Thrombin-sensitive expression of the store operated Ca2+ channel Orai1 in platelets
Keywords: Platelet activation; SOCE; Orai1; Thrombin; PI3K; Translation; Pre-mRNA;
مقالات ISI (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
CKIP-1: A scaffold protein and potential therapeutic target integrating multiple signaling pathways and physiological functions
Keywords: ATM; ataxia-telangiectasia mutated; CHX; cycloheximide; CK2; casein kinase 2; CKIP-1; casein kinase 2 interacting protein-1; CP; capping protein; IFN; interferon; IFP35; IFN-induced protein 35kDa; LZ; leucine zipper; Nmi; N-Myc interacting protein; PH; pl
Vasopressin activates Akt/mTOR pathway in smooth muscle cells cultured in high glucose concentration
Keywords: AVP; arginine vasopressin; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; PI3K; phosphatidyl inositol-3 kinase; AMPK; AMP-activated protein kinase; PKC; protein kinase C, Akt or protein kinase B; TSC1/TSC2; tubero sclerosis protein 1 and 2;
Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities
Keywords: PI3K; by phosphatidyl 3-kinase; PI4K; phosphatidyl 4-kinase; PI5K; phosphatidyl 5-kinase; INPP4B; inositol polyphosphate 4-phosphatase type II; PTP; protein tyrosine phosphatase; pNPP; para-nitrophenyl phosphate; DifMUP; 6,8-difluoro-4-methylumbelliferyl
INPP4B-mediated tumor resistance is associated with modulation of glucose metabolism via hexokinase 2 regulation in laryngeal cancer cells
Keywords: ERK-1/2; extracellular signal-regulated protein kinase-1/2; FDG; fluorodeoxyglucose; HIF-1α; hypoxia-inducible factor-1α; HK2; hexokinase 2; INPP4B; inositol polyphosphate 4-phosphatase Type II; PI3K; phosphoinositide 3-kinases; PTEN; phosphatase and te
Reactivation of AKT signaling following treatment of cancer cells with PI3K inhibitors attenuates their antitumor effects
Keywords: PI3K; phosphatidylinositol-3-kinase; PTEN; phosphatase and tensin homolog; PI3K inhibitors; AKT; Cancer; Resistance; Signaling;
Adenosine A2A receptor-dependent proliferation of pulmonary endothelial cells is mediated through calcium mobilization, PI3-kinase and ERK1/2 pathways
Keywords: Adenosine; A2A receptor; Microvascular endothelial cells; Pulmonary; Intracellular calcium; PI3K; ERK1/2;
Differential anti-tumor activities of curcumin against Ras- and Src-activated human adenocarcinoma cells
Keywords: 4E-BP1; eukaryotic initiation factor 4-binding protein 1; Cdk1; cyclin-dependent kinase 1; EGFR; epidermal growth factor receptor; FACS; fluorescence activated cell sorting; IC50; 50% inhibitory concentration; MAPK; mitogen-activated protein kinase; mTOR;
Insulin suppression of apolipoprotein B in McArdle RH7777 cells involves increased sortilin 1 interaction and lysosomal targeting
Keywords: Apo B; apolipoprotein B; B100; apo B derived from unedited mRNA; VLDL; very low density lipoprotein; PI3K; phosphatidylinositide 3-kinase; ERAD; endoplasmic reticulum associated degradation; PERPP; post ER presecretory proteolysis; BafA1; Bafilomycin A1;
Insulin receptor substrate-1 (IRS-1) forms a ribonucleoprotein complex associated with polysomes
Keywords: IRSs; insulin receptor substrates; IGFs; insulin-like growth factors; PABPC1; poly(A) binding protein cytoplasmic 1; MALDI-TOF-MS; matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry; BN-PAGE; blue native-polyacrylamide gel elec
Immobilized amyloid Aβ peptides support platelet adhesion and activation
Keywords: AD; Alzheimer disease; PLC; phospholipase C; PI3K; phosphatidylinositol 3 kinase; APP; amyloid precursor protein; PKC; protein kinase C; Amyloid Aβ peptide; Human platelet; Adhesion; Cerebrovascular inflammation;
Inhibiting the phosphatidylinositide 3-kinase pathway blocks radiation-induced metastasis associated with Rho-GTPase and Hypoxia-inducible factor-1 activity
Keywords: Radiotherapy; Metastasis; PI3K; HIF-1; Rho-GTPases; GDC-0941;
Jurkat cell proliferation is suppressed by Chlamydia (Chlamydophila) pneumoniae infection accompanied with attenuation of phosphorylation at Thr389 of host cellular p70S6K
Keywords: PBMC; peripheral blood mononuclear cell; FCS; fetal calf serum; FITC; fluorescein isothiocyanate; LPS; lipopolysaccharide; HBSS; Hank's balanced salt solution; PI3K; mammalian target of rapamycin; mTOR; phosphoinositide 3-kinase; mTORC1; multi-component m
NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway
Keywords: AKT; v-akt murine thymoma viral oncogene; CRC; colorectal cancer; FDR; false discovery rate; HECT; homologous to E6AP C terminus; KEGG; Kyoto Encyclopedia of Genes and Genomes; mut; mutated; NCBI; National Center for Biotechnology Information; PBS; phosph
Lancemaside A inhibits microglial activation via modulation of JNK signaling pathway
Keywords: AP-1; activator protein-1; COX-2; cyclooxygenase-2; ERK; extracellular signal-regulated kinase; HO-1; hemeoxygenase-1; iNOS; inducible nitric oxide synthase; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; NF-κB; nuclear factor-κB;
Comparison of influenza virus yields and apoptosis-induction in an adherent and a suspension MDCK cell line
Keywords: 1:2dil; 1:2 dilution at toi; A/PR/8; A/Puerto Rico/8/34; CEACAM6; carcinoembryonic antigen-related cell adhesion molecule 6; EMA; European medicines agency; FDA; Food and Drug Administration; FITC; fluorescein isothiocyanate; GMEM; Glasgow minimum essenti
PI3K is required for the physical interaction and functional inhibition of NF-κB by β-catenin in colorectal cancer cells
Keywords: β-Catenin; NF-κB; PI3K; Colorectal cancer;
Feedforward and feedback regulation of the MAPK and PI3K oscillatory circuit in breast cancer
Keywords: HER2; Breast cancer; Oscillation; MAPK; PI3K; Systems biology;
Differential regulation of chemotaxis: Role of Gβγ in chemokine receptor-induced cell migration
Keywords: CHO; Chinese hamster ovary; CCL3; Chemokine ligand 3; CCR5; Chemokine receptor 5; DMEM; Dulbecco's modified Eagle's medium; EDTA; Ethylenediaminetetraacetic acid; ERK; Extracellular signal-regulated kinases; FCS; Foetal calf serum; GPCR; G protein coupled
Hypoxia reduces endothelial Ang1-induced Tie2 activity in a Tie1-dependent manner
Keywords: Ang1; angiopoietin-1; DFX; desferrioxamine; HIF; hypoxia-inducible factor; HUVEC; human umbilical vein endothelial cell; mTOR; mammalian target of rapamycin; PI3K; phosphatidylinositol 3-kinase; VEGF; vascular endothelial growth factor; VE-PTP; vascular e
Relevance of signaling molecules for apoptosis induction on influenza A virus replication
Keywords: Akt; v-akt murine thymoma viral oncogene homolog 1; Apaf-1; apoptotic protease activating factor 1; Bax; Bcl-2-associated x protein; Bcl-2; B-cell lymphoma 2; BH; Bcl-2 homology; Caspases; cysteine-aspartic acid protease; DAP3; death-associated protein
Regulatory mechanisms for glycogenolysis and K+ uptake in brain astrocytes
Keywords: AE; anion exchanger; AMPK; AMP-activated protein kinase; CA; carbonic anhydrase; CTS; cardiotonic steroids; DAB; 1,4-dideoxy-1,4-imino-d-arabinitol; DIDS; 4,4â²-diisothiocyanostilbene-2,2â²-disulfonic acid; EGFR; epidermal growth factor receptor; ERK; e
Inhibitory effects of p-dodecylaminophenol on the invasiveness of human fibrosarcoma cell line HT1080
Keywords: 1; p-dodecylaminophenol, 4-(dodecylamino)phenol; 2; N-(4-hydroxyphenyl)retinamide, fenretinide; 3; all-trans-retinoic acid; DMSO; dimethylsulfoxide; BSA; bovine serum albumin; PBS; phosphate-buffered saline (1.5Â mM KH2PO4, 8.1Â mM Na2HPO4, 136.9Â mM NaCl
miR-21 confers cisplatin resistance in gastric cancer cells by regulating PTEN
Keywords: miRNAs; microRNAs; miR-21; microRNA-21; DDP; cisplatin; PTEN; phosphatase and tension homolog deleted on chromosome 10; MTT; the thiazolyl blue tetrazolium blue; PI; propidium iodide; 3â²UTR; 3â²untranslated region; NC; negative control; IC50; the 50% i
IL-10 modulates serotonin transporter activity and molecular expression in intestinal epithelial cells
Keywords: GI; gastrointestinal; 5-HT; 5-hydroxytryptamine, serotonin; SERT; serotonin transporter; IBS; Irritable Bowel Syndrome; IBD; Inflammatory Bowel Diseases; IL-10; Interleukin-10; IL-10R; Interleukin-10 receptor; IL10RA; Interleukin-10 receptor subunit alpha
Dehydration mediated microRNA response in the African clawed frog Xenopus laevis
Keywords: AMPK; Adenosine monophosphate-activated protein kinase; ERK; Extracellular signal-regulated kinases; HIF-1α; Hypoxia inducible factor-1α; JNK; C-Jun N-terminal kinases; KEGG; Kyoto encyclopedia of Genes and Genomes; MAPK; Mitogen activated protein kinas
HIV-1 gp120 induces autophagy in cardiomyocytes via the NMDA receptor
Keywords: Autophagy; HIV-1 gp120; NMDA receptor; Cardiomyocyte; PI3K; JNK;
Research ArticleAdiponectin and resistin protect steatotic livers undergoing transplantation
Keywords: I/R; ischemia-reperfusion; PC; ischemic preconditioning; Ob; obese; Ln; lean; TR; transplantation; UW; University of Wisconsin; AMPK; AMP-activated protein kinase; AICAR; aminoimidazole-4-carboxamide ribonucleoside; PI3K; phosphoinositide-3-kinase; ALT; a
Kinin-B2 receptor exerted neuroprotection after diisopropylfluorophosphate-induced neuronal damage
Keywords: 2-PAM; pralidoxime; AChE; acetylcholinesterase; ACSF; artificial cerebrospinal fluid; B1BKR; kinin-B1 receptor; B2BKR; kinin-B2 receptor; BK; bradykinin; DFP; diisopropylfluorophosphate; MEK/MAPK; mitogen-activated protein kinase; NMDA; N-methyl-d-asparta
Selaginella tamariscina (Beauv.) possesses antimetastatic effects on human osteosarcoma cells by decreasing MMP-2 and MMP-9 secretions via p38 and Akt signaling pathways
Keywords: Metastasis; Selaginella tamariscina; Osteosarcoma; MMP-2; MMP-9; ECM; extracellular matrix; ERK; extracellular signal-regulated protein kinase; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; MMP; matrix metalloproteinase; PI3K; phos
Transient knockdown of presenilin-1 provokes endoplasmic reticulum stress related formation of autophagosomes in HepG2 cells
Keywords: Presenilin; Endoplasmic reticulum; Autophagy; ER stress; PI3K; Calcium;
Cholesterol induces cardiac hypertrophy by activating the AKT pathway
Keywords: IGF; insulin growth factor; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; PI3K; phosphatidylinositol-3-kinase; GPCR; G-protein-coupled receptor; mTOR; mammalian target of rapamycin; GSK3β; phospho-glycogen synthase k
Jaceosidin, isolated from dietary mugwort (Artemisia princeps), induces G2/M cell cycle arrest by inactivating cdc25C-cdc2 via ATM-Chk1/2 activation
Keywords: ATM; atazia-telagiectasia mutated; Caspase; cystein aspartyl-specific protease; Cdc 2; cell division cycle 2; Cdk; cyclin-dependent kinase; CDKI; cyclin-dependent kinase inhibitor; ERK; extracellular signal-regulated kinase; MAPK; mitogen activated protei
Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence
Keywords: OIS; oncogene-induced senescence; MEF; mouse embryonic fibroblast; ERK; extracellular signal-regulated kinase; MEK; mitogen-activated protein kinase kinase; PI3K; phosphatidylinositol 3-kinase; pRb; retinoblastoma tumor suppressor protein; SA-β-Gal; sene
Ionizing-radiation induced DNA double-strand breaks: A direct and indirect lighting up
Keywords: bp; base-pair; DDR; DNA damage response; DNA-PKcs; catalytic subunit of the DNA-dependent protein kinase; DSB; DNA Double-Strand Break; HR; homologous recombination; IR; ionizing radiation; IRIF; ionizing radiation induced foci; LET; Linear Energy Transfe
Glycyrrhizic acid and 18β-glycyrrhetinic acid recover glucocorticoid resistance via PI3K-induced AP1, CRE and NFAT activation
Keywords: Glycyrrhizic acid; 18β-Glycyrrhetinic acid; Glucocorticoid receptor; Phosphoinositide 3-kinase; Glucocorticoid resistance; 18βGA; 18β-glycyrrhetinic acid; Akt; protein kinase B; AP1; activator protein 1; COPD; chronic obstructive pulmonary disease; CRE
Reversal of dexamethasone induced insulin resistance in 3T3L1 adipocytes by 3β-taraxerol of Mangifera indica
Keywords: DEX; dexamethasone; DMEM; Dulbecco's modified Eagle's medium; ELISA; enzyme linked immunosorbent assay; FCS; fetal calf serum; GLUT 4; glucose transporter 4; GS; glycogen synthase; GSK3β; glycogen synthase kinase beta; IR β; insulin receptor beta; IRS1;
HER2 regulates Brk/PTK6 stability via upregulating calpastatin, an inhibitor of calpain
Keywords: ALLN; N-acetyl-leucyl-leucyl-norleucinal; Brk; breast tumor kinase; CHX; cycloheximide; DMEM; Dulbecco's modified Eagle's medium; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; Erk; extracellular signal-regulated kinase; FAK;
New advances of DNA methylation in liver fibrosis, with special emphasis on the crosstalk between microRNAs and DNA methylation machinery
Keywords: miRNAs; small non-coding RNAs; HSC; hepatic stellate cell; ECM; extracellular matrix; α-SMA; α-smooth muscle actin; TGF-β; transforming growth factor-β; PDGF; platelet-derived growth factor; FGF; fibroblast growth factor; ICAM-1; intercellular adhesio
Rapid activation of FAK/mTOR/p70S6K/PAK1-signaling controls the early testosterone-induced actin reorganization in colon cancer cells
Keywords: DEX; Dexamethasone; FAK; Focal Adhesion Kinase; HSA; human serum albumin; iAR; intracellular androgen receptor; mTOR; mammalian target of rapamycin; mAR; membrane androgen receptor; PAK1; p21-activated kinase 1; p70S6K; S6 kinase; PFA; paraformaldehyde; P
Production of Cyr61 protein is modulated by extracellular acidification and PI3K/Akt signaling in prostate carcinoma PC-3 cells
Keywords: NAC; N-acetylcysteine; ECM; extracellular matrix; PI3K; phosphoinositide 3-kinase; SDS; sodium dodecyl sulfate; HRP; horseradish peroxidase; ECL; enhanced chemiluminescence; siRNA; small interfering RNA; PBS; phosphate buffered saline; Akt; serine/threoni
BIG1, a brefeldin A-inhibited guanine nucleotide-exchange protein regulates neurite development via PI3K-AKT and ERK signaling pathways
Keywords: AKT; protein kinase B; Arf; ADP-ribosylation factor; BFA; brefeldin A; BIG1; BFA-inhibited guanine nucleotide-exchange protein 1; DIV; days in vitro; ECL; Dulbecco's modification of Eagle's medium; ER; enhanced chemiluminescence; EDTA; ethylenediamine
LRIG1 dictates the chemo-sensitivity of temozolomide (TMZ) in U251 glioblastoma cells via down-regulation of EGFR/topoisomerase-2/Bcl-2
Keywords: EGFR; Epidermal growth factor receptor; GBM; glioblastoma multiforme; RNAi RNA interference; LRIG1; , leucine-rich repeats and immunoglobulin-like domains 1; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; TMZ; temozolomide; Topo
Effect of treadmill exercise on the BDNF-mediated pathway in the hippocampus of stressed rats
Keywords: Treadmill exercise; Immobilization stress; BDNF; PI3K; MTOR; Synaptic proteins; BDNF; Brain-derived neurotrophic factor; PI3K; Phosphatidylinositol 3-kinase; GSK-3β; Glycogen synthase kinase-3β; mTOR; mammalian target of rapamycin; p70S6K; p70 ribosomal
Therapeutic concentrations of valproate but not amitriptyline increase neuropeptide Y (NPY) expression in the human SH-SY5Y neuroblastoma cell line
Keywords: AMI; amitriptyline; AP-1; activator protein 1; Atoh1; atonal homolog-1; BDNF; brain-derived neurotrophic factor; bp; base pair; CREB; cAMP response element-binding protein; Cp; crossing point; ERK; extracellular signal-regulated kinase; DMEM/F12 Ham; Dulb
Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K-Akt signaling pathways
Keywords: ANP; atrial natriuretic peptide; BATF; B-cell activating transcription factor; FKHR(Foxo1a); forkhead in human rhabdomyosarcoma; NPRA; natriuretic peptide receptor A; PI3K; phosphatidylinositol 3â²-kinase; PKG; cGMP-dependent protein kinase; ROR; retinoi
Gui-ling-gao (turtle jelly), a traditional Chinese functional food, exerts anti-inflammatory effects by inhibiting iNOS and pro-inflammatory cytokine expressions in splenocytes isolated from BALB/c mice
Keywords: ACD; acid citrate-dextrose; ERK-1/2; extracellular signal-regulated kinases 1 and 2; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GLG; Gui-ling-gao; HPLC; high performance liquid chromatography; IL-1β; interleukin-1β; iNOS; inducible nitric oxide sy
XJP-1 protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by inhibiting NADPH oxidase subunit expression and modulating the PI3K/Akt/eNOS pathway
Keywords: XJP-1; Ox-LDL; Endothelial apoptosis; NADPH oxidase; PI3K;
In vitro and in vivo anti-inflammatory effect of Rhodomyrtus tomentosa methanol extract
Keywords: PG; prostaglandin; NO; nitric oxide; COX; cyclooxygenase; iNOS; inducible NO synthase; (TNF)-α; tumour necrosis factor; ERK; extracellular signal-related kinase; TLR; Toll-like receptors (TLR); MAPK; mitogen activated protein kinase; NF-κB; nuclear fact
Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages
Keywords: Arctigenin; Inflammation; Macrophages; PI3K; Polarization;