دانلود مقالات ISI درباره Pp2A + ترجمه فارسی

Citron Rho-interacting kinase mediates arsenite-induced decrease in endothelial nitric oxide synthase activity by increasing phosphorylation at threonine 497: Mechanism underlying arsenite-induced vascular dysfunction

Keywords: EC; endothelial cells; ROS; reactive oxygen species; NO; nitric oxide; eNOS; endothelial NO synthase; PP1; protein phosphatase 1; AMPK; AMP-activated protein kinase; PKC; protein kinase C; PP2A; protein phosphatase 2A; CRIK; citron Rho-interacting kinase;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Microcystin-LR promotes proliferation by activating Akt/S6K1 pathway and disordering apoptosis and cell cycle associated proteins phosphorylation in HL7702 cells

Keywords: Microcystin-LR; Proliferation; PP2A; α4; Akt/S6K1

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

The hyaluronic acid inhibitor 4-methylumbelliferone is an NSMase2 activator-role of Ceramide in MU anti-tumor activity

Keywords: DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethylsulfoxide; fro; fragilis ossium; HA; hyaluronic acid; HAS; HA synthase; HPTLC; high performance thin-layer chromatography; LC-MS/MS; liquid chromatography-tandem mass spectrometry; MES; 2-(N-morp

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

The broken “Off” switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillance

Keywords: PP2A; AKT; CIP2A; SET; Cell cycle; Immune surveillance; Drug resistance

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Quercetin attenuates tau hyperphosphorylation and improves cognitive disorder via suppression of ER stress in a manner dependent on AMPK pathway

Keywords: AMPK; ER stress; NLRP3 inflammasome; Quercetin; Quercetin-3-O-glucuronide; Tau phosphorylation; Compound C (PubChem CID: 11524144); Metformin (PubChem CID: 14219); Okadaic acid (PubChem CID: 446512); Quercetin (PubChem CID: 5280343); Quercetin-3-O-glucuro

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Essential role of HDAC6 in the regulation of PD-L1 in melanoma

Keywords: Histone deacetylases; HDAC6; PD-L1; STAT3; PP2A; Melanoma; Nexturastat; Tubastatin A;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

27-Hydroxycholesterol increases Myc protein stability via suppressing PP2A, SCP1 and FBW7 transcription in MCF-7 breast cancer cells

Keywords: Breast cancer; 27-Hydroxycholesterol; Myc protein stability; PP2A; SCP1; FBW7; 27-HC; 27-hydroxycholesterol; E2; 17β-estradiol; ER-α; estrogen receptor alpha; LXR-α; liver X receptor alpha; SERM; selective estrogen receptor modulator; Myc: v-myc avian

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه

Telomerase reverse transcriptase induces basal and amino acid starvation-induced autophagy through mTORC1

Keywords: Autophagy; Cell viability; Human telomerase reverse transcriptase (hTERT); Mammalian target of rapamycin complex 1 (mTORC1); Telomerase; AMPK; AMP-activated protein kinase; DMEM; Dulbecco's Modified Eagle's medium; EBSS; Earle's balanced salt solution; ER

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Negative regulation of the FOXO3a transcription factor by mTORC2 induces a pro-survival response following exposure to ultraviolet-B irradiation

Keywords: mTOR; mammalian target of rapamycin; UVB; ultraviolet-B; NMSC; non-melanoma skin cancer; mTORC1; mTOR complex 1; mTOC2; mTOR complex 2; AKT/PKB; protein kinase B; SCC; squamous cell carcinoma; ERK; extracellular-signal-regulated kinases; MEK; mitogen-acti

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response

Keywords: Netrin; UPR; Hepatocyte; Translation; ATF6; activated transcription factor 6; CMV; cytomegalovirus; DAPK; death-associated protein kinase; DMS; dimethyl sulfate; DR; dependence receptor; DTT; dithiothreitol; eIF2α; Eukaryotic translation initiation facto

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Interleukin-6 influences stress-signalling by reducing the expression of the mTOR-inhibitor REDD1 in a STAT3-dependent manner

Keywords: HIF; Hypoxia-inducible Factor; IL-6; Interleukin 6; IRS1; Insulin Receptor Substrate 1; Jak; Januskinase; mTOR; Mammalian Target of Rapamycin; MEF; Mouse Embryonic Fibroblast; NF-κB; Nuclear Factor kappa B; n.s.; non-significant; MAPK; Mitogen-Activated

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Protein phosphatase role in adenosine A1 receptor-induced AMPA receptor trafficking and rat hippocampal neuronal damage in hypoxia/reperfusion injury

Keywords: Hippocampal neurotoxicity; Cerebral ischemia; Adenosine A1 receptor; AMPAR trafficking; Serine/threonine protein phosphatase; Adenosine-induced persistent synaptic depression; CPA; N6-cyclopentyl adenosine; DPCPX; 8-cyclopentyl-1,3-dipropylxanthine; APSD;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

PGC-1α ameliorates AngiotensinII-induced eNOS dysfunction in human aortic endothelial cells

Keywords: PGC-1α; eNOS; PI3K/Akt; PP2A; Endothelial dysfunction;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Altered regulation of the Spry2/Dyrk1A/PP2A triad by homocysteine impairs neural progenitor cell proliferation

Keywords: neurogenesis; neural progenitor cells; homocysteine; Spry2; Dyrk1A; PP2A;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

ER functions of oncogenes and tumor suppressors: Modulators of intracellular Ca2 + signaling

Keywords: a.a.; amino acid; ATP; adenosine triphosphate; BH domain; Bcl-2-homology domain; BI-1; Bax inhibitor-1; BIRD-2; Bcl-2/IP3R disruptor-2; BRCA1; breast and ovarian cancer susceptibility gene 1; [Ca2 +]cyt; cytosolic Ca2 + concentration; CLL; chronic lymph

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

Knockdown of microRNA-195 contributes to protein phosphatase-2A inactivation in rats with chronic brain hypoperfusion

Keywords: Chronic brain hypoperfusion; miR-195; PP2A; PME-1; LCMT-1;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Conjugates of podophyllotoxin and norcantharidin as dual inhibitors of topoisomeraseⅡ and protein phosphatase 2A

Keywords: Podophyllotoxin; Cantharidin; TOP-Ⅱ; PP2A; Cell-cycle arrest;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation

Keywords: 4E-BP1; eukaryotic initiation factor 4E binding protein 1; AMPK; AMP-activated protein kinase; Atg13; autophagy-related 13; FIP200; 200 kilodalton focal adhesion kinase family kinase-interacting protein; GAP; GTPase activator protein; GATOR; GAP activity

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular and cellular mechanisms linking inflammation to insulin resistance and β-cell dysfunction

Keywords: AMPK; AMP-activated protein kinase; ATM; adipose tissue macrophages; CCL; chemokine (C-C motif) ligand; CCR2; chemokine (C-C motif) receptor 2; CX3CL1; chemokine (C-X3-C motif) ligand 1; CX3CR1; chemokine (C-X3-C motif) receptor; CXCL; CXC chemokine ligan

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibitor-1 and -2 of PP2A have preference between PP2A complexes

Keywords: PP2A; B-subunit specificity; I1PP2A; I2PP2A; Inhibitor protein; PP2A; protein phosphatase 2A; I1PP2A; Inhibitor-1 of PP2A; I2PP2A; Inhibitor-2 of PP2A; PPP; phosphoprotein phosphatase; CSF; cyto-static factor; OA; okadaic acid;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Fluorocitrate induced the alterations of memory-related proteins and tau hyperphosphorylation in SD rats

Keywords: FC; fluorocitrate; GSK-3β; glycogen synthase kinase-3β; pS9; phosphorylated GSK-3β at serine 9; PP2A; protein phosphatase-2A; PP2AC; PP2A catalytic subunit; pY307; phosphorylated PP2A catalytic subunit at tyrosine-307; CREB; cAMP response element bindi

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Could caveolae be acting as warnings of mitochondrial ageing?

Keywords: ERK; extracellular signal-regulated kinases; FAK; focal adhesion kinase; Nrf2; nuclear erythroid 2 p45-related factor-2; Shp-2; SH2 domain-containing phosphatase-2; CSK; c-Src tyrosine kinase; HO-1; hemeoxigenase 1; HIF1; hypoxia induced factor 1; SHP-2;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Diarachidonoylphosphoethanolamine induces necrosis/necroptosis of malignant pleural mesothelioma cells

Keywords: DAPE; 1,2-diarachidonoyl-sn-glycero-3-phosphoethanolamine; MPM; malignant pleural mesothelioma; PI; propidium iodide; AV; annexin V; Nec-1; necrostatin-1; ROS; reactive oxygen species; MPT; mitochondrial permeability transition; CypD; cyclophilin D; CsA;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

The role of PP2A-associated proteins and signal pathways in microcystin-LR toxicity

Keywords: Microcystin-LR; PP2A; Proteins; Signal pathways; Toxicity

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Small-conductance Ca2+-activated K+ channels and cardiac arrhythmias

Keywords: AERP; atrial effective refractory period; AF; atrial fibrillation; AP; action potential; APD; action potential duration; CaM; calmodulin; CK2; casein kinase II; EAD; early afterdepolarization; HF; heart failure; MLC2; myosin light chain-2; PP2A; protein p

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Tissue specific expression of SG2NA is regulated by differential splicing, RNA editing and differential polyadenylation

Keywords: UTR; untranslated region; RNA; ribonucleic acid; DNA; deoxyribonucleic acid; SG2NA; S/G2 nuclear autoantigen; PP2A; Protein phosphatase 2A; STRIPAK; Striatin-interacting phosphatase and kinase; CCM3; Cerebral cavernous malformations 3; Akt; protein kinase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Lipid rafts regulate PCB153-induced disruption of occludin and brain endothelial barrier function through protein phosphatase 2A and matrix metalloproteinase-2

Keywords: PCB153; 2,2′,4,4′,5,5′-hexachlorobiphenyl; PCBs; polychlorinated biphenyls; TJ; tight junction; DRM; detergent-resistant membrane; PP2A; protein phosphatase 2A; MMP; matrix metalloproteinase; BBB; blood-brain barrier; MβCD; methyl-beta-cyclodextr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Hypoxia-induced IL-32β increases glycolysis in breast cancer cells

Keywords: ECAR; extracellular acidification rate; HIF-1; hypoxia inducible factor-1; IL-32; interleukin-32; LDH-A; lactate dehydrogenase A; OCR; oxygen consumption rate; OXPHOS; oxidative phosphorylation; PDK1; pyruvate dehydrogenase kinase; PFKFB4; fructose-2,6-bi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Protein phosphatase 2A (PP2A) activation promotes axonal growth and recovery in the CNS

Keywords: Axon growth; Spinal cord injury; PP2A; EGFR; CRMP2; Y307 phosphorylation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of protein phosphatase-1 and -2A decreases the chemosensitivity of leukemic cells to chemotherapeutic drugs

Keywords: BSA; bovine serum albumin; CHAPS; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate; CLA; calyculin A; CPI-17; C-kinase phosphatase-1 inhibitory protein of 17 kDa; DMSO; dimethyl sulfoxide; DNR; daunorubicin; EDTA; ethylenediaminetetraacetic acid

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Reference gene validation for qRT-PCR based gene expression studies in different developmental stages and under biotic stress in apple

Keywords: 18S; 18S ribosomal RNA; ACT; actin; APRT; adenine phosphoribosyl transferases; CT; cycle threshold; CYP; cyclophilin; EF-1α; elongation factor-1α; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; PP2A; protein phosphatase 2A; qRT-PCR; quantitative real-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Ceramide signalling impinges on Sit4p and Hog1p to promote mitochondrial fission and mitophagy in Isc1p-deficient cells

Keywords: ALP; alkaline phosphatase; ATP; adenosine triphosphate; CLS; chronological lifespan; COX; cytochrome c oxidase; CR; caloric restriction; EDTA; ethylenediamine tetraacetic acid; ER; endoplasmic reticulum; FCCP; carbonyl cyanide p-(trifluoromethoxy)phenylhy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Low-dose endothelial monocyte-activating polypeptide-II increases permeability of blood-tumor barrier via a PKC-ζ/PP2A-dependent signaling mechanism

Keywords: Endothelial monocyte-activating polypeptide-II; Blood-tumor barrier; Permeability; PKC-ζ; PP2A; Occludin;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Free-radical first responders: The characterization of CuZnSOD and MnSOD regulation during freezing of the freeze-tolerant North American wood frog, Rana sylvatica

Keywords: ALS; amyotrophic lateral sclerosis; AMPK; 5′ adenosine monophosphate-activated protein kinase; Cm; the denaturant concentration at which half of the protein is unfolded; CuZnSOD; copper and zinc containing SOD; DEAE+; diethylaminoethyl cellulose; DEPC;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Phosphorylation-independent mTORC1 inhibition by the autophagy inducer Rottlerin

Keywords: AMPK, AMP-activated protein kinase; mTOR, mammalian target of rapamycin; p70S6K, phosphoprotein 70 ribosomal protein S6 kinase; 4EBP-1, Eukaryotic translation initiation factor 4E-binding protein 1; Bcl2, B-cell lymphoma/leukemia-2; Becl-1, Beclin-1; PP2A

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-9 regulates steroid-resistant airway hyperresponsiveness by reducing protein phosphatase 2A activity

Keywords: MicroRNA; pulmonary macrophages; innate immunity; protein phosphatase 2A; steroid-resistant airway hyperresponsiveness; AAL(S); (S)-2-Amino-4-(4-[heptyloxy]phenyl)-2-methylbutan-1-ol; AHR; Airway hyperresponsiveness; ant-9; Antagomir-9; DEX; Dexamethasone

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Redox regulation of metabolic and signaling pathways by thioredoxin and glutaredoxin in NOS-3 overexpressing hepatoblastoma cells

Keywords: ACO; aconitase; ASK1; apoptosis signal-regulating kinase 1; Bcl-2; B-cell lymphoma 2; CaM; calmodulin; CD95; cluster of differentiation 95; DTNB; 5,5-dithio-bis-2-nitrobenzoic acid; ELISA; enzyme-linked immunosorbent assay; GAPDH; glyceraldehyde-3-phospha

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Cross talk between PI3K-AKT-GSK-3β and PP2A pathways determines tau hyperphosphorylation

Keywords: Alzheimer's disease; GSK-3β; LCMT-1; PME-1; PP2A; Tau phosphorylation;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of protein phosphatase 2A tumor suppressor as potential treatment of pancreatic cancer

Keywords: PP2A; Dasatinib; Pancreatic cancer; Phenothiazine; FTY-720

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Gestational marginal zinc deficiency impaired fetal neural progenitor cell proliferation by disrupting the ERK1/2 signaling pathway

Keywords: ERK1/2; extracellular signal-regulated kinases 1/2; NPC; neural progenitor cell; E; embryonic day; MEK1/2; mitogen-activated ERK1/2 kinases 1/2; PP2A; protein phosphatase 2A; NGF; nerve growth factor; BDNF; brain-derived neurotrophic factor; BrdU; bromode

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

Proteomic profile of the skin mucus of farmed gilthead seabream (Sparus aurata)

Keywords: Apo-A1; apolipoprotein-A1; ENOA; enolase; FABP7; brain-type fatty acid binding protein; FBPA; fructose-bisphosphate aldolase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HSC70; heat-shock cognate 70 kDa protein; HBB; beta globin; LPS; lipopolysaccha

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2015 سفارش ترجمه

Protein tyrosine phosphatase 1B (PTP1B): A key regulator and therapeutic target in liver diseases

Keywords: PTKs; protein tyrosine kinases; PTPs; protein tyrosine phosphatases; PTP1B; protein tyrosine phosphatase 1B; NAFLD; non-alcoholic fatty liver disease; HCC; hepatocellular carcinoma; DSPs; dual specificity phosphatases; LMW; low molecular weight; RPTPs; tr

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2015 سفارش ترجمه

Nuclear Localization of DNAJB6 Is Associated With Survival of Patients With Esophageal Cancer and Reduces AKT Signaling and Proliferation of Cancer Cells

Keywords: Prognostic Marker; Tissue Microarray; Signal Transduction; Tumor Suppressor; AKT; v-akt murine thymoma viral oncogene homolog 1; CI; confidence interval; DNAJB6; DnaJ (Hsp40) homolog, subfamily B, member 6; EAC; esophageal adenocarcinoma; ESCC; esophageal

دانلود رایگان متن کامل مقاله ISI 73 صفحه سال انتشار : 2015 سفارش ترجمه

Is RK-682 a promiscuous enzyme inhibitor? Synthesis and in vitro evaluation of protein tyrosine phosphatase inhibition of racemic RK-682 and analogues

Keywords: Tyrosine phosphatases inhibitors; Natural 3-acyl-5-hydroxymethyltetronic acid; RK-682; Meldrum's acid derivatives; Enzyme inhibition; Promiscuous enzyme inhibition; PTP-1B; protein tyrosine phosphatase 1B; LMW-PTP; low molecular weight protein tyrosine ph

دانلود رایگان متن کامل مقاله ISI 105 صفحه سال انتشار : 2015 سفارش ترجمه

Resistin regulates the expression of plasminogen activator inhibitor-1 in 3T3-L1 adipocytes

Keywords: PAI-1; plasminogen activator inhibitor-1; PI3K; phosphoinositide 3-kinase; PP2A; protein phosphatase 2A; GLUT4; glucose transporter type 4; ChREBP; carbohydrate responsive element-binding protein; PPARγ; peroxisome proliferator activated receptor γ; C/E

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Expression and mechanism of regulation of PP2A/Pr65 in ameloblastoma

Keywords: Ameloblastoma; PP2A; Immunohistochemistry; Western blot;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

CIP2A and PP2A in human leptomeninges, arachnoid granulations and meningiomas

Keywords: Arachnoid granulations; CIP2A; Leptomeninges; Meningioma; PP2A

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of a protein phosphatase 2A family member that regulates cell cycle progression in Trypanosoma brucei

Keywords: Phosphoprotein phosphatase; PP2A; Okadaic acid; Cell cycle regulation; Basal bodies; Trypanosoma brucei

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Glutamate transporter type 3 regulates mouse hippocampal GluR1 trafficking

Keywords: ACSF; artificial cerebrospinal fluid; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; DMSO; dimethyl sulfoxide; EAAT; excitatory amino acid transporter; PKA; protein kinase A; PP2A; protein phosphatase 2A; α-Amino-3-hydroxy-5-methy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular cloning and characterization of the β-catenin gene from fine-wool sheep

Keywords: ORF; open reading frame; CDS; coding sequence; RACE; rapid amplification of cDNA ends; GSK3β; glycogen synthase kinase 3β; CKI; casein kinase I; AA; amino acid; APC; adenoma polyposis coli; PP2A; protein phosphatase 2A; LRP; low-density lipoprotein rece

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه