دانلود مقالات ISI درباره Pkr + ترجمه فارسی

Murine gammaherpesvirus targets type I IFN receptor but not type III IFN receptor early in infection

Keywords: EBV; Epstein-Barr virus; FBS; fetal bovine serum; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HHV-4; human herpesvirus 4; HHV-8; human herpesvirus 8; hpi; hours post infection; IFN; interferon; IFNAR; interferon α/β receptor; IFN-λR; interferon la

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Rupestonic acid derivative YZH-106 suppresses influenza virus replication by activation of heme oxygenase-1-mediated interferon response

Keywords: IAV; influenza A virus; HO-1; heme oxygenase-1; Nrf2; erythroid 2-related factor 2; ISGs; IFN-stimulated genes; RdRp; RNA-dependent RNA polymerase; TLRs; toll-like receptors; RLR; RIG-I-like receptors; MKP5; MAPK phosphatase 5; IRF3; interferon regulatory

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Movements of HIV-1 genomic RNA-APOBEC3F complexes and PKR reveal cytoplasmic and nuclear PKR defenses and HIV-1 evasion strategies

Keywords: HIV-1; PKR; APOBEC3F; Stress granules; P-bodies; Nuclear pores; Mitosis

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Genomics of human fatty liver disease reveal mechanistically linked lipid droplet-associated gene regulations in bland steatosis and nonalcoholic steatohepatitis

Keywords: ACACB; acetyl-CoA carboxylase beta acetyl-CoA carboxylase beta; ACAT1; acetyl-CoA acetyltransferase 1; ACLY; ATP citrate lyase; AMPK; 5′AMP-activated protein kinase; ASCL1; acyl-CoA synthetase long-chain family member 1; ACSL4; acyl CoA synthetases long

دانلود رایگان متن کامل مقاله ISI 80 صفحه سال انتشار : 2016 سفارش ترجمه

Regulatory roles of Alu transcript on gene expression

Keywords: SINE; short interspersed element; ncRNA; noncoding RNA; AMD; age-related macular degeneration; dsRNA; double stranded RNA; IRAlus; inverted Alu repeats; RPE; retinal-pigmented epithelium; GA; geographic atrophy; ERK; extracellular-signal-regulated kinase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Eukaryotic initiation factor 4AI interacts with NS4A of Dengue virus and plays an antiviral role

Keywords: Dengue virus; NS4A; eIF4AI; PKR;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

A monoclonal antibody binds to threonine 49 in the non-structural 1 protein of influenza A virus and interferes with its ability to modulate viral replication

Keywords: IAV; influenza A virus; NS1; non-structural 1; RBD; RNA binding domain; CPSF30; cleavage and polyadenylation and specificity factor 30; PI3K; phosphoinositide 3-kinase; IFN; interferon; PKR; protein kinase R; OAS; 2′5′-oligoadenylate synthetase; dsRNA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

IL-27 enhances Leishmania amazonensis infection via ds-RNA dependent kinase (PKR) and IL-10 signaling

Keywords: IL-27; IL-10; Leishmania; Macrophages; PKR;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Blueberry anthocyanins ameliorate radiation-induced lung injury through the protein kinase RNA-activated pathway

Keywords: Blueberry anthocyanins; Natural pigment; Radiation; Lung injury; PKR

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Activated PKR inhibits pancreatic β-cell proliferation through sumoylation-dependent stabilization of P53

Keywords: Pancreatic β-cell; Proliferation; PKR; P53; Sumoylation; Ceramide;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Poor growth of human adenovirus-12 compared to adenovirus-2 correlates with a failure to impair PKR activation during the late phase of infection

Keywords: Adenovirus; VA RNA; IFN; PKR; eIF2α;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Hepsin inhibits CDK11p58 IRES activity by suppressing unr expression and eIF-2α phosphorylation in prostate cancer

Keywords: CHO; Chinese hamster ovary; CHX; cycloheximide; DIG; digoxigenin; FACS; fluorescence-activated cell sorting; GCN2; general control non-derepressible-2; HRI; heme regulated inhibitor of translation; IRES; internal ribosome entry sites; ITAFs; IRES trans-ac

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

GSK3β-activation is a point of convergence for HIV-1 and opiate-mediated interactive neurotoxicity

Keywords: CNS; central nervous system; HIV-1; human immunodeficiency virus-1; HAND; HIV-1-associated neurocognitive disorders; cART; combination antiretroviral therapy; Tat; trans-activator of transcription; gp120; glycoprotein 120; GSK3β; glycogen synthase kinase

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Cytopathic BVDV-1 strain induces immune marker production in bovine cells through the NF-κB signaling pathway

Keywords: AP-1; activator protein 1; Bcl3; B-cell leukemia protein 3; BVD; bovine viral diarrhea; BVDV; bovine viral diarrhea virus; cp; cytopathic; DENV; dengue fever virus; EBV; Epstein-Barr virus; hpi; hours post-infection; IFN-β; interferon-beta; IL; interle

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

PKR activation enhances replication of classical swine fever virus in PK-15 cells

Keywords: CSFV; PKR; eIF2α; IFN-β; Innate immune

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Disarmed anthrax toxin delivers antisense oligonucleotides and siRNA with high efficiency and low toxicity

Keywords: ASOs; antisense oligonucleotides; Atx; anthrax toxin; BME; beta-mercaptoethanol; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; E7; early 7; EEA1; early endosomal antigen 1; LFn; Atx lethal factor domain I; GFP; Green fluorescent prote

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice

Keywords: Mouse Model; Stress Signaling; Obesity; Inflammation; CDAA; choline-deficient amino acid defined; CHOP; CCAAT/enhancer-binding protein homologous protein; CSAA; choline-supplemented l-amino acid; ER; endosplasmic reticulum; FFD; fast-food diet; HSC; hepat

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2015 سفارش ترجمه

β-Hydroxy-β-methylbutyrate (HMB) prevents sepsis-induced diaphragm dysfunction in mice

Keywords: Diaphragm; Sepsis; Caspase 3; PKR; β-Hydroxy-β-methylbutyrate (HMB); Proteolysis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

An anti-interferon activity shared by paramyxovirus C proteins: Inhibition of Toll-like receptor 7/9-dependent alpha interferon induction

Keywords: IFN; interferon; PIVs; parainfluenza viruses; MeV; measles virus; NiV; Nipah virus; ORF; open reading frame; SeV; Sendai virus; ISGs; IFN-stimulated genes; ds; double stranded; PKR; protein kinase R; PAMPs; pathogen-associated molecular patterns; IRF; int

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of double-stranded RNA-dependent protein kinase inhibits proliferation of pancreatic β-cells

Keywords: PKR; Diabetes; Pancreatic β-cell; Proliferation; Glucolipitoxicity; Pro-inflammatory cytokine;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Alpha-lipoic acid effects on brain glial functions accompanying double-stranded RNA antiviral and inflammatory signaling

Keywords: Lipoic acid; Double-stranded RNA; TLR3 (Toll-like receptor 3); PKR; Glutamate;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Study of interferon-β antiviral activity against Herpes simplex virus type 1 in neuron-enriched trigeminal ganglia cultures

Keywords: HSV-1; Herpes simplex virus type 1; TG; trigeminal ganglion; IFN; interferon; gB; HSV-1 glycoprotein B; Oas; 2′-5′ oligoadenylate synthetase; RNase-L; latent ribonuclease or 2′,5′-oligoisoadenylate synthetase-dependent RNAse; Pkr; double strande

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

HCV NS5A co-operates with PKR in modulating HCV IRES-dependent translation

Keywords: IRES; internal ribosome entry site; PKR; protein kinase R; HCV IRES; Translation; HCV NS5A; PKR; GBV-C NS5A; GBV-B NS5A;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Mitochondrial EF4 links respiratory dysfunction and cytoplasmic translation in Caenorhabditis elegans

Keywords: C. elegans; Caenorhabditis elegans; WT; wild-type; EF4; elongation factor 4; mtEF4; mitochondrial EF4; mtDNA; mitochondrial DNA; BP; base pairs; ETC; electron transport chain; mtEFTu, mtEFG1 and mtEFTs; mitochondrial elongation factor Tu, G1 and Ts; MMP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Luteolin sensitizes the antiproliferative effect of interferon α/β by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in can

Keywords: luteolin; 3′,4′,5,7-tetrahydroxyflavone; IFN; interferon; JAK; Janus kinase; STAT; signal transducer and activator of transcription; ISRE; interferon α-stimulated response element; PDE; phosphodiesterase; cAMP; cyclic adenosine 3′,5′-monophosphat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

The specific PKR inhibitor C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a neuroinflammatory component

Keywords: Neuroinflammation; PKR; Caspase-3; Oxindole/imidazole C16; Cytokines; Neuroprotection;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Nitazoxanide, an antiviral thiazolide, depletes ATP-sensitive intracellular Ca2+ stores

Keywords: ER stress; N-linked glycans; Flaviviridae; PKR; Intracellular Ca2+; TCTP;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Cyclophilin Inhibitors Reduce Phosphorylation of RNA-Dependent Protein Kinase to Restore Expression of IFN-Stimulated Genes in HCV-Infected Cells

Keywords: Signal Transduction; Cyclosporin; Innate Immunity; Replication; CsA; cyclosporin A; CyP; cyclophilin; HCV; hepatitis C virus; IFN; interferon; IL; interleukin; ISG; IFN-stimulated gene; mRNA; messenger RNA; PKR; double-strand RNA-dependent protein kinase;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2014 سفارش ترجمه

Characterization of porcine P58IPK gene and its up-regulation after H1N1 or H3N2 influenza virus infection

Keywords: P58IPK; the 58-kDa inhibitor of the interferon-induced double-stranded RNA-activated protein kinase; pP58IPK; porcine P58IPK; PKR; dsRNA dependent protein kinase; eIF2a; the eukaryotic translation initiation factor 2 alpha subunit; ER; endoplasmic reticul

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Translational control by eIF2α kinases in long-lasting synaptic plasticity and long-term memory

Keywords: Translation initiation; Synaptic plasticity; long-term memory; Knockout eIF2; GCN2; PERK; PKR; HRI;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Utility of the Sindbis replicon system as an Env-targeted HIV vaccine

Keywords: VEEV; Venezuelan equine encephalitis virus; SFV; Semliki forest virus; SIN; Sindbis virus; nsPs; non-structural proteins; PKR; dsRNA-dependent protein kinase R; 2′5′OAS; 2′5′-linked oligoadenylate synthetase; Env; HIV-1 envelope protein; SIV; simi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

STAT1 requirement for PKR-induced cell cycle arrest in vascular smooth muscle cells in response to heparin

Keywords: IFN; interferon; PKR; protein kinase, RNA-activated; VSMC; vascular smooth muscle cell; Cdk2; cyclin-dependent kinase 2; STAT1; signal transducer and activator of transcription-1; ds; double-stranded; JAK1; janus kinase 1; ATRA; all-trans retinoic acid; F

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Understanding the molecular mechanism(s) of hepatitis C virus (HCV) induced interferon resistance

Keywords: HCV; hepatitis C virus; UTR; untranslated regions; IFN; interferon; ISG; interferon stimulatory genes; IRES; internal ribosome entry site; IFNAR; IFN-α receptor; STAT; signal transducer and activator of transcription; TLR3; toll like receptor 3; DsRNA; d

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

A truncated Danio rerio PKZ isoform functionally interacts with eIF2α and inhibits protein synthesis

Keywords: PKZ; a protein kinase containing Z-DNA binding domains; PKR; protein kinase R; eIF2α; eukaryotic initiation factor 2α; HRI; heme-regulated eIF2α kinase; PERK; RNA-regulated protein kinase (PKR)-like endoplasmic reticulum kinase; GCN2; general control n

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of avian RIG-I responsive genes during influenza infection

Keywords: Microarray; RIG-I; Interferon stimulated genes; IFIT; MX1; OASL; PKR; Influenza A; H5N1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

RNA-dependent protein kinase PKR and the Z-DNA binding orthologue PKZ differ in their capacity to mediate initiation factor eIF2α-dependent inhibition of protein synthesis and virus-induced stress granule formation

Keywords: PKR; PKZ; Protein kinase; Stress granule; Double-stranded RNA; Innate immunity;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

microRNA control of interferons and interferon induced anti-viral activity

Keywords: ADAR; adenosine deaminase acting on RNA; APOBEC; apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like; IFN; interferon; IFN-R; interferon receptor; IRF; interferon regulatory factor; JAK; janus kinase; miR or miRNA; microRNA; NO; nitric oxide;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Prognostic Significance of Combinations of RNA-Dependent Protein Kinase and EphA2 Biomarkers for NSCLC

Keywords: PKR; EphA2; Biomarker; Lung cancer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Rift Valley fever virus NSs inhibits host transcription independently of the degradation of dsRNA-dependent protein kinase PKR

Keywords: Rift Valley fever virus; Bunyavirus; NSs protein; PKR; Interferon; MP-12; Reverse genetics

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Correction de l'astigmatisme au laser Excimer

Keywords: Astigmatisme; Laser; Excimer; Lasik; PKR; Couplage topographique; Eye Tracker; Astigmatism; Laser; Excimer; Lasik; PRK; Link; Eye Tracker;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Zalpha-domains: At the intersection between RNA editing and innate immunity

Keywords: ADAR; adenosine deaminase acting on RNA; A to I; adenosine to inosine; PKR; protein kinase RNA depended; DAI; DNA depended Activator of IRFs; IFN; interferon; CNS; central nervous system; eIF2a; eukaryotic initiation factor 2a; HIV; human immunodeficiency

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Increased Cerebrospinal Fluid Levels of Double-Stranded RNA-Dependant Protein Kinase in Alzheimer's Disease

Keywords: Alzheimer's disease; biomarkers; cerebrospinal fluid; mild cognitive impairment; PKR; tau;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Characterization of the direct physical interaction of nc886, a cellular non-coding RNA, and PKR

Keywords: CIP; calf-intestinal alkaline phosphatase; dsRBM; dsRNA binding motif; dsRNA; double-stranded RNA; EMSA; electrophoretic mobility shift assays; IFN-β; interferon-β; mRNA; messenger RNA; miRNA; microRNA; nc886; non-coding RNA-886; ncRNA; non-coding RNA;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Protein kinase PKR catalytic activity is required for the PKR-dependent activation of mitogen-activated protein kinases and amplification of interferon beta induction following virus infection

Keywords: PKR; Protein kinase; Interferon; Innate immunity

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Dysregulated TLR3-dependent signaling and innate immune activation in superoxide-deficient macrophages from nonobese diabetic mice

Keywords: ROS; reactive oxygen species; T1D; type 1 diabetes; NOD; nonobese diabetic; BM-Mϕ; bone marrow-derived macrophages; MHC; major histocompatibility complex; NOX; NADPH oxidase; Ncf1; neutrophil cytosolic factor 1; TLR; Toll-like receptor; poly(I:C); polyin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Characterization and functional analysis of two PKR genes in fugu (Takifugu rubripes)

Keywords: Kinase; PKR; Fugu; Translation inhibition; NFκB induction

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Oxidative stress increases BACE1 protein levels through activation of the PKR-eIF2α pathway

Keywords: Alzheimer's disease; BACE1; PKR; eIF2α; Oxidative stress; Neuroblastoma cell cultures

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Polyphenol metabolism provides a screening tool for beneficial effects of Onobrychis viciifolia (sainfoin)

Keywords: Onobrychis viciifolia (sainfoin); Soluble polyphenols; Flavonoids; Flavonols; Flavan 3-ols; Dihydroflavonol 4-reductase substrate specificity; Flavonoid enzymes; Flavonoid genes; Screening tool; 5-DLCy; 5-deoxyleucocyanidin; ANR; anthocyanidin reductase;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Dynamic expression profiles of virus-responsive and putative antimicrobial peptide-encoding transcripts during Atlantic cod (Gadus morhua) embryonic and early larval development

Keywords: ADAM; A disintegrin and metalloproteinase domain; AMP; Antimicrobial peptide; ARPC4; Actin-related protein 2/3 complex subunit 4; ATF; Activating transcription factor; BLAST; Basic local alignment search tool; C; Celsius; cAMP; Cyclic adenosine monophosph

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Endoplasmic reticulum stress enhances γ-secretase activity

Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; PS; presenilin; ATF4; activating transcription factor 4; GCN2; general control non-derepressible 2; PKR; protein kinase RNA; PERK; PKR-like ER kinase; HRI; heme-regulated inhibitor; eIF2α; eukary

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه