دانلود مقالات ISI درباره Pkr + ترجمه فارسی

p-Coumaric acid inhibits indoleamine 2, 3-dioxygenase expression in murine dendritic cells

Keywords: DC, dendritic cells; IDO, Indoleamine 2, 3-dioxygenase; CA, p-Coumaric acid; STAT, Activation of the signal transducer and activator of transcription; PRL, prolactin; IFN-γ, Interferon-γ.IDO; Murine BMDCs; IFN-γ; STAT1; PKR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Induction of homotypic aggregation in the rainbow trout macrophage-like cell line, RTS11

Keywords: Homotypic aggregation; Monocyte/macrophage; RTS11; dsRNA; Integrin; Galectin; PKR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Viral dsRNA Inhibitors Prevent Self-association and Autophosphorylation of PKR

Keywords: PKR, protein kinase RNA; PKRP, phosphorylated PKR; ITC, isothermal titration calorimetry; dsRBD, dsRNA binding domain; DLS, dynamic light scatteringRNA; PKR; kinase; inhibition; virus

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Translational Inhibition of Colonic Epithelial Heat Shock Proteins by IFN-γ and TNF-α in Intestinal Inflammation

Keywords: eIF-2α; eukaryotic initiation factor-2α; iHsp; inducible heat shock proteins; IL; interleukin; PAPR; poly-ADP ribose polymerase; PCR; polymerase chain reaction; PKR; RNA-dependent protein kinase; PKR-I; PKR inhibitor; TNF-α; tumor necrosis factor α; Y

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

The dsRNA protein kinase PKR: Virus and cell control

Keywords: Protein kinase; PKR; dsRNA-dependent enzyme; Antiviral; Anticellular; Translational control; Signal transduction; Modulation; Apoptosis

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

PKR: A NMR perspective

Keywords: NMR; PKR; eIF2α; Mechanism; Structure;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2007 سفارش ترجمه

Inhibition of hepatitis C virus RNA replication by short hairpin RNA synthesized by T7 RNA polymerase in hepatitis C virus subgenomic replicons

Keywords: Hepatitis C virus; RNAi; Synthesized shRNA; T7 RNA polymerase; IFN; PKR; 2′-5′OAS; Hepatitis C virus subgenomic replicons

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Modulation of PKR activity in cells infected by bovine viral diarrhea virus

Keywords: Bovine viral diarrhea virus; Persistent infection; Innate immunity; Double stranded RNA-dependent protein kinase; PKR; NF-κB

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA

Keywords: PKR; Influenza virus; Double-stranded RNA; PACT; Viral evasion; Interferon action

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Role of epithelial nitric oxide in airway viral infection

Keywords: BALF; bronchoalveolar lavage fluid; CF; cystic fibrosis; cGMP; guanosine 3′,5′-cyclic monophosphate; CMV; cytomegalovirus; dsRNA; double-stranded RNA; EPO; eosinophil peroxidase; GAS; γ-activated site; GSH; reduced glutathione; HIV; human immunodefic

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Ebp1 is a dsRNA-binding protein associated with ribosomes that modulates eIF2α phosphorylation

Keywords: Ebp1; dsRNA; Ribosome; eIF2α; PKR; Protein translation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Integrin alpha 11 is a novel type I interferon stimulated gene

Keywords: Integrin alpha 11; Interferons α/β; PKR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Receptors and ligands involved in viral induction of type I interferon production by plasmacytoid dendritic cells

Keywords: Plasmacytoid dendritic cells; Type I interferon; Viral glycoprotein; DCs; dendritic cells; dsRNA; double-stranded RNA; HA; haemagglutinin; HCMV; human cytomegalovirus; HCV; hepatitis C virus; HEK; human embryonic kidney cells; HIV; human immunodeficiency

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Inhibition of PKR by RNA and DNA viruses

Keywords: PKR; Interferon; Interferon-resistance; RNA viruses; DNA viruses; Innate immune evasion

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

The N-terminus of PKR is responsible for the activation of the NF-κB signaling pathway by interacting with the IKK complex

Keywords: PKR; NF-κB; IKK; dsRNA; TLR; Innate immunity

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

A Conserved Dimer and Global Conformational Changes in the Structure of apo-PknE Ser/Thr Protein Kinase from Mycobacterium tuberculosis

Keywords: STPK, Ser/Thr protein kinase; Mtb, Mycobacterium tuberculosis; KD, kinase domain; SAD, single wavelength anomalous diffractionkinase activation; allosteric regulation; bacterial phosphosignaling; PKR; DFG motif

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Double-stranded RNA-dependent protein kinase (PKR) is a stress-responsive kinase that induces NFκB-mediated resistance against mercury cytotoxicity

Keywords: PKR; Mercury toxicity; Type I interferons; Cellular stress; ROS; Resistance

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Functional characterisation of the Japanese flounder, Paralichthys olivaceus, Mx promoter

Keywords: Japanese flounder; Mx promoter; Interferon; ISRE; PKR;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Specific Recognition of HIV TAR RNA by the dsRNA Binding Domains (dsRBD1–dsRBD2) of PKR

Keywords: PKR; dsRBD; TAR RNA; NMR; specific recognitionPKR, double-stranded RNA-dependent protein kinase; dsRNA, double-stranded RNA; TAR, tat activation response region; RBD, RNA binding domain; ITC, isothermal titration calorimetry; TROSY, transverse relaxation

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Uncoupling of RNA Binding and PKR Kinase Activation by Viral Inhibitor RNAs

Keywords: RNA; PKR; kinase; inhibitionPKR, protein kinase RNA-activated; dsRNA, double-stranded RNA; eIF2α, eukaryotic initiation factor 2α; dsRBD, double-stranded RNA-binding domain; ITC, isothermal titration calorimetry; NOESY, nuclear Overhauser effect spectrosc

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه

The interferon system of teleost fish

Keywords: Interferons; Interferon alpha; Interferon gamma; Antiviral; Interferon receptor; JAK–STAT; Mx protein; PKR; ISG15; ISG56; Phylogeny; Evolution; Fish

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2006 سفارش ترجمه

Interaction of recombinant human eIF2 subunits with eIF2B and eIF2α kinases

Keywords: Translational initiation; eIF2α, β, γ; eIF2B; PERK; PKR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Dichotomy between survival and lytic gene expression in RNase L- and PKR-deficient mice transduced with an adenoviral vector expressing murine IFN-β following ocular HSV-1 infection

Keywords: HSV-1; keratitis; adenoviral vector; IFN-β; OAS; PKR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Double-strand RNA dependent protein kinase (PKR) is involved in the extrastriatal degeneration in Parkinson's disease and Huntington's disease

Keywords: AD; Alzheimer's disease; ER; endoplasmic reticulum; HD; Huntington's disease; PD; Parkinson's disease; PKR; double-strand RNA dependent protein kinase; p-PKR; phosphorylated PKR; SDS-PAGE; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; PKR; ER

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Antiviral effects of sophoridine against coxsackievirus B3 and its pharmacokinetics in rats

Keywords: BW; body weight; HW; heart weight; CVB3; Coxsackievirus B3; DCM; dilated cardiomyopathy; IFN; interferon; IL; interleukin; TNF; tumor necrosis factor; NF-κB; nuclear factor kappa B; RT-PCR; reverse transcriptase polymerase chain reaction; PKR; dsRNA activ

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Interferon-Stimulated Gene Expression in Black and White Hepatitis C Patients During Peginterferon Alfa-2a Combination Therapy

Keywords: ADAR1; adenosine deaminase-1; ETR; end-of-treatment virologic response or responder; EVNR; early virologic nonresponder; EVR; early virologic response or responder; IFN alfa; interferon alfa; ISG; interferon-stimulated gene(s); MxA; myxovirus resistance-A

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Double-stranded RNA-dependent protein kinase is required for bone calcification in MC3T3-E1 cells in vitro

Keywords: Bone; Osteoblasts; PKR; Runx2; STAT1α;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Dying a Thousand Deaths: Redundant Pathways From Different Organelles to Apoptosis and Necrosis

Keywords: Akt; proto-oncogene product of the viral oncogene v-akt; AIF; apoptosis inducing factor; Apaf-1; apoptotic protease activating factor-1; ATF6; activating transcription factor 6; Bad; heterodimeric partner for Bcl-xL and Bcl-2; Bak; Bcl2 homologous antagon

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Enhancement of apoptosis via an extrinsic factor, TNF-α, in cells infected with cytopathic bovine viral diarrhea virus

Keywords: Bovine viral diarrhea virus; Apoptosis; Tumor necrosis factor; Inducible nitric oxide synthase; Mucosal disease; BFM; bovine fetal muscle; BVDV; bovine viral diarrhea virus; CP; cytopathic; CPE; cytopathic effect; DMEM; Dulbecco's modified Eagle's medium;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Interferons (IFNs) are key cytokines in both innate and adaptive antiviral immune responses-and viruses counteract IFN action

Keywords: Interferons; Innate antiviral immunity; Interferon-regulatory factor; Toll-like receptors; AP-1; activating protein 1; CARD; caspase recruitment domain; CpG DNA; unmethylated double-stranded DNA; DC; dendritic cell; dsRNA; double-stranded RNA; GAS; IFN ga

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Immunoglobulin mimicry by Hepatitis C Virus envelope protein E2

Keywords: aa; amino acid(s); BLAST; basic local alignment search tool; CDR; complementarity determining region; E2; envelope protein 2; eIF2α; eukaryotic initiation factor 2α; FR; framework region; HCV; hepatitis C virus; Ig; immunoglobulin; HVR1; hypervariable r

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Signal transduction pathways leading to increased eIF4E phosphorylation caused by oxidative stress

Keywords: BSO; buthionine sulfoximine; DMEM; Dulbecco's modified essential medium; EBSS; Earle's Balanced Salts Solution; EGF; epidermal growth factor; eIF; eukaryotic initiation factor; eIF4E-BP; eIF4E-binding protein; FBS; fetal bovine serum; GCS; glutathione cys

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Cellular abnormalities linked to endoplasmic reticulum dysfunction in cerebrovascular disease-therapeutic potential

Keywords: Degenerative diseases; Endoplasmic reticulum; Ischemia; Stroke; Unfolded protein response; 4-PBA; 4-phenylbutyric acid; Aβ; amyloidogenic β-peptide; ATF; activating transcription factor; eIF2α; alpha subunit of the eukaryotic initiation factor 2; ER; e

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

Discovery of an MIT-like atracotoxin family: Spider venom peptides that share sequence homology but not pharmacological properties with AVIT family proteins

Keywords: ACh; acetylcholine; ACTX; atracotoxin; BCA; bicinchoninic acid; Bv8; 8 kDa protein from the skin secretions of toads (Bombina variegata); CHO; Chinese hamster ovary; DDH; disulfide-directed β-hairpin; EST; expressed sequence tag; FLIPR; fluorometric ima

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه

Preferential induction of apoptosis in the rainbow trout macrophage cell line, RTS11, by actinomycin D, cycloheximide and double stranded RNA

Keywords: dsRNA; Macrophages; Apoptosis; Ribotoxic stress; PKR; Fish; RTS11; Cell line;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2005 سفارش ترجمه

RNA interference: From gene silencing to gene-specific therapeutics

Keywords: RNAi; siRNA; shRNA; Disease; Validation; Therapy; AAV; adeno-associated virus; ABCA1; ATP-binding cassette, subfamily A, member 1; Bcl-2; B-cell chronic lymphocytic leukemia/lymphoma 2; BCR-ABL; breakpoint cluster region-protooncogene tyrosine-protein kin

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2005 سفارش ترجمه