receptor

Keywords: 12-HHT; 12-hydroxy-5Z,8E,10E-heptadecatrienoic acid; 5,12-diHETE; 5S,12S-dihydroxy-6E,8Z,10E,14Z-eicosatetraenoic acid; 5,15-diHETE; 5S,15S-dihydroxy-6E,8Z,11Z,13E-eicosatetraenoic acid; 5-HEDH; 5-hydroxyeicosanoid dehydrogenase; 5-HEPE; 5S-hydroxy-6E,8Z,

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Pathogenesis, Diagnosis, and Management of Cholangiocarcinoma

Keywords: Cancer-Associated Fibroblasts; Distal Cholangiocarcinoma; Intrahepatic Cholangiocarcinoma; Molecular Pathogenesis; α-SMA; α-smooth muscle actin; CA19-9; carbohydrate antigen 19-9; CAF; cancer-associated fibroblast; CCA; cholangiocarcinoma; CT; computed

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Gene expression profiling for analysis acquired oxaliplatin resistant factors in human gastric carcinoma TSGH-S3 cells: The role of IL-6 signaling and Nrf2/AKR1C axis identification

Keywords: AKR1Cs; aldo-keto reductase family members (e.g. AKR1C1, AKR1C2, or AKR1C3); ARE; antioxidant response element; cisplatin; cis-diamminedichloroplatinum(II) (CDDP); ERCC-1; excision repair cross-complementing-1; ERK; extracellular signal-related kinase; FF

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Autophagy, polyphenols and healthy ageing

Keywords: AD; Alzheimer's disease; AMP; adenosine monophosphate; AMPK; adenosine monophosphate activated protein kinase; APP; amyloid beta precursor protein; Atg; autophagy (related gene); ATP; adenosine triphosphate; AV; autophagic vacuoles; Aβ; amyloid beta; Bcl

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

BST-2/tetherin is overexpressed in mammary gland and tumor tissues in MMTV-induced mammary cancer

Keywords: BST-2; Bone marrow stromal cell antigen 2; NMuMG; Normal murine mammary gland; FACS; Fluorescence activated cell sorting; PI3K; Phosphoinositide 3 kinase; MIP1-α/CCL3; Macrophage inflammatory protein 1-alpha; BST-2; Tumor; Cancer; Epithelial cells; Mamma

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Complex I impairment in mitochondrial diseases and cancer: Parallel roads leading to different outcomes

Keywords: CI; complex I; CIII; complex III; CIV; complex IV; CV; complex V; DB; decyl-benzoquinone; D-loop; displacement loop; HIF1α; hypoxia inducible factor 1α; LDH; lactate dehydrogenase; LHON; Leber's hereditary optic neuropathy; LS; Leigh syndrome; MELAS; mi

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

E-type prostanoid receptor 4 (EP4) in disease and therapy

Keywords: AMPK; AMP-activated protein kinase; cAMP; cyclic adenylyl monophosphate; CFTR; cystic fibrosis transmembrane conductance regulator; ClC; chloride channel; COX; cyclooxygenase; CREB; cAMP-response element-binding protein; DP; D-type prostanoid receptor; DS

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

Cannabinoid receptor signaling in progenitor/stem cell proliferation and differentiation

Keywords: Cell commitment; Cell survival; Endocannabinoids; Membrane receptors; Niche cues; Protein kinases; Transcription factors; 2-AG; 2-arachidonoylglycerol; AEA; N-arachidonoylethanolamine; BDNF; brain derived neurotrophic factor; CBD; cannabidiol; CBG; cannab

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

B-lymphocyte lineage cells and the respiratory system

Keywords: B cells; plasma cells; plasmablasts; respiratory diseases; AID; Activation-induced cytidine deaminase; APRIL; A proliferation-inducing ligand; BAFF; B cell-activating factor of the TNF family; BAL; Bronchoalveolar lavage; BCMA; B-cell maturation antigen

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2013 سفارش ترجمه

Modulation of the peroxiredoxin system by cytokines in insulin-producing RINm5F cells: Down-regulation of PRDX6 increases susceptibility of beta cells to oxidative stress

Keywords: Akt; v-akt murine thymona viral oncogene homolog 1; IFN-gamma; interferon gamma; IL-1beta; interleukin 1 beta; JNK; c-Jun N-terminal kinase; NF-kappaB; Nuclear factor of kappa light polypeptide gene enhancer in B cells 1; PI3K; phosphatidylinositol 3'ki

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2013 سفارش ترجمه

Recent advances on the beneficial use and health implications of Pu-Erh tea

Keywords: AGE; Advanced glycation end products; AFB1; Aflatoxin B1; ALT; Alanine aminotransferase; ANOVA; Analysis of variance; AST; Aspartate amino-transferase; BMI; Body mass index; BW; Body weight; CCl4; Carbon tetrachloride; CVD; Cardiovascular disease; CHO; Ch

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2013 سفارش ترجمه

Nitric oxide regulates AKT phosphorylation and nuclear translocation in cultured retinal cells

Keywords: AKT; protein kinase B; L-Arg; l-arginine; L-NAME; N-nitro-l-arginine methyl ester; NO; nitric oxide; NMDA; N-methyl-d-aspartate; MK-801; (5R,2S)-(1)5methyl-10,11-dihydro-5H-dibenzo [a,d] cyclohepten-5,10-imine hydrogen maleate; NOS; nitric-oxide synthase;

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2013 سفارش ترجمه

The sources of salidroside and its targeting for multiple chronic diseases

Keywords: 6-OHDA; 6-hydroxydopamine; Aβ; β-amyloid protein; MPTP; 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine; MPP+; N-methyl-4-phenylpyridine; AD; Alzheimer's disease; PD; Parkinson's disease; STZ; streptozotocin; PI3K; phosphatidylinositol 3-kinase; ROS; react

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2020 سفارش ترجمه

Hypoglycemic effect and mechanism of a pectic polysaccharide with hexenuronic acid from the fruits of Ficus pumila L. in C57BL/KsJ db/db mice

Keywords: Akt; protein kinase B; AMPK; AMP-activated protein kinase; DC; diabetic control; DEAE; diethylaminoethyl; DFH; FPLP 200 mg kg−1 day−1 group; DFL; FPLP 100 mg kg−1 day−1 group; DR; 2 kg−1 day−1 rosiglitazone group; FBG; fasting blood gl

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Modulation of mitochondrial apoptosis by PI3K inhibitors

Keywords: Mitochondria; Apoptosis; PI3K

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

PI3K signaling: A key pathway in the control of sympathetic traffic and arterial pressure by leptin

Keywords: Leptin; PI3K; Autonomic nervous system; Cardiovascular function; Energy homeostasis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Impact of targeting insulin-like growth factor signaling in head and neck cancers

Keywords: IGF; insulin-like growth factor; IGF-1-R; insulin-like growth factor-1 receptor; IRS; insulin receptor substrate; IGFBP; insulin-like growth factor binding protein; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; MAPK; mitogen-activa

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Abnormal expression of PI3K isoforms in patients with tobacco-related oral squamous cell carcinoma

Keywords: PI3K; Isoforms; Expression; SPR; IHC; Oral cancer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Tumor necrosis factor–related apoptosis-inducing ligand promotes microvascular endothelial cell hyperpermeability through phosphatidylinositol 3-kinase pathway

Keywords: TRAIL; Vascular permeability; Apoptotic signaling; PI3K

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Biology and therapeutic potential of PI3K signaling in ER+/HER2-negative breast cancer

Keywords: Breast cancer; PI3K; Estrogen receptor; Crosstalk; PIK3CA mutation; Feedback loop

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Signaling pathways mediating the effects of insulin-like growth factor-I in bovine muscle satellite cells

Keywords: Muscle; IGF-I; PI3K; ERK; p70S6K

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

PI3K/Akt/mTOR pathway inhibitors in the therapy of pancreatic neuroendocrine tumors

Keywords: Neuroendocrine tumors; Pancreatic; PI3K; Akt; mTOR; Inhibitor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of angiogenesis by PI3K signaling networks

Keywords: PI3K; AKT; FOXOs; Endothelial cells; Angiogenesis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Both PI3K/Akt and ERK1/2 pathways participate in the protection by dexmedetomidine against transient focal cerebral ischemia/reperfusion injury in rats

Keywords: MCAO; Dexmedetomidine; PI3K; ERK1/2; GSK-3β

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Single prolonged stress enhances hippocampal glucocorticoid receptor and phosphorylated protein kinase B levels

Keywords: PTSD; posttraumatic stress disorder; SPS; single prolonged stress; EPM; elevated plus maze; OF; open field; GR; glucocorticoid receptor; Akt; protein kinase B; pAkt; phosphorylated Akt; PI3K; phosphoinositide 3-kinase; mTOR; mammalian target of Rapamycin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Cell survival and metastasis regulation by Akt signaling in colorectal cancer

Keywords: Akt isoforms; PI3K; Colorectal cancer; Metastasis; Cell survival; TGFβ/PKA signaling

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

A novel imidazopyridine derivative, HS-106, induces apoptosis of breast cancer cells and represses angiogenesis by targeting the PI3K/mTOR pathway

Keywords: PI3K; mTOR; Apoptosis; Angiogenesis; Breast cancer

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

IPD-196, a novel phosphatidylinositol 3-kinase inhibitor with potent anticancer activity against hepatocellular carcinoma

Keywords: PI3K; Anticancer; Apoptosis; Angiogenesis; HCC

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Synthetic lethal interaction between PI3K/Akt/mTOR and Ras/MEK/ERK pathway inhibition in rhabdomyosarcoma

Keywords: Apoptosis; Rhabdomyosarcoma; PI3K; MAPK

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Promise of rapalogues versus mTOR kinase inhibitors in subset specific breast cancer: Old targets new hope

Keywords: Breast cancer; mTOR kinase inhibitor; PI3K; HER2; ER+; Triple negative/basal type

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Study on TRPV1-mediated mechanism for the hypersecretion of mucus in respiratory inflammation

Keywords: TRPV1; Capsaicin; HNE; EGFR; PI3K; PKC; HIF-1α; MUC5AC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

DJ-1 regulates mast cell activation and IgE-mediated allergic responses

Keywords: DJ-1; reactive oxygen species; mast cells; allergy; FcεRI-mediated signals; AD; Atopic dermatitis; BMMC; Bone marrow-derived mast cell; DNP; 2,4-Dinitrophenyl; H2O2; Hydrogen peroxide; KO; Knockout; LAT; Linker for activation of T cells; MAP; Mitogen-a

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Endothelial E-type prostanoid 4 receptors promote barrier function and inhibit neutrophil trafficking

Keywords: Chronic obstructive pulmonary disease; acute lung injury; endothelial barrier; prostaglandins; vascular leakage; neutrophil trafficking; cAMP; Cyclic adenosine monophosphate; ECIS; Electric Cell-substrate Impedance Sensing system; EP; E-type prostanoid; F

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Akt and mTORC1 Have Different Roles During Liver Tumorigenesis in Mice

Keywords: Liver Cancer; Mouse Model; Signal Transduction; Gene Disruption; Akt; v-akt murine thymoma viral oncogene homolog 1; Alb; albumin; DKO; double knock-out; DMEM; Dulbecco's modified Eagle medium; EGF; epidermal growth factor; FBS; fetal bovine serum; FGFR1;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer

Keywords: Isoliquiritigenin; Apoptosis; Eicosanoids; PI3k; Akt; Breast cancer

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of Molecular Subtypes of Gastric Cancer With Different Responses to PI3-Kinase Inhibitors and 5-Fluorouracil

Keywords: Stomach Cancer; GC-Class; Personalized Cancer Treatment; Cancer Classification; PI3K

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

17p Deletion in Chronic Lymphocytic Leukemia

Keywords: CLL; 17p deletion; High-risk; Targeted therapy; BTK; PI3K; BH3 mimetic;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins

Keywords: Head and neck cancer; Xenografts; Human papillomavirus; EGFR; PI3K; NOTCH1

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Functional Toll-like receptor 4 expressed in lactotrophs mediates LPS-induced proliferation in experimental pituitary hyperplasia

Keywords: Lactotroph cells; Toll-like receptor 4; Lipopolysaccharide; PI3K; NF-κB; IL-6; 17β-estradiol

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Progastrin-Induced Secretion of Insulin-Like Growth Factor 2 From Colonic Myofibroblasts Stimulates Colonic Epithelial Proliferation in Mice

Keywords: Mouse Model; Colon Cancer; PKC; PI3K; CCK-2R; cholecystokinin-2 receptor; CgA; chromogranin A; DAPI; 4′,6-diamidino-2-phenylindole; DMSO; dimethyl sulfoxide; FCS; fetal calf serum; G-Gly; glycine-extended gastrin; G-17; gastrin-17; hGAS; high circulatin

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Flavopiridol Synergizes with Sorafenib to Induce Cytotoxicity and Potentiate Antitumorigenic Activity in EGFR/HER-2 and Mutant RAS/RAF Breast Cancer Model Systems

Keywords: BC; breast cancer; CDKs; cyclin-dependent kinases; CI; combination index; EGFR; epidermal growth factor receptor; FFPE; formalin fixed and paraffin embedded; FISH; fluorescence in situ hybridization; FPD; flavopiridol; HER-2; ErbB2/epidermal growth factor

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

MicroRNA-137, an HMGA1 Target, Suppresses Colorectal Cancer Cell Invasion and Metastasis in Mice by Directly Targeting FMNL2

Keywords: Mouse Model; Gene Expression; Tumor Suppressor Activity; Signaling Pathway; Akt; protein kinase B; CRC; colorectal cancer; ERK; extracellular signal-regulated kinase; FMNL2; formin-like 2; HMGA; high-mobility group AT-hook; MAPK; mitogen-activated prote

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

African swine fever virus-cell interactions: From virus entry to cell survival

Keywords: African swine fever virus; ASFV; Virus entry; Endocytosis; Clathrin; Dynamin; Macropinocytosis; Early endosome; Late endosome; Rab GTPases; PI3K; PIKfyve; ER stress; Unfolded protein response; Caspases; Apoptosis; Bcl2; PP1; eIF2α; HDAC6; Autophagy; Becli

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

SPOCK1 Is Regulated by CHD1L and Blocks Apoptosis and Promotes HCC Cell Invasiveness and Metastasis in Mice

Keywords: Liver Cancer; Tumor Progression; Gene Regulation; Signal Transduction; AJCC; American Joint Committee on Cancer; BAD; BCL2-associated agonist of cell death; bp; base pair; cDNA; complementary DNA; CHD1L; chromodomain helicase/adenosine triphosphatase DNA

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

β-Arrestin signal complex plays a critical role in adipose differentiation

Keywords: GHSR1a; growth hormone secretagogue receptor type 1a; PPARγ; peroxisome proliferator-activated receptor; C/EBPα; CCAAT/enhancer-binding protein α; C/EBPβ; CCAAT/enhancer-binding protein β; C/EBPδ; CCAAT/enhancer-binding protein δ; PI3K; phosphatidy

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2013 سفارش ترجمه

Targeting autophagy as a potential therapeutic approach for melanoma therapy

Keywords: 5-ALA; 5-aminolevulinic acid; AMBRA1; autophagy/Beclin 1 regulator 1; APC; antigen-presenting cell; ASS; argininosuccinate synthetase; ATG; autophagy-related; ATM; Ataxia telangiectasia mutated; BafA1; bafilomycin A1; Bif-1; endophilin B1; BN; benign nevi

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2013 سفارش ترجمه

Two distinct mechanisms by which phospholipase C-γ1 mediates epidermal growth factor-induced keratinocyte migration and proliferation

Keywords: EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; Cai; intracellular calcium; NHK; normal human keratinocytes; PLC; phospholipase C; PLC-β1; phospholipase C-β1; PLC-γ1; phospholipase C-γ1; PLC-δ1; phospholipase C-δ1; PI3K; phosph

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه