دانلود مقالات ISI درباره Pparα + ترجمه فارسی

Leucine stimulates PPARβ/δ-dependent mitochondrial biogenesis and oxidative metabolism with enhanced GLUT4 content and glucose uptake in myotubes

Keywords: Mitochondrial biogenesis; PPARα; PPARβ/δ; PPARγ; PGC-1α;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of the new thiazolidine derivative LPSF/GQ-02 on hepatic lipid metabolism pathways in non-alcoholic fatty liver disease (NAFLD)

Keywords: NAFLD; Thiazolidinediones; LPSF/GQ-02; PPARα; AMPK and SREBP-1c;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

Alpha-lipoic acid attenuates endoplasmic reticulum stress-induced insulin resistance by improving mitochondrial function in HepG2 cells

Keywords: ALA; alpha-lipoic acid; ER stress; endoplasmic reticulum (ER) stress; HepG2; hepatoblastoma cell line; Tun; tunicamycin; OXPHOS; oxidative phosphorylation; Olig; oligomycin; T2DM; type 2 diabetes mellitus; IRS; insulin receptor substrate; PI3K; phosphatid

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Iridoid-loganic acid versus anthocyanins from the Cornus mas fruits (cornelian cherry): Common and different effects on diet-induced atherosclerosis, PPARs expression and inflammation

Keywords: Cornelian cherry; Iridoids; Anthocyanins; Loganic acid; Atherosclerosis; Hypercholesterolemia; PPARα; PPARγ; IL-6; TNFα;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

An Intestinal Microbiota-Farnesoid X Receptor Axis Modulates Metabolic Disease

Keywords: Bile Acids; Farnesoid X Receptor; Metabolic Disease; Ceramides; BSH; bile salt hydrolase; CA; cholic acid; cAMP; cyclic adenosine monophosphate; CDCA; chenodeoxycholic acid; CYP; cytochrome P450s; CYP7A1; CYP with cholesterol 7α-hydroxylase; DCA; deoxych

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

A conjugated fatty acid present at high levels in bitter melon seed favorably affects lipid metabolism in hepatocytes by increasing NAD+/NADH ratio and activating PPARα, AMPK and SIRT1 signaling pathway

Keywords: ACC; acetyl-CoA carboxylase; ACOX; acyl-CoA oxidase; AMPK; AMP-activated protein kinase; BMSO; bitter melon seed oil; c9,t11-CLA; cis-9, trans-11 isomer of conjugated linoleic acid; α-ESA; α-eleostearic acid; FASN; fatty acid synthase; FOXO1; forkhead b

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

Carnitine palmitoyltransferase 1C: From cognition to cancer

Keywords: ACC; acetyl-CoA carboxylase; ACO; aconitase; AICAR; 5-aminoimidazole-4-1-b-d-ribofuranoside; AMPK; AMP-dependent protein kinase; Arc; Arcuate; BSX; brain-specific homeobox; cAMP; cyclic AMP; CNS; central nervous system; COT; carnitine octanoyltransferase;

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2016 سفارش ترجمه

Cornus mas L. (cornelian cherry), an important European and Asian traditional food and medicine: Ethnomedicine, phytochemistry and pharmacology for its commercial utilization in drug industry

Keywords: AAE; ascorbic acid equivalent; AAPH; 2,2′-Azobis(2-amidinopropane) dihydrochloride; ABTS; 2,2-Azinobis-3-ethylbenzothiazoline-6-sulfonic acid; AD; Alzheimer's disease; AFLP; Amplified fragment length polymorphism; AIP; Atherogenic index parameter; ALP;

دانلود رایگان متن کامل مقاله ISI 71 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewPPARα regulates tumor progression, foe or friend?

Keywords: PPARα; Ligands; Tumorigenesis;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Protective effects of aerobic swimming training on high-fat diet induced nonalcoholic fatty liver disease: Regulation of lipid metabolism via PANDER-AKT pathway

Keywords: Exercise; Fatty acid transport; Lipogenesis; Fatty acid β-oxidation; PPARα; FOXO1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Ontogenic expression of human carboxylesterase-2 and cytochrome P450 3A4 in liver and duodenum: Postnatal surge and organ-dependent regulation

Keywords: CES2; carboxylesterase-2; CYP3A4; cytochrome P450 3A4; GAPDH; glyceradehyde-3-phosphate dehydrogenase; GI; gastrointestinal; PBS; phosphate buffered saline; PPARα; peroxisome proliferator-activated receptor-α; RT-qPCR; reverse transcription-quantitative

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Fenofibrate insulates diacylglycerol in lipid droplet/ER and preserves insulin signaling transduction in the liver of high fat fed mice

Keywords: DNL; de novo lipogenesis; IRS1; insulin-receptor-substrate 1; FB; fenofibrate; GTT; glucose tolerance test; β-HAD; β3-hydroxyacyl-CoA dehydrogenase; LCACoA; long chain acyl-CoA; DAG; diacylglycerol; GSK3β; glycogen synthase kinase; SREBP-1c; sterol reg

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of PPAR alpha by fenofibrate inhibits apoptosis in vascular adventitial fibroblasts partly through SIRT1-mediated deacetylation of FoxO1

Keywords: PPARα; SIRT1; FoxO1; Apoptosis; Vascular adventitial fibroblasts;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Sirt1 mediates the effects of a short-term high-fat diet on the heart

Keywords: Sirt1; PPARα; High-fat diet; Cardiac dysfunction; Metabolism;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Human FABP1 T94A variant enhances cholesterol uptake

Keywords: C/EBPα; CCAAT/enhancer binding protein alpha; CETP; cholesteryl ester transfer protein; CPT1A; carnitine palmitoyl transferase IA, liver; CPT2; carnitine palmitoyl-CoA transferase II; CVD; cardiovascular disease; FABP1; human liver fatty acid binding pro

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Original ResearchOat consumption reduced intestinal fat deposition and improved health span in Caenorhabditis elegans model

Keywords: Oats; C elegans model; Insulin sensitivity; Lipid metabolism; Health span; Avns; avenanthramides; IFD; intestinal fat deposition; IGF; insulin-like growth factor; PPARα; peroxisome proliferator activator alpha; PPR; pharyngeal pumping rate; Q-RT-PCR; qua

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Red bayberry extract prevents high-fat diet-induced metabolic disorders in C57BL/6 mice

Keywords: Red bayberry; Metabolic syndrome; High-fat diet; LXRα; PPARα; Myricitrin (PubChem CID: 5281673); Isoquercitrin (PubChem CID: 5280804); Quercitrin (PubChem CID: 5280459); Myricetin (PubChem CID: 5281672); Quercetin (PubChem CID: 5280343); Gallic acid (Pu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

BPA-induced DNA hypermethylation of the master mitochondrial gene PGC-1α contributes to cardiomyopathy in male rats

Keywords: ATP5E; ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit; ATP5O; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit; BPA; bisphenol A; CpG; cytosine phosphate guanine; DNMT3A; DNA methyltransferase 3A; DNMT3B; DNA me

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Astragalus polysaccharides repress myocardial lipotoxicity in a PPARalpha-dependent manner in vitro and in vivo in mice

Keywords: Cardiomyopathy; Lipotoxity; Lipid metabolism; H9c2; Cardiomyocytes; PPARα;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Cocoa and cocoa flavanol epicatechin improve hepatic lipid metabolism in in vivo and in vitro models. Role of PKCζ

Keywords: AKT; protein kinase B; AMPK; AMP-activated protein kinase; aPKC; atypical protein kinase C; Cho; cholesterol; EC; (−)-epicatechin; EDTA; ethylenediaminetetraacetic acid; NEFA; non-esterified fatty acids; PFA; paraformaldehyde; PKC; protein kinase C; PMS

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Mitochondria in peroxisome-deficient hepatocytes exhibit impaired respiration, depleted DNA, and PGC-1α independent proliferation

Keywords: Peroxisomes; Mitochondrial DNA; Oxidative phosphorylation; Biogenesis; PPARα; PGC-1α;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting strategies on miRNA-21 and PDCD4 for glioblastoma

Keywords: GBM; glioblastoma multiforme; miRNAs; microRNAs; PDCD4; programmed cell death 4; EMT; epithelial-mesenchymal transition; JNK; Jun N-terminal protein kinase; PTEN; phosphatase and tensin homolog; PI3K/AKT; phosphatidylinositol-3 kinase/Akt; MAPK/ERK; mit

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

High fructose consumption induces DNA methylation at PPARα and CPT1A promoter regions in the rat liver

Keywords: Epigenetics; Metabolic syndrome; Nutrition; Corn syrup; Gene expression; Dyslipidemia; PPARα; peroxisome proliferator-activated receptor α; CPT1&Agr; carnitine palmitoyltransferase 1A; LDLR; low density lipoprotein receptor; MTTP; microsomal triglycerid

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2015 سفارش ترجمه

The liver-selective NO donor, V-PYRRO/NO, protects against liver steatosis and improves postprandial glucose tolerance in mice fed high fat diet

Keywords: Nitric oxide; Hepatoprotection; Liver steatosis; Glucose tolerance; Fatty acid metabolism; ABCA1; ATP-binding cassette transporter family member 1; ACC; native isoform acetyl-CoA carboxylase; Akt; serine/threonine-protein kinase; ALT; alanine aminotransfe

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2015 سفارش ترجمه

Herbal composition Gambigyeongsinhwan (4) from Curcuma longa, Alnus japonica, and Massa Medicata Fermentata inhibits lipid accumulation in 3T3-L1 cells and regulates obesity in Otsuka Long-Evans Tokushima Fatty rats

Keywords: Alnus japonica; Curcuma longa; Massa Medicata Fermentata; PPARα; Lipid accumulation; Antiobesity;

دانلود رایگان متن کامل مقاله ISI 63 صفحه سال انتشار : 2015 سفارش ترجمه

The dipeptide H-Trp-Glu-OH (WE) shows agonistic activity to peroxisome proliferator-activated protein-α and reduces hepatic lipid accumulation in lipid-loaded H4IIE cells

Keywords: WE; H-Trp-Glu-OH; PPARs; peroxisome proliferator-activated proteins; LBD; ligand-binding domain; SPR; surface plasmon resonance; TR-FRET; time-resolved fluorescence resonance energy transfer; FATP4; fatty-acid transport protein 4; ACS; acyl-CoA synthetase

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of nuclear receptor NR5A2 increases Glut4 expression and glucose metabolism in muscle cells

Keywords: NR5A2; nuclear receptor subfamily 5, group A, member; GLUT4; glucose transporter 4; Acc2; acetyl-CoA carboxylase 2; DLPC; dilauroyl phosphatidylcholine; CEPT; Cholesteryl ester transfer protein; CYP7A1; cholesterol 7 alpha-hydroxylase; CYP8B1; sterol 12-a

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleThyrotropin increases hepatic triglyceride content through upregulation of SREBP-1c activity

Keywords: NAFLD; non-alcoholic fatty liver disease; SCH; subclinical hypothyroidism; TSH; thyrotropin; T4; free thyroxine; TG; triglyceride; SREBP-1c; sterol regulatory element-binding protein-1c; PPARα; peroxisome proliferator-activated receptor α; AMPK; AMP-act

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

NPC1, intracellular cholesterol trafficking and atherosclerosis

Keywords: NPC1; Niemann-Pick type C1; LE/LY; late endosome/lysosome; LDL; low-density lipoprotein; LDL-C; LDL-cholesterol; ER; endoplasmic reticulum; SSD; sterol-sensing domain; NTD; N-terminal domain; apoE; apolipoprotein E; LXR; liver X receptor; OSBP; oxysterolÂ

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Urokinase-type plasminogen activator (uPA) stimulates triglyceride synthesis in Huh7 hepatoma cells via p38-dependent upregulation of DGAT2

Keywords: Urokinase; Triglycerides; DGAT2; p38; PPARα; Fatty acids;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Creatine reduces hepatic TG accumulation in hepatocytes by stimulating fatty acid oxidation

Keywords: ABCA1; ATP binding cassette protein; AMPK; adenosine monophosphate-activated protein kinase; CT; CTP:phosphocholine cytidylyltransferase; DGAT; acyl CoA:diacylglycerol acyltransferase; HDL; high density lipoproteins; HFD; high-fat diet; HCD; high-carbohyd

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

mRNA expression of genes regulating lipid metabolism in ringed seals (Pusa hispida) from differently polluted areas

Keywords: ACOX1; acyl-coenzyme A oxidase 1; ADIPOQ; adiponecin; CD36; cluster of differentiation 36; FABP4; fatty acid binding protein 4; NR; nuclear receptors; POPs; persistent organic pollutants; PPARα; peroxisome proliferator-activated receptor alpha; PPARβ; p

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of pirinixic acid derivatives bearing a 2-aminothiazole moiety combines dual PPARα/γ activation and dual 5-LO/mPGES-1 inhibition

Keywords: PPARα; PPARγ; Inflammation; 5-LO; mPGES-1; Cancer;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Dietary umbelliferone attenuates alcohol-induced fatty liver via regulation of PPARα and SREBP-1c in rats

Keywords: Alcoholic fatty liver; Lipid metabolism; SREBP-1c; PPARα; Umbelliferone;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Role of the ubiquitin-proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice

Keywords: ATF6; activating transcription factor 6; ATGL; adipose triglyceride lipase; AKO; adipose triglyceride lipase knockout; AMC; amino-4-methylcoumarin; CHOP; C/EBP homologous protein; EDTA; ethylenediaminetetraacetic acid; ER; endoplasmic reticulum; FA; fatty

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleMindin/Spondin 2 inhibits hepatic steatosis, insulin resistance, and obesity via interaction with peroxisome proliferator-activated receptor α in mice

Keywords: IR; insulin resistance; WT; wild type; KO; knockout; TG; transgenic; NTG; non-transgenic; NC; normal chow; HFD; high-fat diet; PPARα; peroxisome proliferator-activated receptor alpha; ECM; extracellular matrix; NL; normal liver; NAFLD; non-alcoholic fatt

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

β-Lapachone alleviates alcoholic fatty liver disease in rats

Keywords: β-Lapachone; Fatty liver diseases; AMPK; PPARα; Metabolic syndrome;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Liquid fructose downregulates Sirt1 expression and activity and impairs the oxidation of fatty acids in rat and human liver cells

Keywords: ACO; acyl-CoA oxydase; AMPK; AMP-activated protein kinase; APRT; adenosyl phosphoribosyl transferase); ACC; acetyl-CoA carboxylase); ChREBP; carbohydrate response element binding protein; CYP4A1; cytochrome P450 4A1; FAS; fatty acid synthase; Foxa2; forkh

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Cholesterol biosynthesis and ER stress in peroxisome deficiency

Keywords: Peroxisomes; Cholesterol; Isoprenoid; Pex2; SREBP-2; ER stress; Integrated stress response; Unfolded protein response; Zellweger syndrome; ACAT; acetoacetyl-CoA thiolase; ATF; activating transcription factor; BA; bile acid; CHOP; C/EBP homologous protein;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

A map of the PPARα transcription regulatory network for primary human hepatocytes

Keywords: PPARα; peroxisome proliferator-associated receptor alpha; ChIP-seq; chromatin immunoprecipitation and next-generation sequencing; TT21C; Toxicity pathways; High-throughput technologies;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Targeting inflammation: New therapeutic approaches in chronic kidney disease (CKD)

Keywords: ACEI; Angiotensin-converting enzyme inhibitor; ARB; angiotensin receptor blocker; CKD; chronic kidney disease; DN; diabetic nephropathy; ESRD; end stage renal disease; PEA; palmitoylethanolamide; PPARα; proliferator activated receptor alpha; TNF-α; tumo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Peroxisome proliferator-activated receptor-α activation and excess energy burning in hepatocarcinogenesis

Keywords: PPARα; Liver tumors; Fatty acid oxidation; Energy combustion; Oxidative stress; Med1; PPAR; peroxisome proliferator-activated receptor; PPRE; peroxisome proliferator-response element; Med1; Mediator complex subunit 1; ACOX1; acyl-CoA oxidase-1; l-PBE/EHH

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Disturbances in cholesterol, bile acid and glucose metabolism in peroxisomal 3-ketoacylCoA thiolase B deficient mice fed diets containing high or low fat contents

Keywords: Peroxisomal 3-ketoacyl-CoA thiolase B; Hypoglycemia; De novo biosynthesis of cholesterol; Bile acids; Lathosterol; ThA; 3-ketoacyl-CoA thiolase A; ThB; 3-ketoacyl-CoA thiolase B; FAO; fatty acid oxidation; ACOX1; acyl-CoA-oxidase 1; MFP1; peroxisomal mult

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Hepatic SIRT1 Attenuates Hepatic Steatosis and Controls Energy Balance in Mice by Inducing Fibroblast Growth Factor 21

Keywords: Liver-Specific Disruption of Sirt1; Hepatocyte-Derived Hormone; Metabolic Homeostasis; Obesity; Ad; adenovirus; BAT; brown adipose tissue; CPT1α; carnitine palmitoyltransferase 1α; FAS; fatty acid synthase; FGF21; fibroblast growth factor 21; MCAD; medi

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2014 سفارش ترجمه

Guía de práctica clínica de la ESC sobre diabetes, prediabetes y enfermedad cardiovascular, en colaboración con la European Association for the Study of Diabetes

Keywords: Guías de Práctica Clínica; Diabetes mellitus; Enfermedad cardiovascular; Intolerancia a la glucosa; Manejo del paciente; Prevención; Epidemiología; Pronóstico; Diagnóstico; Factores de riesgo; Tratamiento farmacológico; Intervenciones coronarias;

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2014 سفارش ترجمه

Fenofibrate, a peroxisome proliferator-activated receptor α ligand, prevents abnormal liver function induced by a fasting-refeeding process

Keywords: Fasting-refeeding; PPARα; Fenofibrate; Triglyceride; Fatty acid oxidation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Research ArticlePost-transcriptional activation of PPAR alpha by KLF6 in hepatic steatosis

Keywords: KLF6; PPARα; TRB3; PEPCK; CD36; miRNA-10b; NAFLD;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Fenofibrate A peroxisome proliferator activated receptor-α agonist treatment ameliorates Concanavalin A-induced hepatitis in rats

Keywords: PPARα; Fenofibrate; Concanavalin A; Portal pressure; Malondialdehyde; Tumor necrosis; Factor alpha;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Safety evaluation and nutritional composition of a Fraxinus excelsior seed extract, FraxiPure™

Keywords: AE; adverse event; ALT; alanine transaminase; AST; aspartate aminotransferase; AUC; area under the curve; CB; cytokinesis-blocked; CRF; case report form; FBS; fetal bovine serum; GCP; Good Clinical Practice; GGTP; gamma-glutamyl transpeptidase; GMP; Good

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: Implications for vascular aging

Keywords: SIRT1; Endothelial dysfunction; NADPH oxidase; PPARα;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه